http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Guo Jeng Tan,Sheng Hui Kioh,Sumaiyah Mat,Maw Pin Tan,Shirley Huey Ling Chan,Jacintha Mei Ying Lee,Yee Wen Tan 대한노인병학회 2023 Annals of geriatric medicine and research Vol.27 No.4
Background: Knee osteoarthritis (OA) is a common cause of physical disability among older adults. While established risk factors for knee OA include age and increased body weight, few studies have examined psychosocial risk factors or progression of knee OA. Methods: The Promoting Independence in our Seniors with Arthritis study recruited participants aged 65 years and over from orthopedic outpatients and community engagement events. Participants were invited to annual visits during which knee OA symptoms were assessed with the Knee Injury and Osteoarthritis Outcome Score (KOOS), social network using the 6-item Lubben Social Network Scale and anxiety and depression using the Hospital Anxiety and Depression scale. Knee OA worsening was defined by a 5% reduction in mean KOOS scores at the last visit compared to the first visit. Results: Data were available from 148 participants, mean age 66.2±6.5 years and 74.1% female, of whom 28 (18.9%) experienced OA worsening over a median follow-up period of 29 months. Univariate analyses revealed that age, sex, height, grip strength, and social network were associated with OA worsening. Social network remained statistically significantly associated with OA worsening after adjustment for age and sex difference (odds ratio=0.924; 95% confidence interval, 0.857–0.997). The relationship between social network and OA worsening were attenuated by both depression and handgrip strength at baseline. Conclusion: Psychological status and muscle strength may be modifiable risk factors for social network which may in turn prevent knee OA worsening and should be targeted in future intervention studies.
Flexural Behaviour of Reinforced Lightweight Foamed Mortar Beams and Slabs
Yee Ling Lee,Jee Hock Lim,Siong Kang Lim,Cher Siang Tan 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.8
This paper presents the experimental results on flexural behaviour of reinforced concrete beams and slabs made of lightweightfoamed mortar with density ranged from 1700 to 1800 kg/m3. Beam specimens consist of seven lightweight foamed mortar beamsand three normal weight concrete beams acted as the control sample. Whereas, slab specimens contain two lightweight foamedmortar slabs and two normal weight concrete slabs. Four types of lightweight foamed mortar with different cement-sand ratios andwater-cement ratios designated as LW-1, LW-2, LW-3 and LW-4 were produced in order to achieve targeted compressive strength of20 MPa at 28 days for structural usage. The results showed that reinforced lightweight foamed mortar beams sustained about 8% to34% lower ultimate load as compared to normal weight reinforced concrete with same reinforcement configuration. However,lightweight foamed mortar slab sustained higher ultimate load, averagely 18% as compared to normal weight slab. Apart from that, itwas observed that the both reinforced lightweight foamed mortar beams and slabs were weak in resisting shear forces nonethelessflexural failure cannot be ignored entirely due to the presence of excessive yielding of the steel strain data.
Calibration Practices in Clinical Mass Spectrometry: Review and Recommendations
Cheng Wan Ling,Markus Corey,Lim Chun Yee,Tan Rui Zhen,Sethi Sunil Kumar,Loh Tze Ping 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.1
Background: Calibration is a critical component for the reliability, accuracy, and precision of mass spectrometry measurements. Optimal practice in the construction, evaluation, and implementation of a new calibration curve is often underappreciated. This systematic review examined how calibration practices are applied to liquid chromatography-tandem mass spectrometry measurement procedures. Methods: The electronic database PubMed was searched from the date of database inception to April 1, 2022. The search terms used were “calibration,” “mass spectrometry,” and “regression.” Twenty-one articles were identified and included in this review, following evaluation of the titles, abstracts, full text, and reference lists of the search results. Results: The use of matrix-matched calibrators and stable isotope-labeled internal standards helps to mitigate the impact of matrix effects. A higher number of calibration standards or replicate measurements improves the mapping of the detector response and hence the accuracy and precision of the regression model. Constructing a calibration curve with each analytical batch recharacterizes the instrument detector but does not reduce the actual variability. The analytical response and measurand concentrations should be considered when constructing a calibration curve, along with subsequent use of quality controls to confirm assay performance. It is important to assess the linearity of the calibration curve by using actual experimental data and appropriate statistics. The heteroscedasticity of the calibration data should be investigated, and appropriate weighting should be applied during regression modeling. Conclusions: This review provides an outline and guidance for optimal calibration practices in clinical mass spectrometry laboratories.
Jia Ern Leong,Wai Leong Kok,Yee Ling Tan,Balwinder Singh Mann,Sadhana Mahamad 대한갑상선-내분비외과학회 2021 The Koreran journal of Endocrine Surgery Vol.21 No.1
Delayed manifestation of surgical emphysema as cervical pneumatocele post thyroid surgery is rare and unexpected that which needs to be managed appropriately. Herein we report three cases of delayed tracheal injury presenting with persistent subcutaneous emphysema, without acute respiratory distress. All three cases were managed surgically. Possible risk factors were discussed alongside hypotheses on the mechanisms of delayed tracheal injury and recommendations to prevent such complications. The management algorithm was summarized after the literature review. While surgical management is definitive, the non-surgical approach can also be a reasonable option, but requires a longer hospital stay.
Chae, Jung-Woo,Chua, Peh Siang,Ng, Terence,Yeo, Angie Hui Ling,Shwe, Maung,Gan, Yan Xiang,Dorajoo, Sreemanee,Foo, Koon Mian,Loh, Kiley Wei-Jen,Koo, Si-Lin,Chay, Wen Yee,Tan, Tira Jing Ying,Beh, Sok Yu Springer-Verlag 2018 Breast cancer research and treatment Vol.168 No.3
<P>This is the first study to show that the reduction of mtDNA content in peripheral blood is associated with the onset of CRF in patients receiving chemotherapy. Further validation studies are required to confirm the findings.</P>