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신재훈,이상민,이변우 한국토양비료학회 2015 한국토양비료학회지 Vol.48 No.6
Management of renewable organic resources is important in attaining the sustainability of agricultural production. However, nutrient management with organic resources is more complex than fertilization with chemical fertilizer because the composition of the organic input or the environmental condition will influence organic matter decomposition and nutrient release. One of the most effective methods for estimating nutrient release from organic amendment is the use of N mineralization models. The present study aimed at parameterizing N mineralization models for a number of organic amendments being used as a nutrient source for crop production. Laboratory incubation experiment was conducted in aerobic condition. N mineralization was investigated for nineteen organic amendments in sandy soil and clay soil at 20°C, 25°C, and 30°C. N mineralization was facilitated at higher temperature condition. Negative correlation was observed between mineralized N and C:N ratio of organic amendments. N mineralization process was slower in clay soil than in sandy soil and this was mainly due to the delayed nitrification. The single and the double exponential models were used to estimate N mineralization of the organic amendments. N mineralization potential Np and mineralization rate k were estimated in different temperature and soil conditions. Estimated Np ranged from 28.8 to 228.1 and k from 0.0066 to 0.6932. The double exponential model showed better prediction of N mineralization compared with the single exponential model, particularly for organic amendments with high C:N ratio. It is expected that the model parameters estimated based on the incubation experiment could be used to design nutrient management planning in environment-friendly agriculture.
신재훈,안난희,이상민,옥정훈,이변우 한국토양비료학회 2016 한국토양비료학회지 Vol.49 No.6
Understanding N mineralization dynamics in soil is essential for efficient nutrient management. An anaerobic incubation experiment was conducted to examine N mineralization potential and N mineralization rate of the organic amendments with different C:N ratio in paddy soil. Inorganic N in the soil sample was measured periodically under three temperature conditions (20°C, 25°C, 30°C) for 90 days. N mineralization was accelerated as the temperature rises by approximately 10% °C-1 in average. Negative correlation (R2 = 0.707) was observed between soil inorganic N and C:N ratio, while total organic carbon extract (R2 = 0.947) and microbial biomass C (R2 = 0.824) in the soil were positively related to C:N ratio. Single exponential model was applied for quantitative evaluation of N mineralization process. Model parameter for N mineralization rate, k, increased in proportion to temperature. N mineralization potential, Np, was very different depending on C:N ratio of organic input. Np value decreased as C:N ratio increased, ranged from 74.3 mg kg-1 in a low C:N ratio (12.0 in hairy vetch) to 15.1 mg kg-1 in a high C:N ratio (78.2 in rice straw). This result indicated that the amount of inorganic N available for crop uptake can be predicted by temperature and C:N ratio of organic amendment. Consequently, it is suggested that the amount of organic fertilizer application in paddy soil would be determined based on temperature observations and C:N ratio, which represent the decomposition characteristics of organic amendments.
고압 액상 크로마토그래피를 이용한 혈중 성장홀몬-결합단백 측정에 대한 초기보고
신재훈 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.4
A technique high pressure liquid chromatography (HPLC) gel filtration was used to evaluate GH-binding proteins in human serum. Seurm (75 l) was well seperated from free Biotin-hGH(PeakIII). Elution profile was monitored in potical density multisaner system. In chromatography, the molecular weight of Peak I and II appeared about 200 K and 60 K dalton respectively. In control serum, the specific binding of biotin-HGH to Peak II-BP was 59.7+/-0.8% of the optical density. Specific binding of Biotin hGH to Peak Ii-BP was low during the infant period and progressively increase as age. Using gel filltration system, binding of biotin-hGH by normal adult serum was dependent on time (maximum equlibrium was reached in 24h at 4C), temperature( 4C>22C>37C)and seurm concentration. These data indicated that human sera contain a specific binding protein for hGH. The biological significance of this binding protein remains to be investigated. We sugest the measurement of GH-BP II activity by HPLC provides a clear seperation. Our nonradioactive optical detection method by multiscaner was also highly resolution (J Kor Soc Endocrinol 8: 432438, 1993)
A sinonasal yolk sac tumor in an adult
신재훈,김지희,정경천,조경자 대한병리학회 2022 Journal of Pathology and Translational Medicine Vol.56 No.3
Yolk sac tumors (YSTs), which are also called endodermal sinus tumors, are malignant tumors of germ cell origin. These tumors usually occur in the gonads, but 20% of cases have been reported at extragonadal sites. The head and neck is a rarely affected region that accounts for just 1% of all malignant tumors of germ cell origin. In addition, YSTs arise mostly in childhood. We present a rare pathologically pure case of primary adult YST in the sinonasal area. A 45-year-old male patient presented with a rapidly growing mass in the nasal cavity, which caused nasal obstruction and bloody post-nasal drip. The histopathologic features indicated pure YST, and immunohistochemical analysis revealed positive reactivity for Sal-like protein 4 and alpha-fetoprotein. Herein, we discuss the clinical, radiologic, and histologic features of this YST and review other cases of sinonasal YST in adults.
메트헤모글로빈혈증을 보인 indoxacarb 중독 1례
신재훈,이재광,박성수,나상준,박준석,Shin, Jae-Hoon,Lee, Jae-Kwang,Park, Seong-Soo,Na, Sang-Jun,Park, Joon-Seok 대한임상독성학회 2006 대한임상독성학회지 Vol.4 No.2
Acute methemoglobinemia is induced by various causes, especially ingestion of oxidizing agents such as phenazopyridine, dapsone, and nitrite. Indoxacarb is an oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. It is known to block voltage-gated Na+ channels in insects and mammals, but the mechanism is not yet well understood. We describe a case of a 41-year-old woman with methemoglobinemia that developed following Indoxacarb ingestion, which improved after intravenous injection of methylene blue. This is the first known such case. If signs and symptoms of methemoglobinemia occur after Indoxacarb ingestion, antidotal therapy with methylene blue should be considered as a necessary treatment.