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자궁근종 환자에서 측정한 혈중 bisphenol-A 농도
변재천 ( Jae Chun Byun ),한명석 ( Myoung Seok Han ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.10
목적: 비스페놀-A (Bisphenol-A, BPA)가 자궁근종 환자에서 어느 정도 검출되며, BPA가 자궁근종의 성장에 어떤 영향을 미치는지 알아보고자 하였다. 연구 방법: 총 131명의 환자가 이번 연구에 참여하였다. 우선, 101명의 자궁근종 환자를 질식초음파로 측정한 자궁근종의 크기에 따라 mild군(n=38), moderate군(n=33), severe군(n=30)으로 나누고, 자궁근종이 없는 대조군 30명을 정하여 효소면역측정법(enzyme linked immunosorbent assay)으로 BPA 수치를 측정 비교하였다. 결과: 총 131명의 환자 중 BPA가 검출된 경우는 110건으로 검출률은 83.9%였다. 대조군은 86.7%에서 검출되었고, 자궁근종군은 전체 101명 중 83.1%에서 검출되었으며, 각 군별로는 mild군 중 71.1%에서, moderate군 중 84.9%에서, 그리고 severe군 중 96.7%에서 검출되었다. 각 군의 BPA의 평균농도는 평균±표준오차로 표시하여 대조군이 0.557±0.086 ng/mL, mild군이 0.273±0.052 ng/mL, moderate군이 0.336±0.063 ng/mL, 그리고 severe군이 0.636±0.075 ng/mL로 네 군 사이에 유의한 차이가 있었다(P=0.0003). 결론: 혈중 BPA의 검출율은 대조군에서 86.7%, 그리고 자궁근종군에서 83.1%였다. 이번 연구에서 대조군과 전체 자궁근종군의 혈중 BPA 농도에는 유의한 차이를 발견할 수 없었다. 향후 BPA가 자궁근종의 성장인자로 규명되기 위해서는 BPA에 폭로될 위험이 높은 사람들을 대상으로 한 보다 밀접하고 순차적인 연구가 필요하리라 생각된다. Objective: To investigate how many leiomyoma patients are exposed to bisphenol-A (BPA) and whether the serum concentration of BPA is related to leiomyoma growth. Methods: Total 131 patients were recruited for measuring BPA. Initially, leiomyoma patients were divided into three groups, mild (n=38), moderate (n=33), and severe (n=30) according to the size of the leiomyomas. The control (n=30) group was defined as having no leiomyomas. The identification and diameter measurements of leiomyomas was performed by transvaginal ultrasonography. Serum BPA concentrations were measured by enzyme linked immunosorbent assay. Results: BPA was detected in 83.9% out of 131 samples totally, and 83.1% out of 101 leiomyoma patients. In detail, the detection rates of serum BPA were 86.7% in control group, 71.1% in mild group, 84.9% in moderate group, and 96.7% in severe group. The mean BPA concentrations in the control group was 0.557±0.086 ng/mL and those in the leiomyoma groups were 0.273±0.052 ng/mL (mild), 0.336±0.063 ng/mL (moderate), and 0.636±0.075 ng/mL (severe) (P=0.0003). Values are mean±standard error. Conclusions: The detection rate of serum BPA in control and leiomyoma groups were 86.7% and 83.1% respectively. However, there was no statistical significance of serum BPA concentrations between control and leiomyoma groups. To verify the effect of BPA on the leiomyoma growth, close and sequential monitoring for the person who have exposure risk is recommended.
변재란(BYUN, Jai-Ran) 한국영화학회 2012 영화연구 Vol.0 No.52
The study takes notice of ‘Film circumstances’ understood at a certain time that movie house in essential place for enlightment and publicity of the national policy for ordinary people when TV broadcasting is not still propagate across the country in South Korea, and then Daehan News(“Korean news”) and cultural Film provided the ordinary way of film exhibition and its contents regardless of film reception and response of audience. Particularly this work examines the military government early penertrated the importance of the film as propaganda media during the period, founded the National Film Production Center and news films and cultural films produced through this, introducing and persuading ordinary people of the state family planning programs in Korea. This shows beginning with perfect visualization of familiar-looking slogan, economical thought of population including a population explosion and data through surveys and census programs, regarding its past as the other and providing utopian vision for the future based on a dichotomy between rural and urban areas and the process making ‘the new family’ adhering closely to contradictory attitude about women and family through national strategic planning rationality.