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      • KCI등재

        H2S-responsive zwitterionic hydrogel as a self–healing agent for plugging microcracks in oil-well cement

        Xiaona Huang,Hao Zhang,Xuguang Wang,Xiutian Yang,Rongzhuang Lin,Fan Zhang,Ying Liu,Kun Xu,Chao Zhou,Pixin Wang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.127 No.-

        During cementing construction, H2S gas leak from micro-cracks of cement ring or cementing interface,seriously damaging wellbore integrity and shortening the life of wells. Therefore, microcrack selfhealingcement technology is of great significance for oil wells to maintain the durability of cement ringsand adapt to complex underground environments. Herein, acrylamide (AM), acrylonitrile (AN) and Nvinylformamide(NVF) were used as functional monomers, and laponite was added to prepareLaponite-poly(acrylamide-acrylonitrile-n-vinylformamide) nanocomposite hydrogel (L-PMAN) withexcellent mechanical strength as micro-crack repair agent for gas-triggered cementing cement sheath. Considering the difference of chemical environment in the process of wellbore cement slurry sealingand subsequent micro-fracture plugging, different structural units were selected to design amphotericstructure. The construction of zwitterionic structure makes it exhibit excellent swelling behavior in saltsolution while maintaining 80% of the original mechanical strength. More importantly, after adding LPMANpowder,cement stone (C1) can achieve good repair of microcracks under the trigger of H2S within3 days, and the maximum gas breakthrough pressure can reach 2.5 MPa, indicating the great potentials ofthe L-PMAN for plugging microcracks in cement sheath.

      • KCI등재

        LncRNA-GAS5/miR-382-3p axis inhibits pulmonary artery remodeling and promotes autophagy in chronic thromboembolic pulmonary hypertension

        Feng Xiaona,Wang Kaifeng,Yang Ting,Liu Yanhui,Wang Xiaodong 한국유전학회 2022 Genes & Genomics Vol.44 No.4

        Background: We have clarified the role of miR-382-3p in chronic thromboembolic pulmonary hypertension (CTEPH), but what is less clear lies in its upstream regulatory mechanism. Objective: To explore the regulation mechanism of GAS5/miR-382-3p axis on CTEPH. Methods: In vitro, we constructed cell models by treating Pulmonary Artery Smooth Muscle Cells (PASMCs) with platelet-derived growth factor-BB (PDGF-BB). The effects of different concentrations of PDGF-BB on the activity of PASMCs were tested by cell counting kit-8 (CCK-8). The upstream lncRNA of miR-382-3p was screened and confirmed through bioinformatics analysis, RNA pull-down, quantitative reverse transcription polymerase chain reaction (qRT-PCR), dual luciferase reporter gene and RNA immunoprecipitation assays. The effects of GAS5/miR-382-3p axis on the viability, migration, and expressions of autophagy- and angiogenesis-related proteins were confirmed by rescue experiments (CCK-8, wound healing and western blot). In vivo, animal models by perfusing autologous blood vessels, the effects of GAS5 overexpression or silencing on the expressions of miR-382-3p, angiogenesis- and autophagy-related genes, mean pulmonary arterial pressure (mPAP) and pulmonary artery wall were determined by biological signal acquisition system, hematoxylin-eosin staining, qRT-PCR and western blot. Results: PDGF-BB dose-dependently promoted PASMCs viability. XIST and GAS5 expressions in PASMCs were affected by the concentration of PDGF-BB, but only GAS5 can be pulled down by miR-382-3p probe. GAS5 targeted miR-382-3p to inhibit the viability and migration of PAMSCs, mPAP in CTEPH rats, pulmonary artery wall thickening and angiogenesis, and promote autophagy. Conclusions: GAS5/miR-382-3p axis is involved in the regulation of pulmonary artery remodeling and autophagy in CTEPH.

      • KCI등재

        Phenol removal via activated carbon from co-pyrolysis of waste coal tar pitch and vinasse

        Ming Gao,Xiaona Wang,Changlei Xia,Na Song,Yuhui Ma,Qunhui Wang,Tianxue Yang,Shengbo Ge,Chuanfu Wu,Su Shiung Lam 한국화학공학회 2021 Korean Journal of Chemical Engineering Vol.38 No.1

        The behavior and characteristics of phenol adsorption by activated carbon produced from co-pyrolysis of coal tar pitch and vinasse were investigated. Coal tar pitch and vinasse (mass ratio of 1 : 3) were firstly co-pyrolyzed and carbonated at 400 oC for 2 h. The carbonized material produced was then soaked with saturated KOH solution and activated at 800 oC for 1 h to form activated carbon. Results from the phenol wastewater adsorption experiments suggest that pseudo-second-order kinetics and the Weber-Morris model could reflect the time-dependent adsorption behavior of phenol wastewater by the activated carbon, revealing that internal diffusion represents the rate-limiting procedure and dominant process to control the adsorption rate in the early stage of the adsorption. Monolayer adsorption played the key role during the phenol adsorption. The adsorption was an endothermic reaction in temperature ranging from 15 oC to 35 oC, indicating that the adsorption speed could be stimulated by the increasing temperature. This study establishes a theoretical foundation for the usage and the potential application of the activated carbon derived from coal tar pitch and vinasse in wastewater treatment.

      • KCI등재

        Delay-dependent Robust Dissipative Control for Singular LPV Systems with Multiple Input Delays

        왕흠,Xian Zhang,Xiaona Yang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.2

        This paper addresses the robust dissipative control problem for the singular linear parameter-varying(LPV) systems with multiple input time-delays. First, by constructing the parameter-dependent Lyapunov functional,a delay-dependent robust dissipativity criterion for singular LPV systems with multiple state time-delaysis proposed. Second, on the basis of linear matrix inequalities (LMIs) technique, a novel delay-dependent robustdissipativity-based controller for the singular LPV delay systems is designed. Furthermore, it is proved that theresultant closed-loop system via state feedback controller is admissible and strictly robustly (Q;S;R)-dissipative. Finally, the effectiveness of the proposed method is demonstrated by three numerical examples.

      • KCI등재

        Robust Adaptive Fault-tolerant Containment Control of Networked Heterogeneous Agent Systems with Multiple Active Leaders and Mismatched Affine Uncertainties

        Heng Liu,Xin Wang,Xinrong Yang,Xiaona Yang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.1

        This paper investigates the problem of robust fault-tolerant containment control for a class of multiagent systems in which multiple active leaders and linear heterogeneous follower subsystems with mismatched affine uncertainties and actuator faults are distributed on a communication network. It first introduces a group of distributed adaptive intermediate estimators, based on which each following agent can estimate the desired containment trajectory objective. Then, by utilizing adaptive parameter estimation approach and S-procedure technique, a decentralized fault-tolerant tracking control algorithm is designed to guarantee all practical states of followers asymptotically track the desired containment trajectory even in the case of actuator faults and heterogeneous affine uncertainties. Interestingly, the main advantage of proposed fault-tolerant containment strategy is that, not only the faulty information from follower subsystems cannot affect neighbor agents, but also both actuator faults and heterogeneous affine uncertainties can be compensated in local subsystem. Finally, a numerical example is given to illustrate the effectiveness of the designed containment control protocol.

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