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등온반응기와 단열반응기 조합으로 구성된 0.25 MW급 메탄합성 파일롯 공정 운전특성
김수현(Suhyun Kim),유영돈(Youngdon Yoo),강석환(Sukhwan Kang),류재홍(Jaehong Ryu),김진호(Jinho Kim),김문현(Munhyun Kim),고동준(Dongjun Koh),이현정(Hyunjung Lee),김광준(Gwangjun Kim),김형택(Hyungtaek Kim) 한국청정기술학회 2013 청정기술 Vol.19 No.2
본 연구에서는 등온반응기와 단열반응기로 구성된 0.25 MW 메탄합성 파일롯 공정 실험을 통한 운전 특성을 분석하였다. 등온반응기는 메탄합성 반응을 통해 발생하는 열을 포화수의 유량과 압력을 통해 강제적으로 제어할 수 있는 반응기로 등온반응기와 단열반응기를 조합할 경우 기존 단열반응기만으로 구성된 메탄합성 공정에 비해 반응기 개수를 줄일 수 있다. 또한 합성가스 재순환이 불필요하기 때문에 단열반응기 조합으로 구성된 메탄합성 공정에서 비용의 약 15~20%를 차지하는 재순환 압축기를 제거할 수 있다. 등온반응기로 유입되는 합성가스의 H2/CO 비가 3보다 낮은 경우에는 튜브에 충진된 촉매에 탄소 침적 현상이 일어나 반응기의 차압이 증가하였으며, H₂/CO 비가 3으로 공급되는 경우에는 탄소 침적 현상이 일어나지 않고 메탄합성 반응이 안정적으로 유지되어 CO 전환율 99% 이상, CH₄ 선택도 97% 이상, CH₄ 생산성 최대 695 ml/h·-cat를 얻을 수 있었다. In this study, we analyzed the operational characteristics of a 0.25 MW methanation pilot plant. Isothermal reactor controled the heat released from methanation reaction by saturated water in shell side. Methanation process consisting of isothermal reactor and adiabatic reactor had advantages with no recycle compressor and more less reactors compared with methanation process with only adiabatic reactors. In case that H2/CO ratio of syngas was under 3, carbon deposition occurred on catalyst in tube side of isothermal reactor and the pressure of reactors increased. In case that H₂/CO ratio was maintained around 3, no carbon deposition on catalyst in tube side of isothermal reactor was found by monitoring the differential pressure of reactors and by measuring the differential pressure of several of tubes filled with catalyst before and after operating. It was shown that CO conversion and CH₄ selectivity were over 99, 97%, respectively, and the maximum CH₄ productivity was 695 ml/h·g-cat.
Kim, Seoungkyun,Kim, Manse,Jung, Secheon,Kwon, Kiyoon,Park, Junyong,Kim, Sukhwan,Kwon, Inchan,Tae, Giyoong Elsevier 2019 Journal of controlled release Vol.309 No.-
<P><B>Abstract</B></P> <P>Therapeutic proteins are indispensable in the treatment of various human diseases. Despite the many benefits of therapeutic proteins, they also exhibit diverse side effects. Therefore, reducing unwanted side effects of therapeutic proteins as well as enhancing their therapeutic efficacy are very important in developing therapeutic proteins. Urate oxidase (UOX) is a therapeutic enzyme that catalyzes the conversion of uric acid (UA) into a soluble metabolite, and it is used clinically for the treatment of hyperuricemia. Since UA degradation by UOX generates H<SUB>2</SUB>O<SUB>2</SUB> (a cytotoxic side product), UOX was co-delivered with catalase-mimic nanoparticles (AuNPs) using biocompatible pluronic-based nanocarriers (NCs) to effectively reduce H<SUB>2</SUB>O<SUB>2</SUB>-associated toxicity in cultured cells and to enhance UA degradation efficiency <I>in vivo</I>. Simple temperature-dependent size changes of NCs allowed co-encapsulation of both UOX and AuNPs at a high loading efficiency without compromising critical properties, resulting in efficient modulation of a mixing ratio of UOX and AuNPs encapsulated in NCs. Co-localizing UOX and AuNPs in the NCs led to enhanced UA degradation and H<SUB>2</SUB>O<SUB>2</SUB> removal <I>in vitro</I>, leading to a great reduction in H<SUB>2</SUB>O<SUB>2</SUB>-associated cytotoxicity compared with UOX alone or a free mixture of UOX and AuNPs. Furthermore, we demonstrated that co-delivery of UOX and AuNPs using NCs significantly improves <I>in vivo</I> UA degradation compared to simple co-injection of free UOX and AuNPs. More broadly, we showed that biocompatible pluronic-based nanocarriers can be used to deliver a target therapeutic protein along with its toxicity-eliminating agent in order to reduce side effects and enhance efficacy.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Sukhwan Choi,Hyun-Sik Kim,Seungchul Jung,Si-Duk Sung,Young-Sub Yuk,Hyuck-Sang Yim,Yoonjae Shin,Jun-Ho Cheon,Changyong Ahn,Taekseung Kim,Kim, Yongki Brave,Gyu-Hyeong Cho IEEE 2014 IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS PART 1 R Vol.61 No.11
<P>A PRAM write driver with an auto-scaling overdrive method is presented. The proposed overdrive method significantly reduces the rise time of the cell-current pulse for bit-line parasitic components of 3 pF and 6 k Ω, and it lowers the complexity of the overdrive control using an adaptive charge amplification technique. A rise time of less than 15 ns is achieved and shortened up to 4.7 times, and the total write-throughput is increased. The rise time is reduced consistently for all levels of the target-current by the auto-scaling effect. Therefore, cell heating control becomes more linear in program-and-verify (PNV) operation. Due to its simple adding-on structure, it is easily compatible with a conventional write driver. A prototype chip was implemented using a 0.18- μm CMOS process. It is also applicable to smaller-scale technology.</P>
김민균(Kim Mingyun),전석환(Jeon Sukhwan),이주원(Lee Joowon),홍성은(Hong Sungen),방준일(Bang Joonil),김화종(Kim Hwajong) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2
본 논문에서는 버섯 이미지의 분류를 위하여 CNN 기반 모델(LeNet, ResNet50, ResNet152, MobileNet)을 사용하였다. 본 연구에 사용된 데이터는 Kaggle에 데이터 세트를 이용하였다. 정확도를 높이기 위해 데이터 전처리 작업과 4개 정도의 모델들을 활용해 보았다. 여러 모델들을 이용하여 학습하였을 때, 분류 예측 정확도는 ResNet, MobileNet에서 75% 정도가 나온 것을 확인할 수 있었다. 더 나아가 이렇게 학습된 분류 모델을 활용하여 독버섯으로 인한 사고가 방지되길 기대한다.
김석환(Sukhwan Kim),신동원(Dong Won Shin) 한국정보통신학회 2021 한국정보통신학회 종합학술대회 논문집 Vol.25 No.2
소각로에 반입된 생활폐기물은 고온으로 소각되고 잔여물인 소각재가 발생하게 된다. 소각재에는 바닥재와 비산재가 있으며, 소각로에 전체 반입되는 양에 약 16.5%정도의 소각재(바닥재, 비산재)가 발생한다. 현재 기존 매립되는 증가하는 소각재의 양은 기존 매립장의 매립 연한을 감소시키고 신규매립장 건립 부담이 증가하고 있다. 또한 주변환경 피해(임야절취, 악취, 수질오염 등)를 유발시키기도 한다. 따라서 본 연구에서는 생활폐기물 소각시설에서 발생하는 소각재의 재활용 활성화를 통해 소각재 문제를 해결하는 방안을 제시하고자 한다. 세부적으로 기술적 재활용 방안으로 토공재료 및 콘크리트 제품 등을 생산하여 재활용 방안을 제시하며, 정부 및 각 지자체에서는 소각재의 재활용 활성화를 위하여 폐기물 관리법 등 관련법을 정비하고 재활용업체에 대한 인센티브 등 적극적인 제도적 지원 방안을 마련하여 소각재의 재활용 활성화할 것을 제안한다. A large amount of combustible household waste are incinerated on a large scale. Incineration ashes including flooring and scattering materials are generated in the incineration facilities. The incineration materials (flooring and scattering) are generated 16.5% of the total amount ashes brought into the incinerator. The amount of incineration materials decrease the landfill period of existing landfills and increase the needs for the construction of new landfills. This study introduces technical and institutional suggestions to solve increasing incineration ash problem by recycling them. As a technical recycling method, incineration materials can be recycled by producing earthwork materials and concrete products. In addition, the government and local governments will be able to promote recycling by improving related laws such as the Waste Management Act and by preparing active institutional support measures such as incentives for recycling companies for Green New Deal strategies.
김영동(Youngdong Kim),최선우(Sunwoo Choi),김석환(Sukhwan Kim),김상호(Sangho Kim),허준열(Junyoel Heo),이위로(Whero Lee),최상민(Sangmin Choi) 한국자동차공학회 2013 한국자동차공학회 학술대회 및 전시회 Vol.2013 No.11
This paper is the proposal about providing an optimal design specification by utilizing the analysis simulation in order to improve the dynamic comfort of seat. First, it is analyzed transmissibility of the model having excellent long-distance comfort in condition of the same vibration condition, and optimized specifications is proposed as DFSS approach to reduce the vibration transmissibility at high frequency. Final optimized SEAT index showed the effect of decreasing 6.5% compared to the current specification. In addition, the improved seat sample was confirmed that the performance was improved by SEAT index to figure measurement and subject evaluation.