원발성 월경통 환자에 대한 Piroxicam(Feldene^� dispersible tablet)의 사용 효과

배국환 최신의학사 1986 最新醫學 Vol.29 No.6

Krukenberg 종양 11 예에 대한 임상적 고찰

배국환,한광수,박정실,배임철,이환우,박재홍 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.6

저자들은 1988년 1월부터 1997년 12월까지 만 10년 동안 부산 메리놀병원 산부인과에 난소종양으로 진단되어 수술 후 병리학적 검사 결과 krukenberg 종양으로 진단받은 11예의 환자에서 다음과 같은 결과를 얻었다. 1. 발생 빈도는 전체 난소종양 중 2.06%, 난소의 악성 종양 중 8.66%였다. 2. 환자의 연령은 26∼65세 사이에 고른 분포를 보이 며 평균 연령은 46.5세이었다. 3. 가장 흔한 증상은 복부 종괴였고 다음으로 복부팽 만, 상부 위통증, 복부 통증, 변비, 빈뇨, 부정자궁출혈의 순이었다. 4. 복수는 11예 중 10예에서 존재하였으며 그 양은 소량에서부터 5,000 ml 이상인 경우까지 다양하였다. 양 측성이 6예, 일측성은 우측이 3예, 좌측이 2예 있었다. 난소의 크기는 장지름이 6∼15 cm인 경우가 8예로 가장 많았으나 각 예마다 아주 다양하였다. 원발성 병소는 위 암이 10예, 대장암이 1예였다. 5. 평균 생존 기간은 7.68개월이었다. 1) cisplantin을 포함한 복합항암요법으로 치료한 예의 평균 생존 기간이 12.9개월, cisplantin을 포함하지 않은 화학요법에서는 4개월의 평균 생존 기간을 보였다. 2) 전자궁적출술과 양측 부속기 절제술은 14.7개월, 조직생검만 시행한 경우에는 2.5개월의 생존기간을 나 타내었다. 3) 원발 병소를 먼저 수술한 경우 평균 생존 기간이 10.5개월, 원발 병소를 수술하지 못한 경우는 3.4개월의 평균 생존 기간을 나타내었다. 4) 1예(38개월 생존)를 제외한 9예에서 12개월 이내 에 사망하였고 1예는 현재 생존하여 수술 후 11개월째 로 복합항암요법으로 추적 관리중에 있다. 이상의 결과로 저자들은 위암으로 진단된 여성의 경 우 난소에 대한 정밀검사가 중요하고, 수술중 동결절편 에서 전이성 난소암이 확인된 경우는 전자궁적출술과 양측 부속기절제술을 시행하고 원발병소의 제거와 수술 후 cisplantin을 포함한 복합항암화학요법이 필요하다고 사료된다. We reviewed 11 cases of Krukenberg tumors which had been treated at the department of Obstetrics & Gynecology, in the Maryknoll Hospital from January 1988 to December 1997. Eleven Krukenberg tumors among 127 cases of ovarian cancers were found in the hospital records for a 10 year period. The results obtained were as follows: 1. The incidence of Krukenberg tumor was 2.06% among all ovarian tumors (533 cases) and 8.66% among malignant ovarian tumors (127 cases). 2. The age of the patients ranged from 26 to 65 years, and the mean age was 46.5 years. 3. The most common symptom was palpable abdominal mass, followed by abdominal pain with distension, epigastric pain, and other gastrointestinal symptoms. 4. Among 11 cases of Krukenberg tumor, 10 cases had ascites, but the volume of ascites was variable. Bilateral involvement was shown in 6 cases and unilateral involvement in 5 cases. The size of the tumors were variable. The primary sites of these tumors were the stomach in 10 cases and the colon in 1 case. 5. The mean survival period for 11 patients was 7.68 months. (1) The mean survival period of the patients who had been treated with a cisplatin based chemotherapy regimen was 12.9 months, that of the patients who had been treated with a non-cisplantin based regimen was 4 months. (2) The mean survival period of the patients who had total abdominal hysterectomy with bilateral oophorectomy was 14.7 months, and the survival period of the patient who had only ovarian biopsy was 2.5 months. (3) When the operation for a primary lesion was performed, the mean survival period was 10.5 months but the mean survival period was 3.4 months without an operation. (4) Nine patients died within 1 year and one patient died after 38 months. One woman is still alive for 11 months. In conclusion, we think that the further evaluation of the ovary is necessary in stomach cancer of the women. In view of this, we conclude that it would seem worthwhile to consider removal of the primary lesioin case of metastatic cancer and furthermore, postoperative cisplantin based combination chemotherapy are necessary.

2004 지방재정 혁신과 향후 과제

배국환 한국지방재정공제회 2004 지방재정 Vol.2004 No.6

쌍태아 중 무두무심태아 1 례

배국환,김은주,정주섭,김상국,이환우 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.1

Acardic twining is a rare congenital anomaly, usually in monozygotic twins. This condition is characterized by the absence or rudimentary development of fetal hear, and associated with various anomaly(especially with anecephalus). The acardiac malformations are uniformly fatal in the affected twin, and mortality in the co-twin is as high as 55%. We recently experienced a case of acardius acephalus associated with a normal term male infant, so present with a brief review of the literature.

발표논문 : 행정학 교육,연구 공동체의 미래와 정책 재창조 ; 최근재정개혁과 향후과제

배국환 한국정책학회 2007 한국정책학회 학술대회 Vol.2007 No.3

기능장애성 자궁출혈의 임상 및 병리학적 고찰

배국환,부문현,김성배,동가진 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.8

1989년 1월부터 1991년 12월까지 본 병원 산부인과에서 기능장애성 자궁출혈 환자 139례 대한 임상 및 병리학적 검사에서 다음과 같은 결과를 얻었다. 1. 연령분포는 40대에서 49%, 30대, 50대 순이었고, 평균연령은 41.5세였다. 2. 사과력은 평균 임신횟수가 5.2회였고, 분만횟수는 2,3회였다. 3. 출혈양상은 월경간 출혈이 59례(42.4%), 월경과다가 42례(30.2%)로 많은 빈도를 차지하였다. 4. 자궁내막의 조직학적 소견은 중식기 내막이 54.7% 분비기 내막이 30.2%, 내막중식증이 5.7%순으로 나타났다. 5. 표준화한 월경주기 14일후 자궁내막생검을 시행한 83례중 무배란성 출혈을 보이는 경우가 71% 로 나타났다. Dysfunctional uterine bleeding(DUB)is defined as abnormal bleeding from the uterine endometrium, whic is unrelated to anatomic lesion. According to definition, dysfunctional uterine bleeding seems to be a exclusive term. The problem of abnormal uterine bleeding is the most frequent problem of all gynecologic disease and may ovvur on any age, from menarch to menopause, but occurs more frequently especially on puberty and menopause. it may occur in an ovulatory cycle, although it is more comonly associated with and anovulatory one. 139 cases of dysfunctional uterine bleeding were evaluated on clincal and pathologic aspects, and we performed brief review of literature. The results were as follows: 1. Age distribution of DUB was localized mainly in 30 ∼ 40 years, mean age was 41.5 years. 2. Dysfunctional uterine bleeding patients were mainly multigravidas (mean gravidities ; 5.2 times, mean parities; 2.6 times). 3. Among various bleeding patterns, intermenstrual bleeding was the most common pattern (42%) and the next was menorrhagia (30%). 4. Histologic findings of endometrium were proliferative phases, 76 cases (55%), secretory phase, 42 cases (30%), and hyperplasia, 8 cases (6%) in order of prequency. 5. According to endometrial biopsy, the incidence of anovulatory DUB was 71% (59 cases out of 83 cases) and ovulatory DUB was 29% (24 cases out of 83 cases).

임신 23 주의 흔적자궁 자연파열 1 예

배국환,김동옥,신근식,김용진,양화윤 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.4

저자들은 임신 23주의 흔적자궁 자연파열 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. A case of rupture of rudimentary uterine horn with 23 weeks gestation was experienced at the department of obstetrics and gynecology of Maryknoll hospital, is presented with a brief review about literature on the female genital anomalies.

최근 재정개혁과 향후과제

배국환 한국행정학회 2007 한국행정학회 학술발표논문집 Vol.2007 No.-

산전 초음파로 진단된 태반혈관종 1 례

배국환,김은주,정주섭,김상국,배임철 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.9

Benign chorioangioma of the placenta is the most common primary tumor of the placenta followed by the hydatidiform mole and choriocarcinoma. Only two nontrophoblastic primary placental tumors are known to occur: The relatively common chorioangioma, and the extremely rare teratoma. Most chorioangioma are small and only detected by careful sectioning of the placenta. Large, externally visible chorioangioma, although uncommon, may result in both maternal and fetal complications. The incidence of chorioangioma is still an unsettled issue varying between one in 3,500 and one in 9,000 placentas because of overlooking at examination of the placenta. Large tumors more than 4 cm in diameter are clinically important. The maternal complication of polyhydramnios, preeclampsia, and premature labor are those described in the chorioangioma syndrome. The neonatal complications include microangiopathic anemia, thrombocytopenia, hymolysis, low birth weight, and neonatal death. In this respect, the importance of ultrasound in the diagnosis of placental chorioangioma has now been recognized. In this paper, a case of large chorioangioma in a viable pregnancy, associated with hydroamnios, preterm labor, is presented with the brief review of the literature related to this type of tumor.

질 평활근종 1 례

배국환,한광수,박근식,손성대,김상국 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.3

저자들은 46세 여성에서 질 전벽에 발생한 평활근종 1례를 경험하였기에 간단한 문헌 고찰과 함께 이를 보고하는 바이다. The leiomyoma of the vagina is a rare benign tumor. It consists of both fibrous and muscle elements. The most frequent location is the anterior vaginal wall. Recently we experienced a case of vaginal leiomyoma arising in the anterior vaginal wall and now we present it with a brief review of the case and its literature.