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RISS 인기검색어
- 검색키워드
- 저자 : Leila Mounesan (검색결과 2 건)
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The prevalence of Q fever in the Eastern Mediterranean region: a systematic review and meta-analysis
Ahmadinezhad Mozhgan,mounesan leila,Doostiirani Amin,Yousefi Behzadi Manijeh 한국역학회 2022 Epidemiology and Health Vol.44 No.-
OBJECTIVES: Q fever is a main zoonotic disease around the world. This disease is common in the Eastern Mediterranean region, so we conducted for the first time a systematic review and meta-analysis between humans and animals and ticks in the Eastern Mediterranean region. METHODS: Major national and international databases were searched from 2000 up to 2021. We extracted the prevalence of Q fever in a blood sample in animal, milk sample in animal, tick, and human as the main outcome. We reported the prevalence of seropositivity and molecular positivity as point and 95% confidence intervals. RESULTS: In this review, 112 papers were identified. The overall seroprevalence Q fever was 22.4% (95% CI 19.8–25.1). The pooled prevalence of Q fever in tick was 17.5% (95% CI -1.3-36.4). The prevalence was 25.5%( 95% CI 16.1-34.9) in human. The prevalence of Q fever in animal blood samples such as goat, sheep, camel, cattle, dog, cat, buffalo, and horse were 28.1%, 25.1%, 25.0%, 20.1%, 8.4%, 9.8%, 6.3%, and 6.5%, respectively. Also, the prevalence of Q fever in milk samples of animals was higher in cattle 20.3% than sheep 20.0%, goat 16.4%, and camel 3.3%. CONCLUSIONS: C.burnetii infections are common in human and in a wide range of animal species but they are still not recognized in many countries in the Eastern Mediterranean region, thus presenting a significant threat to human and animal health in the region.
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Coronary Artery Calcium Score and Bone Metabolism: A Pilot Study in Postmenopausal Women
Pooneh Salari,Abbasali Keshtkar,Shapour Shirani,Leila Mounesan 대한골대사학회 2017 대한골대사학회지 Vol.24 No.1
Background: Since 1991 many studies evaluated the link between cardiovascular diseases and osteoporosis, two age-related conditions, but the main common pathologic pathway has not been determined yet. The histological similarity between arterial calcified plaque and bone matrix and involvement of similar cells and mediators provide a special field of research. Therefore in the present study, we aimed to evaluate the relationship between coronary artery calcium score (CACS) as a surrogate marker of atherosclerosis and bone mediators and parameters in postmenopausal women. Methods: Eleven postmenopausal women who had CACS higher than 80 were enrolled into the study and underwent bone densitometry. In addition, their serum and urine samples were taken for measuring osteoprotegerin, osteocalcin, and β cross laps. Patients’ 10- year probability of fracture was calculated by the World Health Organization fracturerisk assessment tool (FRAX). Results: The regression analysis of our results showed the association between CACS and OC (std β=0.66, 95% confidence interval [CI] 5.47-72.27, P=0.027), femoral bone density (std β=-0.6, 95% CI -6864.34-14.27, P=0.05) and T-score (std β=-0.6, 95% CI -773.08-1.28, P=0.05) which remained significant after adjustment for age, weight, years since menopause and body mass index. No association was found between CACS and osteoprotegerin, spinal bone density and FRAX score. Conclusions: In conclusion, this pilot study with small sample size showed the potential association between CACS and osteocalcin, femoral bone density and T-score. However, the relationship between CACS and osteoprotegerin, receptor activator of nuclear factor-kappa B ligand, FRAX score and other bone parameters remain to be clarified in larger sample size studies.
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