Gold contact allergy from dental implants

( Eun Jin Doh ),( Dong Hun Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Dental implants could be suspected as a source of contact allergy to gold. Although gold compounds are commonly positive on patch testing, clinical relevance is relatively low and may be difficult to determine. A 53-year-old female reported 7-year history of burning pain with mild lichenoid ulceration of oral mucosa. Her symptoms had started shortly after change the dental implant on right lower molar. She developed erosions on right lower buccal mucosa and gum near the site where implant came into contact with. The patient underwent patch test which includes Korean standard series 25 and Dental screening series. In addition, a specimen of the patient’s own dental materials were alse tested. The final reading revealed 2+ reaction to Gold sodium thiosulfate, Nickel sulfate. And also, original plate and removed sheet from her dental prosthesis had 1+ reaction at 48hr reading. When we studied about the composition on her crown, abutment, and fixture of implant, it is revealed that her dental material contained gold. After she changed her dental materials which contain no gold, her symptom was much improved. Multiple studies have suggested that localized exposure to dental gold may result in systemic gold exposure and lead to systemic allergic contact dermatitis. It is important to note that even gold can induce contact allergy from dental materials.

P075 Prospective pilot study on combined use of pulsed dye laser and 1% topical rapamycin of cutaneous capillary malformation

( Eun Jin Doh ),( Jungyoon Ohn ),( Min Ji Kim ),( Young Gull Kim ),( Soyun Cho ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Pulsed dye laser (PDL) is considered as treatment of choice for cutaneous capillary malformation. The regeneration or revascularization of blood vessels after PDL treatment is one of the causes of treatment failures. Recently, topical administration of rapamycin (RPM) was introduced as a possible adjunctive therapeutic option to minimize post-laser revascularization in facial capillary malformations. Objectives: We evaluated the effect of combined use of 1% topical RPM with PDL compared to PDL alone in cutaneous capillary malformation of trunk or extremities and tried to identify the effective length of RPM application. Methods: The study design was a prospective side-by-side comparison of 6 patients. Three adjacent areas of cutaneous capillary malformation which had never been treated before were selected in each patient and underwent the following regimens: (A) PDL + vehicle for 8 weeks post-PDL; (B) PDL + topical RPM for 1 week post-PDL; and (C) PDL + topical RPM for 8 weeks post-PDL. Each patient was treated by PDL for two sessions with 8 weeks interval. Topical RPM was applied to the area once daily. Results: Only one of 6 patients showed clinical improvement with combined RPM treatment. Overall, there was no statistically significant difference in erythema and blanching rate among PDL alone and combined topical RPM regimens. Conclusion: In conclusion, topical RPM does not seem to be effective as a treatment modality for non-facial port wine stains.

Treatment of lower eyelid bags with transconjunctival carbon dioxide laser blepharoplasty and fat repositioning by removed fat transplantation

( Eun Jin Doh ),( Dong Hun Lee ),( Ho Joon Yoon ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: Transconjunctival blepharoplasty has been the treatment of choice for eyelid bags. To overcome untoward side effects of conventional blepharoplasty such as deepening of wrinkles and sunken eyes, we developed a revised transconjunctival blepharoplasty with fat repositioning by simultaneous liposuction and fat transplantation. Objectives: To compare efficacy and side effect profiles of transconjunctival carbon dioxide laser (CO2)-assisted blepharoplasty and the revised technique. Methods: A total of 301 Korean patients with a clinical diagnosis of lower eyelid bag who visited Budang Yemiwon Dermatologic Clinic was enrolled. Whereas 128 patients were treated with conventional blepharoplasty,173 patients undergone the revised technique. Satisfaction scale and adverse events were evaluated. Results: While conventional blepharoplasty produced high satisfaction in affected patients, with 85.9% in “excellent” and “good” improvement, more patients (89.6%) treated with the revised technique reported “excellent” and “good” outcomes albeit statistically not significant. Notably, substantial adverse events such as deepening of wrinkles, sunken eye and darkening of skin were significantly less prevalent in those treated with the revised technique than those with the conventional one. Conclusion: The revised transconjunctival CO2 laser-assisted blepharoplasty with fat repositioning is an effective and safe modality associated with more satisfaction and less long-lasting complications.

Tumoral Calcinosis as an Initial Complaint of Juvenile-Onset Amyopathic Dermatomyositis

( Eun Jin Doh ),( Jung Yoon Moon ),( Sue Shin ),( Soo Hyun Seo ),( Hyun Sun Park ),( Hyun Sun Yoon ),( So Yun Cho ) 대한피부과학회 2016 Annals of Dermatology Vol.28 No.3

Calcinosis is rarely observed in juvenile-onset amyopathic dermatomyositis in contrast to juvenile-onset dermatomyositis. A 6-year-old female presented with several 0.5 to 2 cm-sized painless grouped masses on both knees for 3 years. The patient also presented with multiple erythematous scaly patches and plaques on both elbows, knuckles, buttock, ankles and cheeks. Her mother had similar skin lesions which were erythematous scaly patches on the knuckles and elbows, since her childhood. When skin biopsy was performed from a left knee nodule, liquid chalky discharge was observed. The biopsy results were consistent with calcinosis cutis. Other biopsies from erythematous patch of the patient and erythematous patch of her mother showed vacuolization of basal cell layer with inflammatory cell infiltrations. Laboratory findings showed normal range of serum phosphorus (4.5 mg/dl), calcium (9.3 mg/dl), 1,25-dihydroxy-vitamin D (10.8 ng/ml) and parathyroid hormone levels (11 pg/ml). Both patient and her mother had no history of muscle weakness and showed normal levels of muscle-specific enzyme. Both patients were diagnosed with juvenile-onset amyopathic dermatomyositis based on histopathology and cutaneous manifestations with no evidence of muscle weakness and no serum muscle enzyme abnormalities. Tumoral calcium deposits observed in daughter was diagnosed as dystrophic calcinosis which can be rarely seen in juvenile-onset amyopathic dermatomyositis. The patient is being treated with oral acetazolamide (40 mg/kg/d) for calcinosis. (Ann Dermatol 28(3) 375∼380, 2016)

Neck rejuvenation using a multimodal approach in Asians

( Eun Jin Doh ),( Jiwon Kim ),( Dong Hun Lee ),( Je-young Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: A multimodal approach is essential for neck rejuvenation because many factors contribute to the aging of the neck. Objectives: We evaluated the effect of combined therapy using microfocused ultrasound with visualization (MFU-V), neuromodulator injection, and filler injection for neck rejuvenation. Methods: Subjects were sequentially treated with three kinds of interventions in a single session as follows: (A) MFU-V or calcium hydroxyapatite injection for restoring skin laxity; (B) hyaluronic acid filler injection for horizontal neck lines; and (C) neuromodulator injection for platysmal bands. Results: All ten patients showed clinical improvement of neck aging after combined treatment. Patients with more aged neck at baseline were more likely to show greater improvement after treatment. Conclusion: Neck rejuvenation using a multimodal approach is effective in Asians.

A questionnaire survey on understanding of atopic dermatitis among Korean patients and caregivers

( Eun Jin Doh ),( Mira Choi ),( Ji Soo Lim ),( Hyun Sun Yoon ),( Dong Hun Lee ),( Kyu Han Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: Therapeutic education is important for successful management of Atopic dermatitis (AD). Objectives: To provide effective therapeutic education, common misunderstandings and demands about AD among patients and caregivers need to be reviewed. Methods: A questionnaire survey about the course, etiology and management of AD was conducted forpatients and caregivers who visited Department of Dermatology at Seoul National University Hospital. Results: A total of 177 subjects participated in the study. Only 34.5% of subjects was aware of natural course of AD that usually improves with age. Many subjects (52.6%) misunderstood relapse of AD symptoms for development of tolerance to topical steroids. 89.3% of subjects believed that enhancement of patients’ immune system can improve the symptoms of AD. Dietary restriction is considered as an essential management strategy, and 55.4% of them agreed to postpone the beginning of weaning food. Most subjects did not haveaccurate information about cleansing. In particular, 34.3% of subjects reported that they used only water without any cleanser. 49.6% of subjects obtained informationabout AD from medical doctors, and consider them as the most reliable sources (83.5%). Subjects prefer printed materials (42.6%) to seminars or video-clips for obtaining educational contents. Conclusion: Therapeutic education about the course, etiology and management of AD with printed materials made by physicians will be valuable for the effective management of AD.

아토피피부염에 대한 올바른 교육의 중요성에 대한 설문조사

도은진 ( Eun Jin Doh ),최미라 ( Mira Choi ),임지수 ( Ji Soo Lim ),윤현선 ( Hyun-sun Yoon ),이동훈 ( Dong Hun Lee ),김규한 ( Kyu Han Kim ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.6

Background: Therapeutic education is important for successful management of atopic dermatitis (AD). Objective: To provide effective therapeutic education, clear common misunderstandings, and answer questions regarding AD among patients and caregivers. Methods: A questionnaire survey was conducted for patients and caregivers who visited the Department of Dermatology at Seoul National University Hospital, Seoul, Korea, regarding the course, etiology, and management of AD. Results: Among the 327 subjects who participated in the study, only 35.2% were aware of the natural course of AD, which usually improves with age. Many subjects (53.2%) misinterpret AD relapse as resistance to topical steroids. We found that 87.8% of subjects were under the impression that improvement in a patient`s immunity can improve the symptoms of AD. Dietary restriction was considered an essential management strategy, and 59.0% of subjects agreed to delay the initiation of weaning foods. Most subjects did not have accurate information about cleansing methods, and 30.9% of subjects reported that they used only water without any cleanser. We noted that 47.5% of subjects obtained information regarding AD from medical doctors who they considered the most reliable sources (82.5%). Subjects preferred printed materials (41.3%) over seminars or video-clips to obtain educational information. Conclusion: Therapeutic education regarding the course, etiology, and management of AD using printed materials put together by physicians would be a valuable tool for the effective management of AD. Institutional support such as educational programs covered by the National Health Insurance Service is required. (Korean J Dermatol 2017;55(6): 329∼336)

TIBA 處理가 大豆의 生育과 收量에 미치는 影響

都銀洙,梁啓鎭,金應吉 中部大學校 農業開發硏究所 1994 農業開發硏究論文集 Vol.3 No.-

無限伸育形인 無限콩과 有限伸育形인 普光콩을 試驗 材料로하여 摘芯과 TIBA(2, 3, 5-triiodobenzoic acid) 處理가 生育과 收量에 미치는 影響을 究明코자 本 試驗을 實施하였던 바 그 結果를 要約하면 다음과 같다. 摘芯과 TIBA 處理에 依하여 莖長과 主莖節數가 모두 減少되었고 減少의 폭은 無限콩이 普光콩보다 컸다. 節間長은 摘芯으로 길어졌으나 第 5葉期의 TIBA 處理에서는 7~10번째 節間長이 特히 짧아져 莖長이 단축되었다. 摘芯과 TIBA 處理는 主莖節數와 粒數를 減少시킨 반면에 分枝莢數와 粒數는 增加되었다. 收量은 普光콩에서는 增收되지 않았으나 無限콩에서는 摘芯區에서 9%, TIBA 處理區에서 13% 增收되었다. This experiment was conducted to investigate the effects of pinching off the terminal bud and TIBA(2, 3, 5-triiodobenzoic acid) on growth and yield characters of soybean. The results were summarized as follows ; Number of nodes and length of main stem were decreased by pinching and TIBA and degree of reduction was larger for Muhankong, a Indeterminate variety, than Bokwangkong, a determinate variety. Internode length was increased by pinching, but decreased by TIBA treatment. Especially, the lengths of the 7th~l0th internodes were decreased significantly by TIBA at V_6 stage. Numbers of pods and seeds on main stem were decreased, but numbers of pods and of seeds on branches were increased by pinching and TIBA treatment. Yield was not affected by pinching and TIBA in Bokwangkong, but soybean yield was increased by pinching and TIBA treatment, 9% and 13%, respectively, in Muhankong.

An association between attention deficit hyperactivity disorder and diet

Eun-Jung Kim,Ho-Jang Kwon,Mina Ha,Ki-Chung Paik,Myung-Ho Lim,Seung-Jin Yoo,Jin-Ah Doh,Jae-Wha Kim,Yearn-Mi Yi,Sun-Ae Choo 환경독성보건학회 2009 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

Isolation and characterization of a Oszinc626, RING-H2 zinc-finger Protein Gene in AclDs Mutant Lines of Rice (Oryza sativar L.)

Doh Won Yun,Hyeon So Ji,Yong Hwan Park,Moo Young Eun,Seok Cheol Suh,Myung Chul Lee,Seul Ah Park,Yu Jin Jung,Byung Ohg Ahn 한국육종학회 2008 한국육종학회 학술발표회 발표요지 Vol.40 No.1