창상치유과정에서 LED 광조사가 metalloproteinases 유전자 발현에 미치는 영향

김형수 전남대학교 대학원 2007 국내석사

창상 치유과정은 콜라겐 및 비콜라겐성 물질들의 침착과 함께 matrix metalloproteinases (MMPs)와 tissue inhibitors of metalloproteinase (TIMPs)에 의한 세포외기질(extracellular matrix)의 개형(remodeling)이 필요하다. 최근 LED 광 조사는 세포 증식을 가속화 시켜 창상 치유를 돕는다고 알려져 있으나, LED 광 조사에 의한 창상 치유 기전에 대해 알려진 바는 거의 없다. 본 연구는 치은섬유아세포에서 635nm LED 광 조사 후 창상 치유과정에 관여하는 세포외기질의 개형에 필요한 MMPs 및 TIMPs 효소의 발현정도를 알아보기 위해 시행하였다. 치은섬유아세포를 일차배양하고 아라키돈산 (Arachidonic acid, AA)을 처리하여 염증 모델을 만들었다. 이어 LED 광 조사를 시행하였고, cDNA microarray 분석을 시행하였다. 아무 처리도 하지 않은 대조군, 아라키돈산을 처리한 군 그리고 아라키돈산을 처리하고 LED 광 조사를 시행한 군 등 3군으로 나누어 실험을 진행하였다. MMP-1, -2, -3, -10, -11, -14, 16, 17 및 -25 그리고 TIMP-1, -2, -3 및 -4의 발현양의 차이가 있었다. 특히, TIMP-3 유전자는 아라키돈산으로 처리한 염증모델에 비해 LED 광 조사군에서 10배 이상 발현양이 감소하였다. 이상과 같은 결과에서 LEDs 광조사는 MMPs 와 TIMPs의 발현을 변화시켰으며 특히, TIMP-3가 가장 크게 발현 변화를 보였다. 이들의 발현 양상은 LED 광 조사가 치은섬유아세포의 증식과 세포외기질의 개형에 관여하여 창상 치유에 도움을 줄 것으로 추측되었다.

扶安 地域의 地名語 硏究

김형수 전주대학교 교육대학원 1998 국내석사

This research aims for investigation of the words of place-names found here and there in Puan district from a point of the Korean language view. And it has been tried to analyze the typical formation process according to the flexibility among the words of them, also to find out the detailed flexibility relations by showing their distribution charts. Here are several fact I could reach based on this research. 1. It could be found out the words of place-names in Puan district generally named after the physical geographic setting, which is supported by the eographic feature mixed with three elements : fields, mountains, and seas. Moreover, there still remains many place-names of Puangun which are well preserved without any change from the influence of foreign origin words because of their adherent and conservative nature. So they must be good research materials for the study of Korean language throughout the times. 2. Major prefixes of the names used in Puan district are ; gan˘un-, gama-, gak-, gat-, gae-, gora-, goe-, kkot-, dae-, d˘ok-, dok-, ttan-, dwi-, (dwit-), ttong-, bat-, sae-, s˘on-, ut-, jae-, jin-, tong-, han- etc. and major surfixes of them are ; -gae, -g˘ori, -gogae, -gol, -kkoji, -gorashil, -kk˘um, -nae, -non, -dumb˘ong, -tt˘um, -dari, -d˘ung, -mae, -mi, -bawi, -baemi, -shil, -y˘o, -yi, -jae, -t˘o, -etc. 3. Considering phonological points,there are palatalizational phenomena such as 'ㄱ' /giy˘ok/ and 'ㄷ' /dig˘ut/ but not 'ㅎ' /hi˘ut/ among palatalizations in Puan place-names. 4. It is examined that the change of a single vowel in Puan's place-names was moved from the vowel having big mouth-open-degree to the one having small mouth-open-degree as you see a>ae, ae>e, ˘o>e, u>i, ˘o>i, ae>i, e>i, and from a front vowel to a back vowel such as a > ae, ˘o>ae, u>i, e>i, ae>i. 5. This paper has also been shown that being analyzed the formation organization of small place-names from the view of a theory of making new words, it is generally devided with 25 things, composed of those of the language of our own (46.8%) that is a little more, those of a Chinese letters (45.9%), and those mixed with the former and the latter(7.3%). That was caused by the idea of the populace's convenience, so our native languages shall disappear overwhelmed by the words written in Chinese letters unless there is any institutional coutermeasure's establishment. 6. It could also be found out not only nouns of frequency rate (94.7%) that has large part, but also adjectives of the frequency rate (2.4%), a few verbs, numberals, pro-nouns, and adverbs when small place-names were divided into a word class. That is deeply related to the formation of the topography, and means the expressions of fragmentary behavior and our ancestor's calculation ability about number were a little reflected. 7. It could clealy be understood for us to follow the intimacy relation of the origin of a word and the meaning of a word by systematizing universal quality about the individual place-names that we could rarely make out through the type examination according to the flexibility of the place-names. 8. The style of most lives were based on an agriculture since old times because Puan-gun consists of a plain and a seside district. Therefore, among the factors of place-names, although there are the most terms related to nature objects, a compasss direction, location and the topography, they have quite a few words directly related to a life utensil in every day life. We can also see the place-name 'yong' (means dragon) much among those related to animals, which is caused by our national strong worship ceremony about auspicious animals from the beginning. 9. It is possible to approach the identification of other place-names and the names shown in other documents, through the examination of the small place-names, moreover it should be done to make great efforts constantly as a branch of study on the words of place-name linguistics. 10. It's a pity that the names of the past are disappearing more and more because the place-names also changes throughout the times, even though they are sometimes used transmitted from generation to generation. Therefore, it is one of the most important thing for all of us to record and keep our vanishing native place-names through the systematic excavation, investigation, research and the collection of them.

하수시설 자산관리전략 수립을 위한 비용투자모델에 관한 연구

김형수 서울시립대학교 과학기술대학원 2016 국내석사

대부분의 도시기반시설의 경우 30년 이상 가는 경우가 많아 도시의 발전과 시대적인 변화를 고려할 경우 다양한 원인에 의해 개·보수가 발생하게 된다. 서울시의 하수관로는 10,392㎞중 30.5%인 3,173㎞가 50년 이상이고 노후화 수준이 거의 40년에 육박하고 있으며 현재의 내용연수 20년 기준으로 본다면 노후관로의 수치는 무려 7,620㎞로 73.3%에 달하고 있다. 단순히 내용연수 기준으로 교체 의사결정을 내린다면 서울시 전체에 투입되어야 하는 비용은 수조원을 넘어서게 되며 이러한 의사결정은 수용가능하거나 전혀 문제없는 시설까지 교체하게 되는 현상이 발생하게 된다. 우리가 성장과 개발이 동시에 이루어졌던 지난 80∼90년대 까지만 해도 이러한 부분은 큰 문제가 되질 않았다. 이에 대해 어느 누구하나 반론을 제기하는 사람도 없었고 도시확장과 발전이 진행되는 입장에서는 큰 이슈가 아니었다. 그러나 이미 개발된 도시에서는 더 이상의 새로운 도시기반시설 구축이 필요 없게 되었을 뿐 만 아니라 복지비용의 확대 증가와 시설 관리 측면의 서비스 지원을 위한 비용의 급격한 증가로 인해 기 구축된 도시기반시설의 개·보수 예산 확보가 용이하지 않은 상황에 직면하게 되었다. 본 연구는 하수시설에 대한 관리차원의 비용투자 의사결정에 중요한 영향을 주는 요소(Level of Service, LCC 등)의 검토와 이에 따른 최적 투자의사결정 방법론 개발 연구에 초점을 맞추고 있다. 즉, 대상시범 구간의 하수시설에 대한 파괴 모드를 분석하고 파괴확률과 파괴로 인한 심각도 분석 및 평가에 따른 리스크 분석을 통해 자산관리전략개발 및 비용투자 모델을 개발하는 것이다. 본 모델은 추후 지자체 등 공공기관의 하수시설에 대한 자산관리전략 등 의사결정에 활용할 수 있는 기반을 제공할 것이다. In most cases, the urban infrastructure of the city is considering the development and changes many times if you are going to have more than 30 years and maintenance caused by a variety of causes. Hasugwanro of Seoul is 30.5% of 10,392㎞ 3,173㎞ more than 50 years and are almost close to the level of deterioration '40 look at the current figures are based on the useful life of 20 years with nohugwan is reached by a whopping 73.3% 7,620㎞ . If you simply made a decision to replace the useful life based on the cost to be added to the entire Seoul it is beyond the sujowon this decision becomes a phenomenon that occurs facilities can accommodate up to replace or no problem at all. Until last 80-90's growth and development, we have got this done at the same time been able part was a big problem. Thus for anyone who did not have a single objection raised in the position that development and urban expansion progress was not a big issue. However, the already developed cities no more than a new urban infrastructure built this building not only was not needed, but due to the sharp increase in costs for the expansion and increased service support of facility management aspects of the welfare cost-based urban infrastructure and maintenance funding has been faced with the situation that is not susceptible. This study focuses on the review and its optimum investment decisions in accordance with the methodology of the research and development factors that significantly affect the cost management level investment decision-making on sanitation(Level of Service, LCC, etc.). In other words, the development of asset management strategy development and cost investment risk analysis model through the analysis and evaluation of the severity of the failure mode analysis due to the sewage system of the target pilot interval and a probability of failure and destruction. This model will provide a foundation that can be used on asset management strategies, decisions about sanitation of public institutions such as municipalities later.

공유재산 불법점유에 따른 점유회복방안에 관한 연구 : 전주시 동물원 내 휴게실 사용허가 사례와 관련하여

김형수 전북대학교 법무대학원 2009 국내석사

Through the growth of the market and civil society, a recent reform intends to ‘small but efficient government’ and this has been realized by supplying the administrative services by the private, which is originally supplied by the administration. City of Junju also permits the private to provide some of public services which was supplied by Junju. For example, Junju allows the private to possess and use a resting place ofa zoo owned by Junju. Even though the permitted use period has been expired and the resting place of the zooin the city part which is the administrative property civilians who have run the resting place has not returned it yet. According to Article 6 of the Law of Management of Public Property and Products, it regulates that nobody can use or get benefits from public properties without any permission by a local government head and article 81 of the same law regulates to impose tender if a person owns, uses, or benefits from the public property without any permission and article 83 of the same law regulates that the removal or other actions can be taken to them based on article 3 or article 6 of the Administrative Execution Law if people own the public property or install facilities without the legitimate reason. Based on the articles above, therefore, according to the procedures by the Administrative Execution Law, the Mayor of Junju seems to enable to remove the detention and recover the possession from people who possess the resting place of thezoo without any legitimate reason because the permitted period has been expired. However, the Supreme Court decided that the possession of the person who possesses illegally the resting place which is the facility of the city park is not the subject of execution by the Administrative Execution by the intendance. Due to the judgment of the Supreme Court, after Junju had to bring an eviction suit against illegal occupants, it has recovered its possession through an executor under the Civil Affairs Execution Law. Nevertheless, the illegal occupants have used the resting place illegally at least 2 years from the expiration date to the execution date. Because of that, Junju could not manage and supervise the resting place of the zoo and it eventually caused inconvenience to citizens who wantedto use the park facilities under the fresh environment. Moreover, the illegal occupants have hidden their properties and earnings while failing to pay the hire and it makes not to collect taxes by force. Because it has affected the serious deduction of city’s tax revenue, it is severely prejudicial to the public interest. This research is intended to find the legal basis to help the local government head to recover the possession of public property which has been occupied illegally and additionally to study an alternative plan of possession recovery and reorganization of relevant laws by understanding the legal characteristics of using the public property and permitting benefits from it and reinterpreting the relationship of the purpose of article 83 of the Law of Management of Public Property and Products and the nature of the Administrative Execution.

GPS와 지도매칭법을 이용한 차량항법 시스템의 구성 및 VRML을 이용한 GUI 설계

김형수 강원대학교 1998 국내석사

橋梁의 생애비용(Life Cycle Cost) 分析을 이용한 경제성 평가에 관한 硏究

김형수 부경대학교 2001 국내석사

하이브리드 차량용 외장형 오일펌프 제어장치에 대한 연구

김형수 계명대학교 지능형자동차대학원 2011 국내석사

일반적으로, 하이브리드 차량(Hybrid Electric Vehicle)은 내연 엔진과 전기 자동차의 배터리 엔진을 동시에 장착하거나, 차체의 무게를 획기적으로 줄여 공기의 저항을 최소화하는 등 기존의 일반 차량에 비해 연비 및 유해 가스 배출량을 획기적으로 줄인 차세대 차량을 말한다. 하이브리드 차량에는 변속기 내부에 구비된 오일펌프 외에도 엔진 클러치와 연결된 외장형 오일펌프가 변속기 외부에 더 구비되어 엔진 클러치와 변속기에 충분한 양의 작동유가 공급될 수 있도록 하고 있다. 통상의 오일펌프는 차량의 운행 상태 및 운전자의 조작 상태에 따라 시스템 효율 및 운전 응답성을 고려하여 저속 및 고속으로 제어되지만, 하이브리드 차량에서는 외장형 오일펌프 제어장치 및 제어방법이 매우 복잡하며 많은 개선이 필요한 실정이다. 본 연구에서는 하이브리드 차량에 적용되는 외장형 오일펌프에 다양한 제어 조건을 설정함으로써 제어 목표치에 근접할 수 있도록 구동 오차가 최소화되는 하이브리드 차량용 외장형 오일펌프 제어장치를 개발하였다. 본 연구에서 제안한 외장형 오일펌프 제어장치는 기본적으로 상시 전원, IG 전원, 릴레이 전원 세 가지를 공급 받아 동작한다. 정격 동작시의 전류가 30A이상이고 최대 전류는 45A까지 흐르는 모터를 구동하도록 제어장치가 구성되었다. 모터 RPM은 0 ~ 2500RPM 사이를 20RPM 단위로 구동이 가능하다. 모든 전자 부품은 자동차용 규격 부품을 사용했으며 하드웨어적으로는 엔진 룸에 장착되므로 -30 ~ 125도의 온도에서 동작이 가능하다. 또한 내분진, 방수등급도 최고 등급을 만족하고 에어 벤트홀을 통해 습도 유지 기능도 포함하고 있다. 개발된 오일펌프 제어 시스템은 성능시험과 환경시험을 거쳤으며 하이브리드 차량에 적용될 수 있는 신뢰성을 갖춘 것으로 판명되었다. A hybrid electric vehicle (HEV) is a type of hybrid vehicle and electric vehicle which combines a conventional internal combustion engine (ICE) propulsion system with an electric propulsion system. The presence of the electric powertrain is intended to achieve either better fuel economy than a conventional vehicle, or better performance. For hybrid electric vehicles with an internal combustion engine and an automatic transmission, it is preferable if the engine shuts down while the vehicle is stopped. By stopping the engine, the fuel economy of the vehicle is improved. However, the main transmission oil pump, which is typically driven by the rotation of the transmission input shaft, will stop pumping oil when the engine stops. But there is still a need for enough oil pressure to keep the clutches that are active in first gear (forward and low-reverse) stroked(i.e. engaged), so that the vehicle can immediately provide torque to the drive wheels when the vehicle operator demands a vehicle launch. For this reason, hybrid electric vehicle needs an auxiliary oil pump. A shut down shuttle valve switches a hydraulic circuit connection from the main pump to the auxiliary pump for a low-reverse clutch and a forward clutch when the vehicle stops in drive or low gear. In this paper, we develop a control system for auxiliary oil pumps used in hybrid electric vehicles. The control system is designed to minimize actuation errors while satisfying various controller conditions. The proposed controller for auxiliary oil pumps is powered by three kinds of voltage source - normal power, IG power, and relay power. In rating operation of the controller, current value is ranged from 30A to 45A. The RPM of the motor is ranged between 0∼2500 RPM with a step of 20 RPM. Every electric component in the control system complies with the standard specification of the vehicle and is operated in the temperature of -30∼125 ℃. The control system also guarantees the supreme degree of dust-proof and water-proof, and has humidity regulation ability through air-vent holes. The experimental results verify the integrity and applicability of the proposed control system.

最大推力을 얻기 위한 擴大 nozzle의 設計의 model化에 關한 硏究

김형수 全南大學校 大學院 1982 국내석사

The aim of this paper is to model design method to obtain maximum thrust when a divergent nozzle is used as a thruster in a reaction turbine or in a rocket. First, the continuity equation, the momentum equation, the energy equation, and the state equation are nondimen- sionalized, Using the finite difference method these equations are transformed into simultaneous linear equations and solved. And then, from the density distribution and velocity distribution at the nozzle outlet, the dimensionless thrust is evaluated. By choosing the maximum thrust point, characteristics of a divergent nozzle are determined. In order to check the accuracy, the mean Nusselt number of critical flow was evaluated and compared with Isshiki's experimental data. It was proved that the difference was not significant, So this analizing method can be used with a reliable accuracy.

한국의 독도영유권에 관한 연구 : 한·일 양국의 기본입장을 중심으로

김형수 경상대학교 2003 국내석사

復部損傷의 臨床的 硏究

김형수 忠南大學校 大學院 1979 국내석사

A clical study of 238 cases of traumatic abdominal injuries who were treated atthe department of surgery, Chungnam National University Hospital during the past 12 years and 4 months, from April, 1966 to August, 1978 was performed. After clinical review, following results were obtained. 1. The sex distribution was 212 males (89.1%.) and 26 females (10.9%) with 3rd and 4 th decades (55.4%) 2. The seasonal distribution showed the highest incidence in summer involving 77 cases (32.8%) 3. Among 238 cases, 171 cases (71.8%) were blunt injury and 67 cases (28.2%) were penetrating injuries. The causes of injury, in order of decreasing frequency, were traffic accidents: 84 cases (35.3%), stab wounds: 57case(23.9%), violence: 48 cases (20.2%), falling down from height: 29 cases(12.1%), gunshots: 6 cases(2.5%). 4. The cases who were operated with in 6 hours from injury were 69 cases (30.7%) and the majority of cases 149 cases (66.3%) within 12 hours. 5. The clinical manifestation were abdominal pain(97.0%), abdominal tenderness (91.1%), rebound tenderness (79.4%), abdominal rigidity(67.2%), diminish peristalsis (57.9%), and abdominal distention (39.9%). 6. Preoperative leukocytosis were noticed in 79.6% of cases. Abdominal pracentesis was valuable in diagnosis of blunt abdominal trauma and 50 cases (81.9%) of 61 cases had positive finding. Free air was presented in (73.7%) of hollow viscus perforation. 7. The involved intra-abdominal organs, in order of frequency, was small bowel (32.5%), spleen (11.9%), river (10.9%), kidney (8.5%), retroperitoneum (6.5%) stomach (6.1%), colon(6.1%), and mesentery (5.8%). 8. 124 cases (56.8%) had single organ involvement, 54cases (24.7%) had two organ involvement and 40 cases (18.5%)had over three organs involvement. 9. The frequently associated extra-abdominal injuries were chest injuries(16.8%), lower extremity fracture (7.1%), pelvic bone fracture (6.7%) in order of frequency. 10. Simple closure was possible in most cases of injuries of stomach and small intestine, in the injuries of kidney, nephrectomy was done in 17 cases and conservative treatment in 6 cases, Simple suture and drainage was done in most cases of liver injuries. Splenectomy was done in all cases of spleen injuries. 11. Incidence of postoperative complication was 35.7% (85 cases of total 225 cases) and frequent common complication were infection(17.2%) and pulmonary complication(6.6%). 12. Mortality rate was 6.7%, main causes of death were septisemia (37.5%) and hypovolemicshock (31.3%). 13. 127 cases (53.4%) were discharged within 2 weeks of admission.