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A Wirelessly Powered Expanding-Extending Robotic Capsule Endoscope for Human Intestine
Shu He,Guo-Zheng Yan,Quan Ke,Zhi-Wu Wang,Wen-Wen Chen 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.
Instruments for GI diagnostics are increasingly moving toward robotic capsule endoscopes because of their locomotion capabilities. This paper presents a wirelessly powered robotic capsule endoscope that can actively move in the small bowel exploiting the expanding–extending principle. After analyzing the demands of the locomotion, a novel radial motion mechanism with a large expanding/retracting radial ratio was designed, as was an axial motion mechanism with a compact structure. A control system with a special position detector to let the micro-motors avoiding stall state was developed to enhance the stability of the mechanism and reduce the robot’s power requirements. The wireless power system enabled the robot to inspect the full length of the intestinal tract. The assembled micro-robot was 14 mm in diameter and 45 mm in length. The maximum anchoring diameter was 32 mm, and the axial telescopic length was 9.5 mm. The test results proved the feasibility of the robot.
Comparison of Serum Tumor Associated Material (TAM) with Conventional Biomarkers in Cancer Patients
Shu, Jian,Li, Cheng-Guang,Liu, Yang-Chen,Yan, Xiao-Chun,Xu, Xu,Huang, Xin-En,Cao, Jie,Li, Ying,Lu, Yan-Yan,Wu, Xue-Yan,Liu, Jin,Xiang, Jin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Objective: To compare expression level of serum tumor associated materials (TAM) with several conventional serum tumor biomarkers, eg., carcinoembryonic antigen (CEA), carbohydrate antigen19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein(AFP), in selected solid tumors. Methods: Patients diagnosed histologically or cytologically with liver, breast, esophageal, gastric, colorectal or pancreatic cancers were enrolled into this study. After diagnosis, the level of TAM was determined by chemical colorimetry, and levels of conventional tumor markers was measured by chemiluminescence methods. Results: A total of 560 patients were enrolled into this study. No statistically significant difference was detected in TAM and the above mentioned tumor biomarkers in terms of their positivity and negativity ( P>0. 05). Conclusions: Detection of TAM in liver, breast, esophageal, gastric, colorectal, and pancreatic cancer patients demonstrates a good accordance with CEA, CA199, CA153, and AFP, thus suggesting that further study is warranted to verify whether TAM could be a surrogate for these conventional biomarkers.
Study on the preparation of nano-flaky anatase titania layer and their photovoltaic application
Shu-Yuan Wu,Wen-Chi Lo,Keh-Chang Chen,Ju-Liang He 한국물리학회 2010 Current Applied Physics Vol.10 No.2
Titania (TiO2), known to have wide energy band gap, can greatly absorb dye if specific surface area can significantly be increased and hence the photovoltaic efficiency. Dye-sensitized solar cells (DSSC) based on mesoporous titania has been drawn much attention over the past few years. An attempt in this study is to employ micro-arc oxidation (MAO) process and alkali treatment to develop titania layer with very high specific surface area on pure titanium surface. Specimens were applied an anodic dc voltage at 400–500 V in a phosphate electrolytic solution during MAO process, followed by the alkali treatment in 1.25 M NaOH solution to produce nano-flaky anatase TiO2 on surface, with nano-flakes about 50 nm in dimension thus largely increase specific surface area. Result of photovoltaic efficiency measurement of the assembled DSSC device show that ultimate efficiency (0.23%) can be obtained for the specimen postalkali treated in 1.25 M NaOH solution, which exhibits the highest surface area and thus the enhanced dye-absorbing efficiency.
Extensive Power Factor Calculation Method Using FPGA Considering Power Quality Disturbance
SHU-CHEN WANG,CHI-JUI WU 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
The power quality is more and more serious, because a lot of information technology equipments and power electric converters were used in recent years. Harmonic and load unbalance can affect the measurement result of power factor of utility. This paper used six formulas for power factor measurement, and they will be different according to the characteristics of load. The technology of semiconductor was more and more maturely. Design of SOC (System On a Chip) is a trend to achieve the strong and small volume in the future. The Fast Fourier Transform (FFT) is used to analyze the six formula of power factor. The simulation system was modeled in Hardware Description Language (VHDL) and some novel IP (intellectual property) cores, such as CORDIC core and FFT core by the way of Bottom-Up. The measurement data were employed to calculate active, reactive and apparent power. The average error rate of our design is about 0.05%.
Identification of Homer1 as a Potential Prognostic Marker for Intrahepatic Cholangiocarcinoma
Wu, San-Yun,Yu, Ming-Xia,Li, Xiao-Gai,Xu, Shu-Fang,Shen, Ji,Sun, Zhen,Zhou, Xin,Chen, Xing-Zhen,Tu, Jian-Cheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7
Background: The aim of the present study was to analyze whether Homer1 is a potential prognostic marker for intrahepatic cholangiocarcinoma (ICC). Materials and Methods: The expression of Homer1 in ICC tissue was detected with immunohistochemistry and levels of protein in ICC and paratumor tissues were evaluated by Western blotting. Survival analysis by the Kaplan-Meier method was performed to assess prognostic significance. Results: Homer1 expression was high in 67.4% (58/86) of ICC samples, and there was significant difference between ICC and adjacent noncancerous tissues (p<0.001); high expression was associated with poor histologic differentiation (p=0.019), TNM stage (p=0.014), lymph node metastasis (p=0.040), and lymphatic invasion (p=0.025). On Kaplan-Meier analysis, a comparison of survival curves of low versus high expressors of Homer1 revealed a highly significant difference in OS (p=0.001) and DFS (p=0.006), indicating that high expression of Homer1 was linked with a worse prognosis. Multivariate analyses showed that Homer1 expression was an independent risk factor predicting overall survival[Hazard ratio(HR), 7.52; 95% confidence interval (CI), 2.63-21.47; p=0.002] and disease-free survival (HR, 11.56; 95%CI, 5.17-25.96; p<0.001) in ICC. Conclusions: Homer1 promotes lymphatic invasion and associates with lymph node metastasis and poor prognosis of ICC. The current study shows that Homer1 may be an independent prognostic factor for ICC patients after curative resection, and it provides an important basis for screening/treating high-risk patients.