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RISS 인기검색어
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- 저자 : Wenjun SUN (검색결과 10 건)
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Sun Xiaoxia,Zhao Yang,Meng Wenjun,Zhai Yiying 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.11
Incorrect formula of average particle vertical velocity can lead to incorrect derivation of the formula of conveying quantity, thus leading to incorrect design of the vertical screw conveyor. In this paper, the vertical velocity of rubber particles in vertical screw conveyor is analyzed by discrete element simulation, and the vertical velocity distribution of particle flow in vertical screw conveyor with different scale structure is analyzed. In order to reduce the computational burden of the training sample and improve the accuracy of the neural network prediction, the BP neural network method is employed. Firstly, the univariate vertical velocity of different influencing factors in microscale structure is trained and predicted, and then the average vertical velocity involving two important input variables, spiral speed and pipe diameter, is trained to get the predicted values of the average vertical velocity of neural network. Finally, the experimental verification is carried out. In this paper, the BP neural network model of the average vertical velocity of rubber particles is established, which not only provides a method for the establishment of other particle neural network models, but also avoids the repeated use of discrete element simulation, and saves a lot of time.
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Jing Sun,Dehua Liu,Xiang Zhu,Wenjun Huang,Liang Cheng 한국자원공학회 2020 Geosystem engineering Vol.23 No.1
The mass transfer from the matrix to the fracture face is driven by both concentration and pressure differences. In this work, high-temperature high-pressure (HPHT) systems for diffusion experiments with only concentration differences were used to determine the diffusion coefficient, and flow experiments with only pressure differences were also conducted; and the magnitude of gas molecular diffusion and its contribution to production were analyzed in this study. The results show as follows: (1) Gas flow from the matrix to the fracture system is driven by the combined effect of gas molecular diffusion and seepage. The pore structure characteristics of the reservoir and the contribution of the diffusion to the yield can vary greatly. (2) In tight reservoirs with an average permeability of 0.3067 mD, the contribution of gas molecular diffusion to the total gas mass flux is only 0.08%, while in shale reservoirs, the average permeability is 0.0015 mD; the contribution of diffusion to the total gas mass flux could be as large as 1%. (3) The contribution of molecular diffusion to gas production is closely related to the pore sizes of the porous medium. The smaller the pore sizes are, the greater the contribution of molecular diffusion to gas production.
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Wang, Wenjun,Ouyang, Kehui,Ouyang, Jianhua,Li, Haihua,Lin, Shumao,Sun, Han Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.3
The polymorphism of insulin-like growth factor I (IGF I) in 6 chicken breeds (total n=515) was detected by PCR-Pst IRFLP, and allele A (621 bp) or allele B (364 and 257 bp) were observed. In these chicken breeds, it was found that exotic chicken carried high frequencies of allele B, while Chinese native chicken breeds carried high frequencies of allele A. Meanwhile the role of IGF I was investigated in 133 Ningdu Yellow chicken and 162 Wanzhai Yellow chicken. Five growth traits were recorded for analyzing the association between IGFI gene polymorphism and performance. In both the Ningdu and Wanzhai Yellow breeds, body weight at 4 months was significantly higher with BB genotype than with AA genotype (p<0.05). Furthermore, body weight at 2 months in the Wanzhai Yellow breeds was also higher with BB genotype than with AA genotype (p<0.05). There were no differences among the genotypes for the other traits studied. Based on these results, it is necessary to do more studies on IGFI before making the IGFI locus into the application of maker-assisted selection programms.
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Zhao Yang,Sun Xiaoxia,Meng Wenjun 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.6
An incorrect formula of the average axial speed can lead to the incorrect derivation of the conveying volume formula, which in turn can produce an incorrect design of the vertical screw conveyor. In this study, the conveying model of the vertical screw conveyor and the raw coal particle model are established. Using the discrete element method, the influence of various parameters, such as the spiral speed, filling rate, pipe diameter, and pitch, on the axial velocity of the raw coal particles is calculated, simulated, and analyzed. Corresponding to the average axial velocity distribution histogram and the derivation of the particle average axial velocity formula, a theoretical basis for the optimization design of the vertical screw conveyor is provided.
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Mechanical behavior of outer square inner circular concrete-filled dual steel tubular stub columns
Fa-Xing Ding,Wenjun Wang,Xue-mei Liu,Liping Wang,Yi Sun 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.38 No.3
The mechanical behavior of the outer square inner circular concrete-filled dual steel tubular (SCCFT) stub columns under axial compression is investigated by means of experimental research, numerical analysis and theoretical investigation. Parameters such as diameter ratio, concrete strength and steel ratio were discussed to identify their influence on the mechanical properties of SCCFT short columns on the basis of the experimental investigation of seven SCCFT short columns. By establishing a finite element model, nonlinear analysis was performed to discuss the longitudinal and transverse stress of the dual steel tubes. The longitudinal stress characteristics of the core and sandwich concrete were also analyzed. Furthermore, the failure sequence was illustrated and the reasonable cross-section composition of SCCFT stub column was proposed. A formula to predict the axial load capacity of SCCFT stub column was advanced and verified by the results from experiment and the finite element.
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Meng Xin,Tian Jing,Liu Shuai,Li Ruina,Sun Jian,Liu Wenjun 한국자동차공학회 2023 International journal of automotive technology Vol.24 No.3
To evaluate the influence of polyoxymethylene dimethyl ethers (PODE) on particulate matter (PM) chemical features, PM samples emitted from diesel fuel and PODE/diesel blends at volume ratios of 10 %, 20 %, and 30 % (P10, P20, and P30) were characterized using gas chromatography-mass spectrometry, X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopic (FT-IR). Results showed that adding PODE in diesel fuel could increase the proportions of the lower carbon-atom-number components and the contents of oxygen-containing compounds in the soluble organic fractions extracted from PM samples. The ratio of oxygen to carbon (O/C), the functional groups, and the nanostructure of dry soot obtained from XPS showed that the O/C rose as the PODE volume ratio increased. The graphitization degree of dry soot decreased in the order: diesel fuel > P10 > P30 > P20. The relative content of hydroxyl functional groups exhibited the same trend, while the relative content of carbonyl functional groups exhibited an opposite trend with the graphitization degree. Moreover, according to FT-IR, both the branching degree and the relative content of hydrocarbon functional groups of aliphatics are influenced by the graphitization degree of dry soot. A turning point at P20 observed by analysis results above indicated that the chemical characteristics of PM could be affected not only by fuel properties but also by the process of fuel combustion and PM formation.
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Gong, Yingyun,Cao, Rui,Ding, Guolian,Hong, Sungguan,Zhou, Wenjun,Lu, Wenyun,Damle, Manashree,Fang, Bin,Wang, Chuhan C.,Qian, Justin,Lie, Natasha,Lanzillotta, Cristina,Rabinowitz, Joshua D.,Sun, Zheng Elsevier 2018 Molecular and cellular endocrinology Vol.471 No.-
<P><B>Abstract</B></P> <P>Nuclear receptors regulate gene expression by differentially binding to coactivators or corepressors in a ligand-dependent manner, which further recruits a set of epigenome-modifying enzymes that remodel chromatin conformation. Histone acetylation is a major epigenomic change controlled by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HDAC3 is the only HDAC that confers the enzymatic activity to the complexes nucleated by nuclear receptor corepressors NCoR and SMRT. To address the metabolic function of HDAC3, we have deleted it specifically in mouse skeletal muscles. We have performed the following omics profiling in skeletal muscles of these mice: (1) RNA-seq profiling of total RNA; (2) Global nuclear run-on (GRO-seq) analysis of nascent RNAs; (3) Chromatin immuno-precipitation (ChIP-seq) of HDAC3 at both early evening and early morning; (4) proteomics profiling with mass spectrometry; (5) snap-shot metabolomics profiling of water-soluble metabolites at the basal condition; (6) snap-shot metabolomics profiling of lipid species at the basal condition; (7) kinetic fluxomics analysis of glucose utilization using <SUP>13</SUP>C<SUB>6</SUB>-glucose <I>In vivo</I> during treadmill running exercise. These approaches have provided several novel insights into how nuclear receptors regulate circadian rhythm of skeletal muscle fuel metabolism, which has been published elsewhere. Here we present the original datasets and technical details during the execution, analysis, and interpretation of these omics studies.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A mouse model with skeletal muscle-specific KO of HDAC3. </LI> <LI> <I>in vivo</I> RNA-seq, GRO-seq, and ChIP-seq identified relevance to circadian clock. </LI> <LI> Total proteome profiling in muscle samples. </LI> <LI> Metabolomics profiling identified disruption of BCAAs metabolism. </LI> <LI> Fluxomics with <SUP>13</SUP>C-glucose <I>in vivo</I> during treadmill running. </LI> </UL> </P>
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Immunogenicity and Efficacy of Schmallenberg Virus Envelope Glycoprotein Subunit Vaccines
Abaineh D. Endalew,Bonto Faburay,Jessie D. Trujillo,Natasha N. Gaudreault,A. Sally Davis,Vinay Shivanna,Sun-Young Sunwoo,Wenjun Ma,Barbara S. Drolet,D. Scott McVey,Igor Morozov,William C. Wilson,Juerg 대한수의학회 2019 Journal of Veterinary Science Vol.20 No.6
The Schmallenberg virus (SBV) is an orthobunyavirus that causes abortions, stillbirths, and congenital defects in pregnant sheep and cattle. Inactivated or live attenuated vaccines have been developed in endemic countries, but there is still interest in the development of SBV vaccines that would allow a differentiationng of infected from vaccinated animals (DIVA). Therefore, an attempt was made to develop novel DIVA-compatible SBV vaccines using SBV glycoproteins expressed in baculovirus. All vaccines and phosphate buffered saline (PBS) controls were prepared with adjuvant and administered subcutaneously to cattle at six6 months (Ed note: Numerals 1 to 9 are written in words.)of age. The first trial included two2 groups of animals vaccinated with either carboxyl-terminus glycoprotein (Gc) or PBS and boosted after two2 weeks. In the second trial, three3 groups of cattle were administered either Gc, Gc and Gnamino-terminus glycoprotein, or PBS with a booster vaccination after three3 weeks. The animals were challenged with the SBV nine9 days after the booster vaccination in the first study, and three3 weeks after the booster vaccination in the second study. Using SBV Gc-specific ELISAenzyme-linked immunosorbent assay, antibodies were first detected in serum samples 14 days after the first vaccination in both trials, and peaked on days seven7 and nine9 after the booster in the first and second trials, respectively. Low titers of neutralizing antibodies were detected in serum from only 3/6 and 2/4 animals in the first and second trial, respectively, at 14 days after the first vaccination. The titers increased 2 to 3-fold after the booster vaccination. On the other hand, SBV-specific RNA was detected in the serum and selective tissues in all animals after the challenge. The SBV candidate vaccines neither prevented viremia nor conferred protection against the SBV infection.
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