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쥐 회전근개 파열 모델의 건 부착부에서 카토제닌 주사의 효과
김동현 ( Dong Hyun Kim ),민승기 ( Seung Gi Min ),김훈민 ( Hun-min Kim ),최진현 ( Jin-hyun Choi ),이현주 ( Hyun Joo Lee ),박경현 ( Kyeong Hyeon Park ),윤종필 ( Jong Pil Yoon ) 대한스포츠의학회 2020 대한스포츠의학회지 Vol.38 No.4
Purpose: The purpose of this study was to investigate the effects of kartogenin (KGN) on the tendon-bone interface in a rat rotator cuff tear model. Methods: Twenty male rats were divided into two equal groups; group 1 (repair only) and group 2 (KGN single injection). A rat rotator cuff rupture model was prepared, and KGN (500 μM) was injected into the repair site. The specimens were collected after 8 weeks, and biomechanical and histological analyses were performed. We assessed the healing quality of the tendon-to-bone repair site using six aspects of tendon tissue. The histological findings were classified semiquantitatively into four grades (grade 0, the poorest appearance; grade 1, poorer; grade 2, better; and grade 3, marked regeneration). Results: Group 2 showed a higher mean ultimate load to failure than the control group (group 1: 25.78±31.38 N, group 2: 55.64±36.02 N; p=0.011). On histological analysis, group 2 exhibited a significantly greater total score (group 1: 7.20±2.14, group 2: 9.50±1.84; p=0.019), collagen fiber continuity (group 1: 1.20±0.42, group 2: 1.70±0.48; p=0.024), and collagen fiber density (group 1: 1.50±0.52, group 2: 2.20±0.63; p=0.080). Metachromasia were more intense in group 2 than in the control group. Conclusion: A single injection of KGN reinforces biomechanical strength and the formation of collagen and fibrocartilage at the tendon-to-bone interface in a rat rotator cuff tear model.
김희준(Hee-June Kim),박경현(Kyeong-Hyeon Park),이현주(Hyun-Joo Lee),경희수(Hee-Soo Kyung) 대한정형외과학회 2022 대한정형외과학회지 Vol.57 No.3
연골지방종은 성숙한 연골세포와 지방조직으로 이루어진 드물게 발견되는 양성 간엽종이다. 연골지방종은 구강 내나 유방 등에서 주로 발견되는 것으로 보고되며, 슬관절에서 발견되는 경우는 극히 드문 것으로 알려져 있다. 저자들은 좌측 슬관절 전방부에 종괴를 주소로 내원한 60세 여자 환자에서 연골지방종을 경험하였고, 이에 대한 진단과 치료에 대해 문헌 고찰과 함께 보고하고자 한다. 자기공명 영상 검사상 슬개건 내측부위에 지방 성분과 석회화된 성분으로 구성된 이종의 양상을 보이는 종괴를 확인하였다. 종괴에 대해 수술적 절제를 시행하였고, 크기는 약 4.5 cm×3 cm×4 cm에 둥근 모양으로 피막에 싸여진 형태였다. 종괴의 후면에서 지방조직과 연골조직이 혼재된 양상의 형태를 보였으며, 병리 조직 소견상 성숙한 지방세포와 초자연골 조직으로 구성된 연골지방종으로 진단하였다. Chondrolipoma is a rare benign mesenchymoma containing mature cartilage and adipose tissues. Chondrolipoma has been encountered mainly in the oral cavity and breast; however, this type of mesenchymoma occurs extremely rarely in the knee area. This paper reports a case of a 60-year-old woman who presented with a two-year history of a palpable mass lesion at the anterior side of the left knee. Magnetic resonance imaging showed a mass lesion adjacent to the medial side of the patellar tendon. The mass had a heterogenous nature, consisting of fat components and calcification. Surgical excision was performed. The size of the excised mass was approximately 4.5 cm×3 cm×4 cm, and it had a round shape and was encapsulated. The posterior part of the mass had a mixed pattern comprised of fat and cartilage tissues. A pathological examination showed that the chondrolipoma was composed of mature adipose and hyaline cartilage tissues.
자세 변화와 도구 사용 시 최대 들숨과 날숨 시 호흡근의 근활성도 차이
김근조(Keun-Jo Kim),장영(Zang Rong),조동혁(Dong-hyeok Jo),정주은(Ju-eun Jeong),김경규(Gyeong-gyu Kim),김문규(Mun-kyu Kim),김민지(Min-zy Kim),김현승(Hyun-seung Kim),박경현(Kyeong-hyeon Park),박새롬(Sae-rom Park),이영준(Yeong-jun Lee) 대한심장호흡물리치료학회 2021 대한심장호흡물리치료학회지 Vol.9 No.1
Purpose : In this study, we aimed to measure how respiratory muscle activity changes as posture changes. We also aimed to measure the inspiratory sternocleidomastoid (SCM) and upper trapezius (UT) muscle activities as well as expiratory rectus abdominis (RA) and oblique abdominis (OA) muscle activities in healthy male and female university students in their twenties. Methods : Using the percentage of reference voluntary contraction (% RVC) with electromyography, we measured the SCM, UT, RA, and OA muscle activities in 16 healthy male and female university students in their 20s according to position change and breather tool use. Results : We found that the average value of inspiratory and expiratory muscle activities by posture was highest when using the breather tool. When using the tool with 10-mm and 2-mm straws for standard breathing at rest in the sitting position, a statistically significant increase in SCM, UT, and OA activities occurred (p < 0.05). For standard breathing at rest in the supine position, a statistically significant increase in SCM, RA, and OA activities occurred (p < 0.05). Conclusion : In clinical application, it may be better to use a respiratory muscle-strengthening tool to increase the activity of inspiratory and expiratory muscles.