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Nguyen Huu-Manh,Duong The-Khang,Nguyen Van-Khuyen,Nguyen Thi-Khanh-Ly,Dong Thi-Hoang-Yen,Nguyen Canh-Hung,Tung Nguyen-Thach 한국약제학회 2024 Journal of Pharmaceutical Investigation Vol.54 No.2
Purpose A two-step experimental design was used to develop a lornoxicam (LOR)-loaded topical hydrogel patch. We specifically focused on the simultaneous effect of the ion pair formation agent (triethanolamine [TEA]) and the chemical enhancer (cremophor RH40 [RH40]) on flux and conducted physicochemical studies and skin physiology assessments to obtain further information. Methods Drug-in-adhesive patches were fabricated using a micrometer-adjustable film applicator. The applied Design of Experiments (DoE) approach consisted of the Fractional Factorial Resolution V + design and the Central Composite Face design established by the MODDE® 12.0 software. Molecular-level drug-excipient interactions were investigated using infrared (IR) and proton nuclear magnetic resonance (1H NMR) spectroscopy. The effects on skin physiological function was assessed using DermaLab Combo. Results DoE results revealed that TEA enhanced flux by 3.14-fold, whereas RH40 reduced it by 4.62-fold. The addition of RH40 resulted in the disappearance of the proton peak within the region of 12–13 ppm, suggesting competition for hydrogen bonding with LOR between TEA and RH40. The optimized formulation (4% TEA, 0% RH40, and 0.2% Al(OH)3) increased skin hydration by 6.20-fold. Opposing effects of TEA and RH40 on skin elasticity were observed. Conclusion Expected flux and adhesion strength for the optimized formulation were 7.18 μg·cm–2·h–1 and 11.79 mJ, respectively. Our understanding of the conflicting effects of TEA and RH40 has been advanced. The integrated use of the two-step DoE, physicochemical studies, and skin physiology assessments was proven to be effective in elucidating the simultaneous effects of different permeation-modifying strategies on patches, thus having substantial value for the successful execution of future research endeavors.
ROBUST TRAFFIC LIGHT DETECTION AND CLASSIFICATION UNDER DAY AND NIGHT CONDITIONS
Phuc Manh Nguyen,Vu Cong Nguyen,Son Ngoc Nguyen,Linh My Thi Dang,Ha Xuan Nguyen,Vinh Dinh Nguyen 제어로봇시스템학회 2020 제어로봇시스템학회 국제학술대회 논문집 Vol.2020 No.10
Recently, traffic light detection and classification systems have been studied and developed to build an autonomous car by many research institutes, universities, and companies. However, the results of existing traffic light detection systems are still not stable under day and night conditions. It is difficult to detect the location of traffic light due to their small size. Moreover, traffic lights’ shapes are also similar to advertisement lights in a city road. Therefore, this paper proposed a new approach to improve the performance of existing traffic light detection systems by using the benefits of hand-crafted features and deep learning techniques. Experimental results show that the proposed system obtained the detection rate of 80% under night conditions, while the color-based density method only got the detection rate of 50.43% under night conditions.
Determinants Influencing Information Transparency in Vietnamese Commercial Banks
NGUYEN, Minh Phuong,NGUYEN, Thi Hong Hai,HOANG, Phuong Dung,TRAN, Manh Dung,PHAM, Quang Trung Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.12
Information transparency ensures that market players all have the opportunity to access the same information to come up with their assessment of the banks' financial situation, performance and risks to reach effective investment decisions. This research is conducted to investigate the levels of impact of determinants on information transparency by examining the case studies of Vietnamese commercial banks. This study combines both qualitative and quantitative research methods, based on interviews of 32 specialists in banking, accounting and auditing fields, which were conducted to explore determinants influencing information transparency and to develop measurement scales. Then, a survey of 160 managers of commercial banks, audit firms, and accounting managers of firms who frequently had transactions with banks was carried out to investigate the statistical significance of these determinants. The results show that, out of seven determinants that have significant impacts on the banks' information transparency, commitment from banks' senior management regarding transparency in information disclosure has the highest impact, followed by state governance, auditing, information infrastructure, credit rating agencies, personnel and bank performance. Accordingly, we provide some recommendations for improving information transparency in the Vietnamese banking industry context as a case study and in emerging countries context in general.
Nguyen Thi Mai Tho,Bui The Huy,Dang Nguyen Nha Khanh,Ho Nguyen Nhat Ha,Vu Quang Huy,Ngo Thi Tuong Vy,Do Manh Huy,Duong Phuoc Dat,Nguyen Thi Kim Phuong 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.12
Novel highly active visible-light photocatalysts in the form of zinc bismuth oxide (ZnBi2O4) and graphite hybrid composites were prepared by coupling via a co-precipitation method followed by calcination at 450 oC. The asprepared ZnBi2O4-graphite hybrid composites were tested for the degradation of rhodamine B (RhB) solutions under visible-light irradiation. The existence of strong electronic coupling between the two components within the ZnBi2O4- graphite heterostructure suppressed the photogenerated recombination of electrons and holes to a remarkable extent. The prepared composite exhibited excellent photocatalytic activity, leading to more than 93% of RhB degradation at an initial concentration of 50mg·L1 with 1.0 g catalyst per liter in 150min. The excellent visible-light photocatalytic mineralization of ZnBi2O4-1.0graphite in comparison with pristine ZnBi2O4 could be attributed to synergetic effects, charge transfer between ZnBi2O4 and graphite, and the separation efficiency of the photogenerated electrons and holes. The photo-induced h+ and the superoxide anion were the major active species responsible for the photodegradation process. The results demonstrate the feasibility of ZnBi2O4-1.0graphite as a potential heterogeneous photocatalyst for environmental remediation.
Resource Allocation for Epidemic Network under Complications
Nguyen Manh Hung,Quoc Van Tran,Ji Liu,Hyo-Sung Ahn 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10
In this work, we study the optimal resource allocation to control an epidemic outbreak in a network of population. In particular, we utilize a Susceptible-Infected-Complicated-Susceptible (SICS) model in which complication phenomena is considered. Due to the limitation of the resources, the epidemic is modelled with two levels of recovery rate: one associated with people under medical treatment and the other associated with people who can get rid of the disease by themselves. The resource allocation is considered in these two cases as well. The problem is formulated as a Geometric Program with budget constraint and rate constraint. We illustrate the performance of our approach through numerical simulations.
Manh-Cuong Nguyen,An Hoang-Thuy Nguyen,Hyungmin Ji,Sujin Choi,Jonggyu Cheon,Kyoung-Moon Yu,Seong-Yong Cho,Jin-Hyun Kim,Sang-Woo Kim,Rino Choi 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.73 No.5
The trap energy profile of top gate In-Ga-Zn-O (IGZO) thin film transistors was extracted suc- cessfully using a transmission line model incorporating the conductance method. By implementing the transmission line model method into the conventional conductance method, we were able to evaluate the contact resistance and the channel length modulation precisely and to decouple them to obtain the intrinsic channel conductance. The observed conductance over the angular frequency was almost perfectly symmetrical, which is observed only in the ideal conductance method. Finally, a shallow trap profile, including the trap density and time constant near the conduction band edge of IGZO, was extracted successfully.
Nguyen, Manh-Cuong,Nguyen, An Hoang Thuy,Ji, Hyungmin,Cheon, Jonggyu,Kim, Jin-Hyun,Yu, Kyoung-Moon,Cho, Seong-Yong,Kim, Sang-Woo,Choi, Rino Institute of Electrical and Electronics Engineers 2018 IEEE transactions on electron devices Vol. No.
<P>A novel single-pulse charge pumping (SPCP) method was proposed and implemented to profile the density of states (DOSs) in metal–oxide–semiconductor thin-film transistors (TFTs). The proposed SPCP method was demonstrated in characterizing the DOS below the conduction band of indium gallium zinc oxide TFTs. The DOSs, including oxygen vacancy donorlike states and band tail states, were characterized successfully with high resolution. This method has all the advantages of the conventional CP method and single-pulse characterization.</P>
Tidal Farming Optimization around Jangjuk-sudo by Numerical Modelling
Nguyen, Manh Hung,Jeong, Haechang,Kim, Bu-Gi,Yang, Changjo Korean Society for Fluid machinery 2016 한국유체기계학회 논문집 Vol.19 No.4
This study presents an approach of tidal farming optimization using a numerical modelling method to simulate tidal energy extraction for 1MW scale tidal stream devices around Jangjuk-sudo, South Korea. The utility of the approach in this research is demonstrated by optimizing the tidal farm in an idealized scenario and a more realistic case with three scenarios of 28-turbine centered tidal array (named A, B and C layouts) inside the Jangjuk-sudo. In addition, the numerical method also provides a pre-processing calculation helps the researchers to quickly determine where the best resource site is located when considering the position of the tidal stream turbine farm. From the simulation results, it is clearly seen that the net energy (or wake energy yield which includes the impacts of wake effects on power generation) extracted from the layout A is virtually equal to the estimates of speed-up energy yield (or the gross energy which is the sum of energy yield of each turbine without wake effects), up to 30.3 GWh/year.