Original Articles : Immunohistochemical Study on Expression of CD34 in Tumors with Follicular Differentiation

( Yong Gwan Baik ),( Ho Gyun Lee ),( Hye Rim Park ),( Jin Hee Sohn ),( Jong Min Kim ) 대한피부과학회 1996 Annals of Dermatology Vol.8 No.3

혈관 평활근종을 동반한 유두상 혈관내막 증식증

백용관,김형진,이호균,김종민 ( Yong Gwan Baik,Hyung Jin Kim,Ho Gyun Lee,Jong Min Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1

Intravascular papillary endothelial hyperplasia is a relatively rare benign tumor, which is charaterized by the development of endothelial-lined papillary projections in a vascular lumen. They can occur as a pure form in which endothelial proliferation developes in a dilated vessel, a mixed form in which endothelial proliferation occurs within a pre-existing angioma. We herein report a case of intravascular papillary endothelial hyperplasia coexistent with angioleiomyoma occuring in a 54-year-old man, who had a slowly growing tumor on the right sole for 2 years. The histologic findings revealed a solitary encapsulated mass composed of smooth muscles and blood vessels in deep dermis and papillary endothelial hyperplasia in a neighboring blood vessel. (Kor J Dermatol 1997;35(1): 155-159)

Trichophyton rubrum에 의한 육아종 1예

전진곤,백용관,이호균,김종민 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.2

We report a patient with an unusual manifestation of Trichophyton rubrum infection. A 75-year-old male presented an erythematous patch with painless crusted and non-crusted nodules on the left elbow which had persisted for 5 weeks. Histologic findings of the erythematous nodule showed epidermal hyperplasia and granulomatous change in the lower dermis. Trichophyton rubrum was isolated on the fungus culture of the biopsy specimen. The patient was treated with itraconazole (100㎎/day) for 8 weeks, resulting in the clearing of the skin lesion and there has been no recurrence of any skin lesion over a 3-month' follow-up period.

Immunohistochemical Study on Expression of CD34 in Tumors with Follicular Differentiation

Kim, Jong Min,Baik, Yong Gwan,Lee, Ho Gyun,Park, Hye Rim,Sohn, Jin Hee 대한피부과학회 1996 Annals of Dermatology Vol.8 No.1

Background : In normal hair follicles, CD34 is known to be expressed in the midfollicular areas around the bulge and in the outer root sheath. Object : The purpose of this study is to know whether there is any difference in immunostaining patterns with anti-CD34 antibody among various tumors with follicular differentiation Method : We performed immunoperoxidase staining(modified ABC technique) by using a monoclonal anti-CD34 antibody(QBEND10, IgG1) on the formalin-fixed, paraffin-embedded biopsy specimens of 11 basal cell carcinomas(BCCs), 10 trichoepitheliomas(TEs), 5 proliferating trichilemmal cysts(PTCs), 9 pilomatricomas, and 9 nevus sebaceuses. Results : In normal hair follicles, strong staining around the follicles was observed just below the entrances of sebaceous ducts into the hair canals. The outermost layers of the outer root sheaths below the isthmic portions and above the papillae were also stained. Four out of 5 cases of PTC showed CD34-positive staining limited to the focal areas of 13 outer cell layers of tumor masses. Nine out of 10 cases of TE showed densely compact strong staining in the stroma just adjacent to the tumor. In BCCs, pilomatricomas, and nevus sebaceuses, there was no remarkable change in the tumor masses nor stromas just adjacent to the tumors. Conclusion : Anti-CD34 antibody staining patterns of TEs and PTCs are different from others, which will aid in the differentiation and clarifying the origin of tumors with follicular differentiation.

반안면 왜소증 환자에서의 골신장술: 증례보고

백성문,김수관,김학균,문성용,Baik, Sung-Mun,Kim, Su-Gwan,Kim, Hak-Kyun,Moon, Seong-Yong 대한구강악안면외과학회 2007 대한구강악안면외과학회지 Vol.33 No.5

Distraction osteogenesis(DO) is a surgical method of bone formation that involves an osteotomy and sequential stretching of the healing callus by gradual movement and subsequent remodeling. DO is used to correct facial asymmetry, such as in patients with hemifacial microsomia, maxillary or mandibular retrusion, cleft lip and palate, alveolar defects, and craniofacial deficiency. It is accomplished with the aid of a distraction device, which is secured with screws placed directly into bone, for a predetermined length of time. Hemifacial microsomia is characterized by unilateral facial hypoplasia, often with unilateral shortening of the mandible and subsequent malocclusion. Patients with hemifacial microsomia and facial asymmetry have a vertically short maxilla, tilted occlusal plane, and short mandible. Early treatment is necessary to avoid subsequent impaired midfacial growth. The standard treatment of these malformations consists of the application of bone grafts, which can lead to unpredictable growth. The new bone-lengthening procedure represents a limited surgical intervention and opens up a new perspective for treatment, especially in younger children with severe deformities. This report describes a case of hemifacial microsomia(Type-II left-sided hemifacial microsomia). The patient, a 10-year-old child, visited our clinic for facial asymmetry correction. He had a hypoplastic mandible, displaced ear lobe, 10 mm canting on the right side, and malocclusion. We planned DO to lengthen the left mandible in conjunction with a Le Fort I osteotomy for decanting and then perform a right intraoral vertical ramus osteotomy(IVRO). Progressive distraction at a rate of 0.5 mm/12 hours was initiated 7 days postoperatively. The duration of DO was 17 days. The consolidation period was 3 months. Satisfactory results were obtained in our case, indicating that DO can be used successfully for functional, aesthetic reconstruction of the mandible. We report a case involving DO in conjunction with orthognathic surgery for correcting mandibular hypoplasia with a review of the literature.

Effect On The Osteogenesis Of Dental Implants After Horizontal Distraction Osteogenesis With Nitrified Distractor

( Chul Min Park ),( Su Gwan Kim ),( Hak Kyun Kim ),( Seong Yong Moon ),( Ji Su Oh ),( Sung Mun Baik ),( Sung Chul Lim ) 대한악안면성형재건외과학회 2008 Maxillofacial Plastic Reconstructive Surgery Vol.30 No.2S

화상부위에 발생한 한공각화증

백용관,박성주,이호균,김종민 ( Yong Gwan Baik,Sung Ju Park,Ho Gyun Lee,Jong Min Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2

Porokeratosis is a specific disorder of keratinization characterized histologically by the presence of a cornoid lamella. Clinically, the basic lesion is a sharply demarcated hyperkeratotic plaque which may be linear, punctated, or annular with central atrophy. The etiology of the various types of porokeratosis is unknown. However, heredity, UV radiation, immunosuppression, trauma, burns, and occult infection are known to be precipitating or exacerbating factors. A 32-year-old female was burnt on her right arm and chest at the age of 12. Several years later, brownish plaques developed in these burn areas. Seven years prior to visiting our clinic, nu- merous match-head sized, peripherally elevated macules developed on the forearms and have gradually spread to the other areas of her upper and lower extremities. The histological findings of two lesions from the burn areas showed the same features including cornoid lamellae in the epidermis and fibrosis in the dermis. Howerer, the histological finding of a lesion from a non-burn area showed cornoid lamellae in the epidermis without evidence of dermal fibrosis. We believe our case is the first to be reported in Korea in which porokeratosis arose in previous burn areas. (Kor J Dermatol 1997;35(2): 396-400)

Cinnamic Aldehyde에 의한 색소성 접촉피부염의

이상훈 ( Sang Hun Lee ),백용관 ( Yong Gwan Baik ),신자경 ( Ja Gyeong Shin ),이호균 ( Ho Gyun Lee ),김종민 ( Jong Min Kim ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.3

Pigmented contact dermatitis denotes a kind of secondary hyperpigmentation resulting from recurrent contact dermatitis of low degree. Cinnamic aldehyde is a component of cinnamon,which is widely used in foods and fragrances. A 21 year-old girl presented with a well-defined dark brownish patch on right side of chest for 4 years. Histopathologic examination revealed epidermal spongiosis, hypermelanosis of basal layer, scattered melanophages and mild perivascular inflammatory cell infiltration in the upper dermis. Patch test findings were positive to fragrance mix, cinnamic aldehyde and body shampoo which was used by the patient. Peroral challenge with cinnamon tea resulted in flare-up of the positive patch-test sites and the skin lesion. (Kor J Dermatol 1996;34(3): 468-471)

모누두 종양양 변화를 보인 피지선 모반

백용관,박성주,민형근,이호균,김종민 ( Yong Gwan Baik,Sung Ju Park,Hyung Geun Min,Ho Gyun Lee,Jong Min Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.6

Cribier and Grosshans(1995) reported two cases of tumor of the follicular infundibulum(TFI) arising in nevus sebaceus for the first time. In 1961 Mehregan and Butler described a new benign adnexal neoplasm, which they called t,umor of the follicular infundi4ulurn. Since then few observations have been published. The majority of the lesions are solitary. They appeared in adults, predominantly in wornen, on the face, arm, and neck. Histopathologically, the unique feature is a benign hyperplastic lesion that extends from the follicular infundibuluni. as an epithelial plate either with underlying elastic fiber network in TFI or without underlying elastic fiber network in TFI like change. A 52-year-old man has haf a solitary, well-defined, hairless, verrucous plaque on his right supra auricular area for about 10 years. It has seerned to increase gradually in size over the last year. The histologic findings shwed a plate-like growth of epithelial cells in the upper dermis extending parallel to the epidermis with multiple connections at the lower margin of the epidermis. The peripheral cell layer of ttie tumor plate showed palisading, and centrally located cells were pale staining. Many hair follicl s, mature sebaceous glands, ectopic apocrine glands, and inflammatory cell infiltrations were present in the dermis. However, there was no elastic fiber network beneath the epithelial cell plate. We believe our case is the first to be reported in Korea as TFI-like change in nevus sebaceus. (Korean J Dermatol 1997;35(6): 1208-1211)

모기질종의 임상 및 병리조직학적 소견에 관한 연구

장홍준,백용관,김종민,손진희 ( Hong Zoon Jang,Yong Gwan Baik,Jong Min Kim,Jin Hee Sohn ) 대한피부과학회 1997 大韓皮膚科學會誌 Vol.35 No.4

Background: Pilomatricoma is a rare benign follicular tumor in Orientals. Objective : Clinical and histopathological features of the tumor were analyzed. Methods: The medical records and histopathological slides of 19 tumors from 17 patients with pilomatricoma were studied. Results : The morphology of the tumors were divided into 3 groups :1) elevated, uniform nodules(16 cases), 2) elevated, multilobulated nodules(2 cases), and 3) non-elevated, uniform nodules (1 case). Histologically, the tumors were composed of shadow cells, transitional cells, basaloid cells and squamous cells. Changes of the stroma within the tumors and the stroma overlying the tumors included vascular dilatation, RBC engorgement and infiltration of inflammatory cells. Changes of the epidermis overlying the tumors were found in 14 cases and included hyperkeratosis(14 cases), follicular plugging(2 cases), epidermis invagination(5 cases) and acanthosis nigricans-like change(3 cases). Conclusion: Clinically, pilomatricomas manifested as either a solitary nodule or two nodules. Histologically, several tumors showed palisading of basaloid cells, retraction spaces, lymphoid follicles and acanthosis nigricans-liike epidermal changes in addition to the classic features of pilomatricoma. (Kor J Dermatol 1997;35(4): 693-701)