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( Beatriz Pérez De Las Heras ) 한국EU학회 2021 Asia-Pacific Journal of EU Studies Vol.19 No.2
The European Green Deal (EGD) is the European Union (EU)’s current comprehensive policy framework for achieving climate neutrality by 2050 in compliance with its obligations under the Paris Agreement. However, given the global nature of the climate change challenge, no internal EU policy can achieve climate neutrality if it is not backed by external climate action. Among its foreign policies, the EU is increasingly using trade as an important tool for promoting sustainability. In particular, free trade agreements with certain partner countries, such as those in the Asia Pacific region, now include chapters on trade and sustainable development. However, despite their potential to promote green cooperation, the level of environmental engagement contained in these FTAs and their enforcement in this area are limited. The EU will therefore have to reinforce the external dimension of the EGD in the coming years if it is to achieve its stated ambition of becoming the world’s first climate-neutral economy.
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Jose Javier Zamorano-Leon,Sandra Ballesteros,Natalia de las Heras,Luis Alvarez-Sala,Mariano de la Serna-Soto,Khaoula Zekri-Nechar,Gala Freixer,Bibiana Calvo-Rico,Zhengguang Yang,Jose Manuel Garcia-Gar 한국식품영양과학회 2019 Preventive Nutrition and Food Science Vol.24 No.2
Mitochondria dynamic is regulated by different proteins, maintaining a balance between fission and fusion. An imbalance towards mitochondrial fission has been associated with tumor cell proliferation. The aim of this study was to analyze whether pectin modifies the viability of human colon cancer cells and the expression of proteins involved in mitochondrial fusion and fission. The human colon carcinoma cell line HT29 cells was growth in 10% fetal bovine serum in the absence and presence of pectin. Pectin reduced HT29 cell viability in a concentration-dependent manner, reaching a plateau at 150∼300 μ㏖/L pectin. The presence of 200 μ㏖/L pectin reduced the expression of dynamin-related protein-1 and increased expression of the mitochondrial fusion-associated proteins mitofusin-1 and 2. Expression of cyclin B1, a protein involved in G2/M transition, was found decreased in pectin-incubated HT29 cells. Moreover, expression of p53 protein, the amount of p53 in the nucleous and β-galactosidase activity, which are all biomarkers for cellular senescence, were significantly higher in pectin-incubated HT29 cells than in HT29 cells incubated without pectin. Expression of the protein B-cell lymphoma 2 (Bcl-2) homologous antagonist/killer was increased in response to incubation with pectin. However, incubation with pectin did not affect expression of Bcl-2-associated X protein or Bcl-2, or the caspase-3 activity. Overall, we concluded that pectin reduces the viability of human HT29 colon cancer cells, which is accompanied with a shift in the expression of proteins associated with mitochondrial dynamics towards mitochondrial fusion. Moreover, incubation with pectin favors cellular senescence over apoptosis in HT29 cells.
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Assembly strategies of wind turbine towers for minimum fatigue damage
Nunez-Casado, Cristina,Lopez-Garcia, Oscar,de las Heras, Enrique Gomez,Cuerva-Tejero, Alvaro,Gallego-Castillo, Cristobal Techno-Press 2017 Wind and Structures, An International Journal (WAS Vol.25 No.6
The aim of this paper is to present a method to obtain the dynamic response of a wind turbine tower in time domain by means of the generation of time series and to estimate the associated fatigue damage by means of a Rainflow counting algorithm. The proposed method is based on assuming the vortex shedding is a bidimensional phenomena and on following a classical modal superposition method to obtain the structure dynamic response. Four different wind turbine tower geometric configurations have been analyzed in a range of usual wind velocities and covering extreme wind velocities. The obtained results have shown that, depending on the turbulence intensity and the mean wind velocity, there are tower geometric configurations more advantageous from the fatigue load standpoint. Consequently, the presented model can be utilized to define assembly strategies oriented to fatigue damage minimization.
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Mohammed Bedhane,Julius van der Werf,Sara de las Heras-Saldana,Leland Ackerson IV,Dajeong Lim,박병호,박미나,Seung-Hee Roh,Samuel Clark 한국축산학회 2023 한국축산학회지 Vol.65 No.6
Most carcass and meat quality traits are moderate to highly heritable, indicating that they can be improved through selection. Genetic evaluation for these types of traits is performed using performance data obtained from commercial and progeny testing evaluation. The performance data from commercial farms are available in large volume, however, some drawbacks have been observed. The drawback of the commercial data is mainly due to sorting of animals based on live weight prior to slaughter, and this could lead to bias in the genetic evaluation of later measured traits such as carcass traits. The current study has two components to address the drawback of the commercial data. The first component of the study aimed to estimate genetic parameters for carcass and meat quality traits in Korean Hanwoo cattle using a large sample size of industry-based carcass performance records (n = 469,002). The second component of the study aimed to describe the impact of sorting animals into different contemporary groups based on an early measured trait and then examine the effect on the genetic evaluation of subsequently measured traits. To demonstrate our objectives, we used real performance data to estimate genetic parameters and simulated data was used to assess the bias in genetic evaluation. The results of our first study showed that commercial data obtained from slaughterhouses is a potential source of carcass performance data and useful for genetic evaluation of carcass traits to improve beef cattle performance. However, we observed some harvesting effect which leads to bias in genetic evaluation of carcass traits. This is mainly due to the selection of animal based on their body weight before arrival to slaughterhouse. Overall, the non-random allocation of animals into a contemporary group leads to a biased estimated breeding value in genetic evaluation, the severity of which increases when the evaluation traits are highly correlated.
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Assembly strategies of wind turbine towers for minimum fatigue damage
Cristina Nunez-Casado,Oscar Lopez-Garcia,Enrique Gomez de las Heras,Alvaro Cuerva-Tejero,Cristobal Gallego-Castillo 한국풍공학회 2017 Wind and Structures, An International Journal (WAS Vol.25 No.6
The aim of this paper is to present a method to obtain the dynamic response of a wind turbine tower in time domain by means of the generation of time series and to estimate the associated fatigue damage by means of a Rainflow counting algorithm. The proposed method is based on assuming the vortex shedding is a bidimensional phenomena and on following a classical modal superposition method to obtain the structure dynamic response. Four different wind turbine tower geometric configurations have been analyzed in a range of usual wind velocities and covering extreme wind velocities. The obtained results have shown that, depending on the turbulence intensity and the mean wind velocity, there are tower geometric configurations more advantageous from the fatigue load standpoint. Consequently, the presented model can be utilized to define assembly strategies oriented to fatigue damage minimization.
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