합리적 행위이론 기반 예비간호사의 신종감염병 환자 간호의도 영향요인

정선혜,송영숙 기본간호학회 2024 기본간호학회지 Vol.31 No.1

Purpose: The aim of this study was to identify the factors affecting graduate nurses’ intention to care for emerginginfectious disease patients based on the theory of rational action. Methods: The participants were 127 graduatenurses who had graduated from in Gyeongsangbuk Province. Data were collected from March 25 to April 1, 2022. Descriptive statistics, the t-test, analysis of variance, the Scheffé test, Pearson correlation coefficients, andstepwise multiple regression analysis were used for data analysis. Results: The mean scores for attitudes,subjective norms, and nursing intention for patients with emerging infectious diseases were 30.60±5.49, 30.17±6.38, and 69.19±8.97, respectively. Nursing intention was significantly different according to major satisfaction(t=-3.02, p=.003) and the presence of medical personnel in the family (t=2.30, p=.023). Nursing intention had asignificant positive correlation with attitudes (r=.44, p<.001) and subjective norms (r=.37, p<.001). The variablesthat significantly affected nursing intention were attitudes (β=.42, p<.001), satisfaction with the nursing major(β=.21, p=.008), and the presence of medical personnel in the family (β=.17, p=.026), with a total explanatory powerof approximately 26%. Conclusion: The findings of this study suggest that the development and application ofprograms on positively changing attitudes toward patients with emerging infectious diseases and increasingsatisfaction with the nursing major are needed.

유방암에서 18F-Fluorodeoxyglucose (FDG) 섭취도에 영향을 미치는 요인들

정선혜,이은혜,박정미,이혜경,이범하,최나미 대한영상의학회 2010 대한영상의학회지 Vol.63 No.3

목적: 유방암의 18F-Fluorodeoxyglucose (FDG) 섭취도에 영향을 미치는 요인들을 알아보고자 하였다. 대상과 방법: 2006년 4월부터 3년간 본원에서 positron emission tomography/computed tomography (PET/CT)를 시행한 유방암환자 180명(평균나이, 48세)의 187개 병변을 대상으로 하였다. PET/CT는 이중 검출기가 장착된 장비(Biograph2, Siemens)를 이용하였다. 최대 표준섭취계수(peak standardized uptake value, 이하 pSUV)와 조직학적 유형(n=187), 등급(n=142), 병변의 크기(n=153)간의 관계를 분석하였다. 결과: 조직학적 유형은 침습관상피암 156개, 관상피내암 10개, 유두암과 점액암 각각 6개, 침습소엽암 4개, 수질암 3개였으며, 그밖에 화생성암, 신경내분비암이 각각 1개였다. 조직학적 유형에 따라 pSUV에 차이가 있었다(p < 0.005). 등급을 알 수 있었던 침습관상피암 142개는 1등급 25개, 2등급 66개, 3등급 51개였으며 침습관상피암의 등급이 높을수록 pSUV가 높았다(rho=0.41, p < 0.001). 전반적으로 유방암의 조직학적 유형에 관계없이 병변이 클수록 pSUV가 높았다(rho=0.525, p < 0.001). 침습관상피암은 저등급에서는 크기가 클수록 pSUV가 높았지만(rho=0.48-0.86, p < 0.001) 고등급에서는 크기와 pSUV 사이에 상관관계를 보이지 않았다(p > 0.001). 결론: 유방암의 조직학적 유형에 상관없이 병변이 클수록 pSUV가 높았다. 침습관상피암은 등급이 높을수록 pSUV가 높았다. 저등급 침습관상피암에서는 병변이 클수록 pSUV가 높았으나 고등급은 크기와 pSUV간에 상관관계가 없었다. Purpose: To evaluate factors affecting 18F-Fluorodeoxyglucose (FDG) uptake in breast cancer. Materials and Methods: For 3 years from 2006, 180 patients (mean age 48-years-old) with 187 breast cancers underwent positron emission tomography-computed tomography (PET/CT; biograph2, Siemens) at our institute and were enrolled in this study. We evaluated whether there was a correlation between the peak standardized uptake value (pSUV) of PET/CT and the histologic type of the breast cancers (n=187), grade of the invasive ductal cancers (n=142), and tumor size (n=153). Results: The different histologic types of breast cancers include IDCs (n=156), in situ ductal carcinoma (n=10), papillary cancer (n=6), mucinous cancer (n=6), invasive lobular cancer (n=4), medullary cancer (n=3), metaplastic cancer (n=1), and neuroendocrine cancer (n=1). pSUV showed significant differences according to histologic type (p<0.005). For the available cases (n=142), IDCs were classified as grade 1 (n=25), grade 2 (n=66), and grade 3 (n=51) and correlated with the histologic grade of IDCs (rho=0.41, p<0.001). pSUV was correlated with tumor size regardless of histologic type (rho=0.525, p<0.001). In low grade IDCs, pSUV was correlated with tumor size (rho=0.48-0.86, p<0.001), but not in high grade IDCs (p>0.001). Conclusion: Regardless of histologic type, the larger the breast cancer, the higher the pSUV; in addition, the higher the grade of IDCs, the higher the pSUV. For the low grade IDCs, pSUV is correlated with tumor size; however, this is not the case in high grade IDCs.

특집원고 : 우리시대의 연기 교육방법론 ; 스타니슬랍스키 신체행동법 및 행동분석법의 운용

정선혜 한국연극교육학회 2005 연극교육연구 Vol.11 No.-

普遍性에서 多聲樂의 하모니로

鄭善惠 한국아동문학학회 2000 한국아동문학연구 Vol.- No.8

페미니스트 관점으로 본 『주홍글자』 영한번역 양상

정선혜,박윤희 동국대학교 동서사상연구소 2020 철학·사상·문화 Vol.0 No.34

본 연구는 가부장제 글쓰기에 나타나는 왜곡된 여성상을 바로 잡고자 하는 페미니즘 번역이론에 근거하여 여성 관련 이슈에 관한 영한 소설번역에서의 번역 양상을 살펴보고, 파생 가능한 문제들에 대해 논한다. 이를 위해 페미니스트 번역의 관점에서 페미니즘 주제를 다룬 나다니엘 호손(Nathaniel Hawthorne)의 『주홍글자』(The Scarlet Letter)를 선정하여, 다수의 영한 번역본을 페미니즘 관점에서 비교 분석하고, 이를 바탕으로 향후 영한 소설번역의 바람직한 번역 방향을 가늠하고자 한다. Based on the feminist translation theory, which aims to correct the distorted female images appearing in patriarchal writings, this study examines the translation aspects in English-Korean novel translation on women-related issues and discusses the derived problems. To this end, we select Nathaniel Hawthorne's The Scarlet Letter, which deals with the subject of feminism, to compare and analyze a number of English-Korean translations from the perspective of feminism. Seven translated texts in Korean are analyzed to figure out to what extent feminist translation strategies were used in them. Based on this, we measure the desirable direction of translation of English-Korean novel translations.

LIN28B confers radio-resistance through the posttranscriptional control of KRAS

정선혜,우홍균,Woong-Yang Park 생화학분자생물학회 2009 Experimental and molecular medicine Vol.41 No.12

To screen the differentially expressed microRNAs related to radio-resistance, we compared the microRNA profiles of lung cancer cells with different responses to ionizing radiation (IR). Of 328 microRNAs in microarray, 27 microRNAs were differentially expressed in NCI-H460 (H460) and NCI-H1299 (H1299) cells. Among them, let-7g was down-regulated in radio-resistant H1299 cells, and the level of let-7g was higher in radio- sensitive cells like Caski, H460, and ME180 in qRT-PCR analysis than in radio-resistant cells like A549, H1299, DLD1, and HeLa. Over-expression of let-7g in H1299 cells could suppress the translation of KRAS, and increase the sensitivity to IR. When we knockdown the expression of LIN28B, an upstream regulator of let-7g, the level of mature let-7g was increased in H1299 cells and the sensitivity to IR was also enhanced in LIN28B knockdown cells. From these data, we suggest that LIN28B plays an important role in radiation responses of lung cancer cells through inhibiting let-7g processing and increasing translation of KRAS.

本質을 향한 探照燈

鄭善惠 한국아동문학학회 2001 한국아동문학연구 Vol.- No.9

回復의 文學

鄭善惠 한국아동문학학회 2000 한국아동문학연구 Vol.- No.8

Duodenal Metastasis of Pulmonary Pleomorphic Carcinoma: A Case Report

정선혜,백상현,이남석,고은석,신화균,차장규,박재성 대한영상의학회 2016 대한영상의학회지 Vol.74 No.2

Pulmonary pleomorphic carcinoma is an uncommon malignant lesion of the lung. A chest radiograph of 53-year-old man who was suffering from a cough revealed a well-defined mass-like opacity with a broad base on the pleura at the apico-posterior segment of the right upper lobe of the lung. The subsequent chest computed tomography (CT) scan demonstrated an inhomogeneous enhancing mass with central low-attenuation in the right upper lobe. A lobectomy was performed and the mass was determined to be a pleomorphic carcinoma with visceral pleura invasion. Forty days after the operation, the patient complained of melena and an abdominal CT revealed an intraluminal and extraluminal protruding mass around the prepyloric antrum and duodenal bulb. The mass was removed by en-block surgery and diagnosed as metastatic pleomorphic carcinoma from the lung. Previous articles reported a median survival time of 3–10 months for pleomorphic carcinoma, but in this case, the patient has continued to survive, 11 years after surgery. Chest and abdominal CTs have revealed no evidence of tumor recurrence or metastasis.

Covid 19 이후 만성콩팥병 환자에서의 가소제 노출 수준 파악

정선혜,박나연,이정환,이정표,고영림 한국환경보건학회 2022 한국환경보건학회 학술대회 자료집 Vol.2022 No.5