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Analysis and Suggestions of Digital Heritage Policy
Jongwook Lee(이종욱) 한국컴퓨터정보학회 2019 韓國컴퓨터情報學會論文誌 Vol.24 No.10
본 논문은 국내외 디지털 문화 활성화 정책을 4가지 유형으로 나누었다. 또한 각 정책의 대표적인 프로젝트를 설명하고 한계를 분석하였다. 마지막으로 이러한 한계점들을 극복 할 수 있는 솔루션을 제안하였다. 최근 5G 네트워크 기술, 증강현실 및 가상현실 기술의 발달로 인한 일상생활의 변화는 문화유산의 보존 및 활용 방식에 많은 변화를 가져 왔다. 특히, 디지털 기술은 문화유산의 디지털화, 디지털 데이터의 저장 및 관리, 문화유산의 디지털 복원, 시공간 및 다감각 체험을 가능하게 하였다. 이 연구는 국내 및 국제 디지털 유산 정책을 디지털 인프라 구축, 공유 및 커뮤니케이션 플랫폼 구축, 홍보 및 시범 콘텐츠 제작 지원 정책으로 나누었다. 이 연구는 디지털 유산 정책을 분류하고 디지털 유산 정책 동향 설명하고 개선점을 제안하는데 기여한다. In this paper, we divided domestic and foreign digital cultural activation policies into four types. We also described projects of each policy and analyzed the limitations of the policy. Finally, we suggested solutions to overcome these limitations. Changes in daily life caused by the recent development of 5G network technology, augmented reality, and virtual reality technology have brought many changes in the way of preservation and utilization of cultural heritage. In particular, digital technology is used for digitization of cultural heritage, storing, and managing digital data, digitally restoring cultural heritage, and enabling time, space, multi-sensory experiences. For this purpose, new policies was required to utilize this. This study divides domestic and international digital heritage policies into digital infrastructure construction, sharing and communication platform construction, public relations, and demonstration contents production support policies. This study is meaningful in classifying the fields of digital heritage policy and introducing digital heritage policy trends. It is also meaningful to suggest ways to improve digital heritage policies through analysis of domestic and foreign cases.
Lee, Da-Hye,Lee, Jungsul,Jeon, Jongwook,Kim, Kyung-Jin,Yun, Jang-Hyuk,Jeong, Han-Seok,Lee, Eun Hui,Koh, Young Jun,Cho, Chung-Hyun Korean Society for Molecular and Cellular Biology 2018 Molecules and cells Vol.41 No.8
Angiogenesis must be precisely controlled because uncontrolled angiogenesis is involved in aggravation of disease symptoms. Vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR-2) signaling is a key pathway leading to angiogenic responses in vascular endothelial cells (ECs). Therefore, targeting VEGF/VEGFR-2 signaling may be effective at modulating angiogenesis to alleviate various disease symptoms. Oleanolic acid was verified as a VEGFR-2 binding chemical from anticancer herbs with similar binding affinity as a reference drug in the Protein Data Bank (PDB) entry 3CJG of model A coordination. Oleanolic acid effectively inhibited VEGF-induced VEGFR-2 activation and angiogenesis in HUVECs without cytotoxicity. We also verified that oleanolic acid inhibits in vivo angiogenesis during the development and the course of the retinopathy of prematurity (ROP) model in the mouse retina. Taken together, our results suggest a potential therapeutic benefit of oleanolic acid for inhibiting angiogenesis in proangiogenic diseases, including retinopathy.
( Jongwook Oh ),( Ro Woo Lee ),( Hee Ra Lee ),( Seon Bok Lee ),( Hyun Jeong Ju ),( Jungwon Park ),( Hee Ryun Park ),( Ji Hun Park ),( Seung-kyung Hann ),( Abdurrahman Almurayshid ),( Jeonghyun Shin ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: The classification of segmental vitiligo has been previously reported but more consensus on its classification is required from a large number of patients to predict its spreading and provide valuable clues to the etiology of segmental vitilig. Objectives: To classify segmental vitiligo on the whole body into several distinctive subtypes according to distributions and clinical characteristics. Methods: Total 956 patients with segmental vitiligo were enrolled. A new classification of has been proposed according to distribution patterns. The clinical course of segmental vitiligo, including recurrence rate and patterns, concurrence of non-segmental vitiligo, and treatment response, was assessed. Results: Facial and truncal segmental vitiligo was classified into each 5 patterns. Among 501 patients who had been followed up for at least one year, 55 patients (11%) showed recurrence after stabilization for more than 6 months. Most recurrence happened within the area of each subtype of segmental vitiligo in the new classification (92.7%). Conclusion: Our data suggest that segmental vitiligo has a higher recurrence rate than previously known. This new classification can help dermatologists in patient’s real care
Clinical course of segmental vitiligo through a retrospective follow-up study
( Jongwook Oh ),( Ro Woo Lee ),( Heera Lee ),( Seon Bok Lee ),( Jeonghyun Shin ),( Hee Young Kang ),( Jung Min Bae ),( Sang Ho Oh ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2
Background: Segmental vitiligo (SV) is a distinct subtype of vitiligo characterized by a unilateral distribution, early onset, and stable disease after rapid progression. However, few reports on the long-term clinical course are available. Objectives: This study aimed to reveal the clinical characteristics of SV including distribution area and occurrence of non-segmental vitiligo (NSV), and to explore the clinical course of SV. Methods: This retrospective study was conducted at four medical centers (Severance Hospital, seoul St. Vincent’s Hospital, Suwon, Ajou University Hospital, Suwon, Korea and Inha University Hospital, Incheon). A total of 507 SV patients were included. The onset age, the involvement of body part, clinical distribution, treatment response, accompanying NSV, and recurrence were assessed. Results: The median age of onset was 16 years (range: 0.4- 83.9 years), and 58.6% (n =297) were female. The head (70.2%) was the most common site of involvement, followed by trunk (16.6%), lower extremities (7.3%), and upper extremities (5.9%). After the onset of SV, 6.7% (n = 34) showed the concurrence of NSV (i.e., mixed type). Disease recurrence was observed in 12.8% (n = 65) after a median of 4.9 years (range: 0.5 - 60 years) after the first disease onset. Conclusion: This study showed that SV has a relatively higher recurrence rate than previously known and SV showed a high rate of concurrence of NSV after the onset of SV. Therefore, regular follow-ups should be recommended.
( Jongwook Oh ),( Jihee Kim ),( Young In Lee ),( Ju Hee Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Treatment of Acne scars remains a therapeutic challenge with broad range of treatment options. Especially for the atrophic scars, ablative fractional laser has demonstrated its efficacy in various reports. Meanwhile, microneedle radiofrequency (RF) can allow a more selective microthermal zone of the dermis without epidermal damage. Objectives: The aim of this study was to analyze the effect and safety of combination treatment with AFL and microneedle RF in acnes and postacne scars. Methods: The photographs of 50 patients with acnes and post-acne scars who received microneedle RF treatments were retrospectively reviewed. The reduction in numbers of active acne lesions and postacne scars, overall improvement degrees were evaluated by two dependent dermatologists, and patients’ satisfaction levels were evaluated from the patients. Results: The active acne lesions, global improvement scale and patient satisfaction levels showed significant improvement in all treated patients, although there was no significant difference in these parameters between RF alone group and combination treatment group. However, the reductions of box scars and rolling scars showed significant improvement in the combination therapy group compared to the RF alone group. Conclusion: The combination treatment with AFL and microneedle RF therapy is effective in treatment of inflammatory acne lesions and postacne scars.
Lee, Jaehyun,Lee, Yong-Sang,Kim, Seungho,Jeong, Hyocheol,Koo, Kee-Kahb,Park, Jongwook American Scientific Publishers 2016 Journal of Nanoscience and Nanotechnology Vol.16 No.10
<P>9,10-Bis(3 '',5 ''-diphenylbiphenyl-4'-yl)anthracene [TAT] and a new anthracene derivative of 2-tertbutyl-9,10-bis(3 '',5 ''-diphenylbiphenyl-4'-yl) anthracene [T-TAT] by introduced t-butyl group were synthesized. OLED devices of TAT and T-TAT were fabricated by solution process. Two materials indicated typical absorption peaks of anthracene in the range of 350 nm and 400 nm. The PL wavelengths were 436 nm (TAT) and 439 nm (T-TAT), respectively. The OLED device structure applied to the solution process was as follows: ITO/PEDOT: PSS (40 nm)/PVK (15 nm)/synthesized materials (45 nm)/TPBi (20 nm)/LiF (1 nm)/Al (200 nm). The luminance efficiency of the synthesized materials at 20 mA/cm(2) were measured 0.59 cd/A for TAT and 0.84 cd/A for T-TAT, respectively. In case of the CIE values, TAT and T-TAT exhibited (0.150, 0.097) and (0.147, 0.097). As a result, more improved efficiency was shown with the device in a material including t-butyl group to TAT core part, when the devices were prepared by solution process.</P>