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Min Young Park,Guusje Bonnema,Suhyung Park,Yong Pyo Lim 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07
For genetic mapping studies, biparental segregating populations are often useful, however recombination is limited, giving rise to large genomic regions under QTL, and one can only study alelles present in both parents. In Wageninegn UR, a core collection is being developed representing all Brassica rapa morphotypes and geographic origins. As most B. rapa accessions are heterozygous and heterogeneous, we started a project to fix the collection through microspore culture. The resulting Diversity Fixed Foundation Set will be an interesting resource for association mapping studies, which have as advantage that they present the allelec variation present in the collection, and for mapping studies recombination is increased. Nineteen accessions of eight subspecies of Brassica rapa were used for microspore culture to developdoubled haploid lines. Eight morphotypes were represented: 3 Chinese cabbage, 2 Chinese turnip cabbage, 3 Pak choi, 5 Turnip, 3 Broccolleto, 1 Mizuna, 1 Komatsuna and 1 Turnip greenfrom the 19acessions examined, embryos were obtained for 13, representing six subspecies (Komatsuna and Turnip Green had no response). The embryo yields differed significantly between these 13 accessions. We regenerated normal plants from 10 accessions that survived more than 4 weeks in the soil using microspore culture. Nine accessions flowered after 4 weeks vernalization at 5℃ and seeds were harvested from 5 accessions. From a Mizuna, we obtained 3791 seeds from one plant and total 7318 seeds were harvested from 5 accessions representing 4 subspecies(Chinese cabbage, Chinese turnip cabbage, Pak choi, Mizuna). At present, we carry out experiment for obtain more seeds and induce embryos from the other plant materials.
Park, Suhyung,Kim, Eung Yeop,Sohn, Chul-Ho,Park, Jaeseok IEEE 2017 IEEE transactions on medical imaging Vol.36 No.2
<P>Dynamic contrast-enhanced magnetic resonance angiography (DCE MRA) has been widely used as a clinical routine for diagnostic assessment of vascular morphology and hemodynamics. It requires high spatial and temporal resolution to capture rapid variation of DCE signals within a limited imaging time. Subtraction-based approaches are typically employed to selectively delineate arteries while eliminating unwanted background signals. Nevertheless, in the presence of subject motion with time, conventional subtraction approaches suffer from incomplete background suppression that impairs the detectability of arteries. In this work, we propose a novel, DCE MRA method that exploits subspace projection (SP) based angiogram separation for robust background suppression. A new, SP-based DCE signal model is introduced, in which images are decomposed into stationary background tissues, motion-induced artifacts, and DCE angiograms of interest. Constrained image reconstruction with sparsity priors is performed to project motion-induced artifacts onto the predefined subspace while extracting DCE angiograms of interest. Simulations and experimental studies validate that the proposed method outperforms existing techniques with increasing reduction factors in suppressing artifacts and noise.</P>
Adaptive self‐calibrating iterative GRAPPA reconstruction
Park, Suhyung,Park, Jaeseok Wiley Subscription Services, Inc., A Wiley Company 2012 Magnetic resonance in medicine Vol.67 No.6
<P><B>Abstract</B></P><P>Parallel magnetic resonance imaging in <I>k</I>‐space such as generalized auto‐calibrating partially parallel acquisition exploits spatial correlation among neighboring signals over multiple coils in calibration to estimate missing signals in reconstruction. It is often challenging to achieve accurate calibration information due to data corruption with noises and spatially varying correlation. The purpose of this work is to address these problems simultaneously by developing a new, adaptive iterative generalized auto‐calibrating partially parallel acquisition with dynamic self‐calibration. With increasing iterations, under a framework of the Kalman filter spatial correlation is estimated dynamically updating calibration signals in a measurement model and using fixed‐point state transition in a process model while missing signals outside the step‐varying calibration region are reconstructed, leading to adaptive self‐calibration and reconstruction. Noise statistic is incorporated in the Kalman filter models, yielding coil‐weighted de‐noising in reconstruction. Numerical and in vivo studies are performed, demonstrating that the proposed method yields highly accurate calibration and thus reduces artifacts and noises even at high acceleration. Magn Reson Med, 2011. © 2011 Wiley Periodicals, Inc.</P>
Park, Jaeseok,Park, Suhyung,Yeop Kim, Eung,Suh, Jin‐,Suck Wiley Subscription Services, Inc., A Wiley Company 2010 Magnetic resonance in medicine Vol.63 No.5
<P><B>Abstract</B></P><P>Conventional <I>T</I><SUB>2</SUB>‐weighted turbo/fast spin echo imaging is clinically accepted as the most sensitive method to detect brain lesions but generates a high signal intensity of cerebrospinal fluid (CSF), yielding diagnostic ambiguity for lesions close to CSF. Fluid‐attenuated inversion recovery can be an alternative, selectively eliminating CSF signals. However, a long time of inversion, which is required for CSF suppression, increases imaging time substantially and thereby limits spatial resolution. The purpose of this work is to develop a phase‐sensitive, dual‐acquisition, single‐slab, three‐dimensional, turbo/fast spin echo imaging, simultaneously achieving both conventional <I>T</I><SUB>2</SUB>‐weighted and fluid‐attenuated inversion recovery–like high‐resolution whole‐brain images in a single pulse sequence, without an apparent increase of imaging time. Dual acquisition in each time of repetition is performed, wherein an in phase between CSF and brain tissues is achieved in the first acquisition, while an opposed phase, which is established by a sequence of a long refocusing pulse train with variable flip angles, a composite flip‐down restore pulse train, and a short time of delay, is attained in the second acquisition. A CSF‐suppressed image is then reconstructed by weighted averaging the in‐ and opposed‐phase images. Numerical simulations and in vivo experiments are performed, demonstrating that this single pulse sequence may replace both conventional <I>T</I><SUB>2</SUB>‐weighted imaging and fluid‐attenuated inversion recovery. Magn Reson Med 63:1422–1430, 2010. © 2010 Wiley‐Liss, Inc.</P>
PID Auto Gain Tuning of DC motor using RLS
Daeyeol Yang,Suhyung Park,Bongseok Kim,Euntai Kim,Hyeongcheol Lee 대한전자공학회 2008 ICEIC:International Conference on Electronics, Inf Vol.1 No.1
It is difficult for gain tuning engineer to set gain value, because gain value is changeable according to distance and speed. In many case, engineer do not set the gain when it is dangerous to move object. So, We do DC motor modeling, root locus is satisfied to system stability. Because calculated gain has uncertainty, we remove it using RLS algorithm. This system finds gain values, and it sets values automatically. So, we obtained result of better performance. It is easy to operate many motors of humanlike robot. Results were explained in terms of advantage of this method. These experiments show that human-like robot engineer will use auto-gain tuning algorithm to many robots in the future.
Kim, Kangmin,Park, Suhyung,Park, Jeong Hwan,Cho, Won-Sang,Kim, Hyoun-Ee,Lee, Sung-Mi,Kim, Jeong Eun,Kang, Hyun-Seung,Jang, Tae-Sik The Korean Neurosurgical Society 2021 Journal of Korean neurosurgical society Vol.64 No.6
Objective : Biodegradable poly-L-lactic acid (PLLA) with a highly biocompatible surface via tantalum (Ta) ion implantation can be an innovative solution for the problems associated with current biodegradable stents. The purpose of this study is to develop a Taimplanted PLLA stent for clinical use and to investigate its biological performance capabilities. Methods : A series of in vitro and in vivo tests were used to assess the biological performance of bare and Ta-implanted PLLA stents. The re-endothelialization ability and thrombogenicity were examined through in vitro endothelial cell and platelet adhesion tests. An in vivo swine model was used to evaluate the effects of Ta ion implantation on subacute restenosis and thrombosis. Angiographic and histologic evaluations were conducted at one, two and three months post-treatment. Results : The Ta-implanted PLLA stent was successfully fabricated, exhibiting a smooth surface morphology and modified layer integration. After Ta ion implantation, the surface properties were more favorable for rapid endothelialization and for less platelet attachment compared to the bare PLLA stent. In an in vivo animal test, follow-up angiography showed no evidence of in-stent stenosis in either group. In a microscopic histologic examination, luminal thrombus formation was significantly suppressed in the Ta-implanted PLLA stent group according to the 2-month follow-up assessment (21.2% vs. 63.9%, p=0.005). Cells positive for CD 68, a marker for the monocyte lineage, were less frequently identified around the Ta-implanted PLLA stent in the 1-month follow-up assessments. Conclusion : The use of a Ta-implanted PLLA stent appears to promote re-endothelialization and anti-thrombogenicity.