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정기헌 대한건선학회 2019 대한건선학회지 Vol.16 No.1
The human body is colonized by millions of microbiome. Continuous cross-talk between microbiome and immune system plays an essential role in host homeostasis. Dysbiosis (change in microbial diversity and community composition) is associated with many chronic inflammatory diseases, including psoriasis. Psoriasis is an immune-mediated chronic inflammatory disease. Although its pathogenesis is not fully understood, it is hypothesized to be multi-factorial, influenced by genetic and environmental factors. Recently, skin and intestinal microbiota have been gaining attention for the pathogenesis of psoriasis. However, microbiome studies remain controversial due to conflicting study results. The skin microbiota plays a crucial role in maintaining integrity and function in critically exposed barrier. Modification of the composition of skin microbiota could affect the local T cell subsets and local inflammation but does not seem to affect distant sites. The gut microbiota provides essential health benefits to the host, particularly by maintaining intestinal mucosal barrier and normal immune function. Interestingly, the intestinal microbiota is able to affect systemic immune system and distant sites, such as skin, joint, liver, nervous and cardiovascular systems. The microbial imbalance in gut could affect development of Th17 cells, increase of gut permeability, bacterial translocation, and inflammation. Further studies of functional, metabolic, and immunological impact of microbial communities in psoriasis are needed.
전기차 발열 유리의 기능 신뢰성 확보를 위한 3레그 2상 인버터의 허용제어
정기헌,이형우,이교범 대한전기학회 2023 전기학회논문지 Vol.72 No.7
This paper proposes a fault tolerance control method for a three-leg two-phase inverter to secure the functional reliability of xEV components. It diagnoses an open-switch fault with the size of the current sensed within 2 cycles in real time without applying conventional coordinate conversion and complex formulas. The MOSFET that has failed stops operating, and another MOSFET in the same leg are set to always conduct. In the three-leg two-phase inverter, the fault state is classified for each case in which an open-switch fault diagnosis has occurred, and the duty ratio of the A, B, and C phases is adjusted. Through duty ratio adjustment and phase shift control for each switch of the inverter, functional reliability is secured by supplying the same power as before the failure. The functional reliability of an inverter is verified through simulations and experimental result.