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RISS 인기검색어
- 검색키워드
- 저자 : Valerie Ow (검색결과 2 건)
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High School Students' Perceived Creativity Self-efficacy and Emotions in a Service Learning Context
Ai-Girl Tan,Valerie Ho,Elizabeth Ho,Steve Ow 대한사고개발학회 2008 The International Journal of Creativity & Problem Vol.18 No.2
Our study examined the relationship of creativity self-efficacy and emotions of high school students (n = 279) in Singapore before and after they attended a three to five-day international service learning program. Participants completed a creativity self efficacy scale, the Positive Affect and Negative Affect Scale (PANAS), Satisfaction With Life Scale (SWLS) and Subjective Happiness Scale (SHS). We found a positive, significant correlation between creativity efficacy and positive affect, life satisfaction and subjective happiness but negative correlation with negative mood affect. In addition, students whose creativity efficacy was moderately high were found to have reported higher ratings of life satisfaction after having participated in service learning. Our findings provide initial evidence suggesting that service learning with positive intervention is positively related to creativity self-efficacy and happiness of youth.
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Injectable PTHF-based thermogelling polyurethane implants for long-term intraocular application
Kaiwen Zhang,Zengping Liu,Qianyu Lin,Yi Jian Boo,Valerie Ow,Xinxin Zhao,Daniel Soo Lin Wong,Jason Y. C. Lim,Kun Xue,Xinyi Su,Decheng Wu,Xian Jun Loh 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4
Background: Hydrogels show great potential to be used for intraocular applications due to their high-water content and similarity to the native vitreous. Injectable thermosensitive hydrogels through a small-bore needle can be used as a delivery system for drugs or a tamponading substitute to treat posterior eye diseases with clear clinical potential. However, none of the currently available thermosensitive hydrogels can provide intraocular support for up to 3 months or more. Method: In this study, an injectable polytetrahydrofuran (PTHF)-based thermosensitive hydrogel was synthesized by polyurethane reaction. We examined the injectability, rheological properties, microstructure, cytotoxicity, and in vivo compatibility and stability of the hydrogels in rabbit eyes. Results: We found that the PTHF block type and PTHF component ratio could modulate thermogelation properties of the polyurethane polymers. The PTHF-based hydrogel implants retained normal retinal structure and function. Incorporating bioinert PTHF generated highly biocompatible and more stable thermogels in the vitreous cavity, with gel networks and the presence of polymer still observed after 3 months when other thermogels would have been completely cleared. Moreover, despite lacking hydrolytically cleavable linkages, the polymers could be most naturally removed from the native vitreous by bio-erosion without additional surgical interventions. Conclusion: Our findings suggest the potential of incorporating hydrophobic bioinert blocks to enhance the in vivo stability of supramolecularly associated hydrogels for long-term intraocular applications.
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