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대한간학회지 제8차 춘계학술대회 초록집 : 포스터 전시 ; 심한 범혈구 감소증을 동반한 간경변증 환자의 거대비장 치료로서 경정맥 문맥단락술(TIPS)의 효과
김현지 ( Kim Hyeon Ji ),김성준 ( Kim Seong Jun ),신원창 ( Sin Won Chang ),이진호 ( Lee Jin Ho ),최원충 ( Choe Won Chung ),김관엽 ( Kim Gwan Yeob ),김영훈 ( Kim Yeong Hun ) 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.2(S)
만성 신부전 환자에서 Catecholamine 의 제거율
이은주(Eun Joo Lee),위경소(Kyoung So Wee),최태승(Tae Seung Choe),차대룡(Dae Ryong Cha),조원용(Won Yong Cho),김형규(Hyoung Kyu Kim),김형건(Hyoung Gun Kim),최원충(Won Chung Choi) 대한내과학회 1989 대한내과학회지 Vol.37 No.5
N/A The adrenergic system interacts with a vaiety of tissues and organs, including the kidney. However, there is little known about the renal clearance of catecholamine (CAs) in man. To obtain this information, 4 normal subjects and 6 patients with chronic renal failure (CRF) were studied. Plasma and urinary CAs concentrations were measured by high performance liquid chromatography with an electrochemical detector. Plasma CAs concentrations (pg/ml) were norepinephrine (NE) 44.62±83.29 (pg/ml) end DOPAC 585.58±462.47 in normal subjets, and NE 632.20±290.40 and DOPAC 990.55±69.05 in CRF. Plasma CAs concentrations of the CRF group were higher than those of normal subjects, but did not differ significantly among the groups (p<0.05). Urinary CAs excretion amounts were NE 59.3±34.9 (pg/ml), E 11.9±10.2. DOPAC 27.l±61.4, and dopamine 13.4±11.2 in normal subjects, and NE 100.0±90.1, E 135.5±147.4, DOPAC 401.7±500.7, and dopamine 163.9±115, 7 in CRF. Urinary CAs and CAs clearance levels were lower in the CRF group than in normal subjects, but did not differ significantly between the groups. It is concluded that a chronic reduction in excretory kidney function may have no relevant impact on circulatory levels of CA per se, although their urinary excretion falls distinctly at the stage of advanced renal failure. These aspects deserve consideration when pathogenetic or diagnostic studies of catecholamines are performed in normotensive or hypertensive patients with impaired kidney function.