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Mahmoud Ibrahim,Sulaiman Nabil,Hussein Amal,Mohammed Heba,AL Nakhi Wafa Khamis,Hussain Hamid,Ibrahim Gamal 한국역학회 2021 Epidemiology and Health Vol.43 No.-
OBJECTIVES: The aim of this study was to develop a risk score model for predicting hypertension specific to the population of Dubai in the United Arab Emirates (UAE) to facilitate prevention and early intervention. METHODS: A retrospective analysis of data from the Dubai Household Health Survey 2019 was conducted. Demographic and physical parameters, as well as blood glucose levels, were included in the data. The risk factors for hypertension were identified using bivariate analysis. A risk score model was developed using the enter method, where all significant predictors of hypertension in bivariate analyses were entered in a single step with the primary outcome of hypertension status (yes/no). The model was validated internally by splitting the data into Emirati and non-Emirati populations. RESULTS: A total of 2,533 subjects were studied. The significant risk factors for hypertension identified were male sex, older age (≥ 40 years), education level, body mass index, diabetes mellitus, and dyslipidaemia. The model showed a high discrimination ability between individuals with and without hypertension, with an area under the curve of 0.77 (95% confidence interval [CI], 0.75 to 0.79), excellent sensitivity (81.0%; 95% CI, 71.9 to 88.2) and moderate specificity (56.0%; 95% CI, 45.7 to 65.9). CONCLUSIONS: The model developed by this study is simple, convenient, and based on readily available demographic and medical characteristics. This risk score model could support initial hypertension screening and provide an effective tool for targeted lifestyle counselling and prevention programs.
Mahmoud Ibrahim El-Sayed,Esmat Aly,Amany Mohammed El-Deeb 한국식품과학회 2024 Food Science and Biotechnology Vol.33 No.3
Fermented goat milk samples, processed by adding 0, 2, and 4% carob molasses, and Bifidobacterium bifidum DSMZ or Lactobacillus helveticus CH5, were evaluated for their physicochemical, antioxidative, and sensory properties along with probiotic viability during storage. pH and viscosity gradually decreased over the storage period whereas their values increased with the increased amount of carob molasses. Bifidobacterium bifidum DSMZ or Lactobacillus helveticus CH5 kept higher viable numbers. Lactobacillus helveticus CH5 strain recorded higher viability. Increasing the added amount of carob molasses increased the total phenolic content, which in turn is reflected in the increase in antioxidant activity. Adding carob molasses participated in the partial masking of the goaty flavor and had no significant effect on the product’s acceptability, which was strongly influenced by the progress of cold storage. Therefore, fermented goat milk described by its enhanced physicochemical and antioxidative properties could be obtained by adding carob molasses and probiotics.
Post-pandemic seroprevalence of human influenza viruses in domestic cats
Mahmoud Ibrahim,Ahmed Ali,Joshua B. Daniels,Chang-Won Lee 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.4
The continuous exposure of cats to diverse influenza viruses raises the concern of a potential role of cats in the epidemiology of these viruses. Our previous seroprevalence study of domestic cat sera collected during the 2009 H1N1 pandemic wave (September 2009–September 2010)revealed a high prevalence of pandemic H1N1, as well as seasonal H1N1 and H3N2 human flu virus infection (22.5%, 33.0%, and 43.5%,respectively). In this study, we extended the serosurvey of influenza viruses in cat sera collected post-pandemic (June 2011–August 2012). A total of 432 cat sera were tested using the hemagglutination inhibition assay. The results showed an increase in pandemic H1N1 prevalence(33.6%) and a significant reduction in both seasonal H1N1 and H3N2 prevalence (10.9% and 17.6%, respectively) compared to our previoussurvey conducted during the pandemic wave. The pandemic H1N1 prevalence in cats showed an irregular seasonality pattern in thepost-pandemic phase. Pandemic H1N1 reactivity was more frequent among female cats than male cats. In contrast to our earlier finding, nosignificant association between clinical respiratory disease and influenza virus infection was observed. Our study highlights a highsusceptibility among cats to human influenza virus infection that is correlated with influenza prevalence in the human population.
Fallatah, Mahmoud Ibrahim,Ikram, Mohammed International Journal of Computer ScienceNetwork S 2021 International journal of computer science and netw Vol.21 No.6
Small and Medium Enterprises (SMEs) are increasingly using ERP systems to connect and manage all their functions, whether internally between the different departments, or externally with customers in electronic commerce. However, the selection of the right ERP system is usually an issue, due to the complexities of identifying the criteria, weighting them, and selecting the best system and provider. Because cost is usually important for SMEs, ERP systems based on Cloud Software as a Service (SaaS) has been adopted by many SMEs. However, SMEs face an issue of selecting the right system. Therefore, this paper proposes a fuzziness ranking engine system in order to match the SMEs requirements with the most suitable service provider. The extensive experimental result shows that our approach has better result compared with traditional approaches.
( Mostafa Ibrahim Elshazly ),( Khaled Mahmoud Kamel ),( Reem Ibrahim Elkorashy ),( Mohamed Said Ismail ),( Jumana Hesham Ismail ),( Hebatallah Hany Assal ) 대한결핵 및 호흡기학회 2020 Tuberculosis and Respiratory Diseases Vol.83 No.4
Background: Weaning failure is common in mechanically ventilated patients, and if ultrasound can predict weaning outcome remains controversial. The purpose of this study was to evaluate the diaphragmatic function (thickness and excursion) measured by ultrasound as a predictor of the extubation outcome. Methods: We included 62 mechanically ventilated patients from the chest intensive care unit in this study. Sixty-two patients who successfully passed the spontaneous breathing trial (SBT) were enrolled. The transthoracic ultrasound of the diaphragm was performed during an SBT to the assess diaphragmatic function (excursion and thickness), and they were classified into the successful extubation group and the failed extubation group. Results: There was a statistically significant increase in the successful extubation group in the diaphragmatic excursion and thickness fraction (p<0.001), a statistically significant negative correlation between the diaphragmatic function and the duration of the mechanical ventilation, and a statistically significant negative correlation between the diaphragmatic excursion and the Acute Physiology and Chronic Health Evaluation II. The diaphragmatic excursion cutoff value predictive of weaning was 1.25 cm, with a specificity of 82.1% and a sensitivity of 97.1% respectively, and the diaphragmatic thickness cut-off value predictive of weaning was 21.5%, with a specificity of 60.7% and a sensitivity of 91.2%, respectively. Conclusion: The diaphragmatic ultrasonography was found to be a promising tool for predicting the extubation outcome for mechanically ventilated patients.
Salem, Mohamed Mahmoud Ibrahim,Amin, Amin Mohamed Said,Ashour, Ayman Fouad,Ibrahim, Mohamed Mohamed El-said,Abo-Ismail, Mohammed Kotb Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.1
Objective: The objectives of the current study were to study the main environmental factors affecting birth weight (BW) and weaning weight (WW), estimate variance components, genetic parameters and genetic trend and to evaluate the variability and relationships among breeding value of BW and WW using principal components analysis (PCA). Methods: A total of 16,370 records were collected from 8,271 buffalo calves. Genetic parameters and breeding values were estimated using a bivariate animal model which includes direct, maternal and permanent maternal effects. These estimates were standardized and used in PCA. Results: The direct heritability estimates were 0.06 and 0.41 for BW and WW, respectively whereas direct maternal heritability values were 0.03 and 0.14, respectively. Proportions of variance due to permanent environmental effects of dam were 0.455 and 0.280 for BW and WW respectively. The genetic correlation between BW and WWs was weak approaching zero, but the maternal correlation was 0.26. The first two principal components (PC1 and PC2) were estimated utilizing the standardized breeding values according to Kaiser method. The total variance explained by the first two PCs was 71.17% in which 45.91% and 25.25% were explained by PC1 and PC2, respectively. The direct breeding values of BW were related to PC2 but those of WW and maternal breeding values of BW and WWs were associated with PC1. Conclusion: The results of genetic parameters and PCA indicate that BW and WWs were not genetically correlated and improving growth traits of Egyptian buffaloes could be achieved using WW without any adverse effect by BW.
Yacoub, Haitham Ahmed,Mahmoud, Wael Mahmoud,El-Baz, Hatim Alaa El-Din,Eid, Ola Mohamed,ELfayoumi, Refaat Ibrahim,Elhamidy, Salem Mohamed,Mahmoud, Maged M. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. Materials and Methods: This study investigated alterations in the displacement loop (d-loop) region of mitochondrial DNA (mtDNA) as a risk factor and diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia. Using mtDNA from 23 subjects diagnosed with acute lymphoblastic leukemia, the first 450 bp of the d-loop region were amplified and successfully sequenced. Results: This revealed 132 mutations at 25 positions in this region, with a mean of 6 alterations per subject. The d-loop alterations in mtDNA in subjects were all identified as single nucleotide polymorphisms in a homoplasmic distribution pattern. Mutant alleles were observed in all subjects with individual frequency rates of up to 95%. Thirteen mutant alleles in the d-loop region of mtDNA occurred with a high frequency. Novel alleles and locations were also identified in the d-loop of mtDNA as follows: 89 G insertions (40%), 95 G insertions (13%), 182 C/T substitutions (5%), 308 C insertions (19%), and 311 C insertions (80%). The findings of this study need to be replicated to be confirmed. Conclusions: Further investigation of the relationship between mutations in mitochondrial d-loop genes and incidence of acute lymphoblastic leukemia is recommended.
Yacoub, Haitham Ahmed,Mahmoud, Wael Mahmoud,El-Baz, Hatim Alaa-Eldeen El-Din,Eid, Ola Mohamed,El-Fayoumi, Refaat Ibrahim,Mahmoud, Maged Mostafa,Harakeh, Steve,Abuzinadah, Osama H.A. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. Aim and Objectives: This study investigated substitutions in the ATP synthase subunit 6 gene of mitochondrial DNA (mtDNA) as a potential diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia. Based on mtDNA from 23 subjects diagnosed with acute lymphoblastic leukemia, approximately 465 bp of the ATP synthase subunit 6 gene were amplified and sequenced. Results: The sequencing revealed thirty-one mutations at 14 locations in ATP synthase subunit 6 of mtDNA in the ALL subjects. All were identified as single nucleotide polymorphisms (SNPs) with a homoplasmic pattern. The mutations were distributed between males and females. Novel haplotypes were identified in this investigation: haplotype (G) was recorded in 34% in diagnosed subjects; the second haplotype was (C) with frequency of 13% in ALL subjects. Neither of these were observed in control samples. Conclusions: These haplotypes were identified for the first time in acute lymphoblastic leukemia patients. Five mutations able to change amino acid synthesis for the ATP synthase subunit 6 were associated with acute lymphoblastic leukemia. This investigation could be used to provide an overview of incidence frequency of acute lyphoblastic leukemia (ALL) in Saudi patients based on molecular events.
Elliptic Trailing Edge for a High Subsonic Turbine Cascade
Mahmoud M. El-Gendi,Mohammed K. Ibrahim,Koichi Mori,Yoshiaki Nakamura 한국항공우주학회 2008 한국항공우주학회 학술발표회 논문집 Vol.- No.-
The flow through a turbine cascade was numerically simulated for an exit isentropic Mach number of 0.79 and a Reynolds number of 2.8 × 10? The objective of the present study is to improve the base pressure distribution at this high subsonic Mach number. Calculation was carried out using the in-house numerical code, where the 2<SUP>nd</SUP> order Roe scheme for inviscid numerical fluxes. the 2<SUP>nd</SUP> order implicit dual lime method for time integration, and Delayed Detached Eddy Simulation for turbulence are employed. Time-averaged pressure distributions through the cascade have been presented with more attention paid to the trailing edge region. Calculated results show the non-uniform pressure distribution along the trailing edge, which is close to experimental data and different from almost uniform pressure distributions at moderate subsonic Mach numbers. To improve the trailing edge pressure distribution, we use an elliptic trailing edge instead of a circular one as a proposal for a new, practical trailing edge shape. The elliptic trailing edge make not only the trailing edge pressure distribution uniform but also increase the average base pressure by 5.26%.