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2P-479 Field effect transistor를 이용한 열전현상에 의한 ZnO nanoparticles의 계면에서의 carrier이동에 대한 연구
윤태준,박병남 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1
열전 현상은 온도구배에 의한 carrier의 확산이라는 단순한 현상이지만, 이 현상을 통해 carrier의 이동 특성에 대한 다양한 특성을 관찰할 수 있다. Carrier의 이동 특성을 관찰하기 위해서는 carrier의 이동을 조절할 수 있는 Field Effect Transistor (FET)를 이용할 수 있다. 이 실험에서는 Ultra Violet (UV)을 조사하여 carrier concentration을 변화하는 ZnO nanoparticles의 성질을 이용하여 계면에서의 carrier이동 특성을 FET를 이용하여 관찰하였다.
윤태준,안성수,표정윤,송정식,박용범,이상원 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.11
Purpose: We investigated whether serum clusterin levels could reflect the current antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)-specific indices. Materials and Methods: Fifty-seven patients with AAV and 40 healthy controls were included in this study. AAV-specific indices included the Short-Form 36-Item Health Survey Physical and Mental Component Summaries (SF-36 PCS and MCS) scores, Birmingham vasculitis activity score (BVAS), five-factor score (FFS), and vasculitis damage index. Clinical and laboratory data and AAV-specific indices were obtained at blood collection. The highest tertile of BVAS (≥16) was defined as high activity of AAV. Results: The median age of AAV patients was 64.0 years and 19 patients were male. SF-36 PCS score (r=0.328), SF-36 MCS score (r=0.289), BVAS (r=-0.404), erythrocyte sedimentation rate (r=-0.336), and C-reactive protein levels (r=-0.421) were significantly correlated with serum clusterin levels. In the multivariable linear regression analysis using AAV-specific indices and serum clusterin levels, both FFS (β=0.412) and serum clusterin levels (β=-0.250) were significantly associated with BVAS. When the optimal serum clusterin cut-off level for high activity of AAV was identified as 130.45 μg/mL, patients with serum clusterin level ≤130.45μg/mL had a significantly higher risk for high activity of AAV than did those without (relative risk 7.194). Patients with AAV exhibited significantly lower serum clusterin levels than did healthy controls (168.2 μg/mL vs. 230.5 μg/mL). Conclusion: Serum clusterin levels could reflect the current disease activity in patients with AAV.
윤태준,안성수,송정식,박용범,이상원 연세대학교의과대학 2020 Yonsei medical journal Vol.61 No.8
Lectin-like oxidized low-density lipoprotein (LDL) receptor 1 (LOX1) binds to oxidized LDL, which is associated with inflammationin various vascular disorders. Here, we aimed to investigate the potential of soluble LOX1 (sLOX1) as an indicator of antineutrophilcytoplasmic antibody-associated vasculitis (AAV) activity. Serum levels of sLOX1 in frozen samples from patients withAAV enrolled in a prospective observational cohort study at the Severance Hospital were measured using enzyme-linked immunosorbentassay. Clinical and laboratory data were collected on the date when the blood sampling was performed. The associationbetween sLOX1 and clinical and laboratory data was assessed using Pearson’s correlation analysis. The median age of the recruited79 patients was 62.0 years, and 27 (34.2%) patients were men. The median Birmingham vasculitis activity score (BVAS),five-factor score, vasculitis damage index, and sLOX1 level were 6, 1, 3, and 911.9 pg/mL, respectively. Correlation analysis basedon BVAS revealed that sLOX1 and total cholesterol were significantly inversely correlated with BVAS (r=-0.224, p=0.047 and r=-0.424, p<0.001, respectively). No significant correlations were observed between continuous variables and sLOX1 except forBVAS, although total cholesterol tended to correlate with sLOX1 (r=0.190, p=0.093). Additionally, sLOX1 was not influenced by sex,hypertension, diabetes mellitus, or the presence of pulmonary, cardiovascular, and renal involvement of AAV. In summary, sLOX1was inversely correlated with BVAS in AAV patients, which is different from other vascular diseases or inflammatory diseases.
지역사회 보행환경에 영향을 미치는 아파트 단지 특성에 관한 기초적 연구 - 보행 거리 증가를 유발하는 아파트 단지의 규모 분석을 중심으로
윤태준,이도훈,박현수 한국문화공간건축학회 2016 한국문화공간건축학회논문집 Vol.- No.54
The purpose of this study is to analyze the influence of the development scale of the apartment complexes to the pedestrian environment for the local residents. The conflicts between the apartment block and its neighbours are occurred recently because of the increased control of the neighbours’ entries into the apartment complex. Therefore this study analyzes the relation between scale of the apartment complex and the length of the neighbours’ detour route. The results of this study are as follows: Firstly, the length increment of walking route and disenfranchised pedestrian right are the important cause of conflict. In addition, the minimum route length and detour degree arousing conflict are 456m and 1.5 degree. Secondly, there are clear positive correlations between the scale of the apartment complex and the length of the neighbours’ detour route. Thirdly, the length of the border in-between the destination facility and the apartment block is important cause of detour.