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Korean Clinical Practice Guidelines: Current Status of Adherence to the RIGHT Checklist
Choi Miyoung,Lee You Kyoung,Kim Soo Young 대한의학회 2022 Journal of Korean medical science Vol.37 No.4
Background: The Korean Academy of Medical Sciences (KAMS) has been utilizing AGREE II to audit the quality of clinical practice guidelines (CPGs) developed in Korea. Monitoring the RIGHT Checklist adherence could help monitor the quality status and discover areas for improvement of CPG development. Methods: We included 129 CPGs from the past 5 years and assessed each item of the RIGHT Checklist. STATA version 15.0 was used for statistical analysis. Results: Among the seven sections of the RIGHT checklist, sections with a full compliance rate over 60% were ‘basic information’ (65%) and ‘background’ (66%). The other sections’ mean full compliance rates were ‘Evidence’ 52%, ‘Recommendation’ 35%, ‘Review and quality assurance’ 25% and ‘Funding, declaration and management of interest’ 17%. Sections with a partial compliance rate over 60% were ‘Recommendation’ (60%) and ‘Funding, declaration and management of interest’ (70%). Non-compliance was highest in the ‘Review and quality assurance’ (17%) domain. In comparison between groups 1 (under median group) and 2 (over median group), group 2 showed a tendency to have multi-stakeholder involvement and present sufficient information on financial resources and conflict of interest declarations. For the CPGs developmental methodology aspect, group 2 provided more pertinent information than group 1 about supporting evidence-making and the process from evidence to recommendation. Conclusion: This study evaluated adherence to the RIGHT Checklist of CPGs developed in Korea. It can provide helpful information to develop strategic plans for enhancing the capabilities of developing CPGs in Korea.
Current Status of Clinical Practice Guidelines in Korea
Choi Miyoung,김수영,Lee You Kyung,Executive Committee for Clinical Practice Guidelines, The Korean Academy of Medical Sciences 대한의학회 2021 Journal of Korean medical science Vol.36 No.6
Background: The development process of clinical practice guidelines (CPGs) must adhere to development standards and must be supported and steered by a representative and consistent governing body. We aimed to investigate the current status of the most recent CPGs published in Korea through surveys of medical professional societies and literature searches. Methods: We collected CPGs developed in Korea in the past 5 years through several electronic database searches (MEDLINE, Embase, and KoreaMed), hand searches, and surveys of medical society memberships from the Korean Academy Medical Societies. Three authors selected Korean CPGs according to our inclusion/exclusion criteria and extracted data from selected CPGs about general characteristics, characteristics of CPGs for setup, evidence evaluation, and the finalization phase. Results: Out of 2,337 articles searched from various sources and 66 documents collected by survey, 129 guidelines (122 by database searching and 7 by survey) were selected. During the recent 5 years, the yearly numbers of CPGs developed were around 25. A single organization was the most frequent CPG development body (42, 32.6%). The most common development methodologies described in the CPGs included were de novo (53, 41.1%) followed by adaptation (48, 37.2%) and hybrid (4, 3.1%). Systematic literature searching was performed in most of the guidelines (79.8%). The evidence level was reported in 104 guidelines (80.6%). There were 77 guidelines (59.7%) that reported an update plan. Fifty guidelines were published in Korean (41.0%), and 46 guidelines were published in English only (37.7%). Conclusion: Among CPGs developed in Korea in the last 5 years, the proportion adhering to CPG development standards has increased, but there is still room for improvement.
Kim, Jung-Ah,Han, Gi-Chun,Lim, Mihee,You, Kwang-Suk,Ryu, Miyoung,Ahn, Ji-Whan,Fujita, Toyohisa,Kim, Hwan Molecular Diversity Preservation International (MD 2009 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.10 No.11
<P>Wt% of aragonite, a CaCO<SUB>3</SUB> polymorph, increased with higher hydraulic activity (°C) of limestone in precipitated calcium carbonate (PCC) from the lime-soda process (Ca(OH)<SUB>2</SUB>-NaOH-Na<SUB>2</SUB>CO<SUB>3</SUB>). Only calcite, the most stable polymorph, was crystallized at hydraulic activity under 10 °C, whereas aragonite also started to crystallize over 10 °C. The crystallization of PCC is more dependent on the hydraulic activity of limestone than CaO content, a factor commonly used to classify limestone ores according to quality. The results could be effectively applied to the determination of polymorphs in synthetic PCC for eco-friendly paper manufacture.</P>
Anion Extraction-Induced Polymorph Control of Transition Metal Dichalcogenides
Nam, Dae-Hyun,Kim, Ji-Yong,Kang, Sungwoo,Joo, Wonhyo,Lee, Seung-Yong,Seo, Hongmin,Kim, Hyoung Gyun,Ahn, In-Kyoung,Lee, Gi-Baek,Choi, Minjeong,Cho, Eunsoo,Kim, Miyoung,Nam, Ki Tae,Han, Seungwu,Joo, You American Chemical Society 2019 NANO LETTERS Vol.19 No.12
<P>Controlled phase conversion in polymorphic transition metal dichalcogenides (TMDs) provides a new synthetic route for realizing tunable nanomaterials. Most conversion methods from the stable 2H to metastable 1T phase are limited to kinetically slow cation insertion into atomically thin layered TMDs for charge transfer from intercalated ions. Here, we report that anion extraction by the selective reaction between carbon monoxide (CO) and chalcogen atoms enables predictive and scalable TMD polymorph control. Sulfur vacancy, induced by anion extraction, is a key factor in molybdenum disulfide (MoS<SUB>2</SUB>) polymorph conversion without cation insertion. Thermodynamic MoS<SUB>2</SUB>-CO-CO<SUB>2</SUB> ternary phase diagram offers a processing window for efficient sulfur vacancy formation with precisely controlled MoS<SUB>2</SUB> structures from single layer to multilayer. To utilize our efficient phase conversion, we synthesize vertically stacked 1T-MoS<SUB>2</SUB> layers in carbon nanofibers, which exhibit highly efficient hydrogen evolution reaction catalytic activity. Anion extraction induces the polymorph conversion of tungsten disulfide (WS<SUB>2</SUB>) from 2H to 1T. This reveals that our method can be utilized as a general polymorph control platform. The versatility of the gas-solid reaction-based polymorphic control will enable the engineering of metastable phases in 2D TMDs for further applications.</P> [FIG OMISSION]</BR>