Effects of Antioxidants on the Gamma-Radiation Damage of the Cultured Vascular Smooth Mucle Cells of Rat Aorta

이종도,최형철,강영진,김명세,이광윤 대한약리학회 2007 The Korean Journal of Physiology & Pharmacology Vol.11 No.5

To study the protective effects of antioxidants on the radiation damages of the cells, vascular smooth muscle cells (VSMC) from thoracic aorta of Sprague-Dawley rats were cultured and irradiated with gamma-ray. Cell viability was measured by direct cell counting and MTT assay, and flow cytometry was performed to measure fractional distributions of the cells. Gamma-ray irradiation inhibited cell proliferations accompanied with decreased G1 phase and increased S- and G2/M phases, and the maximum effects were observed at 1500 or 2000 cGy. Submaximal concentrations of antioxidants, such as allopurinol, vitamin C, N-acetylcycteine (NAC), lipoic acid, dihydrolipoic acid and rebamipide tended to increase the cell viability suppressed by low dose of radiation (500 cGy), and enalapril and vitamin E increased it significantly. Allopurinol, vitamin E, NAC, lipoic acid, captopril and enalapril significantly increased G1 phase. Allopurinol and vitamin E tended to increase c-Myc expression, detected by Western blot, that was reduced by the radiation, and enalapril increased it significantly. The cell viability and c-Myc expression were highly correlated (r=0.97) with each other. These results suggest that antioxidants, especially enalapril and vitamin E, recover the viability of VSMC from gamma-radiation injury, through a mechanism which includes increase of c-Myc protein expression.

Associations of Lifestyle Factors with Cancer Mortality and Life Expectancy in Men

이종도,강호율 한국웰니스학회 2013 한국웰니스학회지 Vol.8 No.4

ined the combined effects of these risk factors on the most common cancer mortality (top 10 leading cancers) in men. This was a prospective cohort study using data from 24,723 men (aged 20-80 years). We classified a low-risk profile as never smoked, moderate or high fitness, and normal waist girth, and further categorized them as 0, 1, 2, or 3 combined low-risk factors. During an average of 14.5 years of follow-up (358,055 person-years), there were 244 most common cancer deaths. Cox proportional hazards regression was used to examine the association between the number of low-risk factors and the 10 leading cancer mortality in men. After adjustment for multiple risk factors, men who were physically fit, never smoked, and had a normal waist girth had a 73% lower risk of the 10 leading cancer mortality (95% confidence interval [CI], 56%-83%) compared with men with zero low-risk factors. Men who maintained these three low-risk factors had an 8 year (95% CI: 5.4-11.0) longer life expectancy as compared with men with none of these low-risk factors. Approximately 53% (95% CI, 37%-64%) of the 10 leading cancer deaths might have been avoided if the men had maintained these 3 low-risk factors. Maintaining a normal waist girth, being fit, and never smoking is associated with lower risk of the most common cancer mortality in men.

보건계열학과와 비보건계열학과 학생들의 구강위생지식 및 관리 실태

이종도,신두만,박종탁 대한치과기공학회 2012 대한치과기공학회지 Vol.34 No.4

치과(齒科) 이용실태(利用實態)및 행동의식(行動意識)에 관(關)한 연구(硏究)

이종도,Lee, Jong-Do 대한치과기공학회 2003 대한치과기공학회지 Vol.25 No.1

The purpose of this study is to examine the effect of parents knowledge on oral health status toward their children. This study was carried out to investigate and analyze the cognitive degree of dental subjects and general public who have an experience to be treated for their dental knowledge, operative dentistry, and dental prothesis in the oral health care through the questionnaires. The results are as follows : 1 : In questioning the frequency in the visitation of dental clinic, 68.8% usually go to see dentists, if children's teeth have trouble. It was the reason that economical standard and educational level were enhanced as before. 57.6% took a kind of medical measures. 2 : In surveying the preference of dentists’ age or gender, 56.9% preferred younger dentists to older or female dentists. On the contrary, 56.9% children want younger dentists, and 64.8% children want female dentist doctor. As a conclusion, the preference of dentists’ age or gender is relevant with a view to remove big horror, which can be evoked by dental measures. 3 : In questioning the possession amount of decayed teeth, 45.8% have more than four. Usually those parents who have children filled their decayed teeth with artificial or installed with dental prosthesis. As a conclusion, age is relevant in this study in p<0.05 level. 4 : In asking for efficient starting-year of tooth brushing, 42.6% said that 2 or 3 year age is the most efficient, and especially 80.6% teach children to learn brushing themselves. (P<0.05). As a conclusion, the voluntary brushing can be good behaviour for good dental health. 5 : In surveying the way they obtained dental information, 38.9% were given form mass media, but 90% were once not delivered with the education of dental health. Because parents have been known narrow and deficient information of dental health through mass media, experts in dental health have to deliver help their parents to be delivered with systematical dental information. The conclusion of this study can be summarized that parents' role is very important to their children's tooth health and the education program for systematical dental information should be delivered to their parents.

한국의 過消費형태 : 미시분석

李鍾都 서울여자대학교 사회과학연구소 1997 사회과학논총 Vol.3 No.-

過消費는 매스콤에 나타나는 인기용어일 뿐만 아니라 식자층에도 隨炙되는 센세이션날한 용어이다. 그러나 경제학적 분석을 통해 보면, 그 용어가 타당한지 그러고 그 용어가 정확한 의미가 무엇인지를 이해하는 것은 쉬운 일이 아니다. 本研究의 목적은 1989년 소비형태 그러고 그 이후 韓國國民의 소비형태를 過消費로 매도하는 것에 대해 이 時期의 소비행위를 어떻게 이해할 것인가를 분석하는데 있다. 巨視經濟年間 資料 및 都市家計의 微視的 年間資料를 이용해, 1989년이후 소비행태의 특징을 분석한다. 本究는 茸證分析을 통해 1989년 이후 韓國소비행태의 특징이 네가지로 요약될 수 있다는 것을 보여주고 있다 첫째, 금융자산의 급격한 증가는 소비자의 유동성 제약을 크게 완화시켰다. 둘째, 소득의 급격한 증가가 금융자산의 유동성 제약의 완화와 결합되어 소비증가가 가속화 되었다‘ 세째, 이러한 효과는 금융자산의 효과를 무시한 한게소비성향을 상승시켜 소득증가 보다 소비가 더 증가한 현상을 초래하게 되었다, 이러한 현상을 우리 사회전체의 매스콤, 식자층 및 정부 정책당국은 過消費로 묘사했다. 네째, 韓國의 소비형태를 분석하는 동태적 최적면형은 소비자의 流動性制約을 고려하는 것이어야 한다. 그러나 소비형태를 분석하기 위한 ‘표본집단에서는 본류가 아닌 (outlier)’ 저소득층의 소비증가 및 고소득층의 高價外製品의 수요증대는 過消費로 매도할 것이 아니라 그 근원을 이해하는 미시적 분석이 동윈되어야 한다.

인력수급 대책을 위한 치과기공사의 보건지소 진출에 관한 연구 - 2012년 틀니보험화 정책을 중심으로 -

이종도,김정숙,박광식,Lee, Jong-Do,Kim, Jeong-Sook,Park, Kwang-Sig 대한치과기공학회 2010 대한치과기공학회지 Vol.32 No.4

Purpose: This study evaluated the manpower planning of dental technicians. Methods: Methods : Survey was conducted regarding subject's general characteristics, characteristics of dental technician's occupational view and working conditions, and reason to enter into branches of the public health enter. The survey sample consisted of 323 dental technicians (221 male/ 102 female). Survey was conducted for one month from August 1 to September 1 in 2010. Following results were obtained. Results: 1. Regarding general characteristics of the subjects, there was a slight male predilection with 68.4%. Subjects in their 40s occupied the highest proportion of 32.2%. Majority of subjects worked in the big cities (71.5%). Favored working places were dental laboratory (57.6%) and dental hospital or dental clinic (19.5%). Although no position is available in the public sector such as public health center or health care civil servant, 9.3% preferred working in the public health center. Public sector is more favored than 2-year technical colleges or dental supply and equipment companies. In respect to education, 57% of the subjects graduated college. 67.8% were married. Subjects who specialize in the porcelain or all-ceramic were 57.9%. With regard to current position, head of the dental laboratory was most common. 2. Following occupation characteristics were found. Economic reason took the highest proportion when deciding their occupation (39.9%) followed by gaining social experience (36.5%). Majority of the subjects (76.5%) wanted to work as dental technicians until their retirement. 71.5% pursuit to become a manager of the dental laboratory. 76.1% agreed on opening a dental technician position in the public health center. Regarding an authority to lead developing the dental technician position in the public sector, majority of the subject chose ministry of health and welfare (35.6%) and Korean dental technologist association (34.7%). Employment (average, 30%) and turnover rate (average, 36.5%) of dental technology college graduates ranged from 40% to 60%. Most important factors for the employment were practical experience (41.2%) and competency (34.4%). With regard to job satisfaction, so-so as 46.7% and satisfactory was 42.7% 3. In respect to the reason for opening a position in the public health center, 'It is needed to continue denture rogram for elderly patients' obtained the highest score (4.14 point). 'Institutional devices are required to open a position for dental technicians as a public healthcare provider' received high score (4.11 point). 4. Concerning the working conditions, 'professional knowledge is required' received the highest score (4.23) followed by 'too short maternity and parental leave' (4.21). 5. Relationship between general characteristics of the subjects and favor of working in the public health center was investigated. Significant differences were found according to the current and favored working area, favored occupation, education level, marital status, and specialty. Working in the public health center was favored by following subjects: working in mid- or small-sized cities (4.16 point, p<0.05); PhD degree-holder (4.59 point, p<0.01). 6. Among general characteristics of the subjects, significant difference of working conditions was found in the following factors: gender; working areas; favored working areas; favored working positions, and education level. Majority of subjects favored working in big cities and currently work in big cities although satisfaction was comparatively low (3.75 score). 7. Future plan to work in public health center was evaluated according to occupational characteristics. Subject's intention to work in the public healthcare center was significantly affected by opening of dental technician position, leading authority, average turnover rate, and factors affecting employment. Working in the public health care center was favored by the following subjects: Dental technicians who actively suppo

폭력의 대위법 : Machbeth 시론(試論)

이종도 연세대학교 1998 원우론집 Vol.27 No.1

子女에 대한 口腔 保健 基礎 知識에 관한 硏究 - 大邱市內 齒科內院 患者의 父母를 中心으로 -

李鍾道 대한치과기공학회 1997 대한치과기공학회지 Vol.19 No.1

금융의 세계화와 한국의 대응

李鍾都 서울여자대학교 사회과학연구소 2003 사회과학논총 Vol.9 No.-

외환위기 이후 자본시장의 빠른 개방으로 한국의 금융변수와 국제금융센터의 변수 사이의 상관계수가 외환위기 이전 보다 훨씬 더 크게 증가하였다. 한국의 금융시장 및 금융기관도 국제금융시장으로 통합이 가속화되어 가고 있다. 이러한 변화는 미국 클린턴 대통령 시절의 ‘워싱턴합의’가 금융 세계화를 가속화시키는 계기가 된다. 그 주요 내용은 세계 최강 미국 금융산업의 절대적 비교우위를 전세계 시장을 대상으로 경쟁할 수 있는 틀을 마련하기 위한 소위 금융시장의 범세계화이다. 그러나 금융의 세계화 속에서도 각국의 경제발전정도, 문화, 및 제도상 차이가 존재하기 때문에, 각국에 알맞은 금융시장 및 금융제도가 이루어질 수 있도록 해야 한다. 이를 반영하려면, 그 나라의 흡수능력에 맞는 금융의 세계화가 필요하다는 것을 인식해야 한다. 한국은 금융 세계화의 흡수능력을 평가하고 이를 지속적으로 발전시키는 노력이 필요하다.

자녀(子女)에 대한 구강(口腔) 보건(保健) 기초(基礎) 지식(知識)에 관한 연구(硏究) (대구시내(大邱市內) 치과내원(齒科內院) 환자(患者)의 부모(父母)를 중심(中心)으로)

이종도,Lee, Jong-Do 대한치과기공학회 1997 대한치과기공학회지 Vol.19 No.1

The purpose of this study is to examine the effect of parents knowledge on oral health status toward their children. This study was carried out to investigate and analyze the congnitive degree of dental subjects and public who have an experience to be treated for their teeth on the dental knowledge, operative dentistry, and dental prothesis in the oral health care through the questionnaires. The results are as follows; 1. In questioning the fundamental knowledges, 47.6% of respondents in their thirties said that milk tooth of their children are number 20. Although schooling level of their parents is not rel evant to this survey, 21.9% who have only high-school diploma, said also "number 20". As a conclusion, most parents have a big concern in their children's teeth. 2. 44.0% parents answered, asked "who do decayed teeth sping up, and 26.4% said" It is why children eat sugary. Asked "What is efficient preventive measures decayed teeth", 26.5% said it is very relevant to be in the utilization of F-tooth-paste. 3. For children's good theeth, periodically brushing is the important. Most parents recognized brushing efficient. 4. In questioning the possession amount of decayed teeth, 45.8% have more than four. Usually those parents who have children filled their decayed teeth with artificial or installed with dental prosthesis. As a conclusion age is relevant in this study in P<0.05 level. 5. In asking for efficient starting-year of tooth brushing, 42.6% said that 2 or 3 year age is the most efficient, and especially 80.6% teath children to learn brushing themselves(P<0.05) 6. In surveying the way they obtained dental information, 38.9% were given from mass media, but 90% were once not delivered with the education of dental health. Because parents have been know narrow and deficient information of dental health mass media, experts in dental health have to deliver help their parents to be delivered with systematical dental information. The conclustion of this study can summarized that parent's role very important to their children's tooth health and the education program for systematical dental information should be delivered to their parents.