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치질(痔疾)의 외치법(外治法)(비수술요법)과 세치법(洗痔法)에 관한 문헌적 고찰
이선용,서형식,Lee, Seon-Yong,Seo, Hyung-Sik 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.3
Objective : The object of this literatual study is to investigate the external therapy and irrigation-therapy(洗痔法) of hemorrhoids Methods : We have selected data related to the external therapy and irrigation-therapy(洗痔法) of hemorrhoids on the literature of Oriental medicine. And we analyzed the study. Results : 1. The external therapy of hemorrhoids is fundamental therapy. There are several external therapy, these are irrigation-therapy(洗痔法), fumigation-therapy(薰痔法), paint-therapt(塗痔法), and withering-therapy(枯痔法). 2. The effects of herbs used in this irrigation-therapy(洗痔法) are almost the same as ground rules of hemorrhoids therapy such as, remove heat to stop bleeding(淸熱止血), resolve damp-heat(淸化濕熱), tonify the blood and arrest bleeding(補血止血), clear away heat and loosen the bowels(淸熱通便), nourish blood to relieve dryness(養血潤燥), tonify thr spleen and replenish Ki(補中益氣) Conclusions : Through literatual Study, we basically understood the external therapy and irrigation-therapy(洗痔法) of hemorrhoids. In the study of irrigation-therapy(洗痔法), it seems that further clinical studies on hemorrhoids therapy.
이선용,서형식,Lee, Seon-Yong,Seo, Hyeong-Sik 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.2
Objectives : This experimental study was performed to investigate the effects of Sulfur extract on anti-inflammation and anti-Propionibacterium acnes. Methods : The cytotoxicity of Sulfur extract about viability of Raw 264.7 cell were tested using a colorimetric tetrazolium assay(MTT assay). To investigate the anti-inflammation effects of Sulfur extract on LPS-induced macrophage Raw 264.7 cell, we used ELISA kit and Western blots. We evaluated anti-oxidation effects of Sulfur extract on HaCaT cell by Enzyme recycling method. And we investigated the inhibitory effects of Sulfur extract on Propionibactrium acnes using paper disk diffusion method. Results: 1. Sulfur extract has a little cytotoxicity in Raw 264.7 cell. 2. Concentration of $100\;{\mu}g/m{\ell}$ Sulfur extract inhibited the production of NO in the Raw 264.7 cell stimulated with LPS. 3. Sulfur extract showed a oxidation inhibition effect by decreasing the DPPH radicals. 4. Sulfur extract has not the significant inhibition effect of Propionibactrium acnes. Conclusions: These results indicate that Sulfur extract has anti-inflammation and anti-oxidation effects. If further study is performed, the use of Sulfur extract will be valuable and benificial in the therapy of Propionibactrium acnes.
이선용,정재호,서형식,Lee, Seon-Yong,Jung, Jae-Ho,Seo, Hyung-Sik 대한한방안이비인후피부과학회 2009 한방안이비인후피부과학회지 Vol.22 No.3
Objectives : The object of this literature study is to investigate the external treatment of seborrheic dermatitis. Methods : We have selected data related to the external treatment of seborrheic dermatitis on the literature of Oriental medicine. And we analyzed the study. Results : 1. The external treatment of seborrheic dermatitis is fundamental treatment. There are several external treatment, these are paint-treatment, shampoo-treatment and pillow-treatment. 2. Prescription used in external treatment of seborrheic dermatitis is Yungi-go(潤肌膏), Okgi-san(玉肌散), Yongnoe-go(龍腦膏), Johyub-tang(?莢湯). 3. Herb used in external treatment of seborrheic dermatitis is Angelicae dahuricae Radix(白芷), Lysimachia foenumgraecum Hance(零陵香), Veratri Nigri Rhizoma Et Radix(藜蘆), Cannabis Fructus(大麻). Conclusions : Through literatual Study, we basically understood the external treatment of seborrheic dermatitis. In the study of external treatment, it seems that further clinical studies on seborrheic dermatitis treatment.
합성된 탄산염 및 황산염 그린 러스트의 형성 메커니즘과 이화학적 특성 규명
이선용,최수연,장봉수,이영재,Lee, Seon Yong,Choi, Su-Yeon,Chang, Bongsu,Lee, Young Jae 한국암석학회한국광물학회 2022 광물과 암석 (J.Miner.Soc.Korea) Vol.35 No.2
Carbonate green rust (CGR) and sulfate green rust (SGR) commonly occur in nature. In this study, CGR and SGR were synthesized through co-precipitation, and their formation mechanisms and physicochemical properties were investigated. X-ray diffraction (XRD) and Rietveld refinement showed both CGR and SGR with layered double hydroxide structure were successfully synthesized without any secondary phases under each synthetic condition. Refined structural parameters (unit cell) for two green rusts were a (=b) = 3.17 Å and c = 22.52 Å for CGR and a (=b) = 5.50 Å and c = 10.97 Å for SGR with the crystallite size 57.8 nm in diameter from (003) reflection and 40.1 nm from (001) reflections, respectively. Scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS) results showed that both CGR and SGR had typical hexagonal plate-like crystal morphologies but their chemical composition is different in the content of C and S. In addition, Fourier transform infrared (FT-IR) spectroscopy analysis revealed that carbonate (CO<sub>3</sub><sup>2-</sup>) and sulfate (SO<sub>4</sub><sup>2-</sup>) molecules were occupied as interlayer anions of CGR and SGR, respectively. These SEM/EDS and FT-IR results were in good agreement with XRD results. Changes in the solution chemistry (i.e., pH, Eh and residual iron concentrations (Fe(II):Fe(III)) of the mixed solution) were observed as a function of the injection time of hydroxyl ion (OH<sup>-</sup>) into the iron solution. Three different stages were observed in the formation of both CGR and SGR; precursor, intermediator, and green rust in the formation of both CGR and SGR. This study provides co-precipitation methods for CGR and SGR in a way of the stable synthesis. In addition, our findings for the formation mechanisms of the two green rusts and their physicochemical properties will provide crucial information with researches and industrials in utilizing green rust.
X-선 흡수 분광법(XAS)을 이용한 이중층수산화물-나노복합체(LDH-NCs)의 형성 및 음이온성 오염물질 저감 특성 규명
이선용(Seon Yong Lee),이영재(Young Jae Lee) 대한지질학회 2021 대한지질학회 학술대회 Vol.2021 No.10
비소(As)와 인(P)은 인위적/자연적 요인을 통해 수계에 다양하게 유입되어 수생태계와 인간의 건강을 위협하는 대표적인 음이온성 오염물질이다. 이중층수산화물(layered double hydroxide, LDH)은 점토의 일종으로 두 팔면체 층간에 존재하는 음이온의 강한 교환작용을 통해 음이온 계열 오염물질들을 효과적으로 저감할 수 있으나, 나노 LDH 결정의 자가 응집으로 그 효과가 감소되는 단점이 있다. 이러한 문제는 기반 물질 표면에 고반응성 물질을 정밀하게 결합한 나노복합체(nanocomposites, NCs)를 통해 해결 가능하다. 본 연구에서는 LDH와 기반 (광)물질이 지닌 특성을 과학적으로 응용하여 쉽고, 효율적인 방법(예, 용해-재침전, 열수합성, 소성)을 통해 독창적인 이중층수산화물-(광물)나노복합체(LDH-NCs)를 합성하였다. 또한, 다양한 흡착배치실험과 방사광가속기의 X-선 흡수 분광법(XAS)을 포함한 액체 및 고체상 분석들을 복합적으로 활용하여 인, 비소와 다양한 LDH-NCs 사이에서 발생하는 반응 메커니즘들을 원자·분자 규모에서 상세히 규명하여 효과적인 저감 조건을 제시하였다. 특히, XAS는 X-선 회절(XRD) 및 투과전자현미경(TEM) 분석과 함께 합성된 시료의 구조 파라미터 및 원자 배치와 같은 복잡한 미구조적 특성을 밝히는데 유용하게 이용되었다. 뿐만 아니라, 흡착된 오염물질의 표면 결합 특성(예, outer-sphere complex vs. inner-sphere complex 결합 등)을 밝혀 반응 메커니즘을 보다 명확히 제시하는 데 큰 역할을 하였다. 본 연구는 다양한 나노광물질의 형성 및 구조, 그리고 이화학적 특성에 대한 이해뿐만 아니라, 이들과 다양한 음이온성 오염물질들과의 미시적 규모의 상호작용에 대한 메커니즘적 이해와 이를 통한 환경 문제 해결에 있어 효과적이며 과학적인 접근법을 제시하였다. 향후 지질환경과학 분야에서 방사광가속기의 적극적인 활용은 자연 광물질의 형성과 표면 및 구조에서 기인하는 다양한 이화학적 반응에 대한 더욱 정밀하고 정확한 이해와 예측에 크게 기여할 것으로 기대된다.
Effects of Temperature on The Crystallization and Structural Stability of Struvite (MgNH₄PO₄·6H₂O)
Seon Yong Lee(이선용),Bongsu Chang(장봉수),Sue A Kng(강수아),Young Jae Lee(이영재) 한국암석학회 2020 암석학회지 Vol.33 No.1
다양한 온도에서 스트루바이트(struvite, MgNH₄PO₄·6H₂O)들이 합성 및 건조되었다. 스트루바이트의 결정화와 그 구조적 특성은 합성 온도와 건조 온도 모두에게 큰 영향을 받았다. 스트루바이트는 합성 온도 ≤30℃에서 순조롭게 형성되었으며, 결정도는 합성 온도와 역의 관계를 보였다. 또한, 스트루바이트 결정도는 건조 온도가 45℃에서 60℃로 증가함에 따라 감소되었으며, 이는 열분해로 인해 발생한 구조적 물 분자와 암모늄 이온의 손실로 촉진되었다. 그러나 낮은 합성 온도에서 합성된 스트루바이트 일수록 높은 결정도를 가지며, 열분해에 의한 비정질화가 억제되었다. 본 결과는 저온의 열역학적으로 안정한 조건에서 형성된 스트루바이트는 높은 결정성을 보이며, 이에 따른 구조 안정성과 열저항성을 갖음을 입증한다. A series of struvite (MgNH₄PO₄·6H₂O) was synthesized and dried at various temperatures (15-60℃). Crystallization of struvite and its structural properties were significantly influenced by synthetic and drying temperature. Struvite was favorably formed at synthetic temperatures ≤30℃ with an inverse relationship between the crystallinity and synthetic temperature. The crystallinity of struvite was also significantly reduced by an increase in drying temperature from 45℃ to 60℃ due to the loss of structural water molecules and ammonium ions by the facilitated thermal decomposition. However, struvite formed at lower synthetic temperature showed higher crystallinity, and its amorphization by thermal decomposition was inhibited. These results demonstrate that struvite formed at low temperature with an stable condition thermodynamically through favorable crystallization shows high crystallinity and stability with respect to the structural and thermal resistance.