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최장윤,권영삼,장광호,박세일 한국임상수의학회 2010 한국임상수의학회지 Vol.27 No.6
The purpose of this experiment was to study the effects of demineralized bone matrix (DBM), calcium sulfate (CS), and calcium metaphosphate (CMP) on osteogenesis of unicortical 5-mm-diameter defects in canine femurs. Seventy-two femoral unicortical defects of nine adult beagles (eighteen femurs, four unicortical femoral defects were made in each femur) were made. Three bone graft substitutive materials such as CS, DBM, and CMP and the empty controls were compared each other. The postimplanted specimens were harvested at week 4, 8, and 24 for radiographic,biochemical and histomorphologic evaluation. In radiograph, CS group appeared to be absorbed rapidly and made new cortical bone. Defects of cortical bone was gradually filled with new bone around bone graft materials in DBM group. Bone graft substitutes weren't absorbed rapidly but, remained performing structural roles in cortical bone after 24 weeks in CMP group. Radiographic intensity of control group showed significantly (p < 0.05) lower compared to that of experimental group. Defects treated with either CS, DBM or CMP had more bone formation than the untreated defects (p < 0.05). The results of analysis in the cortical bone region were deduced the conclusions as follows. Three bone graft materials seemed to accelerate the formation of new bone compared with controls for 24 weeks. CMP group having more or less large particle space was more adequate than DBM group, as well as more compact CS group was more pertinent than CMP group as the glues for bones.
Pediatric follicular lymphoma of the parotid gland
최장윤,최혁준,임광일,권호,변준희,정성노 대한두개안면성형외과학회 2018 Archives of Craniofacial Surgery Vol.19 No.4
Primary malignant lymphoma rarely presents as a mass in the salivary gland. It accounts for about 1% of salivary gland tumors. The lymphomas of the parotid gland are mainly non-Hodgkin’s lymphoma of B-cell follicular type. It usually occurs in male adults and is very rare in children. In contrast to the intractable disease course of adult parotid follicular lymphoma, when occurred in children or adolescent, its prognosis is very good when it is first treated with surgical excision. Thus, a solitary follicular lymphoma in an extranodal site that has occurred in children is termed separately as pediatric follicular lymphoma (PFL). We share our treatment experience of a 16-year-old PFL patient through surgical removal combined with superficial parotidectomy. In line with the few previous case reports of PFL, we suggest that active surgical removal should be undertaken for solitary, extranodal follicular lymphoma of the pediatric and adolescent population.
개에서 제3안검 제거 후 전기소작법을 이용한 누점폐쇄 효과
최장윤,박현정,이주명 한국임상수의학회 2006 한국임상수의학회지 Vol.23 No.1
To evaluate the effect of punctal occlusion on tear preservation after third eyelid resection, 10 eyes wereoperated in dogs and observed changes in tear preservaperformed on five healthy dogs with no clinical sings of ocular irritation and no history of dry eye syndrome. TheST was performed for 10 days before surgery, and on the day 0, 1, 3, 5, 7, 9, 11, 13, 17, 21, 25, and 30 afterthird eyelid resection. The mean STT was 17.4±0.15 mm/min(mean±SEM) for 10 days before surgery. And, it was11.5±0.55 m/min for 30 days after surgery in puntal occlusion(PO) group. The mean ST was 17.3±0.32 mm/minfor 10 days before surgery. And, it was more decreased to 6.5±0.60 m/min for 30 days after surgery in controlgroup. The paired t-test was performed. Mean ST after the third eyelid resection was higher in PO group than thatof control throughout experimental period (p<0.05). In summary, the effect of thermal punctal occlusion significantlyincreased on the tear preservation by 28.86±7.96%. These results suggest that application of thermal punctal occulsionin dry eye syndrome will promote tear preservation.
Jack Fruit 잎으로 부터 Glucosyltransferase Inhibitor 물질의 분리 및 구조
안봉전,최장윤,권익부,니시오카 이트슈,최정 ( B . J . An,J . Y . Choi,I . B . Kwon,I . Nishioka,C . Choi ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.4
In the course of our studies on the development of anti-plaque agents for prevent of dental caries, we investigated the effect of some of polyphenolic compounds on the glucosyltransferase from Streptococcus mutans. The structure revealed that the main anti-plaque components of jack fruit extract were (+)-catechin, procyanidin B-3, afzelechin-(4α→8)-catechin and procyanidin C-1. Procyanidin C-1 was the most active component and this compound inhibited on glucosyltransferase noncompetitively.