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Guo, W.,Wang, S.H.,Cao, H.J.,Xu, K.,Zhang, J.,Du, Z.L.,Lu, W.,Feng, J.D.,Li, N.,Wu, C.H.,Zhang, L. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.1
We created a cDNA microarray representing approximately 3,500 pig genes for functional genomic studies. The array elements were selected from 6,494 cDNA clones identified in a large-scale expressed sequence tag (EST) project. These cDNA clones came from normalized and subtracted porcine adipose tissue cDNA libraries. Sequence similarity searches of the 3,426 ESTs represented on the array using BLASTN identified 2,790 (81.4%) as putative human orthologs, with the remainder consisting of "novel" genes or highly divergent orthologs. We used the gene microarray to profile transcripts expressed by adipose tissue of fatty Chinese Xiang pig (XP) and muscley Large White (LW). Microarray analysis of RNA extracted from adipose tissue of fatty XP and muscley LW identified 81 genes that were differently expressed two fold or more. Transcriptional differences of four of these genes, adipocyte fatty acid binding protein (aP2), stearyl-CoA desaturase (SCD), sterol regulatory element binding transcription factor 1 (SREBF1) and lipoprotein lipase (LPL) were confirmed using SYBR Green quantitative RT-PCR technology. Our results showed that high expression of SCD and SREBF1 may be one of the reasons that larger fat deposits are observed in the XP. In addition, our findings also illustrate the potential power of microarrays for understanding the molecular mechanisms of porcine development, disease resistance, nutrition, fertility and production traits.
Z.W. Wang,Y.M. Wang,Y. Liu,J.L. Xu,L.X. Guo,Y. Zhou,J.H. Ouyang,J.M. Dai 한국물리학회 2011 Current Applied Physics Vol.11 No.6
Ceramic coatings containing TiO_2 were formed on Ti6Al2Zr1Mo1V alloy surface by microarc oxidation (MAO) method. The microstructure, phase and chemical composition of the coatings were analyzed by SEM, XRD and EDS techniques. The coating mainly consists of rutile TiO_2 and a small amount of anatase TiO_2. The infrared emissivity values of coated and uncoated titanium samples when exposed to 700 ℃were tested. It was found that the coating exhibits a higher infrared emissivity value (about 0.9) in the wavelength range of 8―14 mm than that of the uncoated titanium alloy, although which shows a slight increase from 0.1 to 0.3 with increasing exposure time at 700 ℃. The relatively high infrared emissivity value of the MAO coating is possibly attributed to the photon emission from the as formed TiO_2 phase.
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria
Guo, Z.,Sevrioukova, I.F.,Denisov, I.G.,Zhang, X.,Chiu, T.L.,Thomas, D.G.,Hanse, E.A.,Cuellar, R.A.D.,Grinkova, Y.V.,Langenfeld, V.W.,Swedien, D.S.,Stamschror, J.D.,Alvarez, J.,Luna, F.,Galvan, A.,Bae Elsevier 2017 Cell chemical biology Vol.24 No.10
Guo, Z.,Seol, M.L.,Gao, C.,Kim, M.S.,Ahn, J.H.,Choi, Y.K.,Huang, X.J. Pergamon Press 2016 ELECTROCHIMICA ACTA Vol.211 No.-
Thiol and amino-functionalized porous Si nanowires have been demonstrated to selectively detect Cd(II) and Pb(II) with high sensitivity using square wave anodic stripping voltammetry (SWASV) analysis. Through a typical Ag-assisted chemical etching approach, uniform and porous Si nanowires have been fabricated on heavily doped Si wafer. Continuously functionalized by (3-mercaptopropyl)trimethoxysilane (MPTMS) and (3-aminopropyl)triethoxysilane (APTES), the internal and external surfaces of porous Si nanowires have been decorated with thiol and amino groups, respectively. Inspired by the intrinsic properties of porous nanostructures, their electrochemical performances toward heavy metal ions have been further evaluated. The results indicate that Cd(II) and Pb(II) can be detected with high sensitivity owing to the strong complexing capacity of thiol and amino groups. Additionally, porous Si nanowires decorated with thiol groups present different stripping behaviors from those with amino groups toward the investigated heavy metal ions, realizing the selective and simultaneous detection of Cd(II) and Pb(II). Furthermore, simultaneous detection of Cd(II) and Pb(II) has also been demonstrated without any interference and their individual high sensitivity has been fundamentally preserved. Expectedly, porous Si nanowires as an effective modifier can be further extended to selectively detect other heavy metal ions through modifying with other functional organic groups.
REAL-TIME PERSONAL DOSE MEASUREMENT AND MANAGEMENT SYSTEM RESEARCH IN CHINA
Zhang, Z.Y.,Cheng, C.,Liu, Z.S.,Yang, H.T.,Deng, C.M.,Zhang, X.,Guo, Z.J. 대한방사선 방어학회 2001 방사선방어학회지 Vol.26 No.3
The composition and design of a real-time personal dose measurement and management system are described in this paper. Accordingly, some pertinent hardware circuits and software codes including their operation modes have also been presented.
Zhang, Z.H.,Fan, X.J.,Guo, H.X.,Zhang, W.,Zhang, C.Y.,Luo, F.Y. The Korean Vacuum Society 1998 Applied Science and Convergence Technology Vol.7 No.1
Amorphous ternary $Si_xC_yN-z$ thin films were obtained by plasma enhanced chemical vapor deposition(PECVD) using $N_2, SiH_4 \;and \;C_2H_4$ as the reaction sources. The chemical state were characterized by x-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy(FTIR). The optical properties of the thin films were investigated by UV-visible spectrophotometer and ellipsometer, and the optical band gaps of thin films were determined from corresponding transmittance spectra following Tauc equation.
Chen, G.J.,Song, S.D.,Wang, B.X.,Zhang, Z.F.,Peng, Z.L.,Guo, C.H.,Zhong, J.C.,Wang, Y. Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.12
The objective of this study was to determine the effect of forage: concentrate ratio (F:C) on growth performance, ruminal fermentation and blood metabolites of housing-feeding yaks. Thirty-two Maiwa male yaks (initial body weight = $207.99{\pm}3.31kg$) were randomly assigned to four dietary treatments (8 yaks per treatment). Experimental diets were: A, B, C, D which contained 70:30, 60:40, 50:50 and 40:60 F:C ratios, respectively. Dry matter intake and average daily gain in yaks fed the C and D diets were greater (p<0.05) than yaks fed the A and B diets. No differences were found in ruminal $NH_3-N$, total volatile fatty acids, acetate, butyrate, valerate, and isovalerate concentrations. The propionate concentration was increased (p<0.05) in the C and D groups compared with the A and B diets. In contrast, the acetate to propionate ratio was decreased and was lowest (p<0.05) in the C group relative to the A and B diets, but was similar with the D group. For blood metabolites, no differences were found in serum concentrations of urea-N, albumin, triglyceride, cholesterol, low density lipoprotein, alanine aminotransferase, and aspartate aminotransferase (p>0.05) among treatments. Treatment C had a higher concentration of total protein and high density lipoprotein (p<0.05) than A and B groups. In addition, there was a trend that the globulin concentration of A group was lower than other treatments (p = 0.079). Results from this study suggest that increasing the level of concentrate from 30% to 50% exerted a positive effect on growth performance, rumen fermentation and blood metabolites in yaks.
Kai, X.Z.,Li, Z.Q.,Fan, G.L.,Guo, Q.,Xiong, D.B.,Zhang, W.L.,Su, Y.S.,Lu, W.J.,Moon, W.J.,Zhang, D. Elsevier Sequoia 2013 Materials science & engineering. properties, micro Vol.587 No.-
Reinforcement agglomeration always leads to severe stress concentration and porosity, which is detrimental to the deformation ability and mechanical properties of particulate-reinforced metal matrix composites. In this study, uniform distribution of 32vol%B<SUB>4</SUB>C has been achieved in B<SUB>4</SUB>C/Al composite by means of flake powder metallurgy (Flake PM), in which flake Al powder is used as the starting material. The flake Al powder exhibits higher apparent volume than spherical powders of the same mass, and thus can provide more space to accommodate the B<SUB>4</SUB>C particles. Therefore, compared with conventional PM, Flake PM can lead to more uniform distribution of B<SUB>4</SUB>C particles in the composite powder as well as in the consolidated composite. Meanwhile, the flake Al powder has a nano skin of Al<SUB>2</SUB>O<SUB>3</SUB>, which could be fractured and dispersed inside the fine matrix grains during consolidation, and were found to induce a higher normalized strain hardening rate for the composite during deformation. As a result, the Flake PM 32vol%B<SUB>4</SUB>C/Al composite exhibits an ultimate tensile strength of 305MPa and a uniform elongation of 6.6%, 63% stronger and 13% more ductile than its counterpart fabricated by conventional PM.