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      • 집적회로화된 압력감지기

        이문기 연세대학교 산업기술연구소 1984 논문집 Vol.16 No.2

        The design and fabrication of a small high frequency piezoresistive silicon pressure transducer are presented in this paper. Analyses of stress patterns and vibrational characteristics of the sensor diaphragm are performed. A transducer is designed with diaphragm dimensions of 0.03″×0.05″×6.3㎛ to have a 150 KHz first mode natural frequency, the overall transducer dimensions are 0.05″×0.08″×0.008″. Measurements of the sensor's first mode natural frequency are made with a shock tube test apparatus. The natural frequency of the sensor is found to be 150KHz, as predicted. Sensitivity measurements are also made on the transducer. The sensor's performance at both high (13.5psi) and low (0.001psi) pressure levels indicates a sensitivity of approximately 1.8mV/V/psi as compared to the calculated value of 1.56mV/V/psi. Testing of the transducer's frequency response over a continuous range of frequencies is carried out in an anechoic chamber. The transducer's response remains flat within ±1.5dB over the entire range of test frequencies(1-16KHz). The tests results demonstrate a silicon piezoresistive pressure transducer can be fabricated to make measurements of high frequency low pressure profiles. The achievable first mode natural frequency and the sensitivity may be 1 MHz and ?? psi, respectively.

      • Personal Computer를 이용한 반주문형 집적 회로 설계용 Workstation

        이문기,이석호,김승환 연세대학교 산업기술연구소 1987 논문집 Vol.19 No.2

        LEDISO는 레이아웃을 설계하기 위한 소프트웨어이며, 하드웨어 구성에 따르는 LEDISO의 하드웨어 의존성을 줄이기 위하여 그래픽 소프트웨어 표준인 GKS의 환경조건을 이용하였다. LEDISO의 데이타 구조는 CIF 데이타 구조를 기본으로 Polygon, Box, RFlash, Wire, Label 등을 오브젝트(object)로 가지며, Master를 이용한 SFF로 화일 관리를 한다. GKS의 세그먼트(Segment)를 이용한 아이컨(Icon)을 메뉴에 도입하여 시각적으로 사용자 인터페이스에 도움이 되도록 하였다. LEDISO, Layout EDiting SOftware for IC design, is implemented in C language with the environment condition of GKS which is the graphic standard software in order to reduce the hardware dependency. The data structure of LEDISO with the base of CIF data structure has the object as polygon, box, rflash, wire and label, managing files as SFF using the Master. In order to help user, the menu consisted of string and icon which has the segment of GKS is adopted in LEDISO.

      • KCI등재

        창의적 사고력 신장을 위한 고등학교 국사 교과서 <심화 과정>의 분석

        이문기,남한호 경북대학교 사범대학부속 중등교육연구소 2003 중등교육연구 Vol.51 No.2

        The purpose of this study is to find a more effective way to develop and encourage historical and creative thought among high-school students studying history. 7th national curriculum focuses on the importance of understanding core knowledge, acquiring inquiry skills and encouraging higher -level thought. But, the Korean history textbook and 'advanced course' currently used in high school focuses mainly on picking up facts, and simply reading given materials limits the development of historical and creative thinking. 'Advanced course' in the subject, while curriculum differentiation on the basis of students' academic characteristics is applied, is good for developing higher level thinking, that is, historical thinking and creative thinking, as it enhances the achievement of students, who reach basic achievement level, on the same or expanded status of the subject.

      • KCI등재

        甘豆湯煎湯液이 순환기 Anaphylaxis에 미치는 影響

        李柱憲,文炳淳,李基商 대한동의병리학회 1998 동의생리병리학회지 Vol.12 No.1

        Anaphylaxis는 無防禦란 뜻으로 抗原刺戟에 의하여 감작된 生體가 일정기간 후에 동일한 抗原과 接觸했을 때 수분에서 수십분 내에 급격히 증상을 나타내는 현상이다. 甘豆湯은 甘草·黑豆 二味로 구성되어 있으며 甘草는 和中하여 해독작용이 있고, 약리학적으로 혈압상승작용, 抗allergy 작용, histamine과 같은 allergy를 일으키는 物質의 血管 透過性 억제, 心血虛에 의한 不整脈, 動悸에 效果가 있다고 알려져 있다. 黑豆는 散熱하여 해독하는 작용이 있고, 예로부터 黑豆만 사용했을 때 보다 甘草를 加하여 사용했을 때 탁월한 해독효과가 있다고 하였다. 따라서 本 方은 각종 allergy 반응을 일으키는 特定物質에 대한 해독작용과 抗allergy 작용이 있으므로 순환기 anaphylaxis에 效果가 있을 것으로 생각되어, pithed rat에서의 순환기 anaphylaxis 반응에 미치는 效果, guinea pig 심장에서의 anaphylaxis 반응에 미치는 效果, guinea pig의 기관지평활근에 미치는 效果, rat의 PCA 반응에 미치는 效果에 대한 실험을 觀察하여 有意性 있는 다음과 같은 結果를 얻었다. 甘豆湯煎湯液은 in vivo model인 pithed rat에서 순환기 anaphylaxis을 저해하는 작용이 있으며 anaphylaxis에 의한 動物의 치사율을 현저하게 억제하였고, pithed rat에서 지속적인 혈압하강을 有意性있게 억제하였으나 頻脈현상을 차단하지는 못하였다. 甘豆湯煎湯液은 guinea pig 심장에서 anaphylaxis에 의한 심장기능의 부전을 차단하지 못하였고, guinea pig의 기관지평활근에서 LTD₄, histamine, 5-HT 등으로 유발한 수축현상을 억제하지 않았으나, rat에서의 PCA 반응을 有意性있게 억제하였다. 以上의 結果로 보아 甘豆湯煎湯液은 순환기 anaphylaxis를 포함한 type Ⅰ allergy현상을 차단하는 效能이 있으며 이는 직접적으로 anaphylaxis에 관여하는 매개물질을 길항하기 보다는 이들 매개물의 생합성을 차단하거나 肥滿細胞로부터의 遊離를 차단할 가능성이 있다. 따라서 이러한 순환기 anaphylaxis 차단작용은 심장보다 말초혈관에서의 혈관이완이 주 작용으로 보여진다 This study was investigated the inhibitory activity of Gamdutang water extract on type Ⅰ immediate hypersensitivity of anaphylatic type. The results of this study were as follows: 1. Gamdutang water extract ameliorated the cardiovascular anaphylactic response and thus reduced lethality in the vivo rat model (pithed rat). 2. The ameliorating effect was related to the blunting of sustained depressor effect appeared follwing antigen challenge, but the tachycardic response was not influenced. 3. In the isolated guinea pig heart, Gamdutang water extract did not prevent the occurrence of cardiac failure induced by anaphylaxis. 4. Gamdutang water extract did not relax the contractility response of isolated guinea pig trachea to LTD4, histamine or 5-HT. This result indicates that te Gamdutang water extract does not possess direct inhibitory action on these major anaphylactic mediators. 5. Gamdutang water extract could be effective against other types of anaphylaxis since the substance was effective in PCA test. The results suggest that Gamdutang water extract is effective in preventing Type Ⅰ allergy such as anaphylaxis. Gamdutang water extract may not antagonized directly major anaphylactic mediators such as LDT4, histamine or 5-HT. Rather it seems that Gamdutang water extract interferes the release of these mediators from mast cells in the advent of anaphylaxis, or it may inhibit the biosynthesis of these substances. Gamdutang water extract's main site of action seems to be peripheral resistance vessels, not the heart.

      • KCI등재후보
      • SCOPUSKCI등재

        $^{18}F$-FDG Uptake of Human Testis on PET/CT: Correlation with Age, Sex Hormones, and Vasectomy

        Moon, Seung-Hwan,Eo, Jae-Sun,Lee, Jong-Jin,Chung, June-Key,Lee, Dong-Soo,Lee, Myung-Chul The Korea Society of Nuclear Medicine 2011 핵의학 분자영상 Vol.45 No.4

        Purpose The purpose of this study was to evaluate glucose metabolism of normal human testis on $^{18}F$-FDG PET/CT and to assess possible correlations among age, the serum levels of sex hormones, and vasectomy. Methods $^{18}F$-FDG PET/CT was performed in 66 normal healthy men ($50.8{\pm}13.6$ years, range 22-81), and mean standard uptake values (SUV) of $^{18}F$-FDG in testis and adductor muscle were measured. Testis-muscle SUV ratios (T/M ratios) were calculated. Serum levels of total testosterone, free testosterone, estradiol, and of sex-hormone binding globulin (SHBG) were measured. We searched for correlations between T/M ratios and age and the serum concentrations of sex hormones. $^{18}F$-FDG PET/CT was also performed in 32 vasectomized men ($55.7{\pm}7.8$ years, range 38-71) and 52 nonvasectomized men ($55.4{\pm}11.6$ years, range 37-72). Mean SUVs of testis and adductor muscle were measured, and T/M ratios were calculated. Results A significant age-related decline was found in T/M ratio (r=-0.509, p<0.0001). Serum levels of total testosterone and free testosterone were also found to be positively correlated with T/M ratio (r=0.427, p=0.0003; r=0.435, p=0.0003, respectively). The mean SUVand T/M ratio of vasectomized men were significantly lower than those of nonvasectomized men (p<0.0378 and p=0.0001, respectively). Conclusions Glucose metabolism in the testis in an adult population was found to be correlated with age, serum sex hormone level, and vasectomy history. These results indicate that testicular $^{18}F$-FDG uptake may have attributed to testicular function and testicular histology. Our findings may have important implications for the interpretation of testicular $^{18}F$-FDG uptake in the normal adult population.

      • HDL Modeling of a Branch Target Buffer for High Performance Microprocessor Applications

        Lee,Moon Key,Lee,Yong Surk,Sonh.Seung Il THE RESEARCH INSTITUTE OF ASIC DESIGN YONSEI UNIVE 1995 Journal of the Research Institute of ASIC Design Vol.2 No.1

        Efficient executions of branch instructions are one of the most important issues in implementing high performance microprocessors. Branching instructions are above 20% of total instruction in most programs. BTB( Branch Target Buffer ) enhances the speed of branch instruction execution by predicting the branch path, including currently executed branch instruction address, prediction information, and target address. In this paper, we describe and verify a HDL model of the BTB for a high performance microprocessor. The BTB is designed as a 4 - way set associative organization with 256 branch entries. Pseudo-LRU algorithm is used for replacement of lines instead f ordinary LRU algorithm. Two history information bits are used to hold prediction state, with transitions between the four states occuring when a branch is encounted.

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