http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Han Hee Jo,Kim Seung Woo,Kim Hyunjin,So Jungmin,Lee Eun-Jae,Lim Young-Min,Lee Jung Hwan,Lee Myung Ah,Kim Byung-Jo,Baek Seol-Hee,Lee Hyung-Soo,Sohn Eunhee,Kim Sooyoung,Park Jin-Sung,Kang Minsung,Park H 대한의학회 2024 Journal of Korean medical science Vol.39 No.18
Background: During the coronavirus disease 2019 (COVID-19) pandemic, patients with myasthenia gravis (MG) were more susceptible to poor outcomes owing to respiratory muscle weakness and immunotherapy. Several studies conducted in the early stages of the COVID-19 pandemic reported higher mortality in patients with MG compared to the general population. This study aimed to investigate the clinical course and prognosis of COVID-19 in patients with MG and to compare these parameters between vaccinated and unvaccinated patients in South Korea. Methods: This multicenter, retrospective study, which was conducted at 14 tertiary hospitals in South Korea, reviewed the medical records and identified MG patients who contracted COVID-19 between February 2022 and April 2022. The demographic and clinical characteristics associated with MG and vaccination status were collected. The clinical outcomes of COVID-19 infection and MG were investigated and compared between the vaccinated and unvaccinated patients. Results: Ninety-two patients with MG contracted COVID-19 during the study. Nine (9.8%) patients required hospitalization, 4 (4.3%) of whom were admitted to the intensive care unit. Seventy-five of 92 patients were vaccinated before contracting COVID-19 infection, and 17 were not. During the COVID-19 infection, 6 of 17 (35.3%) unvaccinated patients were hospitalized, whereas 3 of 75 (4.0%) vaccinated patients were hospitalized (P < 0.001). The frequencies of ICU admission and mechanical ventilation were significantly lower in the vaccinated patients than in the unvaccinated patients (P = 0.019 and P = 0.032, respectively). The rate of MG deterioration was significantly lower in the vaccinated patients than in the unvaccinated patients (P = 0.041). Logistic regression after weighting revealed that the risk of hospitalization and MG deterioration after COVID-19 infection was significantly lower in the vaccinated patients than in the unvaccinated patients. Conclusion: This study suggests that the clinical course and prognosis of patients with MG who contracted COVID-19 during the dominance of the omicron variant of COVID-19 may be milder than those at the early phase of the COVID-19 pandemic when vaccination was unavailable. Vaccination may reduce the morbidity of COVID-19 in patients with MG and effectively prevent MG deterioration induced by COVID-19 infection.
원형 실린더가 존재하는 사각 밀폐계 바닥면의 고온 영역 변화가 자연대류 현상에 미치는 영향
조현우(Hyun Woo Jo),윤현식(Hyun Sik Yoon),이효정(Hyo Jeong Lee),김민성(Minsung Kim),하만영(Man Yeong Ha) 대한기계학회 2013 大韓機械學會論文集B Vol.37 No.11
본 연구에서는 Ra =10? 일 때, 사각 밀폐계 내부에 고온의 원형 실린더가 존재하는 자연대류에 대한 수치해석을 수행하였다. 밀폐계는 상부 벽면을 통해 냉각되고 양측 벽면과 고온의 국소 영역을 제외한 하부 벽면은 단열 조건이다. 하부 벽면에서 고온 영역이 차지하는 비를 w 로 정의 하였다. 반경이 밀폐계 한 변의 길이의 0.2 배인 원형 실린더를 구현하기 위해 유한체적법(FVM)에 기초한 가상경계법(IBM)을 사용하였다. 본 연구에서는 w 가 고온의 원형 실린더를 갖는 밀폐계 내부의 자연대류에 미치는 영향을 10?의 Rayleigh 수에 대해 2 차원 해를 구하였다. 10?의 Rayleigh 수에서는 유동장과 온도장은 시간에 따라 변하는 특성을 보였다. A numerical study is carried out for natural convection in an enclosure with an inner hot cylinder at the center. The top wall is cold, the bottom and both side walls of the enclosure are adiabatic, and the cylinder is heated. The bottom wall is heated locally at the middle. The ratio ( w ) is defined by as the width of the bottom wall to that of the heated local area. The immersed boundary method (IBM) is used to model an inner circular cylinder based on the finite volume method (FVM). This study investigates the effect of w on natural convection in an enclosure with an inner heated cylinder for Rayleigh numbers of 10?. At Ra = 10?, thermal and flow fields show time-dependent characteristics after their full development.
Recent registration of microbial pesticides: Fungi-based insecticides
Jae Su Kim,Mi Rong Lee,Jong Cheol Kim,Sihyeon Kim,So Eun Park,Dongwei Li,Sehyeon Baek,Minsung Jo,Tae Young Shin,Leila Gasmi,Junheon Kim 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.04
The serious emergence of chemical-mediated residual toxicity and insect resistance have been enforced the regulation of synthetic pesticides. Future decisions to select more realistic control options probably depend on the speed of technological development in chemical and biological pesticides. Now, a strategic collaboration between synthetic pesticides and biopesticides has been progressed, such as distribution and R&D in collaboration and M&A for obtaining microbial resources. Recently registered microbial pesticides are entomopathogenic fungi in pest management. A concept of e-biopesticide could be properly combined with digital agriculture and accelerate the use of biological control agents in the future farming.