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      • KCI등재

        Analysis of Male and Female Nurses’ Attitudes toward Nurse Uniforms in South Korea: The Functional, Expressive, and Aesthetic (FEA) Framework

        Seon Mi Jang,Sae Eun Lee,Jeong-Ju Yoo 한국복식학회 2021 International journal of costume and fashion Vol.21 No.1

        The goals are to investigate attitudes toward pantsuit uniforms versus scrubs between male and female nurses, and to analyze nurse uniform design preferences. It is important to thoroughly investigate both male and female nurses’ attitudes toward uniform designs. Applying the Functional, Expressive, and Aesthetic conceptual framework serves to understand nurses’ attitudes toward uniforms. Five female and six male nurses in South Korea participated in focus group interviews for this study. The participants revealed that male and female nurses hold similar views regarding their functional aspects with respect to comfort, convenience, and infection risk. Concerning the expressive aspects of uniforms, both male and female nurses believe that scrubs enhance their occupational value, status expression, self-control, self-image, and professional image, compared to pantsuits. With respect to aesthetic aspects, however, the male and female nurses in this study report different views of androgyny. While scrubs share both feminine and masculine stylistic traits, the male nurses still view their current uniforms as feminine in design. The FEA framework enhances an understanding of male and female nurses’ attitudes toward uniforms by investigating their perspectives. The study implications provide further support for design improvement and research in the field of clothing within the health professions.

      • KCI등재

        Association Between Clinical Burden and Blood Eosinophil Counts in Asthma: Findings From a Korean Adult Asthma Cohort

        Kim Mi-Yeong,조은정,Kim Sujeong,Kim Min-Hye,Jung Jae-Woo,Kim Joo-Hee,Moon Ji-Yong,Kwon Jae-Woo,Lee Jae-Hyun,Park Chan Sun,Jin Hyun Jung,Shin Yoo Seob,Kim Sae-Hoon,Cho Young-Joo,Park Jung-Won,Cho Sang-Heo 대한의학회 2022 Journal of Korean medical science Vol.37 No.7

        Background: Some reports have suggested that the clinical and economic burdens of asthma are associated with blood eosinophil levels. The association between clinical burden and blood eosinophil counts were evaluated in a Korean adult asthma cohort. Methods: Clinical information including blood eosinophil counts that were not affected by systemic corticosteroids were extracted from the Cohort for Reality and Evolution of Adult Asthma in Korea database. Clinical burden was defined as 1) asthma control status, 2) medication demand and 3) acute exacerbation (AE) events during 1 consecutive year after enrollment. All patients were divided into atopic and non-atopic asthmatics. The associations between asthma outcomes and the blood eosinophil count were evaluated. Results: In total, 302 patients (124 atopic and 178 non-atopic asthmatics) were enrolled. In all asthmatics, the risk of severe AE was higher in patients with blood eosinophil levels < 100 cells/µL than in patients with levels ≥ 100 cells/µL (odds ratio [OR], 5.406; 95% confidence interval [CI], 1.266–23.078; adjusted P = 0.023). Among atopic asthmatics, the risk of moderate AE was higher in patients with blood eosinophil levels ≥ 300 cells/µL than in patients with levels < 300 cells/µL (OR, 3.558; 95% CI, 1.083–11.686; adjusted P = 0.036). Among non-atopic asthmatics, the risk of medication of Global Initiative for Asthma (GINA) steps 4 or 5 was higher in patients with high blood eosinophil levels than in patients with low blood eosinophil levels at cutoffs of 100, 200, 300, 400, and 500 cells/µL. Conclusion: The baseline blood eosinophil count may predict the future clinical burden of asthma.

      • KCI등재

        Oral Single Dose Toxicity Study of Low Molecular Fucoidan in Mice

        Young-Mi Jung,Kang Min Yoo,Dong-Chan Park,Tae-Kwon Kim,Hyeung-Sik Lee,Sae-Kwang Ku 한국독성학회 2008 Toxicological Research Vol.24 No.1

        This study was conducted to obtain information of the oral dose toxicity of low molecular fucoidan (LMF) in male and female mice. In order to calculate 50% lethal dose (LD50) and approximate lethal dose (LD), test material was once orally administered to male and female ICR mice at dose levels of 2000, 1000, 500, 250, 125 and 0 (vehicle control) ㎎/㎏ (body wt.). The mortality and the changes on body weight, clinical signs, gross observation and organ weight and histopathology of principle organs were monitored 14 days after LMF treatment. We could not find any mortalities, clinical signs, body weight changes and gross findings. In addition, significant changes in the organ weight and histopathology of principal organs were not observed except for some sporadic findings. The results obtained in this study suggest that LMF may not be toxic in mice and may be therefore safe for clinical use. The LD50 and approximate LD in mice after single oral dose of LMF were considered over 2000 ㎎/㎏ in both female and male mice.

      • Effects of a three‐month combined exercise programme on fibroblast growth factor 21 and fetuin‐A levels and arterial stiffness in obese women

        Yang, Sae Jeong,Hong, Ho Cheol,Choi, Hae Yoon,Yoo, Hye Jin,Cho, Geum Ju,Hwang, Teak Geun,Baik, Sei Hyun,Choi, Dong Seop,Kim, Seon Mi,Choi, Kyung Mook Blackwell Publishing Ltd 2011 Clinical endocrinology Vol.75 No.4

        <P><B>Summary</B></P><P><B>Objective </B> We examined the relationship between brachial‐ankle pulse wave velocity (baPWV) reflecting arterial stiffness and the levels of novel hepatokines fibroblast growth factor 21 (FGF21) and fetuin‐A. In addition, we evaluated the effect of a 3‐month combined aerobic and resistance exercise programme on FGF21 and fetuin‐A levels as well as arterial stiffness in obese women.</P><P><B>Methods </B> Forty nondiabetic, obese women (body mass index = 27·6 ± 2·4 kg/m<SUP>2</SUP>) were included in the study and were compared before and after a 3‐month exercise programme, which was composed of 45 min of aerobic exercise at an intensity of 60–75% of the age‐predicted maximum heart rate (300 kcal/session) and 20 min of resistance training (100 kcal/session) five times a week. All exercise sessions were supervised by a professional exercise physiologist.</P><P><B>Results </B> At baseline, baPWV levels were correlated with age, body mass index (BMI), systolic blood pressure (SBP), high density lipoprotein cholesterol, fasting glucose and serum FGF21 levels. In a multiple stepwise regression analysis using baPWV as a dependent variable, baPWV levels were associated with age, BMI, SBP, FGF21 and fetuin‐A levels (<I>R</I><SUP>2</SUP> = 0·744). After the exercise programme, BMI, waist circumference, SBP, diastolic blood pressure and triglyceride levels were significantly decreased. Moreover, baPWV values were significantly improved (<I>P </I><<I> </I>0·001) along with modest decrease in FGF21 levels (<I>P </I>=<I> </I>0·043). However, fetuin‐A levels were not changed significantly (<I>P </I>=<I> </I>0·202).</P><P><B>Conclusions </B> A 3‐month combined exercise programme decreases the FGF21 levels as well as arterial stiffness in obese Korean women.</P>

      • 분산 파일시스템을 위한 효율적인 협력캐쉬 알고리즘

        박새미(Park Sae-Mi),이석재(Lee Seok-Jae),유재수(Yoo Jae-Soo) 한국콘텐츠학회 2003 한국콘텐츠학회 종합학술대회 논문집 Vol.1 No.2

        분산 파일시스템 환경에서는 디스크 접근 비용을 줄이기 위해 각 노드에 캐쉬된 데이터를 서로 공유하는 협력캐쉬 기법이 사용된다. 협력캐쉬 기법은 분산되어있는 시스템들의 캐쉬정보를 서로 공유하여 가상으로 더 큰 캐쉬를 형성함으로써 캐쉬 히트율을 높이고 디스크 접근을 줄이는 방법이다. 기존에 제안된 협력캐쉬 기법들은 캐쉬에 대한 근사정보를 이용하여 메시지 비용을 줄이고, 로컬캐쉬영역과 글로벌 캐쉬영역을 가변적으로 사용하여 캐쉬히트율을 높이고 있다. 또한 캐시교체시 교체된 블록을 비활동적인 노드로 보내어 계속 캐쉬에 유지하도록 하여 글로벌 캐시히트율을 높이는 장점을 갖는다. 그러나 잘못된 근사정보가 성능을 저하시킬 수 있으며 일관성 유지를 위한 메시지교환 비용이 많이 든다는 단점을 갖고 있다. 또한 비활동적인 노드를 선정하기 위해 사용되는 각 노드의 에이지정보 관리비용이 많이 드는 단점을 갖고 있다. 본 논문에서는 정확한 캐쉬정보를 유지하며 일관성 유지비용과 캐시에이지정보 관리비용을 최소화시키는 협력캐쉬 알고리즘을 제안한다. 그리고 성능평가를 통해 기존의 협력캐쉬 기법과 비교하여 제안하는 알고리즘의 우수성을 보인다. In distributed file-systems, cooperative caching algorithm which owns the data cached at each node jointly is used to reduce an expense of disk access. Cooperative caching algorithm is the method that increases a cache hit-ratio and decrease a disk access as it holds the cache information of distributed systems in common and makes cache larger virtually. Recently, several cooperative caching algorithms decrease the message costs by using approximate information of the cache and increase the cache hit-ratio by using local and global cache fields dynamically. And they have an advantage that increases the whole field hit-ratio by sending a replaced block to the idel node on cache replacement in order to maintain the replaced block in the cache field. However the wrong approximate information deteriorates the performance, the concistency maintenance goes to great expense to exchange messages and the cost that manages Age-information of each node to choose the idle node increases. In this thesis, we propose a cooperative cache algorithm that maintains correct cache information, minimizes the maintains cost for consistency and the management cost for cache Age-information. Also, we show the superiority of our algorithm through the performance evaluation.

      • SCOPUSKCI등재

        Oral Single Dose Toxicity Study of Low Molecular Fucoidan in Mice

        Jung, Young-Mi,Yoo, Kang-Min,Park, Dong-Chan,Kim, Tae-Kwon,Lee, Hyeung-Sik,Ku, Sae-Kwang Korean Society of ToxicologyKorea Environmental Mu 2008 Toxicological Research Vol. No.

        This study was conducted to obtain information of the oral dose toxicity of low molecular fucoidan (LMF) in male and female mice. In order to calculate 50% lethal dose ($LD_{50}$) and approximate lethal dose (LD), test material was once orally administered to male and female ICR mice at dose levels of 2000, 1000, 500, 250, 125 and 0 (vehicle control) mg/kg (body wt.). The mortality and the changes on body weight, clinical signs, gross observation and organ weight and histopathology of principle organs were monitored 14 days after LMF treatment. We could not find any mortalities, clinical signs, body weight changes and gross findings. In addition, significant changes in the organ weight and histopathology of principal organs were not observed except for some sporadic findings. The results obtained in this study suggest that LMF may not be toxic in mice and may be therefore safe for clinical use. The $LD_{50}$ and approximate LD in mice after single oral dose of LMF were considered over 2000 mg/kg in both female and male mice.

      • SCOPUSKCI등재

        The Effectiveness of Real-Time PCR Assay, Compared with Microbiologic Results for the Diagnosis of Pulmonary Tuberculosis

        ( Seo Woo Kim ),( Sae In Kim ),( Seok Jeong Lee ),( Jin Hwa Lee ),( Yun Ju Ryu ),( Sung Shine Shim ),( Yoo Kyoung Kim ),( Mi Ae Lee ),( Jung Hyun Chang ) 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.1

        Background: The incidence of tuberculosis (TB) in Korea is relatively high compared to the other Organisation for Economic Co-operation and Development (OECD) countries, with a prevalence of 71 per 100,000 in 2012, although the incidence is declining. Real-time polymerase chain reaction (PCR) has been introduced for the rapid diagnosis of TB. Recently, its advantage lies in higher sensitivity and specificity for the diagnosis of TB. This study evaluated the clinical accuracy of real-time PCR using respiratory specimens in a clinical setting. Methods: Real-time PCR assays using sputum specimens and/or bronchoscopic aspirates from 2,877 subjects were reviewed retrospectively; 2,859 subjects were enrolled. The diagnosis of TB was determined by positive microbiology, pathological findings of TB in the lung and pleura, or clinical suspicion of active TB following anti-TB medication for more than 6 months with a favorable response. Results: Sensitivity, specificity, and accuracy were 44%, 99%, and 86% from sputum, and 65%, 97%, and 87% from bronchoscopic aspirates, respectively. For overall respiratory specimens, sensitivity was 59%, specificity was 98%, and accuracy increased to 89%. Conclusion: Positivity in real-time PCR using any respiratory specimens suggests the possibility of active TB in clinically suspected cases, guiding to start anti-TB medication. Real-time PCR from selective bronchoscopic aspirates enhances the diagnostic yield much more when added to sputum examination.

      • KCI등재

        2021 Korean Thyroid Imaging Reporting and Data System and Imaging-Based Management of Thyroid Nodules: Korean Society of Thyroid Radiology Consensus Statement and Recommendations

        Ha Eun Ju,Chung Sae Rom,Na Dong Gyu,Ahn Hye Shin,Chung Jin,Lee Ji Ye,Park Jeong Seon,Yoo Roh-Eul,Baek Jung Hwan,Baek Sun Mi,조성휘,Choi Yoon Jung,Hahn Soo Yeon,Jung So Lyung,Kim Ji-hoon,Kim Seul Kee,Kim 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.12

        Incidental thyroid nodules are commonly detected on ultrasonography (US). This has contributed to the rapidly rising incidence of low-risk papillary thyroid carcinoma over the last 20 years. The appropriate diagnosis and management of these patients is based on the risk factors related to the patients as well as the thyroid nodules. The Korean Society of Thyroid Radiology (KSThR) published consensus recommendations for US-based management of thyroid nodules in 2011 and revised them in 2016. These guidelines have been used as the standard guidelines in Korea. However, recent advances in the diagnosis and management of thyroid nodules have necessitated the revision of the original recommendations. The task force of the KSThR has revised the Korean Thyroid Imaging Reporting and Data System and recommendations for US lexicon, biopsy criteria, US criteria of extrathyroidal extension, optimal thyroid computed tomography protocol, and US follow-up of thyroid nodules before and after biopsy. The biopsy criteria were revised to reduce unnecessary biopsies for benign nodules while maintaining an appropriate sensitivity for the detection of malignant tumors in small (1–2 cm) thyroid nodules. The goal of these recommendations is to provide the optimal scientific evidence and expert opinion consensus regarding US-based diagnosis and management of thyroid nodules.

      • Effect of Various Percoll Washings on Capacitation Status and Sperm Survival in Frozen-thawed Bovine Epididymal Spermatozoa

        Sung-Jae Yoon,Yoo-Jin Park,Woo-Sung Kwon,Kyu-Hyun Jeong,Sae-Mi Yoo,El-Sayed A. Mohamed,Myung-Geol Pang 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

        The objective of this study was to examine the effect of various discontinuous Percoll washing conditions on sperm capacitation status and sperm survival. Frozen epididymal sperm samples from 3 bulls (0.5 ml plastic straws, 6% glycerol in egg yolk- Tris-glycerol extender) were thawed in 37℃ water bath for 1 min. To rule out individual variation, 3 sperm samples were mixed after thawing. The mixed samples then were randomly allocated to 12 treatment groups. Briefly, the spermatozoa were centrifuged for three different time lengths (10, 20, and 30 min) at two gravities (300 X g and 700 X g) through two concentrations of discontinuous Percoll density gradient of 1 ml 90%: 1 ml 45% Percoll and 2 ml 90%: 2 ml 45% Percoll to remove extender, debris, and dead spermatozoa. Sperm capacitation status and sperm survival were evaluated using combined Hoechst 33258 and chlortertracycline fluorescence staining assay. The acrosome reacted spermatozoa (AR pattern), uncapaciated spermatozoa (F pattern) and sperm survival were significantly correlated with centrifugation time (p< 0.01). Significantly decreased F pattern observed as centrifugal time increased. As centrifugal time increased, spermatozoa with F pattern decreased and spermatozoa showing AR pattern increased. Moreover, the dead spermatozoa were significantly stimulated in time-dependent manner. However, there were no significant differences in various force of centrifugation and Percoll volume. These results suggest that only centrifugation time significantly affects sperm capacitation status and sperm survival.

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