Parenchymal-sparing anatomical hepatectomy based on portal ramification of the right anterior section: A prospective multicenter experience with short-term outcomes

Truong Giang Nguyen,Thanh Khiem Nguyen,Ham Hoi Nguyen,Hong Son Trinh,Tuan Hiep Luong,Minh Trong Nguyen,Van Duy Le,Hai Dang Do,Kieu Hung Nguyen,Van Minh Do,Quang Huy Tran,Cuong Thinh Nguyen 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1

Backgrounds/Aims: Parenchymal-sparing anatomical hepatectomy (Ps–AH) based on portal ramification of the right anterior section (RAS) is a new technique to avoid unnecessarily transecting too much liver parenchyma, especially in cases of major anatomical hepatectomy. Methods: We prospectively assessed 26 patients with primary hepatic malignancies having undergone major Ps–AH based on portal ramification of the RAS from August 2018 to August 2022 (48 months). The perioperative indications, clinical data, intra-operative index, pathological postoperative specimens, postoperative complications, and follow-up results were retrospectively evaluated. Results: Among the 26 patients analyzed, there was just one case that had intrahepatic cholangiocarcinoma The preoperative level of α– Fetoprotein was 25.2 ng/mL. All cases (100%) had Child–Pugh A liver function preoperatively. The ventral/dorsal RAS was preserved in 19 and 7 patients, respectively. The mean surgical margin was 6.2 mm. The mean surgical time was 228.5 minutes, while the mean blood loss was 255 mL. In pathology, 5 cases (19.2%) had microvascular invasion, and in the group of HCC patients, 92% of all cases had moderate or poor tumor differentiation. Six cases (23.1%) of postoperative complications were graded over III according to the Clavien–Dindo system, including in three patients resistant ascites or intra-abdominal abscess that required intervention. Conclusions: Parenchymal-sparing anatomical hepatectomy based on portal ramification of the RAS to achieve R0-resection was safe and effective, with favorable short-term outcomes. This technique can be used widely in clinical practice.

Metagenomic investigation of the seasonal distribution of bacterial community and antibiotic‑resistant genes in Day River Downstream, Ninh Binh, Vietnam

Nguyen Son Giang,Raza Shahbaz,Ta Loan Thi,Le Lan-Anh Thi,Ho Cuong Tu,Unno Tatsuya 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.2

In this study, we use high-throughput sequencing-based metagenomic methods to investigate the differences in seasonal structures of the bacterial community and the abundance and diversity of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in both shrimp ponds and river water samples downstream of the Day River, Ninh Binh, Vietnam. The structure of the central bacterial community, ARGs, and MGEs was found to be regardless of the seasons and locations. The predominant phyla found in all samples was Proteobacteria, Bacteroidetes, and Actinobacteria. Multi-drug resistance (MDR) genes and transposases are the most dominant ARG types and MGEs, respectively. Our data showed a higher abundance of bacterial communities, ARGs, and MGEs in the river water during the rainy season. There is a significant correlation between the abundance of ARGs, MGEs, and environmental factors. Our results indicate that water environments containing ARGs/MGEs carrying bacteria pose a risk to shrimp and human health, especially during the rainfall-polluted water season.

Seasonal Change of Sediment Microbial Communities and Methane Emission in Young and Old Mangrove Forests in Xuan Thuy National Park

( Cuong Tu Ho ),( Unno Tatsuya ),( Son Giang Nguyen ),( Thi-hanh Nguyen ),( Son Truong Dinh ),( Son Tho Le ),( Thi-minh-hanh Pham ) 한국미생물생명공학회 2024 Journal of microbiology and biotechnology Vol.34 No.3

Microbial communities in mangrove forests have recently been intensively investigated to explain the ecosystem function of mangroves. In this study, the soil microbial communities under young (< 11 years-old) and old ( >17 years-old) mangroves have been studied during dry and wet seasons. In addition, biogeochemical properties of sediments and methane emission from the two different mangrove ages were measured. The results showed that young and old mangrove soil microbial communities were significantly different on both seasons. Seasons seem to affect microbial communities more than the mangrove age does. Proteobacteria and Chloroflexi were two top abundant phyla showing >15%. Physio-chemical properties of sediment samples showed no significant difference between mangrove ages, seasons, nor depth levels, except for TOC showing significant difference between the two seasons. The methane emission rates from the mangroves varied depending on seasons and ages of the mangrove. However, this did not show significant correlation with the microbial community shifts, suggesting that abundance of methanogens was not the driving factor for mangrove soil microbial communities.

Phytoplankton composition in intensive shrimp ponds in Bac Lieu province, Vietnam

Nguyen Thi Kim Lien,Phan Thi Cam Tu,Vo Nam Son,Huynh Truong Giang 한국수산과학회 2023 Fisheries and Aquatic Sciences Vol.26 No.8

Algal overgrowth in shrimp culture ponds can affect the quality of the aquatic environment, thereby adversely affecting the shrimp and causing economic losses. The objective of this study was to evaluate the variation in phytoplankton composition in intensive shrimp ponds in Bac Lieu province, Vietnam. Phytoplankton samples were collected in three black tiger shrimp (Penaeus monodon) ponds and three whiteleg shrimp (Litopenaeus vannamei) ponds. The collected data were analyzed using SPSS and canonical correlation analysis softwares. In total, 75 species of phytoplankton were recorded in black tiger shrimp ponds and 64 species in whiteleg shrimp ponds. Diatoms had the highest species diversity with 29–30 species (39%–47%), followed by green algae with 9–19 species (14%–25%); species numbers of other phyla varied from 5–12 (8%–16%). The total number of phytoplankton species throughout the study varied from 34–50 species. Algal density was relatively high and ranged from 497,091–2,229,500 ind./L and 1,301,134–2,237,758 ind./L in black tiger shrimp and whiteleg shrimp ponds, respectively. The diatom density tended to increase during the final stage of the production cycle in black tiger shrimp ponds. Blue-green algae and dinoflagellates also increased in abundance at the end of the cycle, which can affect shrimp growth. Diatoms were significantly positively correlated with pH, salinity, total ammonia nitrogen, and nitrate (NO3 –) concentrations (p < 0.05). Blue-green algae and dinoflagellates were positively correlated with salinity, phosphate (PO4 3–), and NO3 –. Algal species diversity was lower in the whiteleg shrimp ponds than in the black tiger shrimp ponds. Several dominant algal genera were recorded in the shrimp ponds, including Nannochloropsis, Gyrosigma, Chaetoceros, Alexandrium, and Microcystis. The results of this study provide basic data for further investigations, and they contribute to the management of algae in brackish-water shrimp ponds.

Exposure to Tobacco Advertising and Promotion among School Children Aged 13-15 in Vietnam - an Overview from GYTS 2014

Tran, Khanh Long,Phung, Xuan Son,Kim, Bao Giang,Phan, Thi Hai,Doan, Thi Thu Huyen,Luong, Ngoc Khue,Pham, Thi Quynh Nga,Nguyen, Tuan Lam,Hoang, Van Minh,Le, Thi Thanh Huong Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1

Evidence shows that tobacco advertising and promotion activities may increase tobacco consumption and usage, especially in youth. Despite the regulation on prohibiting advertisement of any tobacco product, tobacco advertisement and promotion activities are still common in Vietnam. This article presents current exposure to tobacco advertising and promotion (TAP) among school children aged 13 to 15 years in Vietnam in 2014 and potential influencing factors. Data from the Global Youth Tobacco Survey 2014 in Vietnam covering 3,430 school aged children were used. Both descriptive and analytical statistics were carried out with Stata 13 statistical software. Binary logistic regression was applied to explain the exposure to TAP among youth and examine relationships with individual factors. A significance level of p<0.05 and sampling weights were used in all of the computations. In the past 30 days, 48.6% of the students experienced exposure to at least 1 type of tobacco advertising or promotion. Wearing or otherwise using products related to tobacco was the most exposure TAP type reported by students (22.3%). The internet (22.1), points of sales (19.2) and social events (11.5) were three places that students aged 13-15 frequently were exposed to TAP. Binary logistic results showed that gender (female vs male) (OR = 0.61, 95%CI: 0.52 - 0.71), susceptibility to smoking (OR = 2.12, 95%CI: 1.53 - 2.92), closest friends' smoked (OR = 1.43, 95%CI: 1.2 - 1.7) and parents smoking status (OR = 2.83, 95%CI: 1.6 - 5.01) were significantly associated with TAP exposure among school-aged children. The research findings should contribute to effective implementation of measures for preventing and controlling tobacco use among students aged 13-15 in Viet Nam.

Study Design for the 2016 Baseline Survey of a Health System Strengthening Project in Quoc Oai District, Hanoi, Vietnam

Van Minh Hoang,오주환,Bao Ngoc Nguyen,Le Minh Dat,이종구,Thi Giang Huong Tran,Van Huy Nguyen,이승표,방경숙,조영태,김선영,이화영,Quang Cuong Le,Narshil Choi,Thai Son Dinh,Ngoc Hoat Luu 대한의학회 2019 Journal of Korean medical science Vol.34 No.5

Background: In order to provide essential scientific evidence on the population's health status and social health determinants as well as the current capacity of the health care system in Vietnam to health policy makers and managers, Vietnam Ministry of Health, Hanoi University of Public Health, Hanoi Medical University, and Ho Chi Minh University of Medicine and Pharmacy collaborated with Seoul National University (Korea) and conducted a health system survey in the Quoc Oai district (of Hanoi capital) that represented northern rural Vietnam. Methods: The study design was a cross-sectional study. The survey covered different topics (more than 200 questions) and was administered in three separate questionnaires: 1) Basic information of all household members; 2) Household characteristics; and 3) Individual characteristics. Socio-demographic characteristics among the households and individuals were collected from 2,400 households sampled by multi-stage cluster sampling method: more than 200 questions. Results: The household size of Quoc Oai was larger than the national average and there was no significant difference in gender composition. In addition, the proportions of pre-elderly, age 55–64, and elderly group (65 years old and over) were higher than the national population statistics. In this context, demographic transition has begun in Quoc Oai. Conclusion: This study design description provides the basic information about a baseline survey of a future prospective cohort (as a part of a collaborative project on strengthening the health system in Vietnam) to the prospective data user of this survey.

부생가스 연료배관의 설계변경에 따른 안전성 평가

윤기봉(Kee Bong Yoon),응웬반장(Nguyen Van Giang),위엔두안선(Nguyen Tuan Son),정성용(Seong Yong Jeong),이주영(Joo Young Lee),김지윤(Ji Yoon Kim) 한국가스학회 2013 한국가스학회지 Vol.17 No.2

공정플랜트에는 다양한 배관이 고압, 고온의 인화성, 폭발성 물질을 이송하고 있다. 잦은 설계 변경 및 증설 등으로 복잡한 형상으로 배관이 형성되어 있는 경우가 많으나 배관의 구조가 단순하여 실제 위험성에 비해 안전 관리가 부족한 경우가 많다. 본 연구에서는 국내 한 업체에서 부생가스를 연료로 사용하던 배관을 설계 변경하여 천연가스와 혼합하여 사용하도록 사례를 활용하여, 배관의 안전성을 평가 하는 방법을 예시하였다. 배관의 설계 변경 후 안전성을 ASME 기준에 따라 재평가하고, 배관의 주요 관리부위를 결정하는 방법을 제시하였다. 배관의 분기 및 루프 등이 다수 복잡하게 연결되어있는 가스혼합용 믹싱드럼 배관 시스템을 대상으로 해석하였다. 배관의 주요부위 응력 민감도를 이해하기 위해 배관의 지지대 구속조건 및 외부 온도를 변화시켜 가면서 이들의 영향을 연구하였다. 또한 부생가스가 포함하고 있는 수소가스에 의한 손상 가능성에 대해서도 논의하였다. Various process piping usually carries out high flammable and explosible gas under high pressure and high temperature. Due to frequent change of design and structure it becomes more complicated and compactly located. The safety management level is relatively low since it is considered as simply designed component. In this study a safety assessment procedure is proposed for complicated piping system around a mixing drum in which natural gas and by-product gases were mixed. According to ASME code, pipe stress analysis was conducted for determining design margin at some key locations of the piping. These high stress locations can be used as major inspection points for managing the pipe integrity. Sensitivity analysis with outside temperature of the pipe and support constraint condition. Possible effect of hydroen gas to the pipe steel during the previous use of the by-product gas was also discussed.

Immunomodulation Effect of Crude Polysaccharide Extracted from Red Ginseng Processing by-Products

Tae Kil Eom,Jungman Kim,Nakwon Hwang,Son Nguyen Giang,Adeel Farooq,Mincheol Kim,Tatsya Unno,Ju Sung Kim 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10