http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
인슐린 비의존형 당뇨병 환자에서 MTHFR 유전자 다형성과 당뇨병성 합병증과의 관계
신종성(Jong Sung Shin),오광식(Kwang Sik Oh),권순길(Soon Kil Kwon),지정훈(Jeong Hoon Ji),이태원(Tae Won Lee),박영선(Young Sun Park),김미성(Mi Sung Kim),궁성수(Seong Su Koong),오태근(Tae Geun Oh) 대한내과학회 2001 대한내과학회지 Vol.61 No.4
N/A Background: Diabetic nephropathy develops in 20-30% of patients with non-insulin dependent diabetes mellitus (NIDDM). Poor glycemic control, hypertension and duration of diabetes are known as risk fact ors for the development of diabetic nephropathy and there is high prevalence of diabetic nephropathy in the patients who have familial history of diabetic nephropathy, so it has been assumed that genetic fact or is associated with the background of its occurrences. Recently it has been observed that a cytosine to thymidine substitution of the methylenetetrahydrofolate reductase (MTHFR) gene at nucleotide 677 (C677T) was related to diabetic nephropathy in patients with NIDDM and MTHFR gene polymorphism was also known to predispose to vascular disease. This study was performed to investigate whether MTHFR gene polymorphism is associated with the development of diabetic nephropathy and macrovascular disease in NIDDM patients. Methods: The study population consisted of 243 NIDDM patients (duration≥10 years). Nephropathy was defined by 24 hour urinary protein excretion of more than 500 mg. The MTHFR gene fragment was extracted using the polymerase chain reaction. The presence of the mutation was identified by HinfI digestion, which cuts at the mutation site, followed by 2.5% metaphore agarose electrophoresis and ethidium bromide staining. Statistical differences in genotype distribution and allele frequencies among the groups were assessed by the chi-square test. Results: There was no difference in clinical characteristics except the prevalence of hypertension and diabetic retinopathy between nephropathy group and non-nephropathy group. The data do not show any difference of genotype distribution or allele frequencies between patients with or without diabetic nephropathy and macrovascular disease Conclusion: With the above results, it is assumed that there are no significant relationships among MTHFR gene polymorphism, diabetic nephropathy, and macrovascular disease. (Korean J Med 61:391-398, 2001)
신종성(Shin Jung Sung),한병선(Han Byung sun) 한국사진지리학회 1998 한국사진지리학회지 Vol.9 No.1
Large city is one of the most important destination of tourist across the world. With a large population, facilities such as museums, shops, theatres and sports have been developed to a high standard for local people and these would have drown visitors from at least the wider region. More and more many cities saw the tourist industry as one which should be encouraged. The aim of this study is to examine, the direction of urban tourism development of Seoul. The results of this study are as follows: Firstly, it is necessary to move toward balancing the tradition, present and natural nature. Secondly, it is necessary to make city having a lots to see and do. Thirdly, it is necessary to make convenient transportation system in order to connect tourist with tourist attractions. Fourthly, it is necessary to make well-maintained accommodation facilities. Fifthly, it is necessary to move toward making city to give psychological stability to tourist. Sixthly, it is necessary to make landmark-being-city in order to give tourist a strong impression.
최영득,신종성,정우식,최형기,하종식,박영요 이화여자대학교 생명과학연구소 1995 생명과학연구논문집 Vol.6 No.-
SS-cream is a complex mixture containing 9 oriental herbs for treating the premature ejaculation, which is based on the traditional chinese royal herb remedy. Clinically SS-cream has been effective in the treatment of premature ejaculation and in some patients, potentiating effect of their erectile capacity was noted probably due to its combined activity of several vasoactive priciples. Therefore, we investigated the pharmacological action of SS-cream in the isolated rabbit corporal smooth muscle. Strips of rabbit corpus cavernosum were isolated and mounted in 10ml organ chambers to measure isometric tension. Muscle strips treated with increasing concentrations of SS-cream(0.05mg/ml to 0.3mg/ml) showed initial rapid contraction followed by slow gradual relaxation. Muscle strips submaximally precontracted with phenylephrine(PHE:5×10^-6M) and treated with increasing concentrations of SS-cream(from 0.05mg/ml to 0.2mg/ml) showed also initial rapid contraction above the precontracted level and thereafter, relaxed to the basal level at the dose larger than 2mg/ml of SS-cream. Relaxations of muscle strips to SS-cream were not inhibited even partially by endothelial disruption or by pretreatment with pyrogallol or methylene blue. Pretreatment of muscle strips with SS-cream caused concentration dependent inhibition of PHE(5×10^-6M) induced contraction. With these results we can conclude that SS-cream has dual action, initial rapid contractile effect which is mediated by adrenergic alpha receptor simulation, and delayed nonspecific relaxing effect which is not mediated by EDRF or nitric oxide.
XML / JAVA를 이용한 상품 카달로그 시스템 구현
이경호,신종성,박두순 순천향대학교 부설 산업기술연구소 2002 순천향 산업기술연구소논문집 Vol.8 No.1
A catalog system is defined as an electronic commerce entity that provides a common web-based storefront to a group of merchants. Customers access the "catalog system" web site to browse catalogs of merchant companies that deliver goods and services. This enables customers to search for goods, compare prices at a central location instead of visiting multiple dislocated web sites. The catalog system model is attractive to small business for which the benefits of maintaining an individual web site may never justify the overhead. The catalog system maintains a database containing catalog information for each merchant. A existing catalog system don's have a standard catalog system. This paper presents an implementation model, that uses Extensible Markup Language(XML) and JAVA to overcome the standard problem. We propose goods catalog system with XML, and JAVA.