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백반증 조직 이식술 치료 성적에 대한 분석: 11년간의 단일 기관 후향적 연구
노원석 ( Won Seok Roh ),박중원 ( Jungwon Park ),박수진 ( Sujin Park ),오상호 ( Sang Ho Oh ) 대한피부과학회 2022 대한피부과학회지 Vol.60 No.2
Background: Vitiligo is an acquired depigmentary disorder characterized by the destruction of melanocytes via an autoimmune-mediated process. Treatments can be categorized into nonsurgical and surgical methods. Prognostic factors of surgical management in vitiligo have not been widely studied in the Korean population. Objective: To investigate the prognostic factors of tissue grafts in vitiligo. Methods: We retrospectively analyzed patients who underwent tissue grafting for vitiligo between January 2010 and December 2020. Medical records and clinical photographs were reviewed, and demographics, disease characteristics, and treatment outcomes were collected. Results: A total of 195 cases were evaluated, and among them, 86 (44.1%) showed 75% improvement, and 49 (25.1%) showed 50% to 74% improvements 3 months after surgery. Statistical analyses showed that the prognosis of tissue grafting was significantly different according to vitiligo subtype, recipient site, and grafting method. The focal and segmental type, head and neck sites, and suction blister grafting showed favorable results compared with the non-segmental type, sites other than the head and neck, and punch grafting. Age and adjuvant phototherapy did not affect the clinical outcomes. Conclusion: This study proposes several clinical factors that affect the outcomes of skin grafting in vitiligo. (Korean J Dermatol 2022;60(2):82∼90)
김경엽,김종호,이현경,김하영,문보연,이유란,박중원,소병재,배유찬,Kim, Gyeongyeob,Kim, Jongho,Lee, Hyunkyoung,Kim, Ha-Young,Moon, Bo-Youn,Lee, Yu-Ran,Park, Jungwon,So, Byungjae,Bae, Youchan 대한수의학회 2022 大韓獸醫學會誌 Vol.62 No.1
This paper describes a fatal case of pneumonia in a 14-day-old dog caused by extraintestinal pathogenic Escherichia coli (ExPEC). The necropsy showed that almost all of left lobes of the lungs had dark-red consolidation. A histopathology examination revealed moderate acute fibrino-hemorrhagic necrotizing pneumonia with intralesional bacterial colonies. Non-suppurative epicarditis, congestion in the liver, and necrosis in the white pulp of the spleen also were found. E. coli with cytotoxic necrotizing factor 1 and α-hemolysin was isolated from the lung. This case was confirmed to have fatal pneumonia caused by ExPEC that led to a systemic infection.