Use of Parathyroid Hormone and Rehabilitation Reduces Subsequent Vertebral Body Fractures after Balloon Kyphoplasty

Ueno Masaki,Toriumi Emi,Yoshii Aki,Tabata Yuki,Furudate Takeshi,Tajima Yusuke 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.3

Study Design: Retrospective cohort study.Purpose: To evaluate the efficacy of our current prophylactic strategy by investigating the incidence of subsequent vertebral body fractures (SVBFs) following balloon kyphoplasty (BKP).Overview of Literature: Although extensive studies have investigated the risk factors for SVBFs after BKP, few have reported on postoperative therapies to prevent SVBFs and have evaluated their effectiveness.Methods: This study enrolled 273 patients who underwent an initial BKP. To treat osteoporosis, parathyroid hormone (PTH) administration was started 1–2 weeks before BKP and continued for at least 6 months postoperatively. Corsets were applied for 3 months after the procedure. Rehabilitative interventions, including hip range-of-motion training, muscle strengthening exercises, and motion/posture instruction, were started from the preoperative assessment time point and resumed 3 hours postoperatively. Corsets were used in all patients. Therefore, no grouping based on corset use was performed. PTH was used in 180 patients, and they were divided into the following two groups: PTH user group and PTH nonuser group. Rehabilitative interventions were provided to all patients for a median duration of 17 days. Patients who underwent rehabilitative intervention for <17 and ≥17 days were included in the short-term and long-term intervention groups, respectively. The incidences of SVBFs for these four groups were compared.Results: SVBF occurred in 29 patients (10.6%). The SVBF incidence among patients who were prescribed all three prophylactic measures was 6.2%. The PTH user group had a significantly lower incidence of distant vertebral body fractures as compared to the PTH nonuser group. The long-term rehabilitation group had a significantly lower incidence of SVBFs and adjacent vertebral body fractures within 50 postoperative days than the short-term group.Conclusions: A 17-day or longer rehabilitative intervention may lower the risk of early adjacent vertebral body fractures, and the use of PTH may reduce the risk of distant vertebral body fractures.

INFRARED AND OPTICAL IMAGINGS OF THE COMET 2P/ENCKE DUST CLOUD IN THE 2003 RETURN

Sarugaku, Yuki,Ishiguro, Masateru,Ueno, Munetaka,Usui, Fumihiko,Reach, William T. IOP Publishing 2015 The Astrophysical journal Vol.804 No.2

<P>We report contemporaneous imaging observations of the short-period comet 2P/Encke in infrared and optical wavelengths during the 2003 return. Both images show the same unique morphology consisting of a spiky dust cloud near the nucleus and a dust trail extending along the orbit. We conducted a dynamical simulation of dust particles to characterize the morphology and found that dust particles were ejected intensively for a short duration (less than or similar to 10 days) a few days after perihelion passage. The maximum particle size is at least on the order of 1 cm in radius following a differential power-law size distribution with an index of -3.2 to -3.6. The total mass ejected in the 2003 return is at least 1.5 x 10(9) -1.2 x 10(10) kg, which corresponds to 0.003%-0.03% of the nucleus mass. We derived the albedo of the dust cloud as 0.01-0.04 at a solar phase angle of 26 degrees. 2, which is consistent with or possibly greater than that of the nucleus. We suppose that impulsive activity such as an outburst is a key to understanding the peculiar appearance of 2P/Encke.</P>

Combined Clozapine and Electroconvulsive Therapy in a Japanese Schizophrenia Patient: A Case Report

Yuta Yoshino,Yuki Ozaki,Koichiro Kawasoe,Shinichiro Ochi,Takanori Niiya,Naomi Sonobe,Teruhisa Matsumoto,Shu-ichi Ueno 대한정신약물학회 2014 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.12 No.2

Clozapine is well-known for successful use in schizophrenic patients treatment resistant to other antipsychotics. However, evenwith clozapine, 25% of schizophrenic patients are not in remission. Recently, as adjunctive treatment with clozapine, electroconvulsivetherapy has been reported to be an effective and safe adjunctive treatment. We report a Japanese schizophrenicwoman who was not in remission with clozapine alone but with both clozapine and electroconvulsive therapy.

Observational Study of Cometary Gravels Injection Around the Terrestrial Orbit

Masateru Ishiguro,Yuki Sarugaku,Munetaka Ueno 한국천문학회 2007 天文學會報 Vol.32 No.2

Long-term Observation of Gastric Adenocarcinoma of Fundic Gland Mucosa Type before and after Helicobacter pylori Eradication: a Case Report

Takahashi, Keitaro,Ueno, Nobuhiro,Sasaki, Takahiro,Kobayashi, Yu,Sugiyama, Yuya,Murakami, Yuki,Kunogi, Takehito,Ando, Katsuyoshi,Kashima, Shin,Moriichi, Kentaro,Tanabe, Hiroki,Kamikokura, Yuki,Yuzawa, The Korean Gastric Cancer Association 2021 Journal of gastric cancer Vol.21 No.1

Gastric adenocarcinoma of the fundic gland mucosa type (GA-FGM) was proposed as a new variant of gastric adenocarcinoma of the fundic gland type (GA-FG). However, at present, the influence of Helicobacter pylori and the speed of progression and degree of malignancy in GA-FGM remain unclear. Herein, we report the first case of intramucosal GA-FGM that was endoscopically observed before and after H. pylori eradication over 15 years. The lesion showed the same tumor size with no submucosal invasion and a low MIB-1 labeling index 15 years after its detection using endoscopy. The endoscopic morphology changed from 0-IIa before H. pylori eradication to 0-IIa+IIc and then 0-I after H. pylori eradication. These findings suggest that the unaltered tumor size reflects low-grade malignancy and slow growth, and that the endoscopic morphology is influenced by H. pylori eradication.

Dark red debris from three short-period comets: 2P/Encke, 22P/Kopff, and 65P/Gunn

Ishiguro, Masateru,Sarugaku, Yuki,Ueno, Munetaka,Miura, Naoya,Usui, Fumihiko,Chun, Moo-Young,Kwon, Suk Minn Elsevier 2007 Icarus Vol.189 No.1

<P><B>Abstract</B></P><P>We present observations of the extended dust structures near the orbits of three short-period comets: 2P/Encke, 22P/Kopff, and 65P/Gunn. The dust trails were originally discovered by the Infrared Astronomical Satellite (IRAS). Our observations were made using wide-field optical CCD cameras on the University of Hawaii 2.24-m telescope, the Canada–France–Hawaii 3.6-m telescope, and the Kiso 1.05-m Schmidt telescope. We compared the observed images with models and found that the extended structures seen around 2P/Encke and 22P/Kopff before perihelion passage were most likely “dust trails,” whereas images taken after perihelion passage show a high contamination by recently released particles (i.e., particles in Neck-Line structures are visible). We could not confirm the existence of a dust trail from 65P/Gunn within the field of view of the camera used. The effective sizes of the particles responsible for the scattered light were estimated at 1–100 mm (2P/Encke), 1–10 mm (22P/Kopff), and 100 μm–1 mm (65P/Gunn), respectively, which is consistent with previous studies of dust trails made with infrared space telescopes and optical telescopes. We evaluated the mass loss rates of these comets, averaged over their orbits, as reaching 48±20 kg<SUP>s−1</SUP> (2P/Encke), 17±3 kg<SUP>s−1</SUP> (22P/Kopff), and 27±9 kg<SUP>s−1</SUP> (65P/Gunn). These values are consistent with previous work. Therefore, the total amount of material ejected from these three comets is <SUP>102</SUP> kg<SUP>s−1</SUP>, which would contribute a considerable fraction of the <SUP>104</SUP> kg<SUP>s−1</SUP> lost within 1 AU that needs to be replaced if the zodiacal cloud is to be maintained in a steady state. We also found that the particles in the dust structures are significantly redder than the Sun and the zodiacal light, and might be redder than the average short-period comet nuclei. Specifically, the reflectivity gradients of 2P/Encke, 22P/Kopff, and 65P/Gunn are 13±7 (% <SUP>103</SUP> <SUP>Å−1</SUP>), 20±5 (% <SUP>103</SUP> <SUP>Å−1</SUP>), and 15±4 (% <SUP>103</SUP> <SUP>Å−1</SUP>), respectively. We examined the change in color with distance from the nucleus. No clear correlation was detected for 2P/Encke or 22P/Kopff to an accuracy of 3–11%, while the 65P/Gunn tail did show color variation, becoming redder with increasing distance from the nucleus. This dark red material, consisting of particles of sand–cobble size, has marginally escaped from the nuclei and will evolve into finer-grained interplanetary dust particles after subsequent collisions.</P>

Preliminary Screening Method for Low Bone Mineral Density Using a Self-Reported Questionnaire among Peri- and Postmenopausal Women

Yano Yudai,Iwata Eiichiro,Sada Takuya,Ueno Yuki,Hyakuda Yoshinobu,Kawasaki Sachiko,Okuda Akinori,Shigematsu Hideki,Uematsu Kota,Yajima Hiroshi,Tanaka Yasuhito 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.6

Study Design: Retrospective cohort study.Purpose: We propose a method for screening for low bone mineral density (BMD) among perimenopausal and postmenopausal women using a self-reported questionnaire.Overview of Literature: Osteoporosis is a major health problem worldwide. However, it is not cost-effective to evaluate BMD in all patients. Although several tools for predicting osteoporosis have been established, they do not focus much on low BMD prior to the development of osteoporosis.Methods: We retrospectively reviewed the medical records of 198 women aged 40–70 years who underwent mass screening for osteoporosis at our hospital between 2016 and 2019. The BMD values and the following data were collected: age, body mass index, fracture history, lower back pain, height loss, kyphosis, history of fragility fracture, family history of vertebral or hip fracture, and menopause. The reliability of each data point for the young adult mean <80% was calculated using discriminant analysis. Variables with large weight coefficients were selected and scored. This scoring tool was examined, and a cutoff score for predicting the young adult mean <80% was determined.Results: Sixty-four participants (32.3%) had a young adult mean <80%. According to the weight coefficients, the following five variables were scored as follows: age ≥60 years 3 points, body mass index <22 kg/m2 3 points, lower back pain 1 point, height loss (cm) 1 point, and menopause 1 point. The area under the receiver operating characteristic curve was 0.738 (95% confidence interval, 0.669–0.807). At cutoff scores of ≥5 and <5, the sensitivity was 82.8%, with specificity of 52.0%.Conclusions: The scoring tool performed well for predicting young adult mean <80% among perimenopausal and postmenopausal women in Japan. This tool may be useful to screen for low BMD.

Modeling and Taylormade Training Method Using Neural Network for Specific Muscle of the Upper Limb

Kazuhiko Terashima,Takanori Miyoshi,Kenta Itokazu,Yuki Ueno,Daisuke Watanabe 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10

In this paper, we present modeling and taylormade training method using neural network for specific muscle of the upper limb. Validity of neural network model is demonstrated by comparing with the previous musculo - skeletal model in actual experiments. Applying the neural network model, an optimum path maximizing the activity of an agonist muscle and minimizing that of other muscles is designed by using an optimization method. The degree of muscles revitalization is evaluated by the amplitude of EMG signal, and the effectiveness of the proposed method is demonstrated.