A new transmission rate upper bound of HK scheme for Interference system with M-QAM

Fan Tingting,Yang Wei,Xu Changlong,Young-il Kim ICT플랫폼학회 2015 JOURNAL OF PLATFORM TECHNOLOGY Vol.3 No.4

Primordial Drivers of Diabetes Heart Disease: Comprehensive Insights into Insulin Resistance

Yajie Fan,Zhipeng Yan,Tingting Li,Aolin Li,Xinbiao Fan,Zhongwen Qi,Junping Zhang 대한당뇨병학회 2024 Diabetes and Metabolism Journal Vol.48 No.1

Insulin resistance has been regarded as a hallmark of diabetes heart disease (DHD). Numerous studies have shown that insulin resistance can affect blood circulation and myocardium, which indirectly cause cardiac hypertrophy and ventricular remodeling, participating in the pathogenesis of DHD. Meanwhile, hyperinsulinemia, hyperglycemia, and hyperlipidemia associated with insulin resistance can directly impair the metabolism and function of the heart. Targeting insulin resistance is a potential therapeutic strategy for the prevention of DHD. Currently, the role of insulin resistance in the pathogenic development of DHD is still under active research, as the pathological roles involved are complex and not yet fully understood, and the related therapeutic approaches are not well developed. In this review, we describe insulin resistance and add recent advances in the major pathological and physiological changes and underlying mechanisms by which insulin resistance leads to myocardial remodeling and dysfunction in the diabetic heart, including exosomal dysfunction, ferroptosis, and epigenetic factors. In addition, we discuss potential therapeutic approaches to improve insulin resistance and accelerate the development of cardiovascular protection drugs.

Rationally Designed Carbon Fiber@NiCo2O4@Polypyrrole Core-Shell Nanowire Array for High-Performance Supercapacitor Electrodes

Tingting Chen,Yong Fan,Guangning Wang,Jing Zhang,Huixin Chuo,Ruixiao Yang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.2

The composite supercapacitor electrodes were rationally fabricated by facile electrochemical deposition of polypyrrole (PPy) on NiCo2O4 nanowire arrays which were grown radially on carbon fiber (CF). When used as electrodes in supercapacitors, the composite nanostructures demonstrated prominent electrochemical performances with a high areal capacitance (1.44 F/cm2 at a current density of 2 mA/cm2 ), a good rate capability (80.5% when the current density increases from 2 mA/cm2 to 20 mA/cm2 ), and a good cycling ability (85% of the initial specific capacitance remained after 5000 cycles at a high current density of 10 mA/cm2 ). The excellent electrochemical performance of NiCo2O4@PPy nanostructures can be mainly ascribed to the good electrical conductivity of PPy, the enhanced adherent force between electrode materials and CF to hold the electrode fragments together by means of NiCo2O4 nanowires, the short ion diffusion pathway in ordered porous NiCo2O4 nanowires and the three-dimensional nanostructures.

Three-dimensional Microstructure Characterization of Loess from South Jingyang Plateau, China

( Tingting Wei ),( Wen Fan ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

The loess collapsibility and permeability are primarily controlled by the microstructure. This microstructural investigation of loess (L1 and S2) on the Loess Plateau in China is based on X-ray micro-computed tomography. The 3D microstructural features of particles and pores are quantitatively studied by analyzing statistical parameters. A total of 92% of the particles have sphericity that lies in the range between 0.5 and 0.9, the aspect ratio of 93% particles is between 0.3-0.7. 67% of the particles are oriented between 0°- 45° (the angle between the long axis of the grain and the horizontal plane). Loess exhibits complex pore structures and obvious anisotropy, as reflected by dense networks, wide pore size ranges and different pore throat radii and frequencies at different dip angles. From L1 to S2, the structure tends to become more compact, the pore size tends to decrease, and the connectivity tends to weaken. Pore structure, which provides space for water movement, has a profound influence on the mechanical behavior of soil, and the relationship between permeability and pore structure is discussed. The results demonstrate the positive role that the pore (>13 μm) proportion, pore connectivity and pore throat radius play in permeability. Both the pore throat radius and the permeability coefficient are greater in the vertical direction than in the horizontal direction, implying a large pore throat has a greater effect on water migration than that of multiple small pore throats.

Backbone Cyclization of Flavin Mononucleotide-Based Fluorescent Protein Increases Fluorescence and Stability

Lin Tingting,Ge Yuanyuan,Gao Qing,Zhang Di,Chen Xiaofeng,Hu Yafang,Fan Jun 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.12

Flavin mononucleotide-binding proteins or domains emit cyan-green fluorescence under aerobic and anaerobic conditions, but relatively low fluorescence and less thermostability limit their application as reporters. In this work, we incorporated the codon-optimized fluorescent protein from Chlamydomonas reinhardtii with two different linkers independently into the redox-responsive split intein construct, overexpressed the precursors in hyperoxic Escherichia coli SHuffle T7 strain, and cyclized the target proteins in vitro in the presence of the reducing agent. Compared with the purified linear protein, the cyclic protein with the short linker displayed enhanced fluorescence. In contrast, cyclized protein with incorporation of the long linker including the myc-tag and human rhinovirus 3C protease cleavable sequence emitted slightly increased fluorescence compared with the protein linearized with the protease cleavage. The cyclic protein with the short linker also exhibited increased thermal stability and exopeptidase resistance. Moreover, induction of the target proteins in an oxygen-deficient culture rendered fluorescent E. coli BL21 (DE3) cells brighter than those overexpressing the linear construct. Thus, the cyclic reporter can hopefully be used in certain thermophilic anaerobes.

Research on visual image design and Communication of Peking Opera elements in the New Media Era

Jing Tingting,Fan Qiangqiang 한국콘텐츠학회 2021 한국콘텐츠학회 ICCC 논문집 Vol.2021 No.12

The effect of crash pulse on occupant injury in frontal coach collisions

Sun Tingting,Xiong Xin,Zheng Zhuan,Shi Xiaolong,Fan Jianwei 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.11

The purpose of this study is to reveal the effect of different acceleration curves on occupant injury risk in the frontal collision of coaches. Based on characteristics of frontal crash acceleration curves, the influence of characteristic parameters on occupant injury was studied using a two-factor variance analysis method. The finite element-rigid body coupling method was used to establish a coupled simulation for the dummy and the sled and evaluate differences in the effects on occupant injury between the acceleration curves of four different coaches and the acceleration envelope of the ECE R80 standard. Results indicate that the upper limit of the simplified curve has the greatest influence on occupant injury and it displays a positive correlation. The acceleration curve stipulated by ECE R80 is too idealized, which may lead to inadequacies in safety protection capability in vehicle and seat design.

Variable Impedance Control of Cable Actuated Continuum Manipulators

Guangping He,Yanan Fan,Tingting Su,Lei Zhao,Quanliang Zhao 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.7

Continuum manipulators are a class of special compliant robots that have important potential applications in the field of human-machine interactive operations, or work in cluttered and constrained environments. In these application scenarios, the most popular operation tasks are those with coupling force-position constraints. To simultaneously stabilize the desired operation force and the position of the manipulator, variable impedance control issues of the cable driven continuum manipulators are investigated in this paper. On the basis of constructing a novelLyapunov function, a variable impedance control law is presented and the stability of the closed-loop system has also been analyzed. Then the operation space variable impedance control for a single segment cable driven continuum manipulator is realized by the aid of a pseudo-rigid-body model. Some numerical simulations also demonstrate the stability of the variable impedance control system.

Preparation of Monascus-fermented ginkgo seeds: optimization of fermentation parameters and evaluation of bioactivity

Wu Zhihao,Miao Wen,Yang Yuhan,Fan Gongjian,Wu Caie,Li Tingting,Xie Chunyan,Shen Dongbei 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.6

In this study, a high monacolin K yield was achieved through solid-state fermentation of Ginkgo biloba seeds. Monascus purpureus suspension made from red yeast rice was used as spore inoculum. Fermentation conditions in solid-state fermentation were optimized using response surface methodology, and the optimal conditions for the maximum monacolin K yield (17.71 ± 1.57 mg/g) were 0.22% ammonium sulfate, 0.34% ammonium chloride, 0.05% magnesium sulfate, fermentation time of 12 days, inoculation volume of 11%, and temperature of 27 °C. The total phenolic content of Monascus-fermented ginkgo seeds attained 9.67 mg GAE/g, 4.88-fold higher than that of unfermented ginkgo seeds. The scavenging abilities of DPPH and ABTS free radicals increased to 9.79 mg TE/g and 13.92 mg TE/g, respectively. These findings highlight the importance of investigating the optimal fermentation conditions for maximum monacolin K yield and the utilization value of ginkgo seed as fermentation substrate for higher bioactivities.

Polymorphisms in the uncoupling protein 3 gene and their associations with feed efficiency in chickens

Jin, Sihua,Yang, Lei,He, Tingting,Fan, Xinfeng,Wang, Yiqiu,Ge, Kai,Geng, Zhaoyu Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.9

Objective: The uncoupling protein 3 (UCP3) is a member of the mitochondrial anion carrier superfamily and has crucial effects on growth and feed efficiency in many species. Therefore, the objective of the present study was to examine the association of polymorphisms in the UCP3 gene with feed efficiency in meat-type chickens. Methods: Six single nucleotide polymorphisms (SNPs) of the UCP3 gene were chosen to be genotyped using matrix-assisted laser desorption-ionization time-of-flight mass spectrometry in meat-type chicken populations with 724 birds in total. Body weight at 49 (BW49) and 70 days of age (BW70) and feed intake (FI) in the interval were collected, then body weight gain (BWG) and feed conversion ratio (FCR) were calculated individually. Results: One SNP with a low minor allele frequency (<1%) was removed by quality control and data filtering. The results showed that rs13997809 of UCP3 was significantly associated with BWG and FCR (p<0.05), and that rs13997811 had significant effects on BW70 and BWG (p<0.05). Rs13997812 of UCP3 was strongly associated with BW70, FI, and FCR (p<0.05). Furthermore, individuals with AA genotype of rs13997809 had significantly higher BWG and lower FCR (p<0.05) than those with AT genotype. The GG individuals showed strongly higher BW70 and BWG than AA birds in rs13997811 (p<0.05). Birds with the TT genotype of rs13997812 had significantly greater BW70 and lower FCR compared with the CT birds (p<0.05). In addition, the TAC haplotype based on rs13997809, rs13997811, and rs13997812 showed significant effects on BW70, FI, and FCR (p<0.05). Conclusion: Our results therefore demonstrate important roles for UCP3 polymorphisms in growth and feed efficiency that might be used in meat-type chicken breeding programs.