Research on Intelligent Refrigerator Design Based on User Experience

Gao Xiaodong,Jang Wansok 한국서비스디자인학회 2019 한국서비스디자인학회 학술대회자료집 Vol.2019 No.1

Book sharing product design based on user experience

Gao Xiaodong,Jang Wansok 한국서비스디자인학회 2019 한국서비스디자인학회 학술대회자료집 Vol.2019 No.2

Experimental investigation on a freestanding bridge tower under wind and wave loads

Xiaodong Bai,Anxin Guo,Hao Liu,Wenli Chen,Gao Liu,Tianchen Liu,Shangyou Chen,Hui Li 국제구조공학회 2016 Structural Engineering and Mechanics, An Int'l Jou Vol.57 No.5

Long-span cross-strait bridges extending into deep-sea waters are exposed to complex marine environments. During the construction stage, the flexible freestanding bridge towers are more vulnerable to environmental loads imposed by wind and wave loads. This paper presents an experimental investigation on the dynamic responses of a 389-m-high freestanding bridge tower model in a test facility with a wind tunnel and a wave flume. An elastic bridge model with a geometric scale of 1:150 was designed based on Froude similarity and was tested under wind-only, wave-only and wind-wave combined conditions. The dynamic responses obtained from the tests indicate that large deformation under resonant sea states could be a structural challenge. The dominant role of the wind loads and the wave loads change according to the sea states. The joint wind and wave loads have complex effects on the dynamic responses of the structure, depending on the approaching direction angle and the fluid-induced vibration mechanisms of the waves and wind

IL28B Is Associated with Outcomes of Chronic HBV Infection

Xiaodong Shi,Junqi Niu,Xiumei Chi,Yu Pan,Yanhang Gao,Wanyu Li,Chen Yang,Jin Zhong,Damo Xu,Manna Zhang,Gerald Minuk,Jing Jiang 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.3

Purpose: The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes. Materialsand Methods: IL28B genetic variations (rs12979860) were genotyped by pyrosequencingof DNA samples from 137 individuals with chronic HBV infection [50 inactive carriers (IC), 34 chronic hepatitis B (CHB), 27 cirrhosis, 26 hepatocellular carcinoma (HCC)], and 19 healthy controls. IL28A/B mRNA expression in peripheralblood mononuclear cells was determined by qRT-PCR, and serum IL28B proteinwas measured by ELISA. Results: Patients with IL28B C/C genotype had greater IL28A/B mRNA expression and higher IL28B protein levels than C/T patients. Within the various disease stages, compared to IC and healthy controls, IL28B expression was reduced in the CHB, cirrhosis, and HCC cohorts (CHB vs. IC, p=0.02; cirrhosis vs. IC, p=0.01; HCC vs. IC, p=0.001; CHB vs. controls, p<0.01; cirrhosis vs. controls, p<0.01; HCC vs. controls, p<0.01). When stratified with respect to serum HBV markers in the IC and CHB cohorts, IL28B mRNA and protein levels were higher in HBeAg-positive than negative individuals (p=0.01). Logistic regression analysis revealed that factors associated with high IL28B proteinlevels were C/C versus C/T genotype [p=0.016, odds ratio (OR)=0.25, 95% confidence interval (CI)=0.08‒0.78], high alanine aminotransferase values (p<0.001, OR=8.02, 95% CI=2.64‒24.4), and the IC stage of HBV infection (p<0.001). Conclusion: Our data suggest that IL28B genetic variations may play an important role in long-term development of disease in chronic HBV infections.

Research Progress of Hydrostatic Bearing and Hydrostatic-Hydrodynamic Hybrid Bearing in High-End Computer Numerical Control Machine Equipment

Xiaodong Yu,Weicheng Gao,Yanan Feng,Guangqiang Shi,Shihao Li,Minmin Chen,Ruiming Zhang,Junfeng Wang,Wentao Jia,Jianhua Jiao,Ruichun Dai 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.24 No.6

Hydrostatic bearing has the advantages of wide speed range, large bearing capacity, high precision and stability. Hydrostatic-hydrodynamic hybrid bearing can make up for the lack of stiffness of hydrostatic bearing and prevent tribological failure under the condition of high speed and heavy load. Therefore, hydrostatic bearing and hydrostatic-hydrodynamic hybrid bearing have become important bearing parts of high-end computer numerical control (CNC) machine equipment. The research on hydrostatic and hydrostatic-hydrodynamic open a new way for precision improvement of high-end CNC machine equipment. This paper reviews research progress of hydrostatic linear guideway, hydrostatic rest and ram, hydrostatic thrust bearing, hydrostatic-hydrodynamic thrust bearing and hydrostatic-hydrodynamic spindle of high-end CNC machine equipment, and discusses the influence of structure and working parameters on lubrication performance, accuracy and stability of bearing parts. Finally, the future research direction in hydrostatic bearing and hydrostatic-hydrodynamic hybrid bearing are suggested. This review provides a theoretical basis for design and development of high-end CNC machine equipment in the future.

Impedance Ground Faults Detection and Classification Method for DC Microgrid

Wang Xiaodong,Wang Ruojin,Liu Yingming,Gao Xing 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.6

Aiming at the practical engineering problem, it is easy to be confused and difficult to detect, such as the single pole high impedance ground fault and load switching of the DC microgrid. This paper proposes a method, which the impedance ground faults detection and classification method. Based on the combination of improved complete ensemble empirical mode decomposition with adaptive noise and random forest. First, the dependence of original signal is reduced by complete ensemble empirical mode decomposition with adaptive noise. Secondly, by comparing the cumulative slope sum k with the threshold, the abnormal conditions can be distinguished from the normal condition, load switching and the ground faults can be further distinguished through the energy ratio Rratio. Finally, the random forest is used to further classify the ground faults to achieve precise classification of impedance ground faults in the DC microgrid. The analysis of calculation examples shows the method, it is quickly and effectively to detect and classify impedance ground faults in DC microgrid quickly and effectively, without being affected by fault resistance, fault initiation time and fault location.

Catalytic oxidation of benzene over alumina-supported Cu-Mn-Ce mixed oxide catalysts

Yang Gao,Jun Xiao,Jiandong Ye,Xiaodong Huo,Yutong Shen 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.1

Based on the response surface methodology (RSM), Cu-Mn-Ce catalysts were prepared via the vacuum impregnation method. Also, Their performance in the oxidation of a tar model compound (Benzene, 5,000 ppm) was evaluated. Results show that the optimum condition is CuO-MnO content of 30% and CeO2 content of 4.4% at a calcination temperature of 620 oC for 4.1 h. In this condition, the confirmatory experiment indicates the average carbon conversion rate within half an hour (Xc-0.5h) and four hours (Xc-4h) are 99.5% and 97.1% at 300 oC, respectively, which is in good agreement with the model prediction. XRD, H2-TPR, SEM, and XPS were employed in catalyst characterization. CuO is the primary active metal in the catalysts, which is affected easily by the calcination temperature. A lower calcination temperature tends to cause a weak structure strength, but a higher temperature results in impairing the reducibility. The major roles of CeO2 are displayed in two aspects that CeO2 increases the dispersion of the active metal, enhances the catalyst stability, and increases the oxygen vacancies and improves the oxygen transfer ability. For Cu-Mn-Ce composite catalyst, the catalytic oxidization of benzene complies with the Mars-van Krevelen mechanism (MVK). The content of CuO-MnO determines the number of active sites on the catalyst, which promotes the reduction of catalyst. CeO2 plays an important role in enhancing the oxidization of the catalyst. Therefore, the ratio of CuOMnO to CeO2 in the catalyst will cause a change of the control step of the redox reaction.

Driving Mechanism of CSR Strategy in Chinese Construction Companies based on Neo-Institutional Theory

Xiaojiang Gao-Zeller,Xiaodong Li,Fan Yang,Weina Zhu 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.5

Chinese construction companies, represented by huge Chinese construction corporations (HCCCs), have taken steps to develop their CSR (corporate social responsibility) strategy. To investigate the driving mechanisms of the CSR strategy of HCCCs, an analytical framework is proposed based on neo-institutional theory to explore how organizational legitimacy affects managerial perceptible institutional pressures and ultimately affects the development of CSR strategy. Specific scales were developed for HCCCs, and a questionnaire survey was conducted. Structural equation modelling was adopted to verify the paths proposed by the theoretical model. The results show that the expectations of the public and subcontractors/suppliers do not constitute sources of HCCCs’ organizational legitimacy. Different stakeholders have different influences on different institutional pressures. Environmental organizations have the most prominent effects. Government can reduce concerns about the CSR performance of HCCCs in society, and clients have a significant influence on the formation of institutional pressure, but employees' demands still need to be taken seriously by management. Additionally, due to the lack of regulations and norms in China, the promotion of CSR strategies relies mainly on the spontaneous demands of HCCCs. The applicability of neo-institutional theory to construction corporations is verified. The identified driving mechanisms help to effectively promote business strategy for HCCCs.

Task Offloading of Intelligent Building Based on CO–HHO Algorithm in Edge Computing

Yi Lingzhi,Gao Xieyi,Li Zongpin,Feng Xiaodong,Huang Jianxiong,Liu Qiankun 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.6

With the rapid development of intelligent devices, the intelligence of buildings is becoming more and more obvious, which leads to the rapid growth of data generated by building users. The existing network bandwidth is far from enough for the transmission of existing data, which will lead to congestion in the process of data transmission. In this paper, a task offl oading strategy based on edge computing is proposed. The edge server is deployed near the data source, which mainly solves the problems of transmission delay and energy consumption of building users during task offl oading. In this paper, the mathematical model of system delay and energy consumption is established fi rst. In order to better refl ect the quality of the system, the delay and energy consumption are combined into system utility, and then the objective function is established. Since the objective function is a mixed integer nonlinear programming problem, fi nding the optimal solution usually requires exponential time complexity. Therefore, this paper fi rstly uses the Tammer decomposition method to decouple the objective function, and decomposes it into the resource allocation problem of fi xed task offl oading decision and the task offl oad problem of maximizing the objective function. Then the convex optimization (CO) theory is used to greatly reduce the complexity of the objective function and optimize the resource allocation problem. Finally, the task offl oading problem is solved by the improved Harris Hawks Optimization (HHO) . The paper compares various offl oading schemes. The simulation results show that the CO–HHO offl oading strategy based on edge computing proposed in this paper can eff ectively reduce the transmission delay and energy consumption of user tasks in intelligent buildings, and is superior to others in all aspects.

Toll-like receptor 4 on islet β cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes

Min Li,Lujun Song,Xiaodong Gao,Wenju Chang,Xinyu Qin 생화학분자생물학회 2012 Experimental and molecular medicine Vol.44 No.4

Type 1 diabetes mellitus is caused by the autoimmune destruction of β cells within the islets. In recent years,innate immunity has been proposed to play a key role in this process. High-mobility group box 1 (HMGB1), an inflammatory trigger in a number of autoimmune diseases,activates proinflammatory responses following its release from necrotic cells. Our aim was to determine the significance of HMGB1 in the natural history of diabetes in non-obese diabetic (NOD) mice. We observed that the rate of HMGB1 expression in the cytoplasm of islets was much greater in diabetic mice compared with non-diabetic mice. The majority of cells positively stained for toll-like receptor 4 (TLR4) were βcells; few α cells were stained for TLR4. Thus, we examined the effects of anti-TLR4 antibodies on HMGB1 cell surface binding, which confirmed that HMGB1 interacts with TLR4 in isolated islets. Expression changes in HMGB1 and TLR4 were detected throughout the course of diabetes. Our findings indicate that TLR4 is the main receptor on β cells and that HMGB1 may signal via TLR4 to selectively damage β cells rather than αcells during the development of type 1 diabetes mellitus.