韓國産 Comfrey의 成熟中의 一般成分과 아미노酸의 含量變化

조재흥(Jei-Heung Cho),최칠남(Chil-Nam Choi),정오진(Oh-Jin Jung),김일수(Il-Su Kim) 한국식품영양과학회 1978 한국식품영양과학회지 Vol.7 No.1

comfrey의 잎과 뿌리에 함유된 free amino acid의 종류 및 함량은 G.L.C와 T.L.C.로 측정한 결과는 다음과 같다.<br/> ① G.L.C.에 의해서 검출한 free amino acid는 13종이었으며 alanine, valine, glycine, isoleucine, methionine, aspartic acid, glutamic acid, lysine, arginine, histidine, cystine, tryphtophan, phenylalnine 등 13종이 정량되었으며 이들 중 arginine은 전질소 100%중에서 10.77%로 제일 많았고 그 다음이 glutamic acid, aspartic acid, lysine, histidine순이었다.<br/> ② T.L.C로 검출한 amino acid는 G.L.C로 검출한 것보다 cysteic acid, leucine를 검출할 수 있었으며, 정량적인 면에서도 G.L.C방법과 일치하였으나 검출감도가 나쁘고 1종은 미확인 되었다.<br/> ③ G.L.C의 분석은 T.L.C 분석보다도 검출감도가 높고 정량적이었으나 재현성이 낮았고 실험과정이 복잡하여 비용이 많이 든다.<br/> ④ comfrey 중에서 잎과 뿌리에 함유된 amino acid의 함량과 성분을 비교해볼때 잎보다는 뿌리에 amino acids의 함량과 종류가 약간 많았다.<br/> ⑤ 60일후에 채취한 comfrey뿌리의 일반성분은 수분 13.2%, 조지방 2.2%, 조단백질 22.30%, 탄수화물 37.62%, 조섬유 9.38%, 회분 15.06%로 되어 있으며 60일 전후로 하여 조단백질의 함량이 감소되고 60일이 전의 comfrey는 수분의 함량이 많았고 60일이후에 채취한 comfrey는 탄수화물 조섬유, 회분의 함량이 증가되었다.<br/> ⑥ 60일정도 성장한 comfrey가 제일 많은 amino acids을 함유하고 있으며 그 함량도 제일 많았다.<br/> ⑦ comfrey에는 많은 amino acids가 함유되어 있는 것으로 보아 동물의 사료용으로 광범위하게 쓰일 수 있으며 comfrey차 이외의 다른 가공 식품을 만들수 있으리라고 사료된다. Changes in contents of general components of comfrey cultured in Korea were experimented and amino acids were analyzed by thin layer chromatography (T. L. C.) and gas chromatography (G. L. C.).<br/> The results obtained were as follows;<br/> 1. General components of comfrey such as moisture, fat, protein, carbohydrate, crude fiber and total ash were 13.20, 2.22, 22.30, 37.62, 9.38 and 15.06%. respectively, after 60 days growth.<br/> 2. The root of comfrey after 60 days contained 6.03% of alanine, 2.24% valine, 10.77% arginine, 2.96% glycine, 4.08% histidine. 1. 54% isoleucine, 0.58% cystein, 1.72% methionine, 7.55% aspartic acid, 7.81% glutamic acid and 4.65% lysine in the gas chromatographic analysis of amino acid composition<br/> 3. The crude protein was decreased after 60 days of growth whereas the contents of carbohydrate, crude fiber and total ash were increased.<br/> 4. The total amount of amino acids in root was greater than that in leaf of comfrey.

영골(靈骨),大白 자침(刺鍼)이 족태양경근(足太陽經筋) 긴장도에 미치는 영향

조재흥 ( Jae Heung Cho ),정석희 ( Seok Hee Chung ),김성수 ( Sung Soo Kim ) 한방재활의학과학회 2006 한방재활의학과학회지 Vol.16 No.3

Objectives : To investigate the effect of Dong-si acupoint(Ling-gu, Da-bai) on the tension of Governer vessel and Bladder meridian muscle. Methods : Sample group of 15 healthy subjects had been treated by acupuncture on Dong-si acupoint(Ling-gu, Da-bai) which has been proved effective against back pain and sciatica. Control group of 15-healthful subjects had not treatment during 5 minutes after first check. Outcomes were assessed at just before a step and after 5 minutes by finger to floor method(FFM) for hamstring muscle, back distance method for erector spinae muscle and Meridian-Electromyograph( MEMG) for both muscles. Results : The tension of both muscles assessed by FFM and MEMG had decreased significantly in sample group, while muscle tension assessed by back distance method had no statistical significance. Control group had not produced meaningful consequence on all assessment. Conclusions : Dong-si acupoint(Ling-gu, Da-bai) can usefully reduce the tension of Governer vessel and Bladder meridian muscle, which is accounted for meridian muscle conducting muscle tension between two-body parts distant from each other.

Chromatography를 이용한 한국산 Comfrey의 Amino acid 분리 및 정량

曺在興,崔七男,丁梧鎭 조선대학교 기초과학연구소 1978 自然科學硏究 Vol.1 No.1

Camfrey의 잎과 뿌리에 함유된 free amino acid의 종류와 함량을 G.L.C와 T.L.C로 측정한 결과는 다음과 같다. ① GLC에 의해서 검출한free amino acid는 13종이었으며 β-alanine, Valine, glycine, Isoleusine, Methionine, Aspartic acid, Glutamine, Lysine, Arginine, Histidine, Cystine, Triphtophan, Phenylamine등 13종이 정량되었으며 이들중 Argine은 전질소 100% 중에서 10.77%로 제일 많았고 그 다음이 Glutamic acid와 Aspartic Acid, Alanine, Lysine 순이었다. ② T.L.C.로 검출한 amino acid는 G.L.C.로 검출한 것보다 Leucine, Tryptophane, Cysteic acid를 검출할 수 있었으며 定量的인 면에서도 G.L.C. 방법과 일치하였으나 검출감도가 나쁘고 1종은 미확인 되었다. ③ G.L.C.의 분석은 T.L.C.분석보다도 검출감도가 높고 정량적이었으나 재현성이 낮았고 실험과정이 복잡하여 비용이 많이든다. ④ Camfrey 중에서 잎과 뿌리에 함유된 amino acid의 함량과 성분을 비교해볼때 잎보다도 뿌리에 Amino acid의 함량과 종류가 약간 많았다. ⑤ Camfrey에는 많은 amino acid가 함유되어 있는것으로 보아 동물의 사료용으로 광범위하게 쓰일 수 있으며 Comfrey 차 이외의 다른 가공식품을 만들 수 있으리라고 사료된다. Amino acids of comfrey produced in Korea have been analyzed exclusively by gas chromatogram of Gas Chromatograph (Shimadzu, GC-1C) equiped with F.I.D. and have been identified by T.L.C. Through this analysis, the following results were obtained. 1. The quantities of free amino acids in root of comfrey analyzed by T.L.C. were determined 10.23% arginine, 7.86% glutamic acid, 7.21% aspartic acid, 6.08% alanine, 4.87% lysine 4.025% histidine, 2.90% glysine, 2.86% cysteic acid, 2.52% valine, 1.68% phenylamine, 1.52% isoleucine, 1.42% leucine, 1.25% threanine, 1.05% nethionine, 0.58% cystein, 0.56% tryptophane 2. The quantities of free amino acids in leaf of comfrey analyzed by G.L.C. were determined 9.56% arginine, 6.52% aspartic acid, 6.21% glutamic acid, 5.82% alamine, 4.02% lysine, 3.45% histidine, 2.54% glysine, 1.96% valine, 1.52% isoleusine, 1.26% threanine, 1.20% phenylamine, 0.68% methiomine and 0.21% cysteine 3. The quantities of free amino acids in comfrey were determined more at root than at leaf and almost all the essential amino acids were analysed by G.L.C.

동물실험에서 인삼의 항비만 효과: 체계적 고찰과 메타분석을 위한 연구 프로토콜

조재흥(Jae heung Cho),김고운(Koh woon Kim),박혜성(Hye sung Park),윤예지(Ye ji Yoon),송미연(Mi yeon Song) 한방비만학회 2017 한방비만학회지 Vol.17 No.1

Recently the global epidemic problem of obesity has stimulated intense interest in the study of physiological mechanisms using animal models as a way to gain crucial data required for translation to human studies. Panax ginseng has been reported to have anti-obesity or antidiabetic effects in many animal studies; however, there have been few studies investigating human obesity. Herein, we will assess and examine the evidence supporting the anti-obesity effect of Panax ginseng in animal models with respect to anthropometric and metabolic outcomes. We will include controlled, comparative studies assessing the effect of Panax ginseng in preclinical studies of obesity. Panax ginseng will be administered during or following the induction of experimental obesity. The primary outcome measure will be anthropometric assessment and the secondary outcome measures will include adipose tissue weight, total amount of food consumed and metabolic parameters. We will search MEDLINE, Embase, PubMed, Web of Science, and Scopus without language, publication date, or other restrictions. Ethical approval will not be necessary as the data collected in this study will not be individual patient data, consequently there will be no concerns about violations of privacy. After finishing the whole procedure, the results will be disseminated by publication in a peer-reviewed journal or presented at a relevant conference. This protocol has been registered on the Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies (CAMARADES) website (http://www.camarades.info). 최근 비만이 전 세계적인 문제로 대두되면서 임상 연구의 해석에 필요한 중요 자료를 제시해 줄 수 있는 동물 모델을 이용한 생리학적 기전 연구에 대한 관심이 높아지고 있다. 인삼은 많은 동물 실험에서 항비만 또는 항당뇨 효과가 보고되었으나 인체의 임상에서 비만을 연구한 논문은 거의 없는 실정이다. 이 연구에서는 신체계측치수와 대사지표를 활용한 동물 모델에서의 인삼의 항비만 효과의 근거수준을 평가하고자 한다. 전임상 단계에서 비만에 대한 인삼의 효과를 연구한 대조군 연구, 비교 연구를 포함시키고자 한다. 실험적으로 비만을 유도하는 도중 혹은 이후에 인삼을 투여하고, 일차평가변수는 신체계측치수, 이차평가변수는 지방조직의 무게, 섭취음식의 총량, 대사지표 등을 포함한다. 언어, 출판일 등 특별한 제한 없이 MEDLINE, Embase, PubMed, Web of Science, Scopus를 통해 논문 검색을 시행한다. 본 연구에서의 자료 수집은 개인 정보를 포함하지 않으며, 사생활 침해의 우려가 없으므로 윤리적 승인 대상에서 제외된다. 연구의 전체과정을 수행한 후 연구결과는 연관 저널에 출간하거나 관련 학회에 발표할 예정이다. 본 연구 프로토콜은 the Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies (CAMARADES) website (http://www.camarades.info)에 등록되었다.

방광암의 예후

조재흥 藥業新聞社 1993 醫藥情報 Vol.1993 No.4

고환종양의 진단과 치료

조재흥 한국의학사 1984 診斷과治療 Vol.4 No.12

Gout와 통풍(痛風)의 어원 형성과 번역 과정에 관한 의사학적 고찰

조재흥(CHO Jae-Heung),정재영(JUNG Jae Young) 대한의사학회 2015 醫史學 Vol.24 No.2

This study aims to address questions regarding the translation of ‘gout’ into ‘tongfeng (痛風)’ in East Asia. To this end, the formation process of the origins, ‘gout’ from Western medicine and ‘tongfeng’ from Oriental medicine, and the translational process were investigated through the relevant records and literature dating from the 16th century on. Symptoms associated with gout were originally mentioned in ancient Egypt and various terminologies were used to refer to gout, such as podagra, cheiragra and gonogra. The word ‘gout’, which is derived from Latin, was used for the first time in the 13th century. The reason for this linguistic alteration is thought to be the need for a comprehensive term to cover the various terms for gout in symptomatic body parts, since it can occur concurrently in many joints. However, it took hundreds of years before gout was independently established as a medical term. In oriental medicine, terms describing diseases with features similar to gout include bibing (痺病), lijiefeng (歷節風), baihufeng (白虎風) and tongfeng (痛風). Among them, the concept of ‘tongfeng’ has been established since the Jin and Yuan dynasties. The cause, prevention and various treatments for tongfeng were proposed throughout the Ming and Qing dynasties. The early translation of gout and tongfeng in East Asia, respectively, is estimated to have occurred in the 18th century. The first literature translating gout in China was ‘An English and Chinese Vocabulary in the Court Dialect (yinghua yunfu lijie, 英華韻府歷階)’. From the publication of this book until the late 19th century, gout was translated into an unfamiliar Chinese character ‘Jiu feng jiao (酒風脚)’, likely because the translation was done mostly by foreign missionaries at the time, and they created a new word on the basis of Western medicine instead of researching and translating similar diseases in oriental medicine. In Japan, the first book translating gout was ‘A Pocket Dictionary of the English and Japanese Language (Eiwa taiyaku shuchin jisho, 英和??袖珍?書)’, Japan’s the first English-Japanese translation dictionary. In this book, gout was translated into tongfeng, a word adopted from oriental medicine. These differences from China are thought to be caused by Rangaku doctors (蘭方醫), who, influenced by oriental medicine in the Jin and Yuan dynasties, played an important role in translating medical terminology at that time.

두개골의 비균일 특성을 고려한 장애물 극복 무반사층 설계

조재흥(Jae Heung Cho),박찬욱(Chan Wook Park),김윤영(Yoon Young Kim) 대한기계학회 2023 대한기계학회 춘추학술대회 Vol.2023 No.5

상부 요로결석에 있어서 요중 Prostaglandin E2의 변화

조재흥,신유식 大韓泌尿器科學會 1986 Korean Journal of Urology Vol.27 No.1

중풍 편마비 환자에서 건측 상지 고정술이 상지 운동 기능에 미치는 영향

조재흥 ( Jae Heung Cho ),신동재 ( Dong Jae Shin ),김성수 ( Sung Soo Kim ),신현대 ( Hyun Dae Shin ) 한방재활의학과학회 2004 한방재활의학과학회지 Vol.14 No.3

Objectives: To investigate the efficacy of a constraint-induced therapy protocol on patients with chronic stroke. Methods: Constraint-induced theraphy applied to five hemiplegic patients who had been treated by general rehabilitation therapy upon stroke for 2 weeks. The other five hemiplegic patients had only general rehabilitation therapy during same period. Outcomes were assessed by Medical research council scale, Fugl-Meyer score (FMS), Wolf Motor Function Test (WMFT), Action Research Arm Test (ARA) and Modified Barthel Index(MBI). Results: Substantial improvements were observed on the FMS, WMFT and ARA, while MBI has not produced significantly meaningful differences between sample and control group. Conclusions: Constraint-induced theraphy may could be used as an efficacious method of improving function of upper limb motor function.