http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Takaya, Makiko,Nomura, Masaaki,Takahashi, Tatsuo,Kondo, Yoko,Lee, Kyung-Tae,Kobayashi, Shinjiro Potamitis Press 2009 Anticancer research Vol.29 No.4
<P>BACKGROUND: There are few reports on the biological activities of 23-hydroxyursolic acid (23-HUA). The mechanism of growth-inhibition induced by 23-HUA, isolated from Cussonia bancoensis, in human cervical squamous carcinoma HeLa cells is hereby investigated. MATERIALS AND METHODS: The growth-inhibitory activity was measured by MTS assay. Caspases activation and expression of apoptosis-related proteins were detected by Western blotting. Apoptotic cells were observed by morphological analysis with Hoechst 33342. RESULTS: 23-HUA inhibited the growth of HeLa cells in a concentration dependent manner. Proteolytically generated fragments of caspase-3, -8 and -9 were observed in HeLa cells treated with 60 microM 23-HUA. The expression of Bcl-X(L), an anti-apoptotic protein, was markedly decreased by 60 microM 23-HUA. Morphological analysis showed that apoptotic changes occurred after treatment with 60 microM 23-HUA, and the changes were inhibited by a pan-caspase inhibitor, Z-VAD-FMK. CONCLUSION: These results indicate that 23-HUA causes potent growth-inhibition by the induction of apoptosis via activation of caspases in HeLa cells.</P>
Real-time Monitoring System for Container Networks in the Era of Microservices
Naoki Oguchi,Yosuke Takano,Reiko Kondo,Masaaki Noro,Takashi Shiraishi 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09
Large-scale web services are increasingly adopting the microservice architecture that mainly utilizes container technologies. Microservices are operated on complex configured infrastructures, such as containers, virtual machines, and physical machines. To ensure service quality of microservices, it is important to monitor not only the quality of services but also the quality of the infrastructures utilized by the services. Therefore, the metrics of the infrastructure related with the services should be traced. An extended Berkeley Packet Filter (eBPF) is a relatively new Linux’s function, which is effectively used as a sensor of container-network metrics. There are two key challenges in realizing the service-linked monitoring system. One challenge is making the full-stack topology between microservices, containers, and machines visible to set the sensor related with the services. Another challenge is dynamic sensor management that can relocate the sensor quickly after the topology’s change. In this paper, we propose a real-time monitoring system that creates a full-stack topology and relocates the sensor in conjunction with events from a container orchestrator. The system enables a dynamic deployment of the sensors related with the monitored services.