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A case of cellular fibrous histiocytoma on the palm
( Eun Sun Kwon ),( Byoung Yong Koh ),( Kyong Geun Lee ),( Ki Bum Myung ),( Seung Hyun Cheong ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Dermatofibroma is a common benign skin tumor that usually occurs as small, firm and red to brown solitary or multiple nodules on the lower extremities. In addition to the lower extremities, it can be observed anywhere. But the involvement of palm or sole is rare. Dermatofibroma has various histologic variants. In these variants, cellular fibrous histiocyma is relatively rare and histopathologically exhibits the densely cellular tumor with a fascicular to storiform growth pattern. A 40-year-old man presented with a solitary firm and reddish nodule on the left palm. The biopsy specimen revealed a nodular tumor that composed of spindle cells, histiocytes and collagen bundles. Immunohistochemical stain showed negative for CD 34, S-100 and CK, diffused positive for vimentin and weakly positive for CD68. Also Ki-67 staining showed less than 5% positive reactivity. Herein we describe a case of cellular fibrous histiocytoma on the palm.
Multiple giant keratoacanthoma treated with acitretin
( Eun Sun Kwon ),( Byoung Yong Koh ),( Kyung Geun Lee ),( Ki Bum Myung ),( Seung Hyun Cheong ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Giant keratoacanthoma is an uncommon variant of keratoacanthoma, which may attain the diameter of several centimeters. Although keratoacanthoma usually undergo spontaneous resolution, giant keratoacanthoma can be invasive and destructive. A 49-year-old man presented with a 5-year history of multiple large hyperkeratotic and crusted plaques and nodules on the sun exposed areas such as face, ear, hand and forearm. Some lesions were involuted spontaneoulsy, whereas other lesions were rather enlarged. The biopsy specimen revealed horn-filled crater formation, epidermal extending like a buttress and eosinophilic glassy appearance in kertinocytic cytoplasm. In immunohistochemical stain, the Ki-67 staining was restricted to the basal layer. And p16 staining occurred more diffuse pattern. We treated them with acitretin and the lesions were almost cleared after 13 weeks. Herein we describe a case of multiple giant keratoacanthoma treated with acitretin.
Bowen`s disease originated from verruca
( Eun Sun Kwon ),( Byoung Yong Koh ),( Ki Bum Myung ),( Seung ),( Hyun Cheong ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Bowen’s disease is a precancerous condition that has the potential to progress to squamous cell carcinoma. The human papillomavirus(HPV) infection is associated with bowen’s disease. And recently HPV DNA has been detected to up to 30% on the extragenital bowen’s disease lesions. A 49-year-old woman presented solitary erythematous plaque with verrucous central region on the right calf. At first the lesion was just small verrucous papule, but gradually enlarged and became erythematous. The biopsy specimen from verrucous central region showed hyperkeratosis, parakeratotic tier within the stratum corneum, acanthosis and papillomatosis with inward bending of rete ridges. These findings were appropriate for verruca. But the specimen also revealed the features of bowen’s disease. Numerous atypical and pleomorphic cells showed mitotic figures and loss of polarity throughout stratum malpighi. The upper dermis was infiltrated by inflammatory cells. And specimen was stained weakly positive for p53 and strongly positive for p16 and Ki-67. Based on the clinical and histopathologic findings, the skin lesion simultaneously had the features of bowen’s disease and verruca. Therefore we suggest that the bowen’s disease may resulted from verruca and be associated with HPV infection. Here, we present a case of bowen’s disease originated from verruca.
송형섭,박범진,권기원 忠南大學校 環境問題硏究所 1997 環境硏究 Vol.15 No.-
The purpose of this study is to obtain some useful informations for improving the campus forest landscape of Chungnam National University. Based on two kinds of surveyed data relating campus forest landscape resources and the respondents visual preference ratings, geographical features and physical characteristics of forest landscape are investigated. Twenty-four photos were taken for visual preference survey. With a total 100 respondents, relative scenic beauty of each forest scenes could be explained in terms of influence factors of physical characteristics. Three variables in model could be accounted for 65% of total variables in perceived forest scenic beauty. Results indicated that campus forest landscape must be improved greatly in the scenic views and so on. To improve current situation, some alternatives including improvement scheme and cost have to be proposed newly.
Ki Bum Kwon,Young Choi,성기혁,Chin Youb Chung,이경민,Soon-Sun Kwon,Gyeong Hee Cho,박문석 대한정형외과학회 2020 Clinics in Orthopedic Surgery Vol.12 No.1
Background: Precise measuring and monitoring of physical activity (PA) in patients with cerebral palsy (CP) are critical for assessing their PA participation and its potential health benefits. Accelerometer-based assessment of PA has been considered valid, reliable, and practical in children with CP. Therefore, we investigated the correlation between accelerometer- and questionnaire-based assessment of PA in CP patients. Methods: Nineteen patients with CP who were classified as Gross Motor Function Classification System level I–III and 84 normally developed participants were included in the study. Study participants wore an accelerometer for seven days, after which they visited the hospital and completed the International Physical Activity Questionnaire (IPAQ). CP patients and their caregivers completed the Pediatric Outcomes Data Collection Instrument (PODCI) and the Caregiver Priorities and Child Health Index of Life with Disabilities, respectively. The concurrent validity of the questionnaires was assessed. Results: In the accelerometer-based assessment, time spent in PA was significantly shorter at every intensity level in CP patients than in normally developed participants. However, PA assessed by the IPAQ was significantly higher in patients with CP, indicating that they tend to exaggerate their participation in PA. On the correlation of the assessment by the accelerometer and by the PODCI, transfer/basic mobility, sports/physical function, and happiness increased significantly as the number of steps taken and the distance travelled increased. Conclusions: In patients with CP, happiness and quality of life are associated with higher levels of PA. Thus, programs for patients with CP should focus on improving their PA.