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Rajendran Vijayabharathi,Per Bruheim,Trygve Andreassen,Duraisamy Senthil Raja,Palanisamy Bruntha Devi,Sathyaseelan Sathyabama,Venkatesan Brindha Priyadarisini 한국미생물학회 2011 The journal of microbiology Vol.49 No.6
A new actinomycete strain, isolated from humus soils in the Western Ghats, was found to be an efficient pigment producer. The strain, designated AAA5, was identified as a putative Streptomyces aurantiacus strain based on cultural properties, morphology, carbon source utilization, and analysis of the 16S rRNA gene. The strain produced a reddish-brown pigmented compound during the secondary metabolites phase. A yellow compound was derived from the extracted pigment and was identified as the quinone-related antibiotic resistomycin based on ultraviolet–visible spectrophotometry, fourier transform infrared spectroscopy, liquid chromatography and mass spectroscopy, and nuclear magnetic resonance analyses. The AAA5 strain was found to produce large quantities of resistomycin (52.5 mg/L). It showed potent cytotoxic activity against cell lines viz. HepG2 (hepatic carcinoma) and HeLa (cervical carcinoma) in vitro, with growth inhibition (GI_50) of 0.006 and 0.005 μg/ml, respectively. The strain also exhibited broad antimicrobial activities against both Gram-positive and Gram-negative bacteria. Therefore, AAA5 may have great potential as an industrial resistomycin-producing strain.
Soil properties after forest rehabilitation by planting teak and mahogany in Java, Indonesia
Cicik Udayana,Christina Skarpe,Svein Ø. Solberg,Karen M. Mathisen,Harry P. Andreassen 한국산림과학회 2019 Forest Science And Technology Vol.15 No.4
We studied how rehabilitation of forests in Indonesia by planting teak, Tectona grandis (L.f.), and mahogany, Swietenia macrophylla (King), was associated with soil pH, organic matter, total nitrogen, total phosphorus, and total potassium. We also analyzed how soil properties and the environment (i.e. soil order, altitude, stand age) were associated with succession and compared rehabilitated stands with native forests. We found higher pH in teak compared to mahogany stands. The soil pH was lowest in the oldest stands (>70 years). Herb density was positively related to pH and to phosphorus, while density of seedlings and woody plants was positively related to nitrogen, potassium and phosphorus. Tree and herb species richness and tree density were positively associated with Oxisols, but negatively related to the proportion of native herbs. Species richness of herbs and density of seedlings decreased with time since rehabilitation, whereas species richness of woody plants increased. The proportion of native herbs and seedlings increased with stand age. We found few differences in soils between the planted stands and native forest. Our results demonstrated that successional vegetation of rehabilitated forests may play an important role in maintaining soil properties associated with soil order.
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Guadalupe, Tulio,Mathias, Samuel R.,vanErp, Theo G. M.,Whelan, Christopher D.,Zwiers, Marcel P.,Abe, Yoshinari,Abramovic, Lucija,Agartz, Ingrid,Andreassen, Ole A.,Arias-Vá,squez, Alejandro,Aribi Springer US 2017 Brain imaging and behavior Vol.11 No.5
<P>The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors is still controversial. Here we present the largest ever analysis of subcortical brain asymmetries, in a harmonized multi-site study using meta-analysis methods. Volumetric asymmetry of seven subcortical structures was assessed in 15,847 MRI scans from 52 datasets worldwide. There were sex differences in the asymmetry of the globus pallidus and putamen. Heritability estimates, derived from 1170 subjects belonging to 71 extended pedigrees, revealed that additive genetic factors influenced the asymmetry of these two structures and that of the hippocampus and thalamus. Handedness had no detectable effect on subcortical asymmetries, even in this unprecedented sample size, but the asymmetry of the putamen varied with age. Genetic drivers of asymmetry in the hippocampus, thalamus and basal ganglia may affect variability in human cognition, including susceptibility to psychiatric disorders.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1007/s11682-016-9629-z) contains supplementary material, which is available to authorized users.</P>