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도심에 거주하는 남성 노인에 있어서 유산소 운동능력이 혈관내 염증수치와 동맥경직도에 미치는 영향
안기만(Ki man Ahn),김윤신(Yoon shin Kim),박원하(Won Hah Park) 한양대학교 고령사회연구원 2012 한양고령사회논집 Vol.3 No.1
Experimental epidemiology and clinical studies have provided strong evidence that physical exercise has beneficial effects on multiple physiological variables affecting cardiovascular health. Cardiopulmonary function has been previously associated with atherosclerotic disease and coronary events. The aim of this study was to examine the higher levels of cardiopulmonary function are associated with lower levels of hs-CRP(high sensitive C reactive protein) and baPWV(barcahial ankle pulse wave velocity) in Korean elderly men. Study participants were 115 elderly men (mean age 62.5±2.2) participated in the research. Age, body mass index(BMI), resting heart rate, blood pressure, medical history, lipid profile, high sensitivity C-reactive protein(hs-CRP), Brachial-ankle pulse wave velocity (ba-PWV), cardiopulmonary function were measured. VO2peak higher elderly man had a significantly decreased hsCRP(0.22±0.26, p<0.05) and PWV (1439.1±159.9, p<0.05). In addition, HDL-C(55.2±14.2, p<0.05) levels was significantly increased and LDL-C(1193±21.7, p<0.05) level was decreased. This study show that VO2peak levels are positively correlated with hsCRP, HDL-C and PWV. Apparently healthy subjects with increased inflammatory markers have increased systemic arterial stiffness, which might reflect early atherosclerotic changes. Higher physical conditioning status, indexed by VO2peak, was associated with reduced arterial stiffness and hsCRP and increased HDL-C. The results of our study suggest that high cardiopulmonary function reduces hsCRP levels and improves PWV, HDL-C in Korea elderly men. 심혈관질환은 현재 선진 산업 국가들에서 성인 사망 제 1원인으로 알려져 있다. 심혈관질환에 의한 사망률은 나이가 증가하면서 더 높아지는 것으로 보고되고 있다. 이러한 심혈관질환을 일으키는 위험인자로는 나이, 신체활동의 부족, C반응성 단백(CRP), 혈관경직도(baPWV) 등이 심혈관질환을 높이는 것으로 보고되고 있다. 무엇보다 인구의 고령화로 인해 심혈관질환이 증가하고 있다는 것이다. 심혈관질환을 예방하기 위해서는 생활 습관 개선이 중요하며 그 중에서도 신체활동은 매우 중요하다. 하지만 고령의 건강한 남성을 대상으로 심폐기능과 관상동맥질환의 위험인자와의 관련성을 살펴본 연구는 부족하다. 따라서 본 연구는 60세 이상의 건강한 노인 남성(62.5±2.2)을 대상으로 심폐체력의 수준에 따른 혈중 C반응성 단백(CRP), 혈관경직도(baPWV)의 변화를 알아보고자 했다. 심장병 증상이 없는 노인 남성 115명을 대상으로 하였으며, 심폐기능 측정을 위해 운동부하검사를 실시했다. 혈액검사를 통해 혈중 CRP와 동맥경직도를 평가하기위해 baPWV 검사를 실시하였다. 그 결과 혈중 CRP는 심폐기능이 높은 그룹에서 0.22±0.26로 심폐기능이 낮은 그룹의 0.49±0.49 보다 유의하게 낮은 것으로 나타났다(p<0.05). baPWV역시 심폐기능이 높은 그룹에서 1439.1±159.9로 심폐기능이 낮은 그룹의 1523.7±236.1보다 낮게 나타났다(p<0.05). 따라서 건강한 노인 남성의 경우 심페기능이 좋은 그룹에서 심혈관질환 위험인자인 CRP와 baPWV가 유의하게 낮은 것으로 나타났다.
건강한 중년남성에 있어 유산소 운동능력(VO₂ peak)이 맥파속도(Pulse wave velocity)와 CRP에 미치는 영향
안기만(Ahn, Ki-Man),김종혁(Kim, Jong-Hyuck) 한국체육과학회 2012 한국체육과학회지 Vol.21 No.1
The purpose of this study was to effect of the aerobic capacity on arterial stiffness and CRP in healthy adults. Experimental, epidemiologic and clinical studies have provided strong evidence that physical exercise has beneficial effects on multiple physiological variables affecting cardiovascular health. The subjects consisted 699 middle aged men who was aged 40-59 years were checked by blood test(including CRP), measurement of body fat, blood pressure, exercise stress testing and pulse wave velocity. Aerobic capacity was determined in all individuals by measurement of maximal oxygen consumption during treadmill exercise. VO₂peak significantly higher man was decreased hsCRP-0.1l4㎎/ℓ(p<0.002), PWV Right side-0.160(p<0.0001), PWV Left side-0.166(p<0.0001) and increased HDL-C levels 0.205(p<0.0001). These VO₂peak associated increases in HDL-C and decreased CRP levels and PWV. This study show that VO₂peak levels are positively correlated with hsCRP, HDL-C and PWV. Apparently healthy subjects with increased inflammatory markers have increased systemic arterial stiffness, which might reflect early atherosclerotic changes. Higher physical conditioning status, indexed by VO₂peak was associated with reduced arterial stiffness and hsCRP and increased HDL-C. The results of our study suggest that high aerobic capacity reduce hsCRP levels and improve PWV, HDL-C in healthy adult man.
FRP 쉬트와 GSP로 보강된 RC 슬래브의 유효휨강성 평가
안기만 ( Ahn Ki-man ),김태완 ( Kim Tae-wan ),김광수 ( Kim Kwang-soo ),박선규 ( Park Sun-kyu ),이영재 ( Lee Young-jae ) 한국구조물진단유지관리공학회 2007 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.11 No.1
Recently, an improved capacity for RC bridges is required by their deterioration or necessary to traffic increase. Strengthening is known as a better way to improve capecity of bridges than reconstructing. Fiber Reinforced Plastics (FRP) is introduced as one of the best strengthening structures in this paper. Structures strengthened FRP are satisfied the strengthening capacity and serviceability. Therefore, FRP sheet and Glass Fiber-Steel Composite Plate (GSP) in this research were used in strengthening slab of RC bridges.. Experimental data From the Strengthening will be helpful to better understand the effect of the strengthening and effective flexural rigidity.
FRP 쉬트와 GSP로 보강된 RC 슬래브의 유효휨강성 평가
안기만(Ahn Ki-Man),김태완(Kim Tae-wan),김광수(Kim Kwang-Soo),박선규(Park Sun-Kyu),이영재(Lee Young-Jae) 한국구조물진단유지관리학회 2007 한국구조물진단학회 학술발표회논문집 Vol.11 No.1
Recently, an improved capacity for RC bridges is required by their deterioration or necessary to traffic increase. Strengthening is known as a better way to improve capecity of bridges than reconstructing. Fiber Reinforced Plastics(FRP) is introduced as one of the best strengthening structures in this paper. Structures strengthened FRP are satisfied the strengthening capacity and serviceability. Therefore, FRP sheet and Glass Fiber-Steel Composite Plate(GSP) in this research were used in strengthening slab of RC bridges. Experimental data From the Strengthening will be helpful to better understand the effect of the strengthening and effective flexural rigidity.
제2형 당뇨환자의 유산소능력과 말초동맥혈관기능, CRP(C-reactive protein)와의 관계
안기만(Ki-Man Ahn),김윤신(Yoon-Sin Kim),김종혁(Jong-Hyuck Kim) 한국생활환경학회 2012 한국생활환경학회지 Vol.19 No.2
The purpose of this study was to investigate the effect of aerobic capacity (VO₂peak) would ameliorate inflammatory, anti-inflammatory markers and vascular function in patients with type 2 DM. To compare the importance of different inflammatory markers and traditional risk factors in predicting peripheral vascular disease(PAD) in patients with Type 2 diabetes mellitus. Diabetes mellitus (DM), chronic inflammation and vascular function are strongly related to increased cardiovascular risk. The purpose of this study was to evaluate whether an aerobic capacity (VO₂peak) would ameliorate inflammatory, anti-inflammatory markers and vascular function in patients with type 2 DM. The subjects consisted 203 middle aged men who was aged 40-59 years were checked by blood test(including CRP), measurement of body fat, blood pressure, lipid profile, exercise stress testing and ABI. Aerobic capacity was determined in all individuals by measurement of maximal oxygen consumption during treadmill exercise. Control group VO₂peak were significantly high compared with type 2 diabetes mellitus patients group(p=0.01). This study show that VO₂peak levels are positively correlated with hsCRP (r=0.22) and ABI(ABI_R, r=0.137, ABI_L, r=0.86) in patient with type 2 diabetes mellitus. Higher physical conditioning status, indexed by VO₂peak was associated with reduced arterial stiffness. The results of our study suggest that high aerobic exercise capacity was associated with reduced arterial stiffness in type 2 diabetes mellitus.