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신영일,Sheen, Yeong-Il 한국한의학연구원 1996 한국 한의학연구소 논문집 Vol.2 No.1
Hyang-Yack-Ku-Keup-Bang(鄕藥救急方) is our own, medical work written about the middle of the time of Korea Dynasty. I restored and researched this book because it needed to be illuminated about its medico-historic value and then I came to some conclusions as follows. 1. Hyang-Yack-Ku-Keup-Bang was published in Dae-jang-do-kam(大藏都監) of Kanghaw island(江華島) about the middle of Korea Dynasty. Choi Ja-ha(崔自河) republished it on original publication ground in Euiheung(義興) of Kyungsang-Province(慶尙道) in July, Taejong's(太宗) 17th year of Chosen Dynasty (A.D.1417) and this book was published again in Chungcheng Province(忠淸道) in Sejong's(世宗) 9th year(A.D.1427). The book published in Taejong's days was in the possession of books department of Kung-nae-cheng(宮內廳) in Japan and was the oldest medical book of existing ones. 2. Bang-Jung-Hyang-Yack-Mock-Cho-Bu(方中鄕藥目草部) of this book was originally intended to be adjusted in each division with the title of Bang-Jung-Hyang-Yack-Mock(方中鄕藥目). But Herb part(草部) only followed editing progress of Jeung-Lew-Bon-Cho(證類本草), the rest is not divided into each part and is together arranged at the below of Herb part with the title of Bang-Jung-Hyang-Yack-Mock-Cho-Bu. The Korean inscriptions on some drugstuffs in this book are different between Native Name(鄕名) of three volumes of provisions and general-spoken(俗云) of Bang-Jung-Hyang-Yack-Mock-Cho-Bu. In this, it is estimated that the publishing time and editor of tile volume of provisions and Bang-Jung-Hyang-Yack-Mock-Cho-Bu are different. I think Choi Ja-ha compiled this behind three volumes of provisions when he published. 3. This book picked some prescriptions which consisted of obtainable drugs with ease in Korea in the books of Chell-Keum-Yo-Bang(千金要方), Oi-Dae-Bi-Yo(外臺秘要), Tae-Peong-Sung-Hye-Bang(太平聖惠方), Ju-Hu-Bang(?後方), Kyung-Hum-Yang- Bang(經驗良方) Bo-Je-Bon-Sa-Bang(普濟本事方) Bi-Ye-Baik-Yo-Bang(備預百要方) and so on and got together our own prescriptions. On the whole Bi-Ye-Baik-Yo-Bang was a chief referrence book, On this, other books referred to and corrected. 4. In provisions quoted from Hyang-Yack-Jip-Sung-Bang(鄕藥集成方), there are seven provisions; leg-paralysis part, coughing part, headache part, obstetrics part, etc. don't show in this book. This is why Choi Ja-ha published only certain texts on Dae-jang-do-kam edition his own posession. So we can think the existing edition has a little misses compared with original edition. 5. This book recorded only names of drugstuffs in animal drug department like fowls, crab, goldbug, earthworm, etc. and didn't tell us ways of taking those. This is effect of Buddhist culture on medicine. This is efforts to practice 'Don't murder';one of Five Prohibition of Buddhism. 6. Beacause this book was published at the time, when our originative medicine would be set forth. This followed the Chinese ways in Theory, Treatment, Prescription and used 'Hyang Yack' in Medication out of theory of Korean medicine, which was a transitional form. So this is all important material which tell us aspects of development of 'Hyang Yack' the middle of Korea Dynasty.and this is also the beginning of originative, medical works like Dong-Eui-Bo-Kam(東醫寶鑑), Dong-Eui-Su-Bo-Won(東醫壽世保元). 7. There are few contents based on 'Byen-Jeung-Lon-Chi(辨證論治)'in this book. So we can see this book is not for doctors who study medical thoughts but for general public who suffer from diseases resulted from war. Because this book was written for a first-aid treatmeant, this is an index of medical service for the people those days. And this is also an useful datum for first-aid medicine or military medicine in these modern days. 8. Nowadays, parts of learned world of Korean medicine disregard essential theories and want to explain Korean medicine only by the theories or the methods o
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향약집성방(鄕藥集成方)에 나타난 삼화자향약방(三和子鄕藥方) 조문(條文)의 연원(淵源)에 대한 연구
신영일,Sheen Yeong-il 대한한의학방제학회 1997 大韓韓醫學方劑學會誌 Vol.5 No.1
Samhwaja-hyangyakbang has been known as the book of herbalogy published by the man, Samhwaja. But there are no records about the additor, and the absence of the document, it is so difficult to be informed about the time when it published and other details. But in this document and Hyangyakgugeubbang, there are similar prescriptions to Sublingual Inflammation, Aphtose, Anthrax, Furoncle, Ulcer, Dysentery, etc. So the time it published is estimated to Goryo-dynasty Gojong epoch(1232-1251) when the Hyangyakgugeubbang was published. In addition, this document seems to be basis of Hyangyakjipseongbang, Because, Hyangyakjipseongbang quoted more than 140 provisions from this document. Prescriptions that are different from other books in dosage or taking method, took those of Biyebaekyobang. In explanation or classification of disease, this document almost copied those of Biyebaekyobang, so this document take Biyebaekyobang for origin and take Sikeuisimkam, Taepyungseonghyebang, etc, for reference.
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신영일(Sheen Yeong il) 대한한의학원전학회 2017 대한한의학원전학회지 Vol.30 No.2
Objectives : 28 prescriptions with the name Dossi can be found in Yixuerumen, and all these prescriptions are highly useful due to their clinical effectiveness. Among them, Dossisosihotang has an important role as the essential prescription utilizing harmonizing and releasing formula. Therefore, this paper aims to ponder upon this prescription. Methods : Dossisosihotang s origin and effectiveness were studied, and the findings served as the basis for analyzing the varied forms of this prescription which came about in the later generations in order to consider more detailed usage of this prescription. Results & Conclusions : Dossisosihotang directs its patient to consume sosihotang added with chenpi, shaoyao, chuanxiong, then simmered, and added with three spoons worth of raw wormwood juice. Its origin can be traced back to shachechuifa s Sihossanghaeeum, and it is mainly effective for treating the blood aspect syndrome of lesser yang disease such as women s cold damage and heat entering the blood chamber. In treating the symptom of half-exterior and half-interior, taohua developed prescriptions depending on the syndrome, such as Sihijigyungtang, Sihohamhyoungtang, Samhosambacktang, Siryungtang, Sihosamultang, Sigalhaegitang, and Samhoseoggotang. These prescriptions became widely known for their clinical efficacy, leading to many later generations of clinical doctors to use them.
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육미지황탕가미방이 노화된 Senescence Accelerated Mouse(SAM) P8의 간에 미치는 영향
김정상,신영일,김희철,박민희,나창수,Kim, Jeong-Sang,Sheen, Yeong-Il,Kim, Hee-Chul,Park, Min-Hee,Na, Chang-Su 한국현미경학회 2000 Applied microscopy Vol.30 No.4
노화된 노화촉진생쥐 (senescence-accelerated mouse, SAMPB)에 육미지황탕(六味地黃湯)에 원지와 석창포를 가미한 육미지황탕가미방(六味地黃湯加味方)을 4개월간 투여한 후 항산화효능을 검증하기 위하여 간조직의 superoxide dismutase(SOD)와 catalase의 활성도 및 세포소기관의 미세구조적인 특징의 변화를 관찰하였다. 대조군은 12개월령의 SAM P8을, 실험군은 8개월령부터 4개월간 약물을 투여한 12개월령을 사용하였다. 간조직에서 MnSOD의 활성도는 노화된 12개월령의 대조군 SAM P8이 육미지황탕가미방을 4개월간 식이시킨 12개월령의 실험군 SAM P8보다 약 11% 정도 높게 나타났지만, CuZnSOD의 활성도는 실험군이 대조군보다 20% 정도 높게 나타났다. Catalase 활성도는 육미지황탕 가미방을 식이시킨 실험군이 대조군에 비하여 약 67% 높게 나타났다. 전자현미경 관찰 결과, 대조군 SAM P8의 간세포는 실험군에 비하여 과립형질내세망의 내강이 전반적으로 다소 평대되어 있었고, 사립체의 형태는 비정상적이면서 기질의 전자밀도가 높을뿐만 아니라 사립체능선이 뚜렷하지 않았다. 무과립형질내세망은 세포질 전반에 걸쳐 발달해 있었으나 그들의 내강은 다소 팽대해 있었다. 이상의 결과로 보아 육미지황탕가미방(六味地黃湯加味方)은 노화된 SAM P8의 간조직에 대하여 항산화 효능이 있을 것으로 생각된다. The aim of this study was to discover whether Yukmijihwangtang which was added Plygalae Radix, Acori graminei Rhizoma, has antioxidant effects on aged senescence-accelerated mouse (SAM) P8. The control group used 12 months old SAM P8 and the experimental group was treated with Yukmijihwangtang extracts from 8 to 12 months old. In the liver, the MnSOD of the control group were approximately 11% higher than that of the experimental group treated with herbal extracts, but CuZnSOD activities of the experimental group were approximately 20% higher than that of the control group. The catalase activities of the experimental group was approximately 67% higher than that of the control group. The hepatocytes, in the control group compared with the experimental group, contained the dilated cisternae of rough endoplasmic reticulum and the abnormal mitochondira which had electron-dense matrix and indistinguishable cristae. The inner cavity of the smooth endoplasmic reticulum were slightly dilated, and a number of vacuoles and transitional vesicles occured in of the hepatocytes of the control group. These results suggest that the herbal extract has an antioxidant effects on the liver of SAM P8.
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『상한전생집(傷寒全生集),변상한발열예(辨傷寒發熱例)』 등에 대한 연구(硏究)
최동수 ( Dong Su Choi ),신영일 ( Yeong Il Sheen ) 대한한의학원전학회(구 대한원전의사학회) 2010 대한한의학원전학회지 Vol.23 No.4
『Sanghanjeonsaengjip(傷寒全生集)』 is a classic medical work, written by the outstanding physician DoHwa(陶華)in the Ming Dynasty. The characteristic of SangHanJeonSaengJip(傷寒全生集) is that this book succeeded to the spirit of pattern identification and treatment of Treatise on Cold Damage Diseases, newly changed a table of contents by symptoms, and together with this indicated the prescriptions in accordance with diswase-pattern at YuJeungHwalInSeo(類證活人書), HwaJeGookBang(和劑局方) etc. Also because this kept the existing ephedra decoction, cinnamom twig decoction, minor decoction of bupleurum, decoction for reinforcing middle-energizer and replenishing qi etc.`s name on and unlikely indicated the medicine composition, it caused confusion, but at the later ages EuHakIpMun(醫學入門) the so-called ``Doci(陶氏)`` was added to the prescription name, so we are able to distinguish. Together with this, this book dose not indicate the dosage of medicine and indicates the first, the second, and the third classes(上中下) below medicine. As this dose not mean the three grades of quality-good, fair, and poor(上中下) of 『Shennong`s Classic of Materia Medica』 but expresses the sovereign medicinal as the first class (上), minister medicinal as the second class(中) and assistant and courier medicinal as the third class(下), doctors can voluntarily decide the dosage of medicine in accordance with the degree of disease At this thesis, I single out ten chapters in contents of 2nd volume named Hyeong(亨) corresponding to the details, among SangHanJeonSaengJip(傷寒全生集). I discussed superficial fever types of exogenous febrile disease in chapter 1, aversion to cold types of exogenous febrile disease in chapter 2, syndrome caused un-sufficient sweating in chapter 3, organic fever types of exogenous febrile disease in chapter 4, aversion to wind types of exogenous febrile disease in chapter 5, Tidal fever types of exogenous febrile disease in chapter 6, Alternative attacts of chills and fever in chapter 7, Dysphoria with smothery sensation in chapter 8, Fidgetiness of exogenous febrile disease in chapter 9, and Headache of exogenous febrile disease in chapter 10, and together with this I discussed, in detail, which influence the prescriptions which are listed on each chapter have caused on future generations In accordance with this, I think that the above-mentioned symptoms and prescriptions are important when I research cold damage and warm disease study. So I orderly research revision, annotation, rendering and an investigation.
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