Formation of Metal Selenide and Metal-Selenium Nanoparticles using Distinct Reactivity between Selenium and Noble Metals.

Park, Se Ho,Choi, Ji Yong,Lee, Young Hwan,Park, Joon T,Song, Hyunjoon Wiley-VCH 2015 Chemistry - An Asian Journal Vol.10 No.7

<P>Small Se nanoparticles with a diameter of ?20?nm were generated by the reduction of selenium chloride with NaBH4 at -10?C. The reaction with Ag at 60?C yielded stable Ag2 Se nanoparticles, which subsequently were transformed into M-Se nanoparticles (M=Cd, Zn, Pb) through cation exchange reactions with corresponding ions. The reaction with Pt formed Pt layers that were evenly coated on the surface of the Se nanoparticles, and the dissolution of the Se cores with hydrazine generated uniform Pt hollow nanoparticles. The reaction with Au generated tiny Au clusters on the Se surface, and eventually formed acorn-shaped Au-Se nanoparticles through heat treatment. These results indicate that small Se nanoparticles with diameters of ?20?nm can be used as a versatile platform for the synthesis of metal selenide and metal-selenium hybrid nanoparticles with complex structures.</P>

Selenium nanostructure: Progress towards green synthesis and functionalization for biomedicine

Ranjitha V. R.,Rai V. Ravishankar 한국약제학회 2021 Journal of Pharmaceutical Investigation Vol.51 No.2

Background Selenium is a pivotal micronutrient required for the proper functioning of the body. Deficiency of Se leads to various diseases whereas a high dosage of Se possesses toxicity. To reduce the toxic effects of elemental selenium and to maximize its efficacy, synthesis of selenium at the nanoscale level is important. Selenium nanoparticles (SeNPs) have received considerable attention in the past few decades. Synthesis of nano selenium with unique properties is necessary for its biomedical applications. Synthesis steps involve physical, chemical and biological methods. The biological or green synthesis method is often more advantageous than other available methods because of the major drawbacks involved in those methods. Area covered SeNPs synthesised through green route, such as microbes and plants, are summarized in this review. Synthesised SeNPs that is functionalized with different biological moieties are discussed and listed. Green synthesis involves the use of eco-friendly plants and microbes as the route for the synthesis. SeNPs are non-toxic and stable due to the natural capping agent that prevents protein aggregation and maintains the stability of the nanoparticles. Expert opinion To achieve targeted drug delivery of the synthesized nanomaterials and to increase the efficacy of the SeNPs with minimal toxicity, functionalization is an essential tool in the field of nanomedicine. Functionalized SeNPs with various biological moieties offer enhanced cytotoxicity against various cancer cell lines, good stability and targeted drug delivery without non-specific interaction compared to nanoparticle alone. The present review focuses on detailed report and progress towards the green approach for SeNPs synthesis and engineering selenium nanomaterials with different moieties possibly used for various biomedical applications.

Size-controlled synthesis of chalcogen and chalcogenide nanoparticles using protic ionic liquids with imidazolium cation

Boominathan Meenatchi,Velayutham Renuga,Ayyar Manikandan 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.3

Green synthesis of selenium (chalcogen) nanoparticles (SeNPs) has been successfully attained by simple wet chemical method that involves the reaction of six different protic ionic liquids with imidazolium cations and sodium hydrogen selenide (NaHSe) in the presence of poly ethylene glycol-600 (PEG-600) as an additional stabilizer. The obtained SeNPs were characterized using UV spectral (UV), Fourier transform infra-red (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential thermal analysis (DTA), scanning electron microscope (SEM) with energy dispersive X-ray (EDX) and high resolution transmission electron microscope (TEM) analysis. The results illustrate that the synthesized SeNPs are spherical in shape with size ranging 19-24 nm and possess good optical property with greater band gap energy, high thermal stability up to 330 oC, low melting point of 218-220 oC comparing to precursor selenium. Using the synthesized SeNPs, two chalcogenides such as ZnSe and CdSe semiconductor nanoparticles were synthesized and characterized using XRD, SEM with EDX and TEM analysis. The fabricated CdSe and ZnSe nanoparticles appeared like pebble and cluster structure with particle size of 29.97 nm and 22.73 nm respectively.

A comparative study on the hepatoprotective effect of selenium-nanoparticles and dates flesh extract on carbon tetrachloride induced liver damage in albino rats

Ghada Nady Ouais,Doaa Mohamad Hassan 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.4

Exposure to environmental pollutants such as carbon tetrachloride (CCL4) causes liver damage. This study aimed to compare the ameliorative activity of the dates flesh extract (DFE) and selenium-nanoparticles (SeNPs) on CCL4- induced hepatotoxicity and if DFE could be a useful alternative supplement. Twenty-four male albino rats were enrolled and randomly divided into four equal groups (6 rats in each group): control group received only basal diet with no medications. Group II received CCL4 in a dose of 0.5 mg/kg intraperitoneal injection twice weekly for four weeks. Group III rats were pretreated with SeNPs in a dose of 2.5 mg/kg once a day orally three times/wk for four weeks alone then combined with the previously described dose of CCL4 for another four weeks. Group IV rats were pretreated with DFE in a dose of 8 ml of the aqueous extract/kg/d orally for four weeks alone then combined with the previously described dose of CCL4 for another four weeks. The liver damage was assessed by estimation of plasma concentration of albumin and enzymes activities of alanine aminotransferase and tissue genes expression. Liver oxidation levels were assessed by measuring the tissue concentration of the malondialdehyde, superoxide dismutase, and the total glutathione. Additionally, inflammatory mediators tumour necrosis factor--α and interleukin-6 were estimated. Detecting the liver’s cellular structural damage was done by histopathological and immunohistochemical examination. This study suggests that CCL4-induced liver damage in rats can be protected by administration whether the costly SeNPs or the economical DFE.

Separation of Selenite from Inorganic Selenium Ions using TiO₂ Magnetic Nanoparticles

Kim, Jongmin,Lim, H.B. Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.11

A simple and quick separation technique for selenite in natural water was developed using $TiO_2$@$SiO_2/Fe_3O_4$ nanoparticles. For the synthesis of nanoparticles, a polymer-assisted sol-gel method using hydroxypropyl cellulose (HPC) was developed to control particle dispersion in the synthetic procedure. In addition, titanium butoxide (TBT) precursor, instead of the typical titanium tetra isopropoxide, was used for the formation of the $TiO_2$ shell. The synthesized nanoparticles were used to separate selenite ($Se^{4+}$) in the presence of $Se^{6+}$ or selenium anions for the photocatalytic reduction to $Se^0$ atom on the $TiO_2$ shell, followed by magnetic separation using $Fe_3O_4$ nanoparticles. The reduction efficiency of the photocatalytic reaction was 81.4% at a UV power of 6W for 3 h with a dark adsorption of 17.5% to the nanoparticles, as determined by inductively coupled plasma-mass spectrometry (ICP-MS). The developed separation method can be used for the speciation and preconcentration of selenium cations in environmental and biological analysis.

Separation of Selenite from Inorganic Selenium Ions using TiO2 Magnetic Nanoparticles

Jongmin Kim,H. B. Lim 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.11

A simple and quick separation technique for selenite in natural water was developed using TiO2@SiO2/Fe3O4 nanoparticles. For the synthesis of nanoparticles, a polymer-assisted sol-gel method using hydroxypropyl cellulose (HPC) was developed to control particle dispersion in the synthetic procedure. In addition, titanium butoxide (TBT) precursor, instead of the typical titanium tetra isopropoxide, was used for the formation of the TiO2 shell. The synthesized nanoparticles were used to separate selenite (Se4+) in the presence of Se6+ or selenium anions for the photocatalytic reduction to Se0 atom on the TiO2 shell, followed by magnetic separation using Fe3O4 nanoparticles. The reduction efficiency of the photocatalytic reaction was 81.4% at a UV power of 6W for 3 h with a dark adsorption of 17.5% to the nanoparticles, as determined by inductively coupled plasma-mass spectrometry (ICP-MS). The developed separation method can be used for the speciation and preconcentration of selenium cations in environmental and biological analysis.

Growth Mechanism of Amorphous Selenium Nanoparticles Synthesized by <i>Shewanella</i> sp. HN-41

TAM, Kawai,HO, Cuong Tu,LEE, Ji-Hoon,LAI, Min,CHANG, Chong Hyun,RHEEM, Youngwoo,CHEN, Wilfred,HUR, Hor-Gil,MYUNG, Nosang V. Japan Society for Bioscience, Biotechnology, and A 2010 Bioscience, Biotechnology, and Biochemistry Vol.74 No.4

<P><I>Shewanella</I> sp. HN-41 was exploited for selenium nanoparticles synthesis from aqueous selenite compounds under anaerobic conditions. Various reaction conditions, including reaction time, initial biomass, and initial selenite concentration, were systematically investigated to determine their effects on particle size distribution and formation rate. The biomass concentration of <I>Shewanella</I> sp. HN-41 had no significant effect on average particle size but strongly influenced reduction rate and size distribution. Initial selenite concentration (0.01–1.0 m<SMALL>M</SMALL>) also had no significant effect on the average particle size, but affected the early growth stage mechanism of selenium particle production, which was modeled using a Michaelis Menten model. The HR-TEM and SAED patterns indicated that the synthesized selenium nanoparticles were amorphous.</P>

Green Synthesis and Characterization of Se Nanoparticles and Nanorods

Huiyu Chen,Ji-Beom Yoo,Yaqing Liu,Guizhe Zhao 대한금속·재료학회 2011 ELECTRONIC MATERIALS LETTERS Vol.7 No.4

Selenium nanoparticles and nanorods were successfully prepared in a mixed solvent of ethylene glycol and water at a relatively low temperature of 85°C. No other surfactant or template was employed, and glucose was used as a green and mild reducing reagent in the current synthesis. The volume ratio of ethylene glycol to water played an important role for controlling the shapes of selenium products. The obtained selenium samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), Raman spectra, and UV-vis absorption spectra. The evolution process from amorphous selenium to a trigonal phase complied with a “solid-solution-solid” formation mechanism. HRTEM and SAED results indicate that the trigonal selenium nanorods grow along the [001] direction. This method might provide an environmentally-friendly and low cost route for the synthesis of other related nanomaterials with controlled morphologies.

Preparation of selenium nanoparticles from sulfated polysaccharides or sulfated amino acids

Min-Young KIM 한국생물공학회 2010 한국생물공학회 학술대회 Vol.2010 No.10

Facile technique for wool coloration via locally forming of nano selenium photocatalyst imparting antibacterial and UV protection properties

Maryam Razmkhah,Majid Montazer,Ali Bashiri Rezaie,Mahnaz Mahmoudi Rad 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.101 No.-

The lowering intake of organic dyes and their auxiliaries by employing nanoparticles for some specialtextile coloration is novel and interesting topic. Nonetheless, application of reducing, stabilizing andother chemical agents in textile nano-coloration is still undesirable from both environmental andhuman/aquatic life viewpoints. This research renders a facile technique for wool coloration throughlocally forming selenium nanoparticles using sodium selenite without using other chemicals. Beingindustrially enforceable, free from use of additional chemicals, showing photo-active ability to discolorthe dyeing effluent and low-toxic colorant are the main privileges of the used method. The wool fabricswere colored light to dark orange depending on coloration time and concentration of sodium selenite. Also, the color fastness properties against washing, rubbing and acid/alkaline spotting of prepared sampleswere excellent. Moreover, the colored fabrics indicated reasonable bactericidal and fungicidal performancestoward Escherichia coli, Staphylococcus aureus and Candida albicans (95, 70 and 100 %,respectively) and still remained compatible with human skin. The in-situ synthesis of selenium nanoparticleson wool fabric not only colored the wool but also promoted the UV-protecting performance by61.82 %, photocatalytic activity through methylene blue discoloration under sunlight by 97.22 % and tensilestrength by 11.27 %.