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이상곤,김윤근 東西大學校 2001 동서논문집 Vol.7 No.-
In this paper, we developed elliptic curve crypto system software package runnable on a java card and implemented ECDSA algorithm. Two versions, 16-bit version and 32bit version, are developed. The package includes addition, multiplication, inversion, and polynonlial modular arithmethic libaranes based on F2˝ and polynomial bases. The package also includes addition, subtraction, and scalar multiplication arithmetlc libraries over affine coordinate of elliptical curve. We used this library to implement ECDSA.
임우조,황재호,김윤곤 釜山水産大學校 1994 釜山水産大學 硏究報告 Vol.34 No.1
In this study, the steel pipe piping water(SSPW) and SPPW on weldment were tested by using of a cavitation erosion - corrosion test appartus with nozzle(water tunnel type) and were investigated under the marine environment of liquid. The main results obtained were as follows 1) The corrosion - erosion of weldment is more susceptible than that of base metal. 2) The weight loss rate of heat affected zone of weldment can be largely improved by the preheat, dry of base metal and electrode before welding. 3) The electrode potential becomes noble by the pre-heat, dry of base metal and electrode before welding, and the corrosion current density is decreased.
건조기에서 Amino수지 성형재료의 경화특성에 관한 연구
최재욱,최일곤,목연수,김상렬 釜慶大學校 1998 釜慶大學校 論文集 Vol.3 No.2
We studied the effect of mass transfer in a dryer on the condensation of amino resin mould material and the curing characteristics, and investigated the drying rate, the moisture and the curing fluidity according th the variations of the temperature and the drying media recycle volume which affects the mass transfer in the drying process. So, the result are summarized as follows: ① As the drying temperature increased to 70℃, 80℃ and 90℃ respectively, the drying rate became fast. ② In the same final drying time, the higher the drying temperature became, the more the moisture content of the urea resin mould material inceased. ③ Accordingly as the drying temperature increased, the moisture content of the drying material suddenly decreased in short drying time, but the moisture content increased when the drying time was between 80 minute and 120 minutes. ④ As the drying temperature increased, the curing fluidity of amino resin mould meterial decreased. ⑤ As the recycle volume of the drying media increased, the curing fluidity decreased.
Soybean growth and yield response to elevated temperature and light intensity
Young-Son Cho,Sok-Dong Kim,Bon-Chul Koo,Won-Ha Yang,Jin-Chul Shin,Young-Han Yun1,Joung-Gon Kim 한국작물학회 2008 한국작물학회 학술발표대회 논문집 Vol.2008 No.10
Changing climate could be effect on the growth of soybean and seed yield, so we evaluated newly developed soy cultivars in the point of the physiological characteristics by changing temperature and light intensity in the phytotron. Two soy cultivars evaluated in three temperature levels (T1, 20/15; T2, 25/20; T3, 30/25oC at day/night) the pot experiment in phytotron between winter and spring in 2006 and spring and summer in 2007. Increased temperature from T1 to T2 and T2 to T3 enhanced crop growth parameters greatly and shortened growth duration and increased seed yield, however, grown in winter and spring enhanced too much plant height, so plant stems were very slim and weak and it resulted in the lodging problem. In this results we can estimate warming in Korean peninsular which might be increase temperature with low light intensity, so plant breeders and physiologists should be develop improved lodging resistance cultivars under low light intensity and high temperature.
Clinical assessment and management of auricular arteriovenous malformation: retrospective study
Kim, Do Gon,Cho, Hyun Geun,Ryu, Jeong Yeop,Lee, Joon Seok,Lee, Seok Jong,Lee, Jong Min,Lee, Sang Yub,Huh, Seung,Kim, Ji Yoon,Chung, Ho Yun Korean Cleft Palate-Craniofacial Association 2021 Archives of Craniofacial Surgery Vol.22 No.3
Background: Arteriovenous malformation (AVM) which is a high-blood-flow lesion with connections between arteries and veins without an intervening capillary bed, is difficult to manage. The ear is the second most common site of extracranial AVM. However, studies regarding the management of this condition remain lacking. The purpose of this study was to share managing experiences in our center and to investigate the treatment effect through a retrospective analysis of cases. Methods: Among 265 patients with AVM treated in our vascular anomalies center between January 2008 and January 2021, 10 patients with auricular AVM were included in the study to investigate the lesion distribution, clinical stage, and treatment methods by performing a retrospective evaluation. Results: Among 10 patients, five patients had AVMs distributed in the upper half of the ear, one patient in the lower half of the ear, and four patients in whole ear, respectively. Seven patients had Schobinger stage II, and three had stage III. One patient received surgical treatment only, four patients received sclerotherapy only, and five patients received both surgical treatment and sclerotherapy. The posttreatment status was checked as controlled in two patients, improved in seven patients, persistent in one patient. There were no worsening patients. Conclusion: Auricular AVM is a disease that is difficult to manage by one specific department, thus requiring a collaborative management effort from multidisciplinary team.
Kim, Do Yun,Chae, Joo Wung,Lim, Chang Hun,Heo, Bong Ha,Park, Keun Suk,Lee, Hyung Gon,Choi, Jeong Il,Yoon, Myung Ha,Kim, Woong Mo The Korean Pain Society 2016 The Korean Journal of Pain Vol.29 No.3
Background: Nefopam has been known as an inhibitor of the reuptake of monoamines, and the noradrenergic and/or serotonergic system has been focused on as a mechanism of its analgesic action. Here we investigated the role of the spinal dopaminergic neurotransmission in the antinociceptive effect of nefopam administered intravenously or intrathecally. Methods: The effects of intravenously and intrathecally administered nefopam were examined using the rat formalin test. Then we performed a microdialysis study to confirm the change of extracellular dopamine concentration in the spinal dorsal horn by nefopam. To determine whether the changes of dopamine level are associated with the nefopam analgesia, its mechanism was investigated pharmacologically via pretreatment with sulpiride, a dopaminergic D2 receptor antagonist. Results: When nefopam was administered intravenously the flinching responses in phase I of the formalin test were decreased, but not those in phase II of the formalin test were decreased. Intrathecally injected nefopam reduced the flinching responses in both phases of the formalin test in a dose dependent manner. Microdialysis study revealed a significant increase of the level of dopamine in the spinal cord by intrathecally administered nefopam (about 3.8 fold the baseline value) but not by that administered intravenously. The analgesic effects of intrathecally injected nefopam were not affected by pretreatment with sulpiride, and neither were those of the intravenous nefopam. Conclusions: Both the intravenously and intrathecally administered nefopam effectively relieved inflammatory pain in rats. Nefopam may act as an inhibitor of dopamine reuptake when delivered into the spinal cord. However, the analgesic mechanism of nefopam may not involve the dopaminergic transmission at the spinal level.
Kim Young-Jin,Seo Hong-Yul,Park Tae-Il,Baek So-Hyeon,Shin Woon-Chul,Kim Hyun-Soon,Kim Jung-Gon,Choi Yong-Eui,Yun Song-Joong The Korean Society of Plant Biotechnology 2005 Plant molecular biology and biotechnology research Vol.7 No.3
This study was conducted to improve tocopherol (vitamin E) composition in soybean (Glycine max) by introducing a gamma-tocopherol methyl transferase (${\gamma}$-TMT) gene via Agrobacterium tumefaciens-mediated transformation. Immature cotyledon explants were cocultivated with Agrobacterium tumefaciens. Putative transgenic embryos were selected from immature cotyledons on MS medium supplemented with 40 mg/L 2,4-D containing 100 mg/L kanamycin, 500 mg/L carbenicillin and 250 mg/L cefotaxime. Plantlets were developed from somatic embryos, and then transferred to soil. Nineteen regenerated plantlets obtained on the selection medium from 1,460 cotyledons. However, only 9 plantlets were confirmed as transformed plants. Integration of the transgene into the soybean genomic DNA was confirmed by PCR and Southern blot analysis. HPLC analysis showed that the content of ${\alpha}$-tocopherol in transgenic soybean seeds (AT-1) was approximately 4-fold higher than that of non-transgenic plants. Conclusively, we obtained the transgenic soybean having increased ${\alpha}$-tocopherol content by the overexpression of ${\gamma}$-TMT transgene.
Stable isotopic labeling-based quantitative targeted glycomics (i-QTaG).
Kim, Kyoung-Jin,Kim, Yoon-Woo,Kim, Yun-Gon,Park, Hae-Min,Jin, Jang Mi,Hwan Kim, Young,Yang, Yung-Hun,Kyu Lee, Jun,Chung, Junho,Lee, Sun-Gu,Saghatelian, Alan American Institute of Chemical Engineers ; America 2015 Biotechnology progress Vol.31 No.3
<P>Mass spectrometry (MS) analysis combined with stable isotopic labeling is a promising method for the relative quantification of aberrant glycosylation in diseases and disorders. We developed a stable isotopic labeling-based quantitative targeted glycomics (i-QTaG) technique for the comparative and quantitative analysis of total N-glycans using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). We established the analytical procedure with the chemical derivatizations (i.e., sialic acid neutralization and stable isotopic labeling) of N-glycans using a model glycoprotein (bovine fetuin). Moreover, the i-QTaG using MALDI-TOF MS was evaluated with various molar ratios (1:1, 1:2, 1:5) of (13) C6 /(12) C6 -2-aminobenzoic acid-labeled glycans from normal human serum. Finally, this method was applied to direct comparison of the total N-glycan profiles between normal human sera (n = 8) and prostate cancer patient sera (n = 17). The intensities of the N-glycan peaks from i-QTaG method showed a good linearity (R(2) > 0.99) with the amount of the bovine fetuin glycoproteins. The ratios of relative intensity between the isotopically 2-AA labeled N-glycans were close to the theoretical molar ratios (1:1, 1:2, 1:5). We also demonstrated that the up-regulation of the Lewis antigen (~82%) in sera from prostate cancer patients. In this proof-of-concept study, we demonstrated that the i-QTaG method, which enables to achieve a reliable comparative quantitation of total N-glycans via MALDI-TOF MS analysis, has the potential to diagnose and monitor alterations in glycosylation associated with disease states or biotherapeutics.</P>