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      • 馬에서의 日本腦炎에 對한 血淸學的인 調査硏究

        문희주,김승곤,장기봉,이시영 최신의학사 1974 最新醫學 Vol.17 No.2

        Prevalence of Japanese Encephalitis antibody among 242 healthy horses was assayed by means of hemagglutination inhibition test. During the pre-epidemic season in 1973, this serological survey using sera collected at the turf in Seoul. Korea inported from Australia, Japan and U. S. A. was done by age and by imported years. The obtained results are as follows; 1. Among 242 horse sera, 41 specimens had H-I positive titers and antibody posses rate is 16.9%. 2. Antibody posses rate by inported years are as follows; 1966-1967……77.8% (7/9) 1999-1970……35.0% (7/20) 1971……35.3% (12/34) 1972……8.7% (9/104) 1973……4.3% (2/47)

      • HCV感染과 ALT와의 關係에 對한 硏究

        문희주 서울保健大學 1994 論文集 Vol.14 No.1

        The species of virus caused by Hepatitis were known over 25 but there were examined A type(HAV), B type(HBV). C type (HCV), D type(HDV) and E type(HEV) in its essence. Recently the study is receving about F type. In all viruses, HCV was known lately, 47~68% of NANB type hepatitis were HCV antibody(+), 43~74% NANB type-hepatic cirrhosis were patients HCV antibody(+). It is suggested that HCV acts on a factor of various hepatopathy included hepatoma. But only HCV make dear caused by C type hepatitis. It was not examined its structure and attribute, but made dear small virus caused by C type hepatitis. So much is trouble in diagnosis for a small percentage of the blood circulation, a lower of immune reaction, non exploitation that raise antigen in peculiarity. The thesis was made of basal data for a diagnosis in effective and early. The object of this experiment is on 100,000 blood donor of KOREA RED-CROSS BLOOD BANK and the examinded was related among of the HCV antibody positive ratio, HCV and ALT. The results obtained were as follows : 1) The HCV antibody positive ratio is orderly 0.67% for male, 0.60% for female and 0.66% for mean, not significance between male and female. 2) According to age HCV antibody positive ratio is 2.82% over 50 ages group, 0.83% for 40~49 ages, 0.67% for 30~39 ages. 0.66% for 20~29 ages, 0.53% for 16~19 ages, therefore it is represents the highest in the prime of life for above 50 ages group. The correlation between the prime of life and young age represents significance(P<0.0l). 3) According to occupation HCV antibody positive ratio is orderly 1.57% for commerce, 0.88% for housekeeping, 0.70% for agriculture, 0.69% for businessman, 0.63% for soldier, 0.56% for public servant. 0.56% for student, therefore it is the highest engaged in commerce. When it is compared with another job series, it is significance(P<0.05). 4) The correlation between HCV infection and ALT value appeared positive ratio 0.6% in 0~19IU, 0.66% in 20~29IU. 0.57% in 30~39IU, 0.58% in 40~49IU, 0.71% m 50~59IU, 2.16% above 60IU for ALT value and the mean value of ALT is 39.86±3.54 for HCV antibody negative patients. Statistically significant difference existed between HCV infection and ALT value. 5) The correlation between RCV and HBsAg were 0.72% for HBsAg positive and 0.63% for HBsAg negative. It represented or so higher for HBsAg, no statistically significant difference existed between RCV and HBsAg.

      • 韓國人의 肝炎 B virus 抗原(HBsAg) 陽性率에 對한 調査

        문희주,윤기은,김경희,이장훈 대한임상병리사협회 1979 대한임상병리사회지 Vol.11 No.1

        A study on the positive rate of HBs Ag. among the donors who are in the prime of life in Korea which may be one of the most prevailing area of hepatitis in the world, was conducted from April lst, 1977 to March 31st, 1979 for two years by Seoul Red Cross Blood Service and its branch organs. The subjects of the research are 80.250 persons who donated their serum to above institute, and organs through out the country, and the resultsare as follows: 1. The number of 3,164 from 80,250 persons proved to be positive, showing 3.94%, and the rate of the male was indicated 1.41% higher than of the female as the former marked 4.42% while the latter 3.01%. 2. The positive rate by the year represents that it was 3.44% in 1977 and 4.36% in 1978, indicating an increasing rate of 0.92% as a result. 3. The seasonalc hange is that it shows. aneye opening 4.36% in summer (June, July and August), 4.01% in winter December, January and February), 3.74% in autumn (September, October and November), 3.61% in spring (March, April arid May) on the overage. 4. The positive rate by the age group appears as follows; The highest rate group is that of 16 to 20 years, marking 4.63% and the next is 21∼25 (3.5196), those over 36 (2.83%), 26∼30 (1.89) and the group of 31∼35(1.41%) records the minimum rate of all. 5. The positve. rate by occupations is that the top class is on the staffs of firms. representing: 5.10%. and the order of the rest is students (5.02%), the others (2.5596), the unemployed (4.41%) and merchants (0.47%). 6. The distribution by the types of blood, A (4.02%), B(3.96%) AB(4.30%), and 0(3.69%) is similar on the whole, and the remarkable disparity among the types is not found. 7. The overage rate of blood donating persons in Korea is much higher than that of the U.S.A (0.1%), Norway (0.16%), France (0.496), Italy (1.6%) and Japan (2.0%).

      • 韓國人의 健康한 靑壯年에 對한 梅毒의 血淸學的 檢査成績

        문희주 최신의학사 1980 最新醫學 Vol.23 No.3

        A study on the positive rate of Syphilis (VDRL slide, flocculation method) among the donors who are in the prime of life in Korea which may be one of the most prevailing area of Syphilis in the world, was conducted from April lst. 1977 to March, 3lst, 1979 for two years by Seoul Red Cross Blood Service and its branch organs. The subjects of the research are 80,250 persons who donated their serum to above insititute and organs through out the country an d the result are as follows: 1. The number of 287 from 80,250 persons proved to be positive, showing 0.36%. and the rate of the female was indicated 0.12% higher than that of the male as the former marked 0.44% while the latter 0.32%. 2. The positive rate by the year represents that it was 0.21% (male:0.17%. female: 0.30%) in 1977 and 0.43% (male:0.45%. female: 0.54%) in 1978. indicating an increasing rate of 0.27% (male: 0.23%, female: 0.24%) in the long run. 3. The positive rate by the age group appears as follows: The highest rate group is that of 21 to 25 years old. marking 0.63%. and the next is 26∼30 (0.52%). 31∼35 (0.32%), those over 36 (0.31%) and the group of 16∼20 (0.19%) records the minimum rate of all. 4. The positive rate by occupations is that the top class is on the unemployed of representing 1.28%. and the order of the rest is staff of firms (0.80%). the orders.(0.37%), the merchants (0.20%) and students (0.046%). 5. The seasonal change is that it shows an eye-opening 0.513% in winter (December, January and February), 0.336% in Summer (June, July and August), 0.333% in spring (March, April and May). 0.313% in autumn (September. October and November) on the overage. 6. The distribution by the type of blood is that the top one is on the type of B representing 0.43%. and the order of the rest are AB (0.38%). A(0.34%) and 0 (0.29%). 7. The positive rate of Syphilis (VDRL method) to the above groups of test person up to now has marked by 1.72%~7.4% that is estimated to be a considerably low. but the record is analized very high as compared with the 0.01%~0.04% level of the united states of America.

      • HBsAg 양성혈청에서의 HBeAg 및 anti-HBe 양성율과 ALT와의 관계 고찰

        문희주,윤기은,박정오,배형준,최범열 서울보건대학 1996 서울보건대학 부설 한국보건과학연구소 논문집 Vol.3 No.1

        The authors investigated HBeAg and anti-HBe in 1,000 cases(male 941, female 59) of HBsAg positive among the 225,512 blood donors in Seoul Nambu Blood Center in 1994. HBeAg and anti-HBe was detected by the method Enzyme Immunoassy. The results obtained were as follows ; 1. HBeAg and anti-HBe positive rates were detected 498 cases(49.8%) and 445 cases(44.5%) respectively among 1,000 cases HBsAg positive blood donors. 2. In HBsAg positive carriers, HBeAg positive rates were not significantly different between anti-HBe positive rates, but in sex were significantly different between HBeAg positive rates and anti-HBe positive rates. 3. HBeAg positive 498 cases were analyzed with age and it was found percentages of positive rates were 63.6% in 1st decade, 53.7% in 2nd decade, 20.6% in 3rd decade, 19.6% in 4th decade and 8.3% in over 5th decade, but anti-HBe positive 447 cases were 32.4% in 1st decade, 40.5% in 2nd decade, 69.2% in 3rd decade, 78.3% in 4th decade and 91. 7% in above 5th decade. 4. HBeAg positive rate decreased stepwise with age, while anti-HBe positive rate increased stepwise with age. 5. ALT abnormal cases in the HBeAg positive donors were higher than normal cases, but ALT normal cases in the anit-HBe positive donors were higher than abnormal cases.

      • KCI등재

        형광저체반응에 의한 Aspergillus spp. 의 분류에 관한 연구

        문희주,김승곤,이배함 한국균학회 1973 韓國菌學會誌 Vol.1 No.2

        Author investigates fluorence antibody reaction for the antigenic relationships between Asp·niger group, Asp·flavus and Asp·parasiticus which was indicated as follows: 1. It was concluded that there are complete differences in the antigenic properties each other because it has not cross reaction, therefore identification of strains will be simpley classified. 2. A complete cross reaction between Asp·flavus and Asp·parasiticzis in the Asp·flavus groups existed. accordingly this reaction could not identified the strain and classified between Asp. flavus and Asp. parasiticus. 3. This experiment also followed with the separated each strains from the origin(Meju. Nuruk. ATCC, NRRL), but there no differences. From the above results, this method could be classified between Asp. flavus group and Asp. niger group in the genus Aspergillus, but classification of Asp. flavus and Asp. parasiticus should hardely conclude with this method.

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