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BACKGROUND OF ENTHUSIASM FOR EDUCATION IN TANZANIA
Seungyoon Choi,Dong Ju Choi 한국외국어대학교 아프리카연구소 2019 Asian Journal of African Studies Vol.- No.45
This research aims to analyze the motivating factors on high levels of enthusiasm for education in Tanzania. Specifically, the study categorized motivating factors by social, economic, and cultural & historical contexts. For social factors, international influence and domestic atmosphere such as media and parent’s education level can be motivating factors for educational enthusiasm in Tanzania. In economic factors, economic benefits and parent’s income level were selected. Lastly, for cultural & historical factors, the nature of ethnic groups and the influence of colonization were chosen as motivating factors for people in Tanzania to have high educational enthusiasm. The study findings from the quantitative analysis indicate that three motivating factors have significant correlations with educational enthusiasm in Tanzania. At the same time, through regression analysis, all motivating factors have positive impact on the enthusiasm for education in Tanzania by representing the highest impact on social factors followed by economic, cultural and historical factors. From the in-depth interview, the research finds out that people in Tanzania have very high level of educational enthusiasm. Specifically, interviewees emphasized economic factors as a leading motivating factor for educational enthusiasm in Tanzania. Moreover, education specialists emphasized the importance of cultural & historical factors as a motivating factors for educational enthusiasm in Tanzania.
Gyeonggyu Choi,Seokwon Jang,Munseok Choi,Seungyoon Yang,Chunggeun Lee,Chang Moo Kang 한국간담췌외과학회 2022 Annals of hepato-biliary-pancreatic surgery Vol.26 No.1
Gallbladder cancer has a poor prognosis, especially in peritoneal carcinomatosis related to perforation of the gallbladder followed by bile spillage. Previously, curative-intent treatment was not considered in carcinomatosis from cancer of the biliary tract. A 72-year-old male was referred to the hospital with a perforated gallbladder cancer. Intraoperatively, the tumor was confined to the gallbladder and liver. We presented a case of intention-to-curative resection of perforated gallbladder cancer followed by intraoperative hyperthermic intraperitoneal chemotherapy.
혈액투석 유지 환자에서 혈청 인 수치와 동정맥루 기능부전의 상관관계
최유범 ( Yu Bum Choi ),김정현 ( Jung Hyun Kim ),이미정 ( Mi Jung Lee ),최승윤 ( Seungyoon Choi ),김형종 ( Hyung Jong Kim ) 대한내과학회 2020 대한내과학회지 Vol.95 No.1
목적: 혈액투석 환자에서 혈관접근로의 기능 유지는 혈액투석 치료 유지에 매우 중요하다. 따라서 동정맥루의 기능 부전을 일으킬 수 있는 위험인자를 파악하는 것이 중요하며, 이 연구의 목적은 혈청 인이 동정맥루의 혈류량에 미치는 관련성을 알아보고자 하였다. 방법: 본 연구는 2016년 11월부터 2017년 12월까지 차의 과대학교 분당차병원 인공신장실에서 주 3회 4시간 외래 혈 액투석 치료 중인 환자 총 62명의 환자를 대상으로 하였으며, 매달 시행하는 정기 혈액 검사를 통하여 혈청 인을 측정하였으며 시간에 따른 평균값을 계산하였다. 모든 환자는 왼쪽 팔의 동정맥루(단단 문합법)를 사용하여 혈액투석을 받았으며, 동정맥루 혈류량은 Transonic HD 03를 통해 측정하였다. 이때 측정된 600 mL/min보다 작은 값을 혈류량이 감소하였다고 정의하였다. 결과: 62명 중 14명에서 동정맥루 혈류량의 감소가 관찰되었고, 단변량 분석법에서 혈청 인 수치가 높을수록 초음파 희석법으로 측정한 동정맥루 혈류량의 감소와 관련성을 보였으며 나이, 성별, 혈액투석 시 혈류속도나 좌심실 수축기능, 혈청 칼슘 수치 등은 관련성이 없었다. 다변량 분석법에 서도 높은 혈청 인 수치는 자가혈관 동정맥루 혈류량의 감소와 독립적인 연관성의 결과를 보였고 다른 인자들은 통계적으로 유의한 연관이 없었다. 결론: 혈액투석 환자에서 높은 인 수치는 자가혈관 동정맥루 혈류량 감소에 영향을 미칠 수 있는 독립적 인자가 될수 있을 것으로 생각된다. 혈청 인 수치의 정기적인 감시가 동정맥루 기능 장애의 위험도를 예측하는 데 유용할 수 있으며, 적극적인 조절이 자가혈관 동정맥루의 기능을 유지하는데 도움이 될 수 있을 것으로 생각된다. Background/Aims: Maintaining vascular access (VA) is very important in the management of hemodialysis (HD) patients. Therefore, the identification of risk factors for decreased vascular access flow has clinical relevance. The aim of the present study was to investigate the impact of serum phosphorus (P) on autologous arteriovenous fistula flow in HD patients. Methods: Sixty-two maintenance HD patients who visited the dialysis unit of CHA Bundang Medical Center between November 2016 and December 2017 were included in the study. Serum P levels were obtained every month, and time-averaged serum P was calculated. All patients had left arm arteriovenous fistulas (AVF; side-to-side anastomosis). AVF flow was assessed by Transonic HD 03. Decreased AVF flow was defined as < 600 mL/min. Results: Decreased AVF flow was observed in 14 of 62 patients. In univariate analysis and multivariable analysis, higher serum P had a significant independent association with decreased AVF flow. Advanced age, reduced ejection fraction, low blood flow rate in dialysis, and higher serum calcium were not associated with AVF flow. Conclusions: The present study demonstrated that higher serum P was an independent risk factor for decreased autologous AVF flow in maintenance HD patients. Serial monitoring of serum P may be helpful in stratifying patients by risk of AVF dysfunction, and proper management of serum P levels may be helpful in maintaining flow through autologous AVFs. (Korean J Med 2020;95: 36-42)
Choi, Jae-Sun,Ryu, Jaewook,Bae, Woom-Yee,Park, Aron,Nam, Seungyoon,Kim, Ja-Eun,Jeong, Joo-Won MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.9
<P>Cancer cells undergo uncontrolled proliferation resulting from aberrant activity of various cell-cycle proteins. Therefore, despite recent advances in intensive chemotherapy, it is difficult to cure cancer completely. Recently, cell-cycle regulators became attractive targets in cancer therapy. Zingerone, a phenolic compound isolated from ginger, is a nontoxic and inexpensive compound with varied pharmacological activities. In this study, the therapeutic effect of zingerone as an anti-mitotic agent in human neuroblastoma cells was investigated. Following treatment of BE(2)-M17 cells with zingerone, we performed a 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay and colony-formation assay to evaluate cellular proliferation, in addition to immunofluorescence cytochemistry and flow cytometry to examine the mitotic cells. The association of gene expression with tumor stage and survival was analyzed. Furthermore, to examine the anti-cancer effect of zingerone, we applied a BALB/c mouse-tumor model using a BALB/c-derived adenocarcinoma cell line. In human neuroblastoma cells, zingerone inhibited cellular viability and survival. Moreover, the number of mitotic cells, particularly those in prometaphase, increased in zingerone-treated neuroblastoma cells. Regarding specific molecular mechanisms, zingerone decreased cyclin D1 expression and induced the cleavage of caspase-3 and poly (ADP-ribose) polymerase 1 (PARP-1). The decrease in cyclin D1 and increase in histone H3 phosphorylated (p)-Ser10 were confirmed by immunohistochemistry in tumor tissues administered with zingerone. These results suggest that zingerone induces mitotic arrest followed by inhibition of growth of neuroblastoma cells. Collectively, zingerone may be a potential therapeutic drug for human cancers, including neuroblastoma.</P>
Differential gene expression pattern in early gastric cancer by an integrative systematic approach
NAM, SEUNGYOON,LEE, JIEUN,GOH, SUNG-HO,HONG, SEUNG-HYUN,SONG, NAALEUM,JANG, SANG-GEUN,CHOI, IL JU,LEE, YEON-SU D.A. Spandidos 2012 International journal of oncology Vol.41 No.5
<P>To elucidate the molecular basis of early gastric cancer (EGC), the genome-wide expression pattern of cancer and normal tissues from 27 patients were analyzed by a microarray-based method. Using an integrative systematic bioinformatics approach, we classified the differentially expressed genes in EGC. Interestingly, the more highly expressed genes in EGC exhibited the most significant correlation with cell migration and metastasis. This implies that, even at the early stage of gastric cancer, the molecular properties usually observed in late-stage cancer are already present. Furthermore, we have found a novel association between the expression pattern and molecular pathways of EGC and estrogen receptor α (ERα)-negative breast cancer through cross-experimental analysis. These results provide new insights into the biological properties of EGC, as well as yielding useful basic data for the study of molecular mechanisms of EGC carcinogenesis.</P>
EFFECT OF ANISOTROPIC PLASTICITY ON THE PREDICTION OF FORMABILITY OF E-FORM MAGNESIUM ALLOY SHEET
Yongheon Lee,Seungyoon Jung,Hansung Baek,Jinwoo Lee,Moon-Seok Choi,이명규 한국자동차공학회 2019 International journal of automotive technology Vol.20 No.6
In this paper, the formability of E-FORM magnesium alloy sheet (as one of recent alloys for automotive magnesium sheets) is analyzed based on the comparison between the results of actual magnesium (Mg) roof forming and those of finite element (FE) simulations. The FE model considers anisotropic mechanical properties and forming limit diagram (FLD) of the investigated magnesium alloy sheet. Through the coupled experimental and numerical procedure, the dominating factors for improving the accuracy of the numerical simulations are further studied. A commercial finite element analysis program, AUTOFORM®, is used for the simulations, in which identified mechanical properties and forming limit criteria are implemented as functions of temperature and strain rate. The improvement in the prediction of formability during the warm forming of the E-FORM magnesium alloy sheet can be obtained by considering a modified hardening law at large strain region, sheet anisotropy, and the properly measured forming limit curve.
An online complete coverage approach for a team of robots in unknown environments
Hoang Huu Viet,SeungYoon Choi,TaeChoong Chung 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
This paper presents a novel approach to deal with the online complete coverage problem for a team of robots in unknown environments. In our approach each robot covers an unvisited region using a single boustrophedon motion until a robot reaches an ending point, which is surrounded by covered positions or obstacles. At the ending point the robot detects backtracking points based on the accumulated knowledge, plans the shortest backtracking path to the next starting point based on the proposed Theta<SUP>*</SUP> with multi-goals. Then, it follows the planed path to the next starting point to cover the next unvisited region. The robot team finishes the coverage task when no backtracking point is detected. Computer simulations show that our proposed approach is efficient for the complete coverage task of a robot team in terms of the coverage rate and the coverage path length.