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Jang, Yunchang,Roh, Hyun-Joon,Park, Seolhye,Jeong, Sangmin,Ryu, Sanywon,Kwon, Ji-Won,Kim, Nam-Kyun,Kim, Gon-Ho Elsevier 2019 CURRENT APPLIED PHYSICS Vol.19 No.10
<P><B>Abstract</B></P> <P>A phenomenology-based virtual metrology (VM) for monitoring SiO<SUB>2</SUB> etching depth was proposed by Park (2015). It achieved high prediction accuracy by introducing newly developed plasma information (PI) variables as designated inputs, called PI-VM. The PI variables represent the state of the plasma, the sheath, and the target during the process. We investigate how a PI variable can help to improve prediction accuracy of VM and how it plays a special role in the statistical selection. We choose only PI<SUB>EEDF</SUB> among the three PI variables to focus on the investigation. The PI<SUB>EEDF</SUB> is determined from the ratio of line-intensities of optical emission spectroscopy. We apply Pearson's correlation filter (PCF), principal component analysis (PCA), and stepwise variable selection (SVS) as statistical selection methods on the variables set including PI<SUB>EEDF</SUB> or not. Multilinear regression is used to model the VM. This study reveals that PI<SUB>EEDF</SUB> variable is a good variable in terms of independence from other input variables and explanatory power for an output variable. Especially, VM using SVS method applied to variable sets including PI<SUB>EEDF</SUB> achieves the highest accuracy, comparable to Park's PI-VM. This study shows that PI<SUB>EEDF</SUB> variable is particularly useful for monitoring of the fine variations in semiconductor manufacturing process and it also extends the utilization of OES sensor data.</P>
Park, Sangmin,Shin, Hyeji,Park, Yeeun,Choi, Ilgyu,Park, Byoungduck,Lee, Ki Yong Elsevier 2018 Bioorganic chemistry Vol.80 No.-
<P><B>Abstract</B></P> <P>An effective screening method for inhibitors of NO production in natural products using LC-QTOF MS/MS coupled with a cell-based assay was proposed. The ethyl acetate fraction of <I>Catalpa ovata</I> exhibited a strong inhibitory effect on NO production in lipopolysaccharide-induced BV2 microglia cells. We attempted to identify the active constituents of <I>C. ovata</I> by using LC-QTOF MS/MS coupled with a cell-based assay. Peaks at approximately 14–15 min on the MS chromatogram were estimated to be the bioactive constituents. A new iridoid compound, 6-<I>O-trans</I>-feruloyl-3β-hydroxy-7-deoxyrehamaglutin A (<B>4</B>), and nine known compounds (<B>1</B>–<B>3, 5</B>–<B>10</B>) were isolated from the ethyl acetate fraction of <I>C. ovata</I> by repeated column chromatography. Compounds <B>3</B>, <B>4</B>, <B>5</B>, <B>7</B>, and <B>8</B> significantly attenuated lipopolysaccharide-stimulated NO production in BV2 cells. Our results indicate that LC-QTOF MS/MS coupled with a cell-based NO production inhibitory assay successfully predicted active compounds without a time-consuming isolation process.</P> <P><B>Highlights</B></P> <P> <UL> <LI> LC-QTOF MS/MS coupled with a cell-based NO production inhibitory assay was developed. </LI> <LI> EtOAc fraction of <I>Catalpa ovata</I> showed inhibitory effect on NO production. </LI> <LI> Compounds between 14 and 15 min on Mass chromatogram inhibited NO production. </LI> <LI> Anti-inflammatory activity was tested on isolated compounds including a new compound. </LI> <LI> Predicted active compounds from developed method matched with the experimental data. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
박상민(Park Sangmin) 한국수사학회 2011 수사학 Vol.0 No.15
This thesis deals with the types and the meanings of death in Park, Kyongni's novel, Toji(土地). Based on moral responsibility of death, the types of death in Toji can be categorized in natural death, death of disease, suicide, and homicide. The meanings and rhetoric characteristics of death on each category can be analyzed and derive the following conclusions: Firstly, unnatural death cases such as death of disease, suicide, and homicide are a lot more common than natural death cases on Toji. This feature primarily comes from the structural characteristics of Toji which progresses from stable social conditions to unstable social conditions. However, more fundamental rationale arises from Toji's rhetoric strategy to issue the moral discourse through various cases of death. Even though there is no explicit description on the meaning of death, the narrator raise the issue of moral responsibility and expand its unique moral discourse through many examples of death and individual cases. Secondly, the narrator has romantic attitude on suicide rather than making any moral criticism. Suicide is the last choice for the characters who want to solve their problems as the situation becomes critical. The narrator tends to describe those behaviors as the sanctity. Lastly, death becomes an ordinary routine by the endless cases of death. The readers encounter death, which is the utmost pain, in the middle of their life. Paradoxically, the readers obtain the strength to overcome the fear of death through these experiences. By clearly specifying the omnipresence of death, Toji makes the death an ordinary event and ultimately provides a hideout to overcome the fear of death.
Hardware-Accelerated Multipipe Parallel Rendering of Large Data Streams
Park, Sanghun,Park, Sangmin,Bajaj, Chandrajit,Ihm, Insung Korea Computer Graphics Society 2001 컴퓨터그래픽스학회논문지 Vol.7 No.2
최근 과학적 데이터의 증가 결과로, 매우 방대한 크기의 볼륨 데이터들이 점차로 일반화되고 있다. 다양한 텍스춰 기반 볼륨 렌더링 알고리듬들이 제안되었으나, 대부분의 방법들이 하드웨어가 갖고 있는 텍스춰 메모리보다 작은 크기의 볼륨 데이터를 가시화하는데 촛점을 맞추고 있다. 본 논문은 멀티파이프 시스템 구조상에서 매우 큰 정적 데이터와 시간 가변 데이터를 위한 새로운 병렬 볼륨 렌더링 스킴에 대해 설명한다. 이 스킴은 큰 볼륨을 동적으로 작은 크기의 블릭으로 분할하고, 이를 그래픽스 파이프에 적절히 할당함으로써 텍스춰 교체 비용을 최소화 한다. 이 기법은, 수행중에 법선 벡터를 계산하고 OpenGL 컬러 행렬을 이용하여 퐁 쉐이딩 영상을 쉽게 생성할 수 있다. 우리는 SGI Onyx2 시스템을 이용하여 큰 크기의 다양한 데이터에 대해 실험한 결과를 보인다. As a result of the recent explosive growth of scientific data, extremely large volume datasets have become increasingly commonplace. While several texture-based volume rendering algorithms have been proposed, most of them focused on volumes smaller than the hardware's available texture memory. This paper presents a new parallel volume rendering scheme for very large static and time-varying data on a multipipe system architecture. Our scheme subdivides large volumes dynamically into smaller bricks, and assigns them adaptively to graphics pipes to minimize the costs of texture swapping. With the new method, Phong shaded images can be easily created by computing the gradients on the fly and using the color matrix feature of OpenGL. We report experimental results on an SGI Onyx2 for the various large datasets.
Investigation of the Long-Term Effects of Amantadine Use in Parkinson’s Disease
Sangmin Park,Beomseok Jeon 대한파킨슨병및이상운동질환학회 2023 Journal Of Movement Disorders Vol.16 No.2
Amantadine has been used for the symptomatic treatment of Parkinson’s disease (PD) as monotherapy, adjuvant therapy, or as an anti-dyskinetic agent. However, amantadine has been known to be ineffective in the later months, and the effects on motor fluctuation or nonmotor symptoms are unclear