Numerical investigation of solitary wave interaction with a row of vertical slotted piles on a sloping beach

Jiang, Changbo,Liu, Xiaojian,Yao, Yu,Deng, Bin The Society of Naval Architects of Korea 2019 International Journal of Naval Architecture and Oc Vol.11 No.1

To improve our current understanding of tsunami-like solitary waves interacting with a row of vertical slotted piles on a sloping beach, a 3D numerical wave tank based on the CFD tool $OpenFOAM^{(R)}$ was developed in this study. The Navier-Stokes equations were employed to solve the two-phase incompressible flow, combining with an improved VOF method to track the free surface and a LES model to resolve the turbulence. The numerical model was firstly validated by our laboratory measurements of wave, flow and dynamic pressure around both a row of piles and a single pile on a slope subjected to solitary waves. Subsequently, a series of numerical experiments were conducted to analyze the breaking wave force in view of varying incident wave heights, offshore water depths, spaces between adjacent piles and beach slopes. Finally, a slamming coefficient was discussed to account for the breaking wave force impacting on the piles.

Numerical investigation of solitary wave interaction with a row of vertical slotted piles on a sloping beach

Changbo Jiang,Xiaojian Liu,Yu Yao,Bin Deng 대한조선학회 2019 International Journal of Naval Architecture and Oc Vol.11 No.1

To improve our current understanding of tsunami-like solitary waves interacting with a row of vertical slotted piles on a sloping beach, a 3D numerical wave tank based on the CFD tool OpenFOAM® was developed in this study. The Navier-Stokes equations were employed to solve the two-phase incompressible flow, combining with an improved VOF method to track the free surface and a LES model to resolve the turbulence. The numerical model was firstly validated by our laboratory measurements of wave, flow and dynamic pressure around both a row of piles and a single pile on a slope subjected to solitary waves. Subsequently, a series of numerical experiments were conducted to analyze the breaking wave force in view of varying incident wave heights, offshore water depths, spaces between adjacent piles and beach slopes. Finally, a slamming coefficient was discussed to account for the breaking wave force impacting on the piles.

Transcriptome analysis reveals critical genes and key pathways involved in early phyllotaxy development in maize

Yang Zhao,Xiaojian Peng,Wenbo Chai,Yingquan Tan,Qing Dong,Haiyang Jiang,Beijiu Cheng 한국유전학회 2017 Genes & Genomics Vol.39 No.1

Integrated networks of gene expression, hormonal signaling and metabolite sensing regulate phyllotaxy pattern development. In this study, we characterized differentially expressed genes (DEGs) between maize plants with alternate and opposite phyllotaxies. Gene ontology and Kyoto Encyclopedia of Genes and Genomes analyses showed that 2432 DEGs were involved in biological processes, molecular functions, cellular components and many pathways. Importantly, we identified 19 DEGs related to plant hormone signal transduction. Additionally, we identified four main alternative splicing types: skipped exons, retained introns, alternative 50-splice sites, and alternative 30-splice sites, which exhibited different characteristics in the alternate and opposite phyllotaxy libraries. The reliability of the sequencing data was verified through using quantitative real-time reverse transcription PCR analysis of the 19 genes: 15 were validated to play a role in phytohormone signal transduction pathways. Taken together, our data provide new insight into the mechanisms of phyllotaxy pattern development, and will increase our understanding of how relative changes in gene expression determine alternate/opposite phyllotaxy in maize.

Modularized bioceramic scaffold/hydrogel membrane hierarchical architecture beneficial for periodontal tissue regeneration in dogs

Yingming Wei,Zhongxiu Wang,Jiayin Han,Xiaojian Jiang,Lihong Lei,Xianyan Yang,Weilian Sun,Zhongru Gou,Lili Chen 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4

Background: Destruction of alveolar bone and periodontal ligament due to periodontal disease often requires surgical treatment to reconstruct the biological construction and functions of periodontium. Despite significant advances in dental implants in the past two decades, it remains a major challenge to adapt bone grafts and barrier membrane in surgery due to the complicated anatomy of tooth and defect contours. Herein, we developed a novel biphasic hierarchical architecture with modularized functions and shape based on alveolar bone anatomy to achieve the ideal outcomes. Methods: The integrated hierarchical architecture comprising of nonstoichiometric wollastonite (nCSi) scaffolds and gelatin methacrylate/silanized hydroxypropyl methylcellulose (GelMA/Si-HPMC) hydrogel membrane was fabricated by digital light processing (DLP) and photo-crosslinked hydrogel injection technique respectively. The rheological parameters, mechanical properties and degradation rates of composite hydrogels were investigated. L-929 cells were cultured on the hydrogel samples to evaluate biocompatibility and cell barrier effect. Cell scratch assay, alkaline phosphatase (ALP) staining, and alizarin red (AR) staining were used to reveal the migration and osteogenic ability of hydrogel membrane based on mouse mandible-derived osteoblasts (MOBs). Subsequently, a critical-size one-wall periodontal defect model in dogs was prepared to evaluate the periodontal tissue reconstruction potential of the biphasic hierarchical architecture. Results: The personalized hydrogel membrane integrating tightly with the nCSi scaffolds exhibited favorable cell viability and osteogenic ability in vitro, while the scratch assay showed that osteoblast migration was drastically correlated with Si-HPMC content in the composite hydrogel. The equivalent composite hydrogel has proven good physiochemical properties, and its membrane exhibited potent occlusive effect in vivo; meanwhile, the hierarchical architectures exerted a strong periodontal regeneration capability in the periodontal intrabony defect models of dogs. Histological examination showed effective bone and periodontal ligament regeneration in the biomimetic architecture system; however, soft tissue invasion was observed in the control group. Conclusions: Our results suggested that such modularized hierarchical architectures have excellent potential as a next-generation oral implants, and this precisely tuned guided tissue regeneration route offer an opportunity for improving periodontal damage reconstruction and reducing operation sensitivity.

Laparoscopic surgery contributes to a decrease in short-term complications in surgical ulcerative colitis patients during 2008–2017: a multicenter retrospective study in China

Zerong Cai,Xiaosheng He,Jianfeng Gong,Peng Du,Wenjian Meng,Wei Zhou,Jinbo Jiang,Bin Wu,Weitang Yuan,Qi Xue,Lianwen Yuan,Jinhai Wang,Jiandong Tai,Jie Liang,Weiming Zhu,Ping Lan,Xiaojian Wu 대한장연구학회 2023 Intestinal Research Vol.21 No.2

Background/Aims: The aim of this study was to analyze the chronological changes in postoperative complications in surgical ulcerative colitis patients over the past decade in China and to investigate the potential parameters that contributed to the changes. Methods: Ulcerative colitis patients who underwent surgery during 2008–2017 were retrospectively enrolled from 13 hospitals in China. Postoperative complications were compared among different operation years. Risk factors for complications were identified by logistic regression analysis. Results: A total of 446 surgical ulcerative colitis patients were analyzed. Fewer short-term complications (24.8% vs. 41.0%, P=0.001) and more laparoscopic surgeries (66.4% vs. 25.0%, P<0.001) were found among patients who received surgery during 2014–2017 than 2008–2013. Logistic regression suggested that independent protective factors against short-term complications were a higher preoperative body mass index (odds ratio [OR], 0.870; 95% confidence interval [CI], 0.785–0.964; P=0.008), laparoscopic surgery (OR, 0.391; 95% CI, 0.217–0.705; P=0.002) and elective surgery (OR, 0.213; 95% CI, 0.067–0.675; P=0.009). The chronological decrease in short-term complications was associated with an increase in laparoscopic surgery. Conclusions: Our data revealed a downward trend of short-term postoperative complications among surgical ulcerative colitis patients in China during the past decade, which may be due to the promotion of minimally invasive techniques among Chinese surgeons.