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[Keynote Speeches] RETENTION AIDS:FROM ART TO SCIENCE
Theo G.M,van de Ven 한국펄프·종이공학회 1999 한국펄프종이학회 기타 간행물 Vol.- No.-
Our knowledge about the mechanisms by which retention aids function in wet-end papermaking has been increasing rapidly. Although originally many retention aids were introduced without little understanding of how they act, nowadays a clear scientific understanding is emerging. We can say that the use of retention aids has passed from an art which depended much on experience and intuition, to a science, which involves the principles of colloid and polymer science. Various examples of our increased understanding of PEO-based retention. aids, cationic. poly-and microparticulate retention aid systems are being discussed.
Functional Magnetic Resonance Imaging of Motor Cortex Activation in Schizophrenia
이효종,Adrian Preda,Judith M. Ford,Daniel H. Mathalon,David B. Keator,Theo G.M. van Erp,Jessica A. Turner,Steven G. Potkin 대한의학회 2015 Journal of Korean medical science Vol.30 No.5
Previous fMRI studies of sensorimotor activation in schizophrenia have found in some cases hypoactivity, no difference, or hyperactivity when comparing patients with controls; similar disagreement exists in studies of motor laterality. In this multi-site fMRI study of a sensorimotor task in individuals with chronic schizophrenia and matched healthy controls, subjects responded with a right-handed finger press to an irregularly flashing visual checker board. The analysis includes eighty-five subjects with schizophrenia diagnosed according to the DSM-IV criteria and eighty-six healthy volunteer subjects. Voxel-wise statistical parametric maps were generated for each subject and analyzed for group differences; the percent Blood Oxygenation Level Dependent (BOLD) signal changes were also calculated over predefined anatomical regions of the primary sensory, motor, and visual cortex. Both healthy controls and subjects with schizophrenia showed strongly lateralized activation in the precentral gyrus, inferior frontal gyrus, and inferior parietal lobule, and strong activations in the visual cortex. There were no significant differences between subjects with schizophrenia and controls in this multi-site fMRI study. Furthermore, there was no significant difference in laterality found between healthy controls and schizophrenic subjects. This study can serve as a baseline measurement of schizophrenic dysfunction in other cognitive processes.
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Guadalupe, Tulio,Mathias, Samuel R.,vanErp, Theo G. M.,Whelan, Christopher D.,Zwiers, Marcel P.,Abe, Yoshinari,Abramovic, Lucija,Agartz, Ingrid,Andreassen, Ole A.,Arias-Vá,squez, Alejandro,Aribi Springer US 2017 Brain imaging and behavior Vol.11 No.5
<P>The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors is still controversial. Here we present the largest ever analysis of subcortical brain asymmetries, in a harmonized multi-site study using meta-analysis methods. Volumetric asymmetry of seven subcortical structures was assessed in 15,847 MRI scans from 52 datasets worldwide. There were sex differences in the asymmetry of the globus pallidus and putamen. Heritability estimates, derived from 1170 subjects belonging to 71 extended pedigrees, revealed that additive genetic factors influenced the asymmetry of these two structures and that of the hippocampus and thalamus. Handedness had no detectable effect on subcortical asymmetries, even in this unprecedented sample size, but the asymmetry of the putamen varied with age. Genetic drivers of asymmetry in the hippocampus, thalamus and basal ganglia may affect variability in human cognition, including susceptibility to psychiatric disorders.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s11682-016-9629-z) contains supplementary material, which is available to authorized users.</P>
A deposition efficiency model for fiber–filler flocculation by microparticle retention system
Byoung-Uk Cho,Gil Garnier,Theo G.M. van de Ven,Michel Perrier 한국공업화학회 2009 Journal of Industrial and Engineering Chemistry Vol.15 No.2
A deposition efficiency model was developed in order to predict the effect of the dosage of retention aids (polymer and bentonite) on filler retention and validated with a pilot machine trial. The deposition efficiency is a function of the surface coverage of adsorbed and transferred polymer on solids (fiber and filler) and the surface coverage of microparticles on the polymer-adsorbed layer. The model includes the effect of bimodal particles (i.e., fiber and filler) and the polymer transfer from fiber to filler. In addition, the interaction between bare surfaces was included in the model and different bond strength of each interaction was considered. It was shown that an increase in the deposition efficiency leads to an increase in the filler retention. The dosage of CPAM is more predominant variable affecting deposition efficiency and thus filler retention than that of bentonite. Crown Copyright 2009 Published by Elsevier B.V. on behalf of The Korean Society of Industrial and Engineering Chemistry. All rights reserved.
Glover, Gary H.,Mueller, Bryon A.,Turner, Jessica A.,van Erp, Theo G.M.,Liu, Thomas T.,Greve, Douglas N.,Voyvodic, James T.,Rasmussen, Jerod,Brown, Gregory G.,Keator, David B.,Calhoun, Vince D.,Lee, H Wiley Subscription Services, Inc., A Wiley Company 2012 JOURNAL OF MAGNETIC RESONANCE IMAGING Vol.36 No.1
<P><B>Abstract</B></P><P>This report provides practical recommendations for the design and execution of multicenter functional MRI (MC‐fMRI) studies based on the collective experience of the Function Biomedical Informatics Research Network (FBIRN). The study was inspired by many requests from the fMRI community to FBIRN group members for advice on how to conduct MC‐fMRI studies. The introduction briefly discusses the advantages and complexities of MC‐fMRI studies. Prerequisites for MC‐fMRI studies are addressed before delving into the practical aspects of carefully and efficiently setting up a MC‐fMRI study. Practical multisite aspects include: (i) establishing and verifying scan parameters including scanner types and magnetic fields, (ii) establishing and monitoring of a scanner quality program, (iii) developing task paradigms and scan session documentation, (iv) establishing clinical and scanner training to ensure consistency over time, (v) developing means for uploading, storing, and monitoring of imaging and other data, (vi) the use of a traveling fMRI expert, and (vii) collectively analyzing imaging data and disseminating results. We conclude that when MC‐fMRI studies are organized well with careful attention to unification of hardware, software and procedural aspects, the process can be a highly effective means for accessing a desired participant demographics while accelerating scientific discovery. J. Magn. Reson. Imaging 2012;36:39–54. © 2012 Wiley Periodicals, Inc.</P>